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Cited by 665

The DOI matches its Crossref record; 208 of the 208 references it cites were found in a registry or an index.

Resistance to cancer chemotherapy: failure in drug response from ADME to P-gp

Open access
Alfarouk, Khalid O, Stock, Christian-Martin, Taylor, Sophie, Walsh, Megan, Muddathir, Abdel Khalig, Verduzco, Daniel, Bashir, Adil H H, Mohammed, Osama Y, Elhassan, Gamal O, Harguindey, Salvador, Reshkin, Stephan J, Ibrahim, Muntaser E, Rauch, Cyril·2015·Cancer Cell International

Abstract

Cancer chemotherapy resistance (MDR) is the innate and/or acquired ability of cancer cells to evade the effects of chemotherapeutics and is one of the most pressing major dilemmas in cancer therapy. Chemotherapy resistance can arise due to several host or tumor-related factors. However, most current research is focused on tumor-specific factors and specifically genes that handle expression of pumps that efflux accumulated drugs inside malignantly transformed types of cells. In this work, we suggest a wider and alternative perspective that sets the stage for a future platform in modifying drug resistance with respect to the treatment of cancer.

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Crossref · 10.1186/s12935-015-0221-1

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Metadata

Authors
Alfarouk, K. O., Stock, C.-M., Taylor, S., Walsh, M., Muddathir, A. K., Verduzco, D., Bashir, A. H. H., Mohammed, O. Y., Elhassan, G. O., Harguindey, S., Reshkin, S. J., Ibrahim, M. E., & Rauch, C.
Venue
Cancer Cell International
Published
2015-07-15
Volume
15
Issue
1
Pages
71-71
ISSN
1475-2867 (ISSN-L)
OpenAlex
W1581731557
Cited by
665
References
208
FWCI
8.84
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: Resistance to cancer chemotherapy: failure in drug response from ADME to P-gp. https://app.cochat.ai/papers/10.1186/s12935-015-0221-1
The paper
Alfarouk, K. O., Stock, C.-M., Taylor, S., Walsh, M., Muddathir, A. K., Verduzco, D., Bashir, A. H. H., Mohammed, O. Y., Elhassan, G. O., Harguindey, S., Reshkin, S. J., Ibrahim, M. E., & Rauch, C. (2015). Resistance to cancer chemotherapy: failure in drug response from ADME to P-gp. Cancer Cell International. https://doi.org/10.1186/s12935-015-0221-1

Data sources

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.