Cited by 74Virtual Reality Applications and ImpactsAnxiety, Depression, Psychometrics, Treatment, Cognitive ProcessesDigital Mental Health Interventions

The potential of virtual reality as anxiety management tool: a randomized controlled study in a sample of patients affected by generalized anxiety disorder

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Gorini, Alessandra, Riva, Giuseppe·2008·Trials

Abstract

BACKGROUND: Generalized anxiety disorder (GAD) is a psychiatric disorder characterized by a constant and unspecific anxiety that interferes with daily-life activities. Its high prevalence in general population and the severe limitations it causes, point out the necessity to find new efficient strategies to treat it. Together with the cognitive-behavioural treatments, relaxation represents a useful approach for the treatment of GAD, but it has the limitation that it is hard to be learned. To overcome this limitation we propose the use of virtual reality (VR) to facilitate the relaxation process by visually presenting key relaxing images to the subjects. The visual presentation of a virtual calm scenario can facilitate patients' practice and mastery of relaxation, making the experience more vivid and real than the one that most subjects can create using their own imagination and memory, and triggering a broad empowerment process within the experience induced by a high sense of presence. According to these premises, the aim of the present study is to investigate the advantages of using a VR-based relaxation protocol in reducing anxiety in patients affected by GAD. METHODS/DESIGN: The trial is based on a randomized controlled study, including three groups of 25 patients each (for a total of 75 patients): (1) the VR group, (2) the non-VR group and (3) the waiting list (WL) group. Patients in the VR group will be taught to relax using a VR relaxing environment and audio-visual mobile narratives; patients in the non-VR group will be taught to relax using the same relaxing narratives proposed to the VR group, but without the VR support, and patients in the WL group will not receive any kind of relaxation training. Psychometric and psychophysiological outcomes will serve as quantitative dependent variables, while subjective reports of participants will be used as qualitative dependent variables. CONCLUSION: We argue that the use of VR for relaxation represents a promising approach in the treatment of GAD since it enhances the quality of the relaxing experience through the elicitation of the sense of presence. This controlled trial will be able to evaluate the effects of the use of VR in relaxation while preserving the benefits of randomization to reduce bias. TRIAL REGISTRATION: NCT00602212 (ClinicalTrials.gov).

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  • The outcomes from the IM-VRCBT group are concordant to other investigations indicating that exposure and relaxation VR scenarios are similarly effective to the classical, face-to-face version of these strategies in reducing GAD symptoms.

    “Consequently, the outcomes from the IM-VRCBT group are concordant to other investigations indicating that exposure and relaxation VR scenarios are similarly effective to the classical, face-to-face version of these strategies in reducing GAD symptoms (Gorini and Riva, 2008; Meyerbröker and Emmelkamp, 2010; Guitard et al., 2019).”

    From Standard CBT versus integrative and multimodal CBT assisted by virtual-reality for generalized anxiety disorder (2022) · cites this paper as Gorini and Riva, 2008

    The Methods (Clinical protocol; page not available) describe VR relaxation and exposure for patients with GAD alongside a non-VR comparison group. But the Discussion says the trial will evaluate VR’s effects; this paper reports no outcomes showing that VR scenarios are similarly effective to face-to-face strategies in reducing GAD symptoms. (LLM, conf=0.86)

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Authors
Gorini, A., & Riva, G.
Affiliations
  • IRCCS Istituto Auxologico Italiano (IT)
  • Università Cattolica del Sacro Cuore (IT)
Corresponding author
Gorini, Alessandra
Venue
Trials
Published
2008-05-05
Volume
9
Issue
1
Pages
25-25
ISSN
1745-6215 (ISSN-L)
OpenAlex
W2169884097
Cited by
74
References
5
Citations by year
2026: 4 · 2025: 4 · 2024: 5 · 2023: 4 · 2022: 3 · 2021: 7 · 2020: 1 · 2019: 6 · 2018: 3 · 2017: 5 · 2016: 2 · 2015: 2 · 2014: 7 · 2013: 3 · 2012: 1
FWCI
13.86
Type
journal article
Language
en
Open access
Locations
  • Trials (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
Funders
  • European Commission
  • Ministero dell’Istruzione, dell’Università e della Ricerca (RBIN04BC5C)
Topics
  • Physical Sciences › Computer Science › Human-Computer Interaction › Virtual Reality Applications and Impacts
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
  • Social Sciences › Psychology › Applied Psychology › Digital Mental Health Interventions
Keywords
virtual reality, generalized anxiety disorder, relaxation training, anxiety reduction, presence, virtual worlds, cognitive behavioral therapy

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