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Mesenchymal stem/stromal cells in cancer therapy
Open accessAbstract
The multipotent mesenchymal stem/stromal cells (MSCs), initially discovered from bone marrow in 1976, have been identified in nearly all tissues of human body now. The multipotency of MSCs allows them to give rise to osteocytes, chondrocytes, adipocytes, and other lineages. Moreover, armed with the immunomodulation capacity and tumor-homing property, MSCs are of special relevance for cell-based therapies in the treatment of cancer. However, hampered by lack of knowledge about the controversial roles that MSC plays in the crosstalk with tumors, limited progress has been made with regard to translational medicine. Therefore, in this review, we discuss the prospects of MSC-associated anticancer strategies in light of therapeutic mechanisms and signal transduction pathways. In addition, the clinical trials designed to appraise the efficacy and safety of MSC-based anticancer therapies will be assessed according to published data.
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“The adaptability of MSCs, although beneficial in regenerative medicine, may elevate the risk of these cells unintentionally developing tumorigenic characteristics in the context of malignancy [300, 301].”
From Mesenchymal stromal cells in bone marrow niche of patients with multiple myeloma: a double-edged sword (2025) · cites this paper as [300]
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“A recent meta-analysis of MSC therapies in oncology revealed that modified MSCs may develop tumorigenic properties under prolonged culture conditions, especially with extensive passaging or exposure to pro-inflammatory cytokines.”
From Mesenchymal stromal cells in bone marrow niche of patients with multiple myeloma: a double-edged sword (2025) · cites this paper as [300]
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“Studies indicate that genetic modifications intended to enhance the regenerative potential of mesenchymal stem cells (MSCs), such as the overexpression of fibroblast growth factor-2 (FGF-2) or hepatocyte growth factor (HGF), may unintentionally promote tumor growth.”
From Mesenchymal stromal cells in bone marrow niche of patients with multiple myeloma: a double-edged sword (2025) · cites this paper as [300]
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“Recent investigations have demonstrated that MSCs possess significant plasticity, enabling them to adapt dynamically to their microenvironment.”
From Mesenchymal stromal cells in bone marrow niche of patients with multiple myeloma: a double-edged sword (2025) · cites this paper as [300]
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“Studies indicate that MSCs derived from MM patients possess genetic mutations that increase their susceptibility to malignant transformation.”
From Mesenchymal stromal cells in bone marrow niche of patients with multiple myeloma: a double-edged sword (2025) · cites this paper as [300]
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Multilineage potential of adult human mesenchymal stem cells
Pittenger, M. F., Mackay, A. M., Beck, S. C., Jaiswal, R. K., Douglas, R., Mosca, J. D., Moorman, M. A., Simonetti, D. W., Craig, S., & Marshak, D. R. (1999) · Science · doi:10.1126/science.284.5411.143 · Cited by 21,052
Siegel, R. L., Miller, K. D., Fuchs, H. E., & Jemal, A. (2021) · CA: A Cancer Journal for Clinicians · doi:10.3322/caac.21654 · Cited by 16,522
Molecular Mechanisms of Stress-Responsive Changes in Collagen and Elastin Networks in Skin
Aziz, J., Shezali, H., Radzi, Z., Yahya, N. A., Abu Kassim, N. H., Czernuszka, J., & Rahman, M. T. (2016) · Skin Pharmacology and Physiology · doi:10.1159/000447017 · Cited by 7,323
Human Adipose Tissue Is a Source of Multipotent Stem Cells
Zuk, P. A., Zhu, M., Ashjian, P. H., Ugarte, D. A. D., Huang, J. I., Mizuno, H., Alfonso, Z. C., Fraser, J. K., Benhaim, P., & Hedrick, M. H. (2002) · Molecular Biology of the Cell · doi:10.1091/mbc.e02-02-0105 · Cited by 6,762
Role of YAP/TAZ in mechanotransduction
Dupont, S., Morsut, L., Aragona, M., Enzo, E., Giulitti, S., Cordenonsi, M., Zanconato, F., Le Digabel, J., Forcato, M., Bicciato, S., et al. (2011) · Nature · doi:10.1038/nature10137 · Cited by 5,979
Stöckl, S., Göttl, C., Grifka, J. K., & Grässel, S. (2013) · Cellular Physiology and Biochemistry · doi:10.1159/000350089 · Cited by 4,670
Tumors: Wounds That Do Not Heal
Flier, J. S., Underhill, L. H., & Dvorak, H. F. (1986) · New England Journal of Medicine · doi:10.1056/nejm198612253152606 · Cited by 4,391 · cited 1×
“The tumor homing property of MSCs Since the development of cancer shares multiple similarities with wound healing, tumors are also known as “wounds that do not heal” [109].”
BackgroundMatrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling
Levental, K. R., Yu, H., Kass, L., Lakins, J. N., Egeblad, M., Erler, J. T., Fong, S. F. T., Csiszar, K., Giaccia, A., Weninger, W., et al. (2009) · Cell · doi:10.1016/j.cell.2009.10.027 · Cited by 4,101
Wnt signalling in stem cells and cancer
Reya, T., & Clevers, H. (2005) · Nature · doi:10.1038/nature03319 · Cited by 3,666
The complexity of NF-κB signaling in inflammation and cancer
Hoesel, B., & Schmid, J. A. (2013) · Molecular Cancer · doi:10.1186/1476-4598-12-86 · Cited by 3,277
Research works printed but not linked: 2
- Khakoo AY, Pati S, Anderson SA, Reid W, Elshal MF, Rovira II, et al. Human mesenchymal stem cells exert potent antitumorigenic effects in a model of Kaposi’s sarcoma. J Exp Med. 2006;203(5):1235–47. · DOI · Paper page
- Wang W, Zhong W, Yuan J, Yan C, Hu S, Tong Y, et al. Involvement of Wnt/β-catenin signaling in the mesenchymal stem cells promote metastatic growth and chemoresistance of cholangiocarcinoma. Oncotarget. 2015;6(39):42276–89. · DOI
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Zhao, K., Lin, R., Fan, Z., Chen, X., Wang, Y., Huang, F., Xu, N., Zhang, X., Zhang, X., Xuan, L., et al. (2022) · Journal of Hematology & Oncology · doi:10.1186/s13045-022-01240-4 · Cited by 89
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Metadata
- Authors
- Lan, T., Luo, M., & Wei, X.
- Affiliations
- Sichuan University (CN)
- Corresponding author
- Luo, Min
- Wei, Xiawei
- ORCID
- Venue
- Journal of Hematology & Oncology
- Published
- 2021-11-17
- Volume
- 14
- Issue
- 1
- Pages
- 195-195
- ISSN
- 1756-8722 (ISSN-L)
- PMC
- PMC8596342
- OpenAlex
- W3211554128
- Cited by
- 374
- References
- 205
- Citations by year
- 2026: 63 · 2025: 105 · 2024: 103 · 2023: 91 · 2022: 12
- FWCI
- 7.34
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- Journal of Hematology & Oncology (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Funders
- National Natural Science Foundation Regional Innovation and Development (U19A2003)
- National Major Scientific and Technological Special Project for “Significant New Drugs Development” (2018ZX09733001)
- Excellent Youth Foundation of the Sichuan Scientific Committee Grant in China (2019JDJQ008)
- Development Program of China (2016YFA0201402)
- National Natural Science Foundation of China (31800773)
- Sichuan Science and Technology Program (2019YJ0063)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Mesenchymal stem cell research
- Health Sciences › Medicine › Oncology › Cancer Cells and Metastasis
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Biotechnology › Bacterial Cancer Therapy
- Keywords
- mesenchymal stem cells, cancer therapy, cell therapy, immunomodulation, tumor homing, signaling pathways, clinical trials, translational medicine
- MeSH terms
- Translational Science, Biomedical, Animals, Humans, Neoplasms, Mesenchymal Stem Cell Transplantation, Immunomodulation, Mesenchymal Stem Cells
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