Why sex and gender matter in implementation research
Open accessAbstract
BACKGROUND: There has been a recent swell in activity by health research funding organizations and science journal editors to increase uptake of sex and gender considerations in study design, conduct and reporting in order to ensure that research results apply to everyone. However, examination of the implementation research literature reveals that attention to sex and gender has not yet infiltrated research methods in this field. DISCUSSION: The rationale for routinely considering sex and gender in implementation research is multifold. Sex and gender are important in decision-making, communication, stakeholder engagement and preferences for the uptake of interventions. Gender roles, gender identity, gender relations, and institutionalized gender influence the way in which an implementation strategy works, for whom, under what circumstances and why. There is emerging evidence that programme theories may operate differently within and across sexes, genders and other intersectional characteristics under various circumstances. Furthermore, without proper study, implementation strategies may inadvertently exploit or ignore, rather than transform thinking about sex and gender-related factors. Techniques are described for measuring and analyzing sex and gender in implementation research using both quantitative and qualitative methods. The present paper describes the application of methods for integrating sex and gender in implementation research. Consistently asking critical questions about sex and gender will likely lead to the discovery of positive outcomes, as well as unintended consequences. The result has potential to strengthen both the practice and science of implementation, improve health outcomes and reduce gender inequities.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Symbolic contexts of who is valued and afforded dignity, such as bodily autonomy, reflect inequitable gender norms whereby AGYW are largely targets of violence perpetrated by men.
“In this way, symbolic contexts of who is valued and afforded dignity -such as bodily autonomy -re fl ect inequitable gender norms whereby AGYW are largely targets of violence perpetrated by men (Tannenbaum et al . 2016).”
From Water insecurity and sexual and gender-based violence among refugee youth: qualitative insights from a humanitarian setting in Uganda (2022) · cites this paper as Tannenbaum et al . 2016
The Discussion section describes gendered power relations affecting women’s decisions and reports cases of spousal abuse. It does not address bodily autonomy or dignity, or establish that adolescent girls and young women (AGYW) are largely targets of violence perpetrated by men. (LLM, conf=0.84)
Experimental — accuracy not yet measured
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Durlak, J. A., & DuPre, E. P. (2008) · American Journal of Community Psychology · doi:10.1007/s10464-008-9165-0 · Cited by 5,304 · see citing works
Cane, J., O’Connor, D., & Michie, S. (2012) · Implementation Science · doi:10.1186/1748-5908-7-37 · Cited by 4,888 · cited 2× · see citing works
“We also thank Krystle van Hoof, Assistant Director of the CIHR Institute of Gender and Health for her thoughtful comments, and Justin Presseau, Scientist at the Ottawa Hospital Research Institute for insightful discussions about sex and gender in implementation research and the Theoretical Domains Framework.”
BackgroundMaking sense of implementation theories, models and frameworks
Nilsen, P. (2015) · Implementation Science · doi:10.1186/s13012-015-0242-0 · Cited by 4,447 · see citing works
Realist review - a new method of systematic review designed for complex policy interventions
Pawson, R., Greenhalgh, T., Harvey, G., & Walshe, K. (2005) · Journal of Health Services Research & Policy · doi:10.1258/1355819054308530 · Cited by 3,190 · see citing works
Policy: NIH to balance sex in cell and animal studies
Clayton, J. A., & Collins, F. S. (2014) · Nature · doi:10.1038/509282a · Cited by 1,816 · see citing works
Development of the Conformity to Masculine Norms Inventory.
Mahalik, J. R., Locke, B. D., Ludlow, L. H., Diemer, M. A., Scott, R. P. J., Gottfried, M., & Freitas, G. (2003) · Psychology of Men & Masculinity · doi:10.1037/1524-9220.4.1.3 · Cited by 1,295 · see citing works
Improving Patient Care: The Implementation of Change in Health Care
(2013) · doi:10.1002/9781118525975 · Cited by 506 · see citing works
Sex inclusion in basic research drives discovery
Klein, S. L., Schiebinger, L., Stefanick, M. L., Cahill, L., Danska, J., de Vries, G. J., Kibbe, M. R., McCarthy, M. M., Mogil, J. S., Woodruff, T. K., et al. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1502843112 · Cited by 238 · see citing works
Flagged first, then by citations
Research works printed but not linked: 57
- [1]Mazure CM Jones DP Twenty years and still counting: including women as participants and studying sex and gender in biomedical research BMC Women’s Health 2015 15 94 10.1186/s12905-015-0251-9 26503700 PMC4624369 · DOI
- [3]Gates MF Putting women and girls at the center of development Science 2014 345 6202 25214610
- [5]Johnson J Sharman Z Vissandjée B Stewart DE Does a change in health research funding policy related to the integration of sex and gender have an impact? PLoS One 2014 9 6 e99900 10.1371/journal.pone.0099900 24964040 PMC4070905 · DOI
- [7]Clayton JA Studying both sexes: a guiding principle for biomedicine FASEB J 2015 30 519 524 10.1096/fj.15-279554 26514164 PMC4714546 · DOI · Paper page
- [8]Tannenbaum C Schwarz JM Clayton JA de Vries GJ Sullivan C Evaluating sex as a biological variable in preclinical research: the devil in the details Biol Sex Differ 2016 7 13 10.1186/s13293-016-0066-x 26870316 PMC4750169 · DOI
- [9]Pollitzer E, Buitendijk S, Hermann C, Muhlenbruch B, Schiebinger L. Integrating Gender in Horizon 2020. Pen Sci Technol. 2015;15:1–3. https://s3-eu-west-1.amazonaws.com/data.epws.org/DOCUMENTS/WEBSITE2016/PRESS/ST15+E+Pollitzer+et+al+1022+Atl_CH.pdf. Accessed 25 Oct 2016.
- [10]Johnson JL Beaudet A Sex and gender reporting in health research: why Canada should be a leader Can J Public Health 2012 104 e80 1 23618110 PMC6973991
- [11]Heidari S Babor TF De Castro P Tort S Curno M Sex and gender equity in research: rationale for the SAGER guidelines and recommended use Res Integr Peer Rev 2016 1 1 1 9 10.1186/s41073-016-0006-7 29451543 PMC5793986 · DOI
- [12]Straus SE, Tetroe J, Graham ID, editors. Knowledge translation in health care: moving from evidence to practice. 2nd Edition. West Sussex: Wiley-Blackwell; 2013. p. 424.
- [14]Brownson RC, Colditz GA, Proctor EK. Dissemination and implementation research in health: Translating science to practice. New York: Oxford University Press; 2012. p. 528.
- [15]Yancey AT, Gleen BA, Bell-Lewis L, Ford CL. Dissemination and implementation research in populatons with health disaparities. In: Brownson RC, Colditz GA, Proctor EK. Dissemination and implementation research in health: Translating science to practice. New York: Oxford University Press; 2012. p. 528.
- [16]Aarons GA Ehrhart MG Farahnak LR Hurlburt MS Leadership and organizational change for implementation (LOCI): a randomized mixed method pilot study of a leadership and organization development intervention for evidence-based practice implementation Implement Sci 2015 10 11 10.1186/s13012-014-0192-y 25592163 PMC4310135 · DOI · Paper page
- [18]Cochrane LJ Olson CA Murray S Dupuis M Tooman T Hayes S Gaps between knowing and doing: understanding and assessing the barriers to optimal health care J Contin Educ Health Prof 2007 27 94 102 10.1002/chp.106 17576625 · DOI · Paper page
- [21]Francis JJ O’Connor D Curran J Theories of behaviour change synthesized into a set of theoretical groupings: introducing a thematic series on the theoretical domains framework Implement Sci 2012 7 35 10.1186/1748-5908-7-35 22531601 PMC3444902 · DOI · Paper page
- [22]Sarmast H Mosavianpour M Collet J-P Kissoon N TDF (Theoretical Domain Framework): how inclusive are TDF domains and constructs compared to other tools for assessing barriers to change? BMC Health Services Res 2014 14 Suppl 2 81 10.1186/1472-6963-14-S2-P81 · DOI
- [24]Runnels V Tudiver S Doull M Boscoe M The challenges of including sex/gender analysis in systematic reviews: a qualitative survey Syst Rev 2014 3 33 10.1186/2046-4053-3-33 24720875 PMC3990268 · DOI
- [25]Doull M Runnels V Tudiver S Boscoe M Appraising the evidence: applying sex and gender based analysis (SGBA) to Cochrane systematic reviews on cardiovascular diseases J Women’s Health 2010 19 997 1003 10.1089/jwh.2009.1626 20384450 · DOI
- [26]Effective Practice and Organisation of Care (EPOC). Equity considerations in EPOC reviews. EPOC Resources for review authors. Oslo: Norwegian Knowledge Centre for the Health Services; 2013. Available at: http://epoc.cochrane.org/sites/epoc.cochrane.org/files/uploads/18%20Equity%20considerations%20in%20EPOC%20reviews%202013%2008%2012_1.pdf. Accessed 14 April 2016.
- [27]Ryan R. Cochrane Consumers and Communication Review Group. ‘Cochrane Consumers and Communication Review Group reviews: how to consider equity issues’. 2013. Available at: http://cccrg.cochrane.org/sites/cccrg.cochrane.org/files/uploads/Equity.pdf Accessed 14 April 2016.
- [29]Wizeman TM Pardue M Institute of Medicine. Exploring the biological contributions to human health: Does sex matter? 2001 Washington, DC The National Academies Press 25057540
- [32]Schiebinger L Stefanick ML Gender matters in biological research and medical practice J Am Coll Cardiol 2016 67 2 136 8 10.1016/j.jacc.2015.11.029 26791058 · DOI
- [33]Morgan R George A Ssali S Hawkins K Molyneux S Theobald S How to do (or not to do)… gender analysis in health systems research Health Policy Plan 2016 31 8 1069 78 10.1093/heapol/czw037 27117482 PMC6616028 · DOI
- [34]Rossi AM Pilote L Let’s Talk About Sex…and Gender! Circ Cardiovasc Qual Outcomes 2016 9 2 Suppl 1 S100 1 10.1161/CIRCOUTCOMES.116.002660 26908854 · DOI
- [36]Bauer GR Incorporating intersectionality theory into population health research methodology: challenges and the potential to advance health equity Soc Sci Med 2014 110 10 17 10.1016/j.socscimed.2014.03.022 24704889 · DOI
- [37]Bowleg L The problem with the phrase women and minorities: intersectionality-an important theoretical framework for public health Am J Public Health 2012 102 1267 73 10.2105/AJPH.2012.300750 22594719 PMC3477987 · DOI · Paper page
- [38]O’Neil J Tabish H Welch V Petticrew M Pottie L Clarke M Evans T Pardo Pardo J Waters E White H Tugwell P Applying an equity lens to interventions: using PROGRESS ensures consideration of socially stratifying factors to illuminate inequities in health J Clin Epidemiol 2014 67 56 64 10.1016/j.jclinepi.2013.08.005 24189091 · DOI · Paper page
- [39]Westbrook L Saperstein A New categories are not enough: rethinking the measurement of sex and gender in social surveys Gender Soc 2015 29 534 560 10.1177/0891243215584758 · DOI · Paper page
- [40]Scheim AI Bauer GR Sex and gender diversity among transgender persons in Ontario, Canada: results from a respondent-driven sampling survey J Sex Res 2015 52 1 14 10.1080/00224499.2014.893553 24750105 PMC4299544 · DOI
- [41]Einstein G. Measuring Biological Sex. In Oliffe J, Greaves L, editors. Designing and Conducting gender sex and health research. Washington D.C.: SAGE; 2012. pp. 85-101.
- [43]Oliffe J, Greaves L. (eds). Designing and Conducting Gender Sex and Health Research. Washington D.C.: SAGE; 2012. p. 280.
- [44]Pelletier R Khan NA Cox J Daskalopoulou SS Eisenberg MJ Bacon SL Lavoie KL Daskupta K Rabi D Humphries KH Norris CM Thanassoulis G Behlouli H Pilote L GENESIS-PRAXY Investigators Sex versus gender-related characteristics: which predicts outcome after acute coronary syndrome in the young? J Am Coll Cardiol 2016 67 127 35 10.1016/j.jacc.2015.10.067 26791057 · DOI · Paper page
- [45]Smith PM Koehoorn M Measuring gender when you don’t have a gender measure: constructing a gender index using survey data Int J Equity Health 2016 15 82 10.1186/s12939-016-0370-4 27233478 PMC4884354 · DOI
- [46]Pelletier R Ditto B Pilote L A composite measure of gender and its association with risk factors in patients with premature acute coronary syndrome Psychosom Med 2015 77 517 26 10.1097/PSY.0000000000000186 25984818 · DOI
- [47]Pawson R. The science of evaluation: a realist manifesto. Washington D.C.: SAGE; 2013. p. 240
- [49]Eagly AH Johannesen-Schmidt MC van Engen ML Transformational, transactional, and laissez-faire leadership styles: a meta-analysis comparing women and men Psychol Bull 2003 129 569 91 10.1037/0033-2909.129.4.569 12848221 · DOI
- [50]Cuadrado I García-Ael C Molero F Gender-typing of leadership: evaluations of real and ideal managers Scand J Psychol 2015 56 236 44 10.1111/sjop.12187 25558896 · DOI
- [51]Bart C McQueen G Why women make better directors Int J Business Govern Ethics 2013 8 93 99 10.1504/IJBGE.2013.052743 · DOI
- [53]Zhu LL Brescoli VL Newman GE Uhlmann EL Macho nachos: The implicit effects of gendered food packaging on preferences for healthy and unhealthy foods Soc Psychol 2015 46 182 196 10.1027/1864-9335/a000226 · DOI
- [54]Brown CS Stone EA Gender stereotypes and discrimination: how sexism impacts development Adv Child Dev Behav 2016 50 105 33 10.1016/bs.acdb.2015.11.001 26956071 · DOI
- [55]Stanley N Ellis J Farrelly N Hollinghurst S Downe S Preventing domestic abuse for children and young people: a review of school-based interventions Child Youth Serv Rev 2015 59 120 131 10.1016/j.childyouth.2015.10.018 26740731 PMC4678286 · DOI
- [56]Green JD, Kearns JC, Ledoux AM, Addis ME, Marx BP. The Association Between Masculinity and Nonsuicidal Self-Injury. Am J Mens Health. 2015. [Epub ahead of print] PMC5734538 26718774
- [57]Creighton GM, Oliffe JL, Lohan M, Ogrodniczuk JS, Palm E. “Things I did not know”: Retrospectives on a Canadian rural male youth suicide using an instrumental photovoice case study. Health (London). 2016. [Epub ahead of print] PMC5639980 26979983
- [58]Oliffe JL Ogrodniczuk JS Gordon SJ Creighton G Kelly MT Black N Mackenzie C Stigma in male depression and suicide: a Canadian sex comparison study Community Ment Health J 2016 52 302 10 10.1007/s10597-015-9986-x 26733336 PMC4805721 · DOI
- [59]Krysinska K Batterham PJ Christensen H Differences in the effectiveness of psychosocial interventions for suicidal ideation and behaviour in women and men: a systematic review of randomised controlled trials Arch Suicide Res 2016 16 1 21 10.1080/13811118.2016.1162246 26983580 · DOI
- [60]Tannenbaum C Lexchin J Tamblyn R Romans S Indicators for measuring mental health: towards better surveillance Health Policy 2009 5 e177 86 PMC2805147 21037820
- [61]Hirsh AT Hollingshead NA Matthias MS Bair MJ Kroenke K The influence of patient sex, provider sex, and sexist attitudes on pain treatment decisions J Pain 2014 15 551 9 10.1016/j.jpain.2014.02.003 24576430 · DOI
- [62]Fraenkel L Suter L Weis L Hawker GA Variability in recommendations for total knee arthroplasty among rheumatologists and orthopedic surgeons J Rheumatol 2014 41 47 52 10.3899/jrheum.130762 24293580 PMC3880398 · DOI
- [63]Kululanga L Sundby J Malata A Chirwa E Striving to promote male involvement in maternal health care in rural and urban settings in Malawi - a qualitative study Reprod Health 2011 8 36 10.1186/1742-4755-8-36 22133209 PMC3245422 · DOI
- [64]Jennings L Gagliardi L Influence of health interventions on gender relations in developing countries: a systematic review Int J Equity Health 2013 12 85 10.1186/1475-9276-12-85 24131553 PMC4015705 · DOI · Paper page
- [66]Greaves L, Pederson A, Poole N (Eds). Making It Better: Gender Transformative Health Promotion. Canadian Scholar’s Press/Women’s Press. 2014. Available at http://promotinghealthinwomen.ca/book/. Accessed 14 April 2016.
- [67]Greaves L Can tobacco control be transformative? Reducing gender inequity and tobacco use among vulnerable populations Int J Environ Res Public Health 2014 11 792 803 10.3390/ijerph110100792 24402065 PMC3924474 · DOI
- [68]Bottorff JL Kalaw C Johnson JL Stewart M Greaves L Carey J Couple dynamics during women’s tobacco reduction in pregnancy and postpartum Nicotine Tob Res 2006 4 499 509 10.1080/14622200600789551 16920647 · DOI
- [69]Greaves L Kalaw C Bottorff J Case studies of power and control related to tobacco use during pregnancy Women’s Health Issues 2007 17 325 332 10.1016/j.whi.2007.06.001 17692535 · DOI
- [71]Dalkin SM Greenhalgh J Jones D Cunningham B Lhussier M What’s in a mechanism? Development of a key concept in realist evaluation Implement Sci 2015 10 49 10.1186/s13012-015-0237-x 25885787 PMC4408605 · DOI · Paper page
- [74]Bem SL On the utility of alternative procedures for assessing psychological androgyny J Consult Clin Psychol 1977 45 196 205 10.1037/0022-006X.45.2.196 850004 · DOI · Paper page
- [75]Spence JT Helmreich R Stapp J Ratings of self and peers on sex role attributes and their relation to self-esteem and conceptions of masculinity and femininity J Pers Soc Psychol 1975 32 29 39 10.1037/h0076857 1206468 · DOI
- [77]Sörlin A Lindholm L Ng N Öhman A Gender equality in couples and self-rated health-A survey study evaluating measurements of gender equality and its impact on health Int J Equity Health 2011 10 37 47 10.1186/1475-9276-10-37 21871087 PMC3167759 · DOI
Cited by
Sorted by citations
Hinshaw, S. P., Nguyen, P. T., O’Grady, S. M., & Rosenthal, E. A. (2022) · Journal of Child Psychology and Psychiatry · doi:10.1111/jcpp.13480 · Cited by 424 · see citing works
Welch, V. A., Akl, E. A., Guyatt, G., Pottie, K., Eslava-Schmalbach, J., Ansari, M. T., de Beer, H., Briel, M., Dans, T., Dans, I., et al. (2017) · Journal of Clinical Epidemiology · doi:10.1016/j.jclinepi.2017.01.014 · Cited by 131 · see citing works
“Implementation research needs to consider sex and gender, as well as other characteristics which may influence both provision and uptake of proven effective interventions [33].”
BackgroundDe Simone, J. J. (2020) · Teacher Development · doi:10.1080/13664530.2020.1780302 · Cited by 26 · see citing works
Logie, C. H., Okumu, M., Coelho, M., Loutet, M. G., Narasimhan, M., Lukone, S. O., Kisubi, N., Musoke, D. K., Kyambadde, P., Dorea, C., et al. (2022) · Journal of Water Sanitation and Hygiene for Development · doi:10.2166/washdev.2022.236 · Cited by 19 · see citing works
- Authors
- Tannenbaum, C., Greaves, L., & Graham, I. D.
- Affiliations
- Canadian Institutes of Health Research (CA)
- British Columbia Centre of Excellence for Women's Health (CA)
- University of Ottawa (CA)
- Corresponding author
- Tannenbaum, Cara
- Venue
- BMC Medical Research Methodology
- Published
- 2016-10-27
- Volume
- 16
- Issue
- 1
- Pages
- 145-145
- ISSN
- 1471-2288 (ISSN-L)
- PMC
- PMC5084413
- OpenAlex
- W2544651403
- Cited by
- 386
- References
- 8
- Citations by year
- 2026: 22 · 2025: 37 · 2024: 56 · 2023: 51 · 2022: 62 · 2021: 63 · 2020: 45 · 2019: 25 · 2018: 17 · 2017: 8
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- BMC Medical Research Methodology (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- uO Research (University of Ottawa) (submittedVersion, public-domain)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Funders
- Ottawa Hospital Research Institute
- Bangor University
- Canadian Institutes of Health Research (FDN# 143237, 143237)
- Institute of Gender and Health
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Sex and Gender in Healthcare
- Health Sciences › Health Professions › General Health Professions › Health Policy Implementation Science
- Social Sciences › Gender Studies › Diversity and Career in Medicine
- Keywords
- sex and gender, implementation research, gender roles, gender identity, gender relations, intersectionality, program theory, stakeholder engagement, gender inequity, sex differences in health
- MeSH terms
- Female, Humans, Male, Research Design, Sex Factors, Sex Distribution
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review