Student or educator? Sign up with your school email and get 6 months of Pro free.
CoChat
Sign Up
Cited by 83

The DOI matches its Crossref record; 27 of the 27 references it cites were found in a registry or an index.

Epigenetics of prenatal stress in humans: the current research landscape

Dieckmann, Linda, Czamara, Darina·2024·Clinical Epigenetics
DOI 10.1186/s13148-024-01635-9
Open this paper in CoChat — free account

Abstract

Fetal exposure to prenatal stress can have significant consequences on short- and long-term health. Epigenetic mechanisms, especially DNA methylation (DNAm), are a possible process how these adverse environmental events could be biologically embedded. We evaluated candidate gene as well as epigenome-wide association studies associating prenatal stress and DNAm changes in peripheral tissues; however, most of these findings lack robust replication. Prenatal stress-associated epigenetic changes have also been linked to child health including internalizing problems, neurobehavioral outcomes and stress reactivity. Future studies should focus on refined measurement and definition of prenatal stress and its timing, ideally also incorporating genomic as well as longitudinal information. This will provide further opportunities to enhance our understanding of the biological embedding of prenatal stress exposure.

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1186/s13148-024-01635-9

Cites

27 of 27 references verified0 citation errors · 0 not checkable

Statistics

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

Show all 27 references

Research works printed but not linked: 81

  1. Appleton AA, Lester BM, Armstrong DA, Lesseur C, Marsit CJ. Examining the joint contribution of placental NR3C1 and HSD11B2 methylation for infant neurobehavior. Psychoneuroendocrinology. 2015;52:32–42. https://doi.org/10.1016/j.psyneuen.2014.11.004. · DOI
  2. Babenko O, Kovalchuk I, Metz GA. Stress-induced perinatal and transgenerational epigenetic programming of brain development and mental health. Neurosci Biobehav Rev. 2015;48:70–91. https://doi.org/10.1016/j.neubiorev.2014.11.013. · DOI · Paper page
  3. Barker DJ, Forsen T, Uutela A, Osmond C, Eriksson JG. Size at birth and resilience to effects of poor living conditions in adult life: longitudinal study. BMJ. 2001;323(7324):1273–6. https://doi.org/10.1136/bmj.323.7324.1273. · DOI · Paper page
  4. Barouki R, Gluckman PD, Grandjean P, Hanson M, Heindel JJ. Developmental origins of non-communicable disease: implications for research and public health. Environ Health. 2012;11:42. https://doi.org/10.1186/1476-069X-11-42. · DOI
  5. Bogdanovic O, van Heeringen SJ, Veenstra GJ. The epigenome in early vertebrate development. Genesis. 2012;50(3):192–206. https://doi.org/10.1002/dvg.20831. · DOI
  6. Boks MP, Derks EM, Weisenberger DJ, Strengman E, Janson E, Sommer IE, Ophoff RA. The relationship of DNA methylation with age, gender and genotype in twins and healthy controls. PLoS ONE. 2009;4(8): e6767. https://doi.org/10.1371/journal.pone.0006767. · DOI
  7. Bowers ME, Yehuda R. Intergenerational transmission of stress in humans. Neuropsychopharmacology. 2016;41(1):232–44. https://doi.org/10.1038/npp.2015.247. · DOI
  8. Brunst KJ, Tignor N, Just A, Liu Z, Lin X, Hacker MR, Wright RJ. Cumulative lifetime maternal stress and epigenome-wide placental DNA methylation in the PRISM cohort. Epigenetics. 2018;13(6):665–81. https://doi.org/10.1080/15592294.2018.1497387. · DOI
  9. Cao-Lei L, Dancause KN, Elgbeili G, Laplante DP, Szyf M, King S. DNA methylation mediates the effect of maternal cognitive appraisal of a disaster in pregnancy on the child’s C-peptide secretion in adolescence: Project Ice Storm. PLoS ONE. 2018;13(2): e0192199. https://doi.org/10.1371/journal.pone.0192199. · DOI
  10. Cao-Lei L, Dancause KN, Elgbeili G, Massart R, Szyf M, Liu A, King S. DNA methylation mediates the impact of exposure to prenatal maternal stress on BMI and central adiposity in children at age 13(1/2) years: project ice storm. Epigenetics. 2015;10(8):749–61. https://doi.org/10.1080/15592294.2015.1063771. · DOI
  11. Cao-Lei L, de Rooij SR, King S, Matthews SG, Metz GAS, Roseboom TJ, Szyf M. Prenatal stress and epigenetics. Neurosci Biobehav Rev. 2020;117:198–210. https://doi.org/10.1016/j.neubiorev.2017.05.016. · DOI · Paper page
  12. Cecil CA, Lysenko LJ, Jaffee SR, Pingault JB, Smith RG, Relton CL, Barker ED. Environmental risk, oxytocin receptor gene (OXTR) methylation and youth callous-unemotional traits: a 13-year longitudinal study. Mol Psychiatry. 2014;19(10):1071–7. https://doi.org/10.1038/mp.2014.95. · DOI
  13. Cohen S, Kessler RC, Gordon LU. Strategies for measuring stress in studies of psychiatric and physical disorders. In: Cohen S, Kessler RC, Gordon LU, editors. Measuring stress: A guide for health and social scientists. New York: Oxford University Press; 1995. p. 3–26. · DOI
  14. Conradt E, Lester BM, Appleton AA, Armstrong DA, Marsit CJ. The roles of DNA methylation of NR3C1 and 11beta-HSD2 and exposure to maternal mood disorder in utero on newborn neurobehavior. Epigenetics. 2013;8(12):1321–9. https://doi.org/10.4161/epi.26634. · DOI
  15. Coussons-Read ME. Effects of prenatal stress on pregnancy and human development: mechanisms and pathways. Obstet Med. 2013;6(2):52–7. https://doi.org/10.1177/1753495X12473751. · DOI · Paper page
  16. Czamara D, Tissink E, Tuhkanen J, Martins J, Awaloff Y, Drake AJ, Binder EB. Combined effects of genotype and childhood adversity shape variability of DNA methylation across age. Transl Psychiatry. 2021;11(1):88. https://doi.org/10.1038/s41398-020-01147-z. · DOI
  17. De Weerth C. Prenatal stress and the development of psychopathology: Lifestyle behaviors as a fundamental part of the puzzle. Dev Psychopathol. 2018;30(3):1129–44. https://doi.org/10.1017/S0954579418000494. · DOI
  18. DeRijk RH, Schaaf M, de Kloet ER. Glucocorticoid receptor variants: clinical implications. J Steroid Biochem Mol Biol. 2002;81(2):103–22. https://doi.org/10.1016/s0960-0760(02)00062-6. · DOI
  19. Dieckmann L, Lahti-Pulkkinen M, Kvist T, Lahti J, DeWitt PE, Cruceanu C, Czamara D. Characteristics of epigenetic aging across gestational and perinatal tissues. Clin Epigenetics. 2021;13(1):97. https://doi.org/10.1186/s13148-021-01080-y. · DOI
  20. Dong E, Pandey SC. Prenatal stress induced chromatin remodeling and risk of psychopathology in adulthood. Int Rev Neurobiol. 2021;156:185–215. https://doi.org/10.1016/bs.irn.2020.08.004. · DOI
  21. Duthie L, Reynolds RM. Changes in the maternal hypothalamic-pituitary-adrenal axis in pregnancy and postpartum: influences on maternal and fetal outcomes. Neuroendocrinology. 2013;98(2):106–15. https://doi.org/10.1159/000354702. · DOI
  22. Eriksson JG, Forsen T, Tuomilehto J, Winter PD, Osmond C, Barker DJ. Catch-up growth in childhood and death from coronary heart disease: longitudinal study. BMJ. 1999;318(7181):427–31. https://doi.org/10.1136/bmj.318.7181.427. · DOI
  23. Felix JF, Joubert BR, Baccarelli AA, Sharp GC, Almqvist C, Annesi-Maesano I, London SJ. Cohort profile: pregnancy and childhood epigenetics (PACE) consortium. Int J Epidemiol. 2018;47(1):22–23u. https://doi.org/10.1093/ije/dyx190. · DOI
  24. Garnica AD, Chan WY. The role of the placenta in fetal nutrition and growth. J Am Coll Nutr. 1996;15(3):206–22. https://doi.org/10.1080/07315724.1996.10718591. · DOI
  25. Glover V. Prenatal stress and its effects on the fetus and the child: possible underlying biological mechanisms. Adv Neurobiol. 2015;10:269–83. https://doi.org/10.1007/978-1-4939-1372-5_13. · DOI
  26. Goyal D, Limesand SW, Goyal R. Epigenetic responses and the developmental origins of health and disease. J Endocrinol. 2019;242(1):T105–19. https://doi.org/10.1530/JOE-19-0009. · DOI
  27. Haq SU, Bhat UA, Kumar A. Prenatal stress effects on offspring brain and behavior: Mediators, alterations and dysregulated epigenetic mechanisms. J Biosci. 2021;46:1–16. · DOI
  28. Hawkins G, Gullam J, Belluscio L. The effect of a major earthquake experienced during the first trimester of pregnancy on the risk of preterm birth. Aust N Z J Obstet Gynaecol. 2019;59(1):82–8. https://doi.org/10.1111/ajo.12797. · DOI
  29. Heinrichs M, Baumgartner T, Kirschbaum C, Ehlert U. Social support and oxytocin interact to suppress cortisol and subjective responses to psychosocial stress. Biol Psychiatry. 2003;54(12):1389–98. https://doi.org/10.1016/s0006-3223(03)00465-7. · DOI · Paper page
  30. Hill J, Pickles A, Wright N, Braithwaite E, Sharp H. Predictions of children’s emotionality from evolutionary and epigenetic hypotheses. Sci Rep. 2019;9(1):2519. https://doi.org/10.1038/s41598-019-39513-7. · DOI
  31. Hill RA, Gibbons A, Han U, Suwakulsiri W, Taseska A, Hammet F, Sundram S. Maternal SARS-CoV-2 exposure alters infant DNA methylation. Brain Behav Immun Health. 2023;27: 100572. https://doi.org/10.1016/j.bbih.2022.100572. · DOI
  32. Holmes TH, Rahe RH. The Social Readjustment Rating Scale. J Psychosom Res. 1967;11(2):213–8. https://doi.org/10.1016/0022-3999(67)90010-4. · DOI
  33. Horvath S, Raj K. DNA methylation-based biomarkers and the epigenetic clock theory of ageing. Nat Rev Genet. 2018;19(6):371–84. https://doi.org/10.1038/s41576-018-0004-3. · DOI · Paper page
  34. Husquin LT, Rotival M, Fagny M, Quach H, Zidane N, McEwen LM, Quintana-Murci L. Exploring the genetic basis of human population differences in DNA methylation and their causal impact on immune gene regulation. Genome Biol. 2018;19(1):222. https://doi.org/10.1186/s13059-018-1601-3. · DOI
  35. Ketchesin KD, Stinnett GS, Seasholtz AF. Corticotropin-releasing hormone-binding protein and stress: from invertebrates to humans. Stress. 2017;20(5):449–64. https://doi.org/10.1080/10253890.2017.1322575. · DOI
  36. King S, Dancause K, Turcotte-Tremblay AM, Veru F, Laplante DP. Using natural disasters to study the effects of prenatal maternal stress on child health and development. Birth Defects Res C Embryo Today. 2012;96(4):273–88. https://doi.org/10.1002/bdrc.21026. · DOI · Paper page
  37. Klengel T, Mehta D, Anacker C, Rex-Haffner M, Pruessner JC, Pariante CM, Binder EB. Allele-specific FKBP5 DNA demethylation mediates gene-childhood trauma interactions. Nat Neurosci. 2013;16(1):33–41. https://doi.org/10.1038/nn.3275. · DOI · Paper page
  38. Kocher K, Bhattacharya S, Niforatos-Andescavage N, Almalvez M, Henderson D, Vilain E, Delot EC. Genome-wide neonatal epigenetic changes associated with maternal exposure to the COVID-19 pandemic. BMC Med Genomics. 2023;16(1):268. https://doi.org/10.1186/s12920-023-01707-4. · DOI
  39. Lazarus RS. Psychological stress and the coping process. New York: McGraw-Hill; 1966.
  40. Lyon BL. Stress, coping, and health: A conceptual overview (update). In: Rice VH, editor. Handbook of stress, coping, and health: Implications for nursing research, theory, and practict. Sage Publications Inc; 2012. p. 2–20.
  41. Mandy M, Nyirenda M. Developmental Origins of Health and Disease: the relevance to developing nations. Int Health. 2018;10(2):66–70. https://doi.org/10.1093/inthealth/ihy006. · DOI
  42. Marsit CJ, Maccani MA, Padbury JF, Lester BM. Placental 11-beta hydroxysteroid dehydrogenase methylation is associated with newborn growth and a measure of neurobehavioral outcome. PLoS ONE. 2012;7(3): e33794. https://doi.org/10.1371/journal.pone.0033794. · DOI
  43. Masuda M, Holmes TH. Magnitude estimations of social readjustments. J Psychosom Res. 1967;11(2):219–25. https://doi.org/10.1016/0022-3999(67)90011-6. · DOI
  44. Matthews SG, McGowan PO. Developmental programming of the HPA axis and related behaviours: epigenetic mechanisms. J Endocrinol. 2019;242(1):T69–79. https://doi.org/10.1530/JOE-19-0057. · DOI
  45. McGill MG, Pokhvisneva I, Clappison AS, McEwen LM, Beijers R, Tollenaar MS, O’Donnell KJ. Maternal prenatal anxiety and the fetal origins of epigenetic aging. Biol Psychiatry. 2022;91(3):303–12. https://doi.org/10.1016/j.biopsych.2021.07.025. · DOI
  46. McGowan PO, Matthews SG. Prenatal stress, glucocorticoids, and developmental programming of the stress response. Endocrinology. 2018;159(1):69–82. https://doi.org/10.1210/en.2017-00896. · DOI
  47. McKenna BG, Hendrix CL, Brennan PA, Smith AK, Stowe ZN, Newport DJ, Knight AK. Maternal prenatal depression and epigenetic age deceleration: testing potentially confounding effects of prenatal stress and SSRI use. Epigenetics. 2021;16(3):327–37. https://doi.org/10.1080/15592294.2020.1795604. · DOI
  48. Monk C, Spicer J, Champagne FA. Linking prenatal maternal adversity to developmental outcomes in infants: the role of epigenetic pathways. Dev Psychopathol. 2012;24(4):1361–76. https://doi.org/10.1017/S0954579412000764. · DOI
  49. Nazzari S, Grumi S, Mambretti F, Villa M, Giorda R, Provenzi L, MCS Group. Maternal and infant NR3C1 and SLC6A4 epigenetic signatures of the COVID-19 pandemic lockdown: when timing matters. Transl Psychiatry. 2022;12(1):386. https://doi.org/10.1038/s41398-022-02160-0. · DOI
  50. Neumann ID, Wigger A, Torner L, Holsboer F, Landgraf R. Brain oxytocin inhibits basal and stress-induced activity of the hypothalamo-pituitary-adrenal axis in male and female rats: partial action within the paraventricular nucleus. J Neuroendocrinol. 2000;12(3):235–43. https://doi.org/10.1046/j.1365-2826.2000.00442.x. · DOI · Paper page
  51. Nolvi S, Merz EC, Kataja EL, Parsons CE. Prenatal stress and the developing brain: postnatal environments promoting resilience. Biol Psychiatry. 2023;93(10):942–52. https://doi.org/10.1016/j.biopsych.2022.11.023. · DOI
  52. O’Donnell K, O’Connor TG, Glover V. Prenatal stress and neurodevelopment of the child: focus on the HPA axis and role of the placenta. Dev Neurosci. 2009;31(4):285–92. https://doi.org/10.1159/000216539. · DOI
  53. Orr ST, James SA, Casper R. Psychosocial stressors and low birth weight: development of a questionnaire. J Dev Behav Pediatr. 1992;13(5):343–7. · DOI
  54. Osmond C, Barker DJ, Winter PD, Fall CH, Simmonds SJ. Early growth and death from cardiovascular disease in women. BMJ. 1993;307(6918):1519–24. https://doi.org/10.1136/bmj.307.6918.1519. · DOI · Paper page
  55. Palma-Gudiel H, Cordova-Palomera A, Leza JC, Fananas L. Glucocorticoid receptor gene (NR3C1) methylation processes as mediators of early adversity in stress-related disorders causality: a critical review. Neurosci Biobehav Rev. 2015;55:520–35. https://doi.org/10.1016/j.neubiorev.2015.05.016. · DOI · Paper page
  56. Palma-Gudiel H, Eixarch E, Crispi F, Moran S, Zannas AS, Fananas L. Prenatal adverse environment is associated with epigenetic age deceleration at birth and hypomethylation at the hypoxia-responsive EP300 gene. Clin Epigenetics. 2019;11(1):73. https://doi.org/10.1186/s13148-019-0674-5. · DOI
  57. Paquette AG, Lester BM, Koestler DC, Lesseur C, Armstrong DA, Marsit CJ. Placental FKBP5 genetic and epigenetic variation is associated with infant neurobehavioral outcomes in the RICHS cohort. PLoS ONE. 2014;9(8): e104913. https://doi.org/10.1371/journal.pone.0104913. · DOI
  58. Paquette AG, Lester BM, Lesseur C, Armstrong DA, Guerin DJ, Appleton AA, Marsit CJ. Placental epigenetic patterning of glucocorticoid response genes is associated with infant neurodevelopment. Epigenomics. 2015;7(5):767–79. https://doi.org/10.2217/epi.15.28. · DOI
  59. Ryan CP. “Epigenetic clocks”: Theory and applications in human biology. Am J Hum Biol. 2021;33(3): e23488. https://doi.org/10.1002/ajhb.23488. · DOI
  60. Sammallahti S, Cortes Hidalgo AP, Tuominen S, Malmberg A, Mulder RH, Brunst KJ, Lahti J. Maternal anxiety during pregnancy and newborn epigenome-wide DNA methylation. Mol Psychiatry. 2021;26(6):1832–45. https://doi.org/10.1038/s41380-020-00976-0. · DOI
  61. Santarelli S, Zimmermann C, Kalideris G, Lesuis SL, Arloth J, Uribe A, Schmidt MV. An adverse early life environment can enhance stress resilience in adulthood. Psychoneuroendocrinology. 2017;78:213–21. https://doi.org/10.1016/j.psyneuen.2017.01.021. · DOI
  62. Schoenmakers S, Verweij EJJ, Beijers R, Bijma HH, Been JV, Steegers-Theunissen RPM, Steegers EAP. The Impact of Maternal Prenatal Stress Related to the COVID-19 Pandemic during the First 1000 Days: A Historical Perspective. Int J Environ Res Public Health. 2022. https://doi.org/10.3390/ijerph19084710. · DOI
  63. Schoof E, Girstl M, Frobenius W, Kirschbaum M, Repp R, Knerr I, Dotsch J. Course of placental 11beta-hydroxysteroid dehydrogenase type 2 and 15-hydroxyprostaglandin dehydrogenase mRNA expression during human gestation. Eur J Endocrinol. 2001;145(2):187–92. https://doi.org/10.1530/eje.0.1450187. · DOI
  64. Selye H. The stress of life. New York, NY: McGraw-Hill; 1956.
  65. Serpeloni F, Radtke KM, Hecker T, Sill J, Vukojevic V, de Assis SG, Natt D. Does prenatal stress shape postnatal resilience? - an epigenome-wide study on violence and mental health in humans. Front Genet. 2019;10:269. https://doi.org/10.3389/fgene.2019.00269. · DOI · Paper page
  66. Shanthikumar S, Neeland MR, Maksimovic J, Ranganathan SC, Saffery R. DNA methylation biomarkers of future health outcomes in children. Mol Cell Pediatr. 2020;7(1):7. https://doi.org/10.1186/s40348-020-00099-0. · DOI
  67. Sharma R, Frasch MG, Zelgert C, Zimmermann P, Fabre B, Wilson R, Antonelli MC. Maternal-fetal stress and DNA methylation signatures in neonatal saliva: an epigenome-wide association study. Clin Epigenetics. 2022;14(1):87. https://doi.org/10.1186/s13148-022-01310-x. · DOI
  68. Sharp GC, Arathimos R, Reese SE, Page CM, Felix J, Kupers LK, Zuccolo L. Maternal alcohol consumption and offspring DNA methylation: findings from six general population-based birth cohorts. Epigenomics. 2018;10(1):27–42. https://doi.org/10.2217/epi-2017-0095. · DOI
  69. Sharp GC, Salas LA, Monnereau C, Allard C, Yousefi P, Everson TM, Relton CL. Maternal BMI at the start of pregnancy and offspring epigenome-wide DNA methylation: findings from the pregnancy and childhood epigenetics (PACE) consortium. Hum Mol Genet. 2017;26(20):4067–85. https://doi.org/10.1093/hmg/ddx290. · DOI
  70. Suarez A, Lahti J, Czamara D, Lahti-Pulkkinen M, Knight AK, Girchenko P, Raikkonen K. The epigenetic clock at birth: associations with maternal antenatal depression and child psychiatric problems. J Am Acad Child Adolesc Psychiatry. 2018;57(5):321–8. https://doi.org/10.1016/j.jaac.2018.02.011. · DOI
  71. Sutherland S, Brunwasser SM. Sex differences in vulnerability to prenatal stress: a review of the recent literature. Curr Psychiatry Rep. 2018;20(11):102. https://doi.org/10.1007/s11920-018-0961-4. · DOI
  72. Szyf M. The epigenetics of perinatal stress dialogues. Clin Neurosci. 2019;21(4):369–78. https://doi.org/10.31887/DCNS.2019.21.4/mszyf. · DOI
  73. Tobi EW, Slieker RC, Stein AD, Suchiman HE, Slagboom PE, van Zwet EW, Lumey LH. Early gestation as the critical time-window for changes in the prenatal environment to affect the adult human blood methylome. Int J Epidemiol. 2015;44(4):1211–23. https://doi.org/10.1093/ije/dyv043. · DOI
  74. Turecki G, Meaney MJ. Effects of the social environment and stress on glucocorticoid receptor gene methylation: a systematic review. Biol Psychiatry. 2016;79(2):87–96. https://doi.org/10.1016/j.biopsych.2014.11.022. · DOI · Paper page
  75. Urday P, Gayen NeeBetal S, Sequeira Gomes R, Al-Kouatly HB, Solarin K, Chan JS, Aghai ZH. SARS-CoV-2 Covid-19 infection during pregnancy and differential DNA methylation in human cord blood cells from term neonates. Epigenet Insights. 2023;16:25168657231184664. https://doi.org/10.1177/25168657231184665. · DOI
  76. Ursini G, Punzi G, Langworthy BW, Chen Q, Xia K, Cornea EA, Weinberger DR. Placental genomic risk scores and early neurodevelopmental outcomes. Proc Natl Acad Sci U S A. 2021. https://doi.org/10.1073/pnas.2019789118. · DOI
  77. Van den Bergh BRH, van den Heuvel MI, Lahti M, Braeken M, de Rooij SR, Entringer S, Schwab M. Prenatal developmental origins of behavior and mental health: the influence of maternal stress in pregnancy. Neurosci Biobehav Rev. 2020;117:26–64. https://doi.org/10.1016/j.neubiorev.2017.07.003. · DOI · Paper page
  78. Varley KE, Gertz J, Bowling KM, Parker SL, Reddy TE, Pauli-Behn F, Myers RM. Dynamic DNA methylation across diverse human cell lines and tissues. Genome Res. 2013;23(3):555–67. https://doi.org/10.1101/gr.147942.112. · DOI
  79. Weaver IC, Cervoni N, Champagne FA, D’Alessio AC, Sharma S, Seckl JR, Meaney MJ. Epigenetic programming by maternal behavior. Nat Neurosci. 2004;7(8):847–54. https://doi.org/10.1038/nn1276. · DOI · Paper page
  80. Zannas AS, Binder EB. Gene-environment interactions at the FKBP5 locus: sensitive periods, mechanisms and pleiotropism. Genes Brain Behav. 2014;13(1):25–37. https://doi.org/10.1111/gbb.12104. · DOI
  81. Zhang W, Ham J, Li Q, Deyssenroth MA, Lambertini L, Huang Y, Nomura Y. Moderate prenatal stress may buffer the impact of superstorm sandy on placental genes: stress in pregnancy (SIP) study. PLoS ONE. 2020;15(1): e0226605. https://doi.org/10.1371/journal.pone.0226605. · DOI

Cited by

Metadata

Authors
Dieckmann, L., & Czamara, D.
Venue
Clinical Epigenetics
Publisher
Springer Science and Business Media LLC
Published
2024-02-02
Volume
16
Issue
1
ISSN
1868-7083
DOI
10.1186/s13148-024-01635-9
Cited by
83
References
27
Language
en
Licence
Funders
  • Add-on Fellowship of the Joachim Herz Foundation
  • Max Planck Institute of Psychiatry

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.