Orthostatic intolerance symptoms are associated with depression and diminished quality of life in patients with postural tachycardia syndrome
Open accessAbstract
BACKGROUND: Patients with postural tachycardia syndrome often appear depressive and report diminished quality of life (QOL). In the current study, we first evaluated if the maximal heart rate (HR) increment after standing is associated with the clinical symptoms in patients with excessive orthostatic tachycardia (OT). Next, we investigated the correlations among the symptoms of orthostatic intolerance (OI), depression, and health-related QOL in these patients. Finally we assessed if patients with minimal OI symptoms suffer from depression or diminished QOL. METHODS: We performed a comprehensive questionnaire-based assessment of symptoms in 107 patients with excessive OT with a ≥ 30 beats/min heart rate increment (or ≥ 40 beats/min in individuals aged between 12 and 19) within 10 min after standing up. An existing orthostatic intolerance questionnaire (OIQ), the Beck depression inventory-II (BDI-II), and the 36 Item Short-Form Health Survey were completed prior to any treatment. Correlation analyses among the items of the questionnaires and other parameters were performed. Additionally, patients with minimal OI symptoms were analysed separately. RESULTS: The maximal orthostatic HR increment was not associated with the clinical symptoms. The OI symptoms were significantly correlated with depression and diminished QOL. The BDI-II score demonstrated a positive linear relationship with total OIQ score (r = 0.516), and both physical and mental component summary scales of SF-36 showed a negative linear relationship with total OIQ score (r = -0.542 and r = -0.440, respectively; all p <0.001). Some OI symptoms were more strongly associated with depression, and others were more strongly related to QOL. Chest discomfort and concentration difficulties were the most influential OI symptoms for depression, while nausea and concentration difficulties were the most influential symptoms for physical and mental QOL, respectively. Dizziness and headache were the two most common complaints in patients with mild to moderate OI symptoms. In addition, subjects with minimal OI symptoms also had considerable deterioration in QOL. CONCLUSION: The OI symptoms, but not the maximal HR increment, are significantly correlated with depression and diminished QOL in patients with excessive OT. Therefore, pervasive history taking is important when encountering patients with excessive OT.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Mental functioning components had small to medium correlations with symptom burden.
“Mental functioning components (PROMIS mental health T-score and SF-36 mental component) had small”
From Self-reported symptom burden in postural orthostatic tachycardia syndrome (POTS): A narrative review of observational and interventional studies (2023) · cites this paper as Moon et al., 2016
The Results section reports that the SF-36 mental component summary score correlated with orthostatic symptom burden (r = −0.436; r = −0.198 after adjustment), consistent with a small-to-medium association. The paper does not report a PROMIS mental health T-score, so it does not support that component of the claim. No page number is available in our copy. (LLM, conf=0.88)
Experimental — accuracy not yet measuredBoth physical and mental component summary scales of SF-36 showed a negative linear relationship with total OIQ scores.
“Both physical and mental component summary scales of SF-36 showed a negative linear relationship with total OIQ scores (Moon et al., 2016”
From Self-reported symptom burden in postural orthostatic tachycardia syndrome (POTS): A narrative review of observational and interventional studies (2023) · cites this paper as Moon et al., 2016
Two studies found medium correlations between higher symptom burden scores and higher depression scores, and one large study also found this association.
“Two found medium correlations (Benrud-Larson et al., 2003”
From Self-reported symptom burden in postural orthostatic tachycardia syndrome (POTS): A narrative review of observational and interventional studies (2023) · cites this paper as Moon et al., 2016
Some OI symptoms were more strongly associated with depression, including chest discomfort and concentration difficulties.
“One medium quality study reported that some OI symptoms were more strongly associated with depression including chest discomfort and concentration difficulties (Moon et al., 2016”
From Self-reported symptom burden in postural orthostatic tachycardia syndrome (POTS): A narrative review of observational and interventional studies (2023) · cites this paper as Moon et al., 2016
One medium quality study observed no significant correlation between the degree of orthostatic heart rate increment and symptom burden.
“One medium quality study observed no significant correlation between the degree of orthostatic heart rate increment and symptom burden (Moon et al., 2016”
From Self-reported symptom burden in postural orthostatic tachycardia syndrome (POTS): A narrative review of observational and interventional studies (2023) · cites this paper as Moon et al., 2016
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Comparison of Beck Depression Inventories -IA and -II in psychiatric outpatients
Beck, A. T., Steer, R. A., Ball, R., & Ranieri, W. F. (1996) · Journal of Personality Assessment · doi:10.1207/s15327752jpa6703_13 · Cited by 5,965 · see citing works
Short form 36 (SF36) health survey questionnaire: normative data for adults of working age.
Jenkinson, C., Coulter, A., & Wright, L. (1993) · BMJ · doi:10.1136/bmj.306.6890.1437 · Cited by 1,714 · see citing works
Freeman, R., Wieling, W., Axelrod, F. B., Benditt, D. G., Benarroch, E., Biaggioni, I., Cheshire, W. P., Chelimsky, T., Cortelli, P., Gibbons, C. H., et al. (2011) · Clinical Autonomic Research · doi:10.1007/s10286-011-0119-5 · Cited by 1,697 · see citing works
Freeman, R., Wieling, W., Axelrod, F. B., Benditt, D. G., Benarroch, E., Biaggioni, I., Cheshire, W. P., Chelimsky, T., Cortelli, P., Gibbons, C. H., et al. (2011) · Autonomic Neuroscience · doi:10.1016/j.autneu.2011.02.004 · Cited by 1,243 · see citing works
Sheldon, R. S., Grubb, B. P., Olshansky, B., Shen, W.-K., Calkins, H., Brignole, M., Raj, S. R., Krahn, A. D., Morillo, C. A., Stewart, J. M., et al. (2015) · Heart Rhythm · doi:10.1016/j.hrthm.2015.03.029 · Cited by 1,013 · see citing works
Depression but not seizure frequency predicts quality of life in treatment-resistant epilepsy
Boylan, L. S., Flint, L. A., Labovitz, D., Jackson, S., Starner, K., & Devinsky, O. (2004) · Neurology · doi:10.1212/01.wnl.0000103282.62353.85 · Cited by 643 · see citing works
Diabetes, Depression, and Quality of Life
Goldney, R. D., Phillips, P., Fisher, L. J., & WILSON, D. H. (2004) · Diabetes Care · doi:10.2337/diacare.27.5.1066 · Cited by 612 · see citing works
Postural orthostatic tachycardia syndrome: the Mayo clinic experience
Thieben, M. J., Sandroni, P., Sletten, D. M., Benrud-Larson, L. M., Fealey, R. D., Vernino, S., Low, P. A., Lennon, V. A., & Shen, W.-K. (2007) · Mayo Clinic Proceedings · doi:10.1016/s0025-6196(11)61027-6 · Cited by 516 · see citing works
Quality of life in multiple sclerosis: the impact of depression, fatigue and disability
Amato, M. P., Ponziani, G., Rossi, F., Liedl, C. L., Stefanile, C., & Rossi, L. (2001) · Multiple Sclerosis Journal · doi:10.1177/135245850100700511 · Cited by 506 · see citing works
Postural tachycardia syndrome: a heterogeneous and multifactorial disorder
Benarroch, E. E. (2012) · Mayo Clinic Proceedings · doi:10.1016/j.mayocp.2012.08.013 · Cited by 370 · see citing works
Suárez, G. A., Opfer-Gehrking, T. L., Offord, K. P., Atkinson, E. J., O’Brien, P. C., & Low, P. A. (1999) · Neurology · doi:10.1212/wnl.52.3.523 · Cited by 315 · see citing works
Grubb, B. P. (2008) · Circulation · doi:10.1161/circulationaha.107.761643 · Cited by 224 · see citing works
Quality of Life in Patients With Postural Tachycardia Syndrome
Benrud-Larson, L. M., Dewar, M. S., Sandroni, P., Rummans, T. A., Haythornthwaite, J. A., & Low, P. A. (2002) · Mayo Clinic Proceedings · doi:10.4065/77.6.531 · Cited by 217 · see citing works
Fu, Q., VanGundy, T. B., Shibata, S., Auchus, R. J., Williams, G. H., & Levine, B. D. (2011) · Hypertension · doi:10.1161/hypertensionaha.111.172262 · Cited by 175 · see citing works
Acetylcholinesterase inhibition improves tachycardia in postural tachycardia syndrome
Raj, S. R., Black, B. K., Biaggioni, I., Harris, P. A., & Robertson, D. (2005) · Circulation · doi:10.1161/circulationaha.104.497594 · Cited by 171 · see citing works
Endurance Exercise Training in Orthostatic Intolerance
Winker, R., Barth, A., Bidmon, D., Ponocny, I., Weber, M., Mayr, O., Robertson, D., Diedrich, A., Maier, R., Pilger, A., et al. (2005) · Hypertension · doi:10.1161/01.hyp.0000156540.25707.af · Cited by 156 · see citing works
Sleep Disturbances and Diminished Quality of Life in Postural Tachycardia Syndrome
Bagai, K., Song, Y., Ling, J. F., Malow, B., Black, B. K., Biaggioni, I., Robertson, D., & Raj, S. R. (2011) · Journal of Clinical Sleep Medicine · doi:10.5664/jcsm.28110 · Cited by 134 · see citing works
Psychiatric profile and attention deficits in postural tachycardia syndrome
Raj, V, Haman, K. L., Raj, S. R., Byrne, D., Blakely, R. D., Biaggioni, I., Robertson, D., & Shelton, R. C. (2009) · Journal of Neurology, Neurosurgery & Psychiatry · doi:10.1136/jnnp.2008.144360 · Cited by 131 · see citing works
Hoad, A., Spickett, G., Elliott, J. J., & Newton, J. L. (2008) · QJM · doi:10.1093/qjmed/hcn123 · Cited by 127 · see citing works
Diurnal Patterns of Blood Pressure, Heart Rate and Vasoactive Hormones in Normal Man
Richards, M., Nicholls, M. G., Espiner, E. A., Ikram, H., Cullens, M. M., & Hinton, D. A. (1986) · Clinical and Experimental Hypertension · doi:10.3109/10641968609074769 · Cited by 117 · see citing works
A prospective, 1-year follow-up study of postural tachycardia syndrome
Kimpinski, K., Figueroa, J. J., Singer, W., Sletten, D. M., Iodice, V., Sandroni, P., Fischer, P. R., Opfer-Gehrking, T. L., Gehrking, J. A., & Low, P. A. (2012) · Mayo Clinic Proceedings · doi:10.1016/j.mayocp.2012.02.020 · Cited by 81 · see citing works
Reynolds, G. K., Lewis, D. P., Richardson, A. M., & Lidbury, B. A. (2014) · Journal of Internal Medicine · doi:10.1111/joim.12161 · Cited by 70 · see citing works
Twenty-four-hour urinary sodium excretion and postural orthostatic tachycardia syndrome
Zhang, Q., Liao, Y., Tang, C., Du, J., & Jin, H. (2012) · The Journal of Pediatrics · doi:10.1016/j.jpeds.2012.01.054 · Cited by 66 · see citing works
Zhang, F., Li, X., Ochs, T., Chen, L., Liao, Y., Tang, C., Jin, H., & Du, J. (2012) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2012.04.025 · Cited by 66 · see citing works
Diurnal variability in orthostatic tachycardia: implications for the postural tachycardia syndrome
Brewster, J. A., Garland, E. M., Biaggioni, I., Black, B. K., Ling, J. F., Shibao, C. A., Robertson, D., & Raj, S. R. (2012) · Clinical Science · doi:10.1042/cs20110077 · Cited by 56 · see citing works
Yang, J., Zhao, J., Du, S., Liu, D., Fu, C., Li, X., Chen, S., Tang, C., Du, J., & Jin, H. (2013) · The Journal of Pediatrics · doi:10.1016/j.jpeds.2013.04.039 · Cited by 46 · see citing works
Diagnostic management of orthostatic intolerance in the workplace
Winker, R., Barth, A., Dorner, W., Mayr, O., Pilger, A., Ivancsits, S., Ponocny, I., Heider, A., Wolf, C., & Rüdiger, H. W. (2003) · International Archives of Occupational and Environmental Health · doi:10.1007/s00420-002-0395-4 · Cited by 43 · see citing works
Long-term follow-up of patients with postural tachycardia syndrome
Sousa, A., Lebreiro, A., Freitas, J., & Maciel, M. J. (2012) · Clinical Autonomic Research · doi:10.1007/s10286-011-0155-1 · Cited by 38 · see citing works
Diurnal Heart Rate Patterns in Inappropriate Sinus Tachycardia
RUBENSTEIN, J. C., FREHER, M., KADISH, A., & GOLDBERGER, J. J. (2010) · Pacing and Clinical Electrophysiology · doi:10.1111/j.1540-8159.2010.02725.x · Cited by 23 · see citing works
Postural orthostatic tachycardia syndrome: an underrecognized disorder
Pandian, J. D., Dalton, K., Henderson, R. D., & McCombe, P. (2007) · Internal Medicine Journal · doi:10.1111/j.1445-5994.2007.01356.x · Cited by 17 · see citing works
Moon, J., Lee, H. S., Byun, J.-I., Sunwoo, J.-S., Shin, J.-W., Lim, J.-A., Kim, T.-J., Shin, Y.-W., Lee, K.-J., Jeon, D., et al. (2016) · Journal of the American Society of Hypertension · doi:10.1016/j.jash.2016.01.011 · Cited by 17 · see citing works
Self-citationPrevalence of Postural Orthostatic Tachycardia Syndrome in Patients with Psychiatric Disorders
Lkhagvasuren, B., Oka, T., Kawai, K., Takii, M., Kanemitsu, Y., Tokunaga, S., & Kubo, C. (2011) · Psychotherapy and Psychosomatics · doi:10.1159/000322518 · Cited by 13 · see citing works
Baker, J. R., & Kimpinski, K. (2015) · Physiology & Behavior · doi:10.1016/j.physbeh.2015.04.049 · Cited by 4 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Cognitive and psychological issues in postural tachycardia syndrome
Raj, V., Opie, M., & Arnold, A. C. (2018) · Autonomic Neuroscience · doi:10.1016/j.autneu.2018.03.004 · Cited by 125 · see citing works
Taub, P. R., Zadourian, A., Lo, H. C., Ormiston, C. K., Golshan, S., & Hsu, J. C. (2021) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2020.12.029 · Cited by 122 · see citing works
Postural Orthostatic Tachycardia Syndrome: Prevalence, Pathophysiology, and Management
Zadourian, A., Doherty, T. A., Swiatkiewicz, I., & Taub, P. R. (2018) · Drugs · doi:10.1007/s40265-018-0931-5 · Cited by 90 · see citing works
Seeley, M., Gallagher, C., Ong, E., Langdon, A., Chieng, J., Bailey, D., Page, A. J., Lim, H. S., & Lau, D. H. (2023) · The American Journal of Medicine · doi:10.1016/j.amjmed.2023.06.010 · Cited by 78 · see citing works
Postural orthostatic tachycardia syndrome in children and adolescents
Boris, J. R. (2018) · Autonomic Neuroscience · doi:10.1016/j.autneu.2018.05.004 · Cited by 58 · see citing works
Health-related quality of life and suicide risk in postural tachycardia syndrome
Pederson, C. L., & Brook, J. B. (2017) · Clinical Autonomic Research · doi:10.1007/s10286-017-0399-5 · Cited by 55 · see citing works
Moon, J., Kim, D.-Y., Lee, W.-J., Lee, H. S., Lim, J.-A., Kim, T.-J., Jun, J.-S., Park, B., Byun, J.-I., Sunwoo, J.-S., et al. (2018) · Neurotherapeutics · doi:10.1007/s13311-018-0612-9 · Cited by 40 · see citing works
Self-citationNunes, J. M., Kell, D. B., & Pretorius, E. (2023) · Blood Reviews · doi:10.1016/j.blre.2023.101075 · Cited by 39 · see citing works
Seeley, M., Gallagher, C., Ong, E., Langdon, A., Chieng, J., Bailey, D., Dennis, A., McCaffrey, N., & Lau, D. H. (2023) · Clinical Autonomic Research · doi:10.1007/s10286-023-00955-9 · Cited by 32 · see citing works
Roma, M., Marden, C. L., & Rowe, P. C. (2018) · Fatigue Biomedicine Health & Behavior · doi:10.1080/21641846.2018.1512836 · Cited by 26 · see citing works
Dipaola, F., Barberi, C., Castelnuovo, E., Minonzio, M., Fornerone, R., Shiffer, D., Cairo, B., Zamuner, A. R., Barbic, F., & Furlan, R. (2020) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph17165872 · Cited by 24 · see citing works
Psychological correlates of patients with postural orthostatic tachycardia syndrome (POTS)
Fisher, C. J., Katzan, I., Heinberg, L. J., Schuster, A. T., Thompson, N. R., & Wilson, R. (2020) · Autonomic Neuroscience · doi:10.1016/j.autneu.2020.102690 · Cited by 22 · see citing works
Hockin, B. C. D., Heeney, N. D., Whitehurst, D., & Claydon, V. (2022) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2022.834879 · Cited by 21 · see citing works
Knoop, I., Picariello, F., Jenkinson, E., Gall, N., Chisari, C., & Moss-Morris, R. (2023) · Autonomic Neuroscience · doi:10.1016/j.autneu.2022.103052 · Cited by 21 · see citing works
“Score / 40 OIQ total Number of participants POTS Moon et al., 2016.”
InfluentialPostural Orthostatic Tachycardia Syndrome: A State-of-the-Art Review
Lau, D. H., Fedorowski, A., Raj, S. R., Schild, C., Pace, L., Blitshteyn, S., Raj, V., Boris, J. R., Kavi, L., Seeley, M., et al. (2026) · Heart Lung and Circulation · doi:10.1016/j.hlc.2025.09.004 · Cited by 21 · see citing works
Kim, N., Park, J., Hong, H., Kong, I. D., & Kang, H.-W. (2019) · Quality of Life Research · doi:10.1007/s11136-019-02295-6 · Cited by 20 · see citing works
The incidence of orthostatic intolerance after bariatric surgery
Zhang, J. B., Tamboli, R. A., Albaugh, V. L., Williams, D. B., Kilkelly, D. M., Grijalva, C. G., & Shibao, C. A. (2019) · Obesity Science & Practice · doi:10.1002/osp4.383 · Cited by 20 · see citing works
Eftekhari, H., Maddock, H., Pearce, G., Raza, S., Kavi, L., Lim, P. B., Osman, F., & Hayat, S. (2021) · Autonomic Neuroscience: Basic & Clinical · doi:10.1016/j.autneu.2021.102808 · Cited by 13 · see citing works
Chan, C., Krahe, A., Lee, Y. T., & Nicholson, L. L. (2019) · Clinical Rheumatology · doi:10.1007/s10067-018-4296-7 · Cited by 18 · see citing works
Christopoulos, E. M., Tran, J., Hillebrand, S. L., Lange, P. W., Iseli, R. K., Meskers, C. G. M., & Maier, A. B. (2020) · International Journal of Cardiology Hypertension · doi:10.1016/j.ijchy.2020.100071 · Cited by 18 · see citing works
Sleep disturbance linked to suicidal ideation in postural orthostatic tachycardia syndrome
Pederson, C. L., & Brook, J. B. (2017) · Nature and Science of Sleep · doi:10.2147/nss.s128513 · Cited by 18 · see citing works
Breier, N., Paranjape, S. Y., Scudder, S. K., Mehr, S. E., Diedrich, A., Flynn, C. R., Okamoto, L. E., Hartmann, B., Gasbjerg, L. S., & Shibao, C. A. (2022) · Hypertension · doi:10.1161/hypertensionaha.121.17852 · Cited by 17 · see citing works
Determining autonomic sympathetic tone and reactivity using Baevsky’s stress index
Huizinga, J. D., Chen, J., Hussain, A., Zheng, D., Liu, L., Lui, H., Pan, M., Chen, X., DiBattista, B., Alam, M., et al. (2025) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00243.2024 · Cited by 16 · see citing works
Association of blood pressure variability with orthostatic intolerance symptoms
Sunwoo, J.-S., Yang, T.-W., Kim, D.-Y., Lim, J.-A., Kim, T.-J., Byun, J.-I., Moon, J., Lee, S.-T., Jung, K.-H., Park, K.-I., et al. (2017) · PLOS ONE · doi:10.1371/journal.pone.0179132 · Cited by 16 · see citing works
Self-citationOrthostatic Intolerance in Children With Long COVID Utilizing a 10-Minute Passive Standing Test
Morrow, A. K., Villatoro, C., Kokorelis, C., Rowe, P. C., & Malone, L. A. (2024) · Clinical Pediatrics · doi:10.1177/00099228241272053 · Cited by 13 · see citing works
Rodriguez, B., Hochstrasser, A., Eugster, P. J., Grouzmann, E., Müri, R., & Z'Graggen, W. (2022) · Frontiers in Neuroscience · doi:10.3389/fnins.2022.968725 · Cited by 10 · see citing works
Shigeyasu, Y., Okada, A., Fujii, C., Tanaka, C., Sugihara, A., Horiuchi, M., Yorifuji, T., & Tsukahara, H. (2023) · BioPsychoSocial Medicine · doi:10.1186/s13030-023-00278-1 · Cited by 11 · see citing works
Delayed orthostatic hypotension: Severity of clinical symptoms and response to medical treatment
Byun, J., Moon, J., Kim, D.-Y., Shin, H., Sunwoo, J., Lim, J., Kim, T., Lee, W. J., Lee, H. S., Jun, J., et al. (2018) · Autonomic Neuroscience · doi:10.1016/j.autneu.2018.06.005 · Cited by 11 · see citing works
Self-citationFrye, W. S., King, C. K., Schaefer, M. R., Decker, J. A., & Kuhn, B. (2022) · Clinical Pediatrics · doi:10.1177/00099228221141602 · Cited by 10 · see citing works
Exploring quality of life in postural orthostatic tachycardia syndrome: A conceptual analysis
Frye, W. S., & Greenberg, B. A. (2024) · Autonomic Neuroscience · doi:10.1016/j.autneu.2024.103157 · Cited by 11 · see citing works
Tseng, A. S., Traub, N. A., Harris, L. A., Crowell, M. D., Hoffman‐Snyder, C. R., Goodman, B. P., & DiBaise, J. K. (2018) · Journal of Parenteral and Enteral Nutrition · doi:10.1002/jpen.1493 · Cited by 10 · see citing works
Human leukocyte antigen associations in postural tachycardia syndrome
Shin, Y., Moon, J., Kim, T., Kim, D., Chang, H., Jun, J., Lee, S., Jung, K., Park, K., Jung, K., et al. (2019) · Annals of Clinical and Translational Neurology · doi:10.1002/acn3.766 · Cited by 10 · see citing works
Self-citationEstablishing a consensus on ME/CFS exclusionary illnesses
Jason, L. A., Ravichandran, S., Katz, B. Z., Natelson, B. H., & Bonilla, H. F. (2022) · Fatigue Biomedicine Health & Behavior · doi:10.1080/21641846.2022.2150487 · Cited by 10 · see citing works
Levine, D. F., Work, B. D., McDonald, S., Harty, N., Mabe, C., Powell, A., & Sanford, G. (2021) · Occupational Therapy In Health Care · doi:10.1080/07380577.2021.1975200 · Cited by 7 · see citing works
Wu, S., Morgenstern, A., Rice, T., & Coffey, B. J. (2022) · Journal of Child and Adolescent Psychopharmacology · doi:10.1089/cap.2022.29221.bjc · Cited by 7 · see citing works
Postural Orthostatic Tachycardia Syndrome (POTS): A Frequently Missed Diagnosis
George, A., & Winters, B. A. (2022) · The Journal for Nurse Practitioners · doi:10.1016/j.nurpra.2022.08.022 · Cited by 7 · see citing works
Wheeler, C., Pacheco, J. M., Kim, A., Camacho-Santiago, M., Kalafut, M., Ahern, T. S., White, A. A., Patay, B., & Criado, J. (2022) · Applied Psychophysiology and Biofeedback · doi:10.1007/s10484-022-09536-4 · Cited by 6 · see citing works
Non-Pharmacological and Pharmacological Management of Cardiac Dysautonomia Syndromes
Lakkireddy, D. (2019) · Journal of Atrial Fibrillation · doi:10.4022/jafib.2395 · Cited by 6 · see citing works
Cui, Y., Wang, Y., Liu, P., Wang, Y., Du, J., & Jin, H. (2022) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2022.930994 · Cited by 6 · see citing works
Symptom Score: A New Instrument to Assess Orthostatic Intolerance in Children and Adolescents
Cai, H., Wang, S., Zou, R., Liu, P., Yang, H., Wang, Y., & Wang, C. (2020) · Journal of Child Neurology · doi:10.1177/0883073820936025 · Cited by 6 · see citing works
Eftekhari, H., Pearce, G., Staniszewska, S. H., & Seers, K. (2024) · International Journal of Nursing Studies · doi:10.1016/j.ijnurstu.2024.104986 · Cited by 6 · see citing works
Knoop, I., Jones, A. S. K., Gall, N., Chilcot, J., Pascoe, W., & Moss-Morris, R. (2023) · Autonomic Neuroscience: Basic & Clinical · doi:10.1016/j.autneu.2023.103130 · Cited by 5 · see citing works
Knoop, I., Jones, A. S. K., Gall, N. P., Norton, S., Pascoe, W., & Moss-Morris, R. E. (2024) · Psychosomatic Medicine · doi:10.1097/psy.0000000000001346 · Cited by 4 · see citing works
Psychological and Psychiatric Support; When, Why and What to Do
Opie, M., Raj, V., & Arnold, A. C. (2021) · Postural Tachycardia Syndrome · doi:10.1007/978-3-030-54165-1_40 · Cited by 3 · see citing works
THOMAS, G. K., West, J., Golino, M., Kontos, E., Federmann, E. G., Clark, W., McCarty, J. M., Chelimsky, T. C., VanTassell, B., Toumpourleka, M., et al. (2025) · JACC CardioOncology · doi:10.1016/j.jaccao.2025.05.002 · Cited by 3 · see citing works
Awareness of postural orthostatic tachycardia syndrome is required in adolescent syncope
Kim, D. H., Park, J. Y., Kim, S. Y., Lee, N. M., Yi, D. Y., Yun, S. W., Lim, I. S., & Chae, S. A. (2022) · Medicine · doi:10.1097/md.0000000000031513 · Cited by 3 · see citing works
Self-citationHerrera, A., & Behm, J. (2021) · Occupational Therapy In Health Care · doi:10.1080/07380577.2021.1967548 · Cited by 3 · see citing works
Turner, C., Rhodes, J., Crocker, D., Nedza, K., & May, J. (2020) · Case Studies in Sport and Exercise Psychology · doi:10.1123/cssep.2020-0010 · Cited by 2 · see citing works
Bashir, M., Ahluwalia, H., Khan, T., & Sayeed, S. I. (2021) · Italian Journal of Medicine · doi:10.4081/itjm.2021.1340 · Cited by 2 · see citing works
Clinical Prognostic Factors in Pediatric Patients With Orthostatic Intolerance
Ishitsuka, K., Yamawaki, K., Horikawa, M., Nakadate, H., Nagai, A., & Ishiguro, A. (2020) · Global Pediatric Health · doi:10.1177/2333794x20971980 · Cited by 1 · see citing works
Differential diagnosis and treatment of orthostatic intolerance: a narrative review
Kwon, H., & Kim, H. A. (2026) · Journal of Korean Medical Association · doi:10.5124/jkma.26.0032 · Cited by 1 · see citing works
Vorobyeva, N. M., Вячеславовна, Л. А., Павловна, М. И., Kotovskaya, Y. V., & Ткачева, О. Н. (2023) · Arterial’naya Gipertenziya (Arterial Hypertension) · doi:10.18705/1607-419x-2023-29-3-253-265 · Cited by 1 · see citing works
Liang, H., Chen, L., Chen, L., Fang, J., Yi, Y., Gao, Y., Huang, X., Chen, X., Liu, T., Pan, W., et al. (2025) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2025.1576740 · Cited by 1 · see citing works
Thrysoee, L., Thorup, C. B., Rasmussen, T. B., Borregaard, B., Christensen, A. V., Juel, K., Ekholm, O., Vámosi, M., Banke, A., & Berg, S. K. (2019) · European Journal of Cardiovascular Nursing · doi:10.1177/1474515119888813 · Cited by 1 · see citing works
Shigeyasu, Y., Okada, A., Fujii, C., Tanaka, C., Sugihara, A., Horiuchi, M., Yorifuji, T., & Tsukahara, H. (2022) · Research Square · doi:10.21203/rs.3.rs-1887953/v1 · Cited by 1 · see citing works
Review of postural orthostatic tachycardia syndrome: a predominantly female condition
Eftekhari, H., & Hayat, S. A. (2019) · British Journal of Cardiac Nursing · doi:10.12968/bjca.2019.0090
Exercise in the management of postural orthostatic tachycardia syndrome
Adger, K., & Lynch, H. M. (2020) · Journal of Kinesiology & Wellness · doi:10.56980/jkw.v9i.70
Updates in postural tachycardia syndrome
Moon, J. (2021) · Annals of Clinical Neurophysiology · doi:10.14253/acn.2021.23.1.1
Self-citationLocus Coeruleus Volume is Reduced in Early Parkinson Disease-Related Orthostatic Hypotension.Preprint
Beach, P. A., Kurra, N., Hwang, K., Langley, J. A., Hu, X. P., & Huddleston, D. E. (2021) · Research Square · doi:10.21203/rs.3.rs-936643/v1
Heart rate variability indices in children with syncope due to orthostatic hypotension
Kovalchuk, T. (2022) · Bulletin Of Medical And Biological Research · doi:10.11603/bmbr.2706-6290.2022.1.12671
Conditions Associated with Vestibular Migraine in Pediatric Patients
Jenks, C. M., & Brodsky, J. R. (2025) · Springer eBooks · doi:10.1007/978-981-96-2167-5_7
Yi, H., & Tang, W. (2025) · International Journal of Clinical Practice · doi:10.1155/ijcp/6622089
Rich, E. M., Vas, A., Evetts, C. L., Kaplan-Smith, G., & Goodman, B. P. (2025) · Neurorehabilitation · doi:10.1177/10538135251395291
Frye, W. S., Ward, S. R., & Johnston, J. D. (2026) · Autonomic Neuroscience · doi:10.1016/j.autneu.2026.103445
Tilt Table Testing in Paediatric Orthostatic Intolerance: Is 10 Min Long Enough?
Choi, W., & Yun, S. W. (2026) · Journal of Paediatrics and Child Health · doi:10.1111/jpc.70560
- Authors
- Moon, J., Kim, D.-Y., Byun, J.-I., Sunwoo, J.-S., Lim, J.-A., Kim, T.-J., Shin, J.-W., Lee, W.-J., Lee, H. S., Jun, J.-S., Park, K.-I., Jung, K.-H., Lee, S.-T., Jung, K.-Y., Chu, K., & Lee, S. K.
- Affiliations
- Seoul National University (KR)
- CHA University Bundang Medical Center (KR)
- Seoul National University Hospital (KR)
- Corresponding author
- Lee, Han Sang
- Lee, Soon-Tae
- Chu, Kon
- Lee, Sang Kun
- ORCID
- Venue
- Health and Quality of Life Outcomes
- Published
- 2016-10-12
- Volume
- 14
- Issue
- 1
- Pages
- 144-144
- ISSN
- 1477-7525 (ISSN-L)
- PMC
- PMC5059908
- OpenAlex
- W2530716883
- Cited by
- 66
- References
- 33
- Citations by year
- 2026: 4 · 2025: 6 · 2024: 4 · 2023: 6 · 2022: 14 · 2021: 7 · 2020: 8 · 2019: 6 · 2018: 8 · 2017: 3
- FWCI
- 6.28
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- cc-by
- Locations
- Health and Quality of Life Outcomes (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Funders
- Ministry of Health & Welfare, Republic of Korea (Korean Health Technology R&D Project (HI13C1558))
- Topics
- Health Sciences › Medicine › Surgery › Cardiovascular Syncope and Autonomic Disorders
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Heart Rate Variability and Autonomic Control
- Health Sciences › Medicine › Psychiatry and Mental health › Psychosomatic Disorders and Their Treatments
- Keywords
- postural orthostatic tachycardia syndrome, orthostatic intolerance, depression, quality of life, orthostatic tachycardia, heart rate response to standing, symptom assessment, dizziness, chest discomfort, concentration difficulties, nausea, headache
- MeSH terms
- Adult, Depression, Female, Heart Rate, Humans, Male, Middle Aged, Quality of Life, Surveys and Questionnaires, Orthostatic Intolerance, Postural Orthostatic Tachycardia Syndrome, Republic of Korea
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
