Advances in mesenchymal stem cell exosomes: a review

Extracellular vesicles: Exosomes, microvesicles, and friends

Raposo, G., & Stoorvogel, W. (2013) · Journal of Cell Biology · doi:10.1083/jcb.201211138 · Cited by 8,099

Ceramide Triggers Budding of Exosome Vesicles into Multivesicular Endosomes

Trajković, K., Hsu, C., Chiantia, S., Rajendran, L., Wenzel, D., Wieland, F., Schwille, P., Brügger, B., & Simons, M. (2008) · Science · doi:10.1126/science.1153124 · Cited by 3,760

Exosomes: Current knowledge of their composition, biological functions, and diagnostic and therapeutic potentials

Vlassov, A. V., Magdaleno, S. M., Setterquist, R. A., & Conrad, R. (2012) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2012.03.017 · Cited by 1,979

Exosome and Exosomal MicroRNA: Trafficking, Sorting, and Function

Zhang, J., Li, S., Li, L., Li, M., Guo, C., Yao, J., & Mi, S. (2015) · Genomics, Proteomics & Bioinformatics · doi:10.1016/j.gpb.2015.02.001 · Cited by 1,901

Biogenesis and secretion of exosomes

Kowal, J., Tkach, M., & Théry, C. (2014) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2014.05.004 · Cited by 1,781

Receptor-mediated endocytosis of transferrin and recycling of the transferrin receptor in rat reticulocytes

Harding, C., Heuser, J., & Stahl, P. (1983) · The Journal of Cell Biology · doi:10.1083/jcb.97.2.329 · Cited by 1,775

Optimized exosome isolation protocol for cell culture supernatant and human plasma

Lobb, R. J., Becker, M., Wen, S., Wong, C. S. F., Wiegmans, A. P., Leimgruber, A., & Möller, A. (2015) · Journal of Extracellular Vesicles · doi:10.3402/jev.v4.27031 · Cited by 1,763

Review of the Isolation, Characterization, Biological Function, and Multifarious Therapeutic Approaches of Exosomes

Gurunathan, S., Kang, M.-H., Jeyaraj, M., Qasim, M., & Kim, J. (2019) · Cells · doi:10.3390/cells8040307 · Cited by 1,160

The impact of disparate isolation methods for extracellular vesicles on downstream RNA profiling

Deun, J. V., Mestdagh, P., Sormunen, R. T., Cocquyt, V., Vermaelen, K., Vandesompele, J., Bracke, M., Wever, O. D., & Hendrix, A. (2014) · Journal of Extracellular Vesicles · doi:10.3402/jev.v3.24858 · Cited by 987

Mesenchymal stromal/stem cell (MSC)-Derived exosomes in clinical trials

Lotfy, A., AboQuella, N. M., & Wang, H. (2023) · Stem Cell Research & Therapy · doi:10.1186/s13287-023-03287-7 · Cited by 482

Clinical application of mesenchymal stem cell in regenerative medicine: a narrative review

Margiana, R., Markov, A. A., Zekiy, A. O., Hamza, M. U., Aldabbagh, K. A. O., Al-Zubaidi, S. H., Hameed, N. M., Ahmad, I., Sivaraman, R., Kzar, H. H., et al. (2022) · Stem Cell Research & Therapy · doi:10.1186/s13287-022-03054-0 · Cited by 443

Hybrid exosomes, exosome-like nanovesicles and engineered exosomes for therapeutic applications

Mondal, J., Pillarisetti, S., Junnuthula, V., Saha, M., Hwang, S. R., Park, I.-K., & Lee, Y.-K. (2023) · Journal of Controlled Release · doi:10.1016/j.jconrel.2022.12.027 · Cited by 416

Mesenchymal stem/stromal cells in cancer therapy

Lan, T., Luo, M., & Wei, X. (2021) · Journal of Hematology & Oncology · doi:10.1186/s13045-021-01208-w · Cited by 374

Mesenchymal stem cells-derived exosomes for drug delivery

Sun, Y., Liu, G., Zhang, K., Cao, Q., Liu, T., & Li, J. (2021) · Stem Cell Research & Therapy · doi:10.1186/s13287-021-02629-7 · Cited by 185

Exosomes: Potential Disease Biomarkers and New Therapeutic Targets

Mosquera-Heredia, M. I., Morales, L. C., Vidal, O. M., Barceló, E., Silvera-Redondo, C. A., Velez, J. I., & Garavito, P. (2021) · Biomedicines · doi:10.3390/biomedicines9081061 · Cited by 173

Bone Marrow Mesenchymal Stem Cell-Derived Extracellular Vesicle Infusion for the Treatment of Respiratory Failure From COVID-19

Lightner, A. L., Sengupta, V., Qian, S., Ransom, J. T., Suzuki, S., Park, D. J., Melson, T. I., Williams, B. P., Walsh, J. J., & Awili, M. (2023) · CHEST Journal · doi:10.1016/j.chest.2023.06.024 · Cited by 166

Oxidative stress-induced apoptosis and autophagy: Balancing the contrary forces in spermatogenesis

Sharma, P., Kaushal, N., Saleth, L. R., Ghavami, S., Dhingra, S., & Kaur, P. (2023) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2023.166742 · Cited by 148

Extracellular Vesicles as an Emerging Treatment Option for Intervertebral Disc Degeneration: Therapeutic Potential, Translational Pathways, and Regulatory Considerations

DiStefano, T. J., Vaso, K., Danias, G., Chionuma, H. N., Weiser, J. R., & Iatridis, J. C. (2021) · Advanced Healthcare Materials · doi:10.1002/adhm.202100596 · Cited by 115

Adipose Mesenchymal Stem Cell Derived Exosomes Promote Keratinocytes and Fibroblasts Embedded in Collagen/Platelet‐Rich Plasma Scaffold and Accelerate Wound Healing

Wang, Y., Zhang, Y., Li, T., Shen, K., Wang, K. J., Tian, C., & Hu, D. (2023) · Advanced Materials · doi:10.1002/adma.202303642 · Cited by 119

The potential use of mesenchymal stem cells-derived exosomes as microRNAs delivery systems in different diseases

Oveili, E., Vafaei, S., Bazavar, H., Eslami, Y., Mamaghanizadeh, E., Yasamineh, S., & Gholizadeh, O. (2023) · Cell Communication and Signaling · doi:10.1186/s12964-022-01017-9 · Cited by 118

Exosome-Based Drug Delivery: A Next-Generation Platform for Cancer, Infection, Neurological and Immunological Diseases, Gene Therapy and Regenerative Medicine

Serrano, D. R., Juste, F., Anaya, B. J., Ramirez, B. I., Sánchez-Guirales, S. A., Moyota, J. M. Q., Hernandez, E. M., Simon, J. A., Trallero, J. M., Serrano, C., et al. (2025) · Pharmaceutics · doi:10.3390/pharmaceutics17101336 · Cited by 133

Exosomes Derived from Human Umbilical Cord Mesenchymal Stem Cells Accelerate Diabetic Wound Healing via Promoting M2 Macrophage Polarization, Angiogenesis, and Collagen Deposition

Teng, L., Maqsood, M., Zhu, M., Zhou, Y., Kang, M., Zhou, J., & Chen, J. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms231810421 · Cited by 112

Applications, challenges and prospects of mesenchymal stem cell exosomes in regenerative medicine

Rezabakhsh, A., Sokullu, E., & Rahbarghazi, R. (2021) · Stem Cell Research & Therapy · doi:10.1186/s13287-021-02596-z · Cited by 109

Advances in Mesenchymal Stem Cell-Derived Exosomes as Drug Delivery Vehicles

Rao, D., Huang, D., Sang, C., Zhong, T., Zhang, Z., & Tang, Z. (2022) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2021.797359 · Cited by 97

Mesenchymal Stem Cell-Derived Exosomes and Intervertebral Disc Regeneration: Review

Bhujel, B., Shin, H., Choi, D.-J., & Han, I. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23137306 · Cited by 101

Adipose-derived mesenchymal stromal cell-derived exosomes promote tendon healing by activating both SMAD1/5/9 and SMAD2/3

Liu, H., Zhang, M., Shi, M., Zhang, T., Lu, W., Yang, S., Cui, Q., & Li, Z. (2021) · Stem Cell Research & Therapy · doi:10.1186/s13287-021-02410-w · Cited by 97

Mesenchymal stem cell-derived extracellular vesicles prevent the development of osteoarthritis via the circHIPK3/miR-124-3p/MYH9 axis

Li, S., Liu, J., Liu, S., Jiao, W., & Wang, X. (2021) · Journal of Nanobiotechnology · doi:10.1186/s12951-021-00940-2 · Cited by 98

Systemic proteomics and miRNA profile analysis of exosomes derived from human pluripotent stem cells

Bi, Y., Qiao, X., Liu, Q., Song, S., Zhu, K., Qiu, X., Zhang, X., jia, C., Wang, H., Yang, Z., et al. (2022) · Stem Cell Research & Therapy · doi:10.1186/s13287-022-03142-1 · Cited by 97

3D-exosomes laden multifunctional hydrogel enhances diabetic wound healing via accelerated angiogenesis

Peng, H., Li, H., Zhang, X., Tang, J., Liang, Y., Qiao, L., Zhu, Y., Hou, M., Wei, S., Zhang, Z., et al. (2023) · Chemical Engineering Journal · doi:10.1016/j.cej.2023.146238 · Cited by 92

Recent Clinical Treatment and Basic Research on the Alveolar Bone

Tsuchida, S., & Nakayama, T. (2023) · Biomedicines · doi:10.3390/biomedicines11030843 · Cited by 87

Engineered exosomes and composite biomaterials for tissue regeneration

Hu, W., Wang, W., Chen, Z., Chen, Y., & Wang, Z. (2024) · Theranostics · doi:10.7150/thno.93088 · Cited by 89

Wharton’s jelly mesenchymal stem cells: a concise review of their secretome and prospective clinical applications

Drobiova, H., Sindhu, S. T. A. K., Ahmad, R., Haddad, D., Al‐Mulla, F., & Madhoun, A. S. A. (2023) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2023.1211217 · Cited by 95

Dental Pulp Stem Cells Derived From Adult Human Third Molar Tooth: A Brief Review

Madhoun, A. S. A., Sindhu, S. T. A. K., Haddad, D., Atari, M., Ahmad, R., & Al‐Mulla, F. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.717624 · Cited by 79

The Therapeutic Potential of Exosomes in Soft Tissue Repair and Regeneration

Wan, R., Hussain, A., Behfar, A., Moran, S. L., & Zhao, C. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23073869 · Cited by 74

Construction of Exosome SORL1 Detection Platform Based on 3D Porous Microfluidic Chip and its Application in Early Diagnosis of Colorectal Cancer

Li, P., Chen, J., Chen, Y., Song, S., Huang, X., Yang, Y., Li, Y., Tong, Y., Yan, X., Li, J., et al. (2023) · Small · doi:10.1002/smll.202207381 · Cited by 66

Exosome therapy in hair regeneration: A literature review of the evidence, challenges, and future opportunities

Kost, Y., Muskat, A., Mhaimeed, N., Nazarian, R. S., & Kobets, K. (2022) · Journal of Cosmetic Dermatology · doi:10.1111/jocd.15008 · Cited by 61

Understanding molecular characteristics of extracellular vesicles derived from different types of mesenchymal stem cells for therapeutic translation

Ding, Z., Greenberg, Z., Serafim, M. F., Ali, S., Jamieson, J. C., Traktuev, D. O., March, K. L., & He, M. (2024) · Extracellular Vesicle · doi:10.1016/j.vesic.2024.100034 · Cited by 64

Umbilical Cord Mesenchymal Stem Cell-Derived Small Extracellular Vesicles Deliver miR-21 to Promote Corneal Epithelial Wound Healing through PTEN/PI3K/Akt Pathway

Liu, X., Li, X., Wu, G., Qi, P., Zhang, Y., Liu, Z., Li, X., Yu, Y., Ye, X., Li, Y., et al. (2022) · Stem Cells International · doi:10.1155/2022/1252557 · Cited by 59

Mesenchymal stromal/stem cells and their exosomes application in the treatment of intervertebral disc disease: A promising frontier

Widjaja, G., Jalil, A. T., Budi, H. S., Abdelbasset, W. K., Efendi, S., Suksatan, W., Rita, R. S., Satria, A. P., Surendar, A., Saleh, M. M., et al. (2022) · International Immunopharmacology · doi:10.1016/j.intimp.2022.108537 · Cited by 55

Exosomes: The Latest in Regenerative Aesthetics

Vyas, K. S., Kaufman, J., Munavalli, G. S., Robertson, K., Behfar, A., & Wyles, S. P. (2023) · Regenerative Medicine · doi:10.2217/rme-2022-0134 · Cited by 57

Exosomes derived from adipose-derived stem cells alleviate cigarette smoke-induced lung inflammation and injury by inhibiting alveolar macrophages pyroptosis

Zhu, Z., Lian, X., Su, X., Wu, W., Zeng, Y., & Chen, X. (2022) · Respiratory Research · doi:10.1186/s12931-022-01926-w · Cited by 51

Intra‐Articular Injection of Nanomaterials for the Treatment of Osteoarthritis: From Lubrication Function Restoration to Cell and Gene Therapy

Yang, Y., & Zhang, H. (2024) · Advanced Functional Materials · doi:10.1002/adfm.202401547 · Cited by 53

Potential of Exosomes as Cell-Free Therapy in Articular Cartilage Regeneration: A Review

Ng, C. Y., Chai, J. Y., Foo, J. B., Yahaya, N. H. M., Yang, Y., Ng, M. H., & Law, J. X. (2021) · International Journal of Nanomedicine · doi:10.2147/ijn.s327059 · Cited by 52

Native and engineered exosomes for inflammatory disease

Ma, X., Liu, B., Fan, L., Liu, Y., Zhao, Y., Ren, T., Li, Y., & Li, Y. (2022) · Nano Research · doi:10.1007/s12274-022-5275-5 · Cited by 52

Low-Intensity Pulsed Ultrasound Enhances the Efficacy of Bone Marrow–Derived MSCs in Osteoarthritis Cartilage Repair by Regulating Autophagy-Mediated Exosome Release

Xia, P., Wang, Q., Song, J., Wang, X., Wang, X., Lin, Q., Cheng, K., Chen, A., & Li, X. (2022) · Cartilage · doi:10.1177/19476035221093060 · Cited by 49

Mesenchymal Stem Cell Therapy in Kidney Diseases: Potential and Challenges

Chen, F., Chen, N., Xia, C., Wang, H., Shao, L., Zhou, C., & Wang, J. (2023) · Cell Transplantation · doi:10.1177/09636897231164251 · Cited by 51

Mesenchymal Stem Cell-Derived Exosomes in Ophthalmology: A Comprehensive Review

Wu, K. Y., Ahmad, H., Lin, G., Carbonneau, M., & Tran, S. D. (2023) · Pharmaceutics · doi:10.3390/pharmaceutics15041167 · Cited by 51

Mechanisms and applications of adipose-derived stem cell-extracellular vesicles in the inflammation of wound healing

Jia, Q., Zhao, H., Wang, Y., Cen, Y., & Zhang, Z. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1214757 · Cited by 49

Stem Cell-Derived Exosomes: A Comprehensive Review of Biomedical Applications, Challenges, and Future Directions

Zhang, J., Tian, X., Li, Y., Fang, C., Yang, F., Dong, L., Shen, Y., Pu, S., Li, J., Chang, D., et al. (2025) · International Journal of Nanomedicine · doi:10.2147/ijn.s527137 · Cited by 60

A New Strategy for the Regulation of Neuroinflammation: Exosomes Derived from Mesenchymal Stem Cells

Ge, Y., Wu, J., Zhang, L., Huang, N., & Luo, Y. (2024) · Cellular and Molecular Neurobiology · doi:10.1007/s10571-024-01460-x · Cited by 48

Targeting Capabilities of Native and Bioengineered Extracellular Vesicles for Drug Delivery

Frolova, L., & Li, I. T. S. (2022) · Bioengineering · doi:10.3390/bioengineering9100496 · Cited by 43

Mesenchymal stem cell exosome therapy: current research status in the treatment of neurodegenerative diseases and the possibility of reversing normal brain aging

Quan, J., Liu, Q., Li, P., Yang, Z., Zhang, Y., Zhao, F., & Zhu, G. (2025) · Stem Cell Research & Therapy · doi:10.1186/s13287-025-04160-5 · Cited by 47

Three-Dimensional Bioprinting of Growth Differentiation Factor 5-Preconditioned Mesenchymal Stem Cell-Derived Exosomes Facilitates Articular Cartilage Endogenous Regeneration

Zheng, Y., Fu, L., Zhang, Z., Wu, J., Yuan, X., Ding, Z., Ning, C., Sui, X., Liu, S., & Guo, Q. (2025) · ACS Nano · doi:10.1021/acsnano.4c13492 · Cited by 42

Deciphering the Heterogeneity Landscape of Mesenchymal Stem/Stromal Cell‐Derived Extracellular Vesicles for Precise Selection in Translational Medicine

Li, Y., Chen, Y.-H., Liu, B., Nie, Q., Li, L., Duan, X., Wu, L., & Chen, G. (2023) · Advanced Healthcare Materials · doi:10.1002/adhm.202202453 · Cited by 42

Global Trends of Exosomes Application in Clinical Trials: A Scoping Review

Rahnama, M., Heidari, M., Poursalehi, Z., & Golchin, A. (2024) · Stem Cell Reviews and Reports · doi:10.1007/s12015-024-10791-7 · Cited by 39

Revolutionizing pressure ulcer regeneration: Unleashing the potential of extracellular matrix-derived temperature-sensitive injectable antioxidant hydrogel for superior stem cell therapy

Tang, J., Zhang, P., Liu, Y., Hou, D., Chen, Y., Cheng, L., Xue, Y., & Liu, J. (2024) · Biomaterials · doi:10.1016/j.biomaterials.2024.122880 · Cited by 40

Mesenchymal Stem Cell-Derived Exosomal microRNAs in Cardiac Regeneration

Bhaskara, M. C., Anjorin, O., & Wang, M. (2023) · Cells · doi:10.3390/cells12242815 · Cited by 40

Current Status and Prospect of Delivery Vehicle Based on Mesenchymal Stem Cell-Derived Exosomes in Liver Diseases

Lu, X., Guo, H., Wei, X., Lu, D., Shu, W., Song, Y., Qiu, N., & Xu, X. (2023) · International Journal of Nanomedicine · doi:10.2147/ijn.s404925 · Cited by 38

Engineered mesenchymal stem cell exosomes loaded with miR-34c-5p selectively promote eradication of acute myeloid leukemia stem cells

Wen, J., Chen, Y., Liao, C., Ma, X., Wang, M., Li, Q., Wang, D., Li, Y., Zhang, X., Li, L., et al. (2023) · Cancer Letters · doi:10.1016/j.canlet.2023.216407 · Cited by 37

Mesenchymal Stromal Cell-Derived Tailored Exosomes Treat Bacteria-Associated Diabetes Foot Ulcers: A Customized Approach From Bench to Bed

Raghav, A., Tripathi, P., Mishra, B. K., Jeong, G., Banday, S., Gautam, K. A., Mateen, Q. N., Singh, P. S., Singh, M. K., Singla, A., et al. (2021) · Frontiers in Microbiology · doi:10.3389/fmicb.2021.712588 · Cited by 37

Exosomes as Novel Diagnostic Biomarkers and Therapeutic Tools in Gliomas

Skouras, P., Gargalionis, A. N., & Piperi, C. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms241210162 · Cited by 37

Exosomes Derived from Human Amniotic Mesenchymal Stem Cells Facilitate Diabetic Wound Healing by Angiogenesis and Enrich Multiple lncRNAs

Fu, S., Zhang, H., Li, X., Zhang, Q., Guo, C., Qiu, K., Feng, J., Liu, X., & Liu, D. (2023) · Tissue Engineering and Regenerative Medicine · doi:10.1007/s13770-022-00513-w · Cited by 35

Mesenchymal Stem/Stromal Cells for Therapeutic Angiogenesis

Yusoff, F. M., & Higashi, Y. (2023) · Cells · doi:10.3390/cells12172162 · Cited by 35

Application of Biomaterials in Diabetic Wound Healing: The Recent Advances and Pathological Aspects

Han, C., Singla, R. K., & Wang, C. (2025) · Pharmaceutics · doi:10.3390/pharmaceutics17101295 · Cited by 40

Polydopamine-coated biomimetic bone scaffolds loaded with exosomes promote osteogenic differentiation of BMSC and bone regeneration

Zhou, Y., Deng, G., She, H., Bai, F., Xiang, B., Zhou, J., & Zhang, S. (2023) · Regenerative Therapy · doi:10.1016/j.reth.2023.03.005 · Cited by 34

Exosomes derived from odontogenic stem cells: Its role in the dentin-pulp complex

Zou, J., Xia, H., Jiang, Q., Su, Z., Wen, S., Liang, Z., Ouyang, Y., Liu, J., Zhang, Z., Chen, D., et al. (2023) · Regenerative Therapy · doi:10.1016/j.reth.2023.05.008 · Cited by 32

Mesenchymal Stem Cell‐Derived Exosomes: A Promising Therapeutic Strategy for Age‐Related Diseases

Wei, B., Wei, M., Huang, H., Fan, T., Zhang, Z., & Song, X. (2024) · Cell Proliferation · doi:10.1111/cpr.13795 · Cited by 39

Nanomaterial for Skeletal Muscle Regeneration

Jeong, G., Castels, H., Kang, I., Aliya, B., & Jang, Y. C. (2022) · Tissue Engineering and Regenerative Medicine · doi:10.1007/s13770-022-00446-4 · Cited by 33

Engineered anti-EGFRvIII targeted exosomes induce apoptosis in glioblastoma multiforme

Rahmani, R., Kiani, J., Tong, W. Y., Soleimani, M., Voelcker, N. H., & Arefian, E. (2022) · Journal of drug targeting · doi:10.1080/1061186x.2022.2152819 · Cited by 36

Localized Administration of Mesenchymal Stem Cell–Derived Exosomes for the Treatment of Refractory Perianal Fistula in Patients With Crohn’s Disease: A Phase II Clinical Trial

Hadizadeh, A., Asbagh, R. A., Heirani‐Tabasi, A., Soleimani, M., Gorovanchi, P., Daryani, N. E., Vahedi, A., Nazari, H., Banikarimi, S. P., Dibavar, M. A., et al. (2024) · Diseases of the Colon & Rectum · doi:10.1097/dcr.0000000000003502 · Cited by 35

Regulating pyroptosis by mesenchymal stem cells and extracellular vesicles: A promising strategy to alleviate intervertebral disc degeneration

Yang, S., Zhang, Y., Peng, Q., Meng, B., Wang, J., Sun, H., Chen, L., Dai, R., & Zhang, L. (2023) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2023.116001 · Cited by 33

Advanced nano delivery system for stem cell therapy for Alzheimer's disease

Pan, Y., Li, L., Cao, N., Liao, J., Chen, H., & Zhang, M. (2024) · Biomaterials · doi:10.1016/j.biomaterials.2024.122852 · Cited by 33

Targeted drug delivery of engineered mesenchymal stem/stromal-cell-derived exosomes in cardiovascular disease: recent trends and future perspectives

Pang, J., Hong, S., Xu, X., Lin, Z., Chen, X.-Y., Chen, J., Mou, X., & Hu, P.-Y. (2024) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2024.1363742 · Cited by 32

Mesenchymal stem cell therapy in diabetic foot ulcer: An updated comprehensive review

Hetta, ‏. F., Elsaghir, A., Sijercic, V. C., Akhtar, M. S., Gad, S. A., Moses, A., Zeleke, M. S., Alanazi, F. E., Ahmed, A. K., & Ramadan, Y. N. (2024) · Health Science Reports · doi:10.1002/hsr2.2036 · Cited by 36

Distinct molecular properties and functions of small EV subpopulations isolated from human umbilical cord MSCs using tangential flow filtration combined with size exclusion chromatography

Liu, W. Y., Wang, X., Chen, Y., Yuan, J., Zhang, H., Jin, X., Jiang, Y., Cao, J., Wang, Z., Yang, S., et al. (2025) · Journal of Extracellular Vesicles · doi:10.1002/jev2.70029 · Cited by 30

Effects of periodontal ligament stem cell‐derived exosomes on osteoblastic proliferation, migration, differentiation, apoptosis, and signaling pathways

Lan, Q., Xiao, X., Bi, X., Gu, Y., & Ai, Y. (2022) · Oral Diseases · doi:10.1111/odi.14375 · Cited by 31

Mesenchymal Stem Cells and MSCs-Derived Extracellular Vesicles in Infectious Diseases: From Basic Research to Clinical Practice

Yudintceva, N. M., Mikhailova, N., Fedorov, V., Samochernykh, K. A., Vinogradova, T. I., Muraviov, A. N., & Shevtsov, M. A. (2022) · Bioengineering · doi:10.3390/bioengineering9110662 · Cited by 30

Extracellular vesicles from iPSC-MSCs alleviate chemotherapy-induced mouse ovarian damage via the ILK-PI3K/AKT pathway

Cao, R., 山东大学生殖医学研究中心(山东大学附属生殖医院), 山. 济. 2., Lv, Y., Lü, G., Liu, H., Wang, W., Tan, C., Su, X., Xiong, Z., Ma, J., et al. (2023) · 动物学研究 · doi:10.24272/j.issn.2095-8137.2022.340 · Cited by 33

Bone marrow mesenchymal stem cell’s exosomes as key nanoparticles in osteogenesis and bone regeneration: specific capacity based on cell type

Farashah, M. S. G., Javadi, M., Mohammadi, A., Rad, J. S., Shakouri, S. K., & Roshangar, L. (2022) · Molecular Biology Reports · doi:10.1007/s11033-022-07807-1 · Cited by 29

Nanomedicine in Neuroprotection, Neuroregeneration, and Blood–Brain Barrier Modulation: A Narrative Review

Kršek, A., Jagodic, A., & Batičić, L. (2024) · Medicina · doi:10.3390/medicina60091384 · Cited by 31

Exosomes in neuron-glia communication: A review on neurodegeneration

Akbari‐Gharalari, N., Khodakarimi, S., Nezhadshahmohammad, F., Karimipour, M., Kalan, A. E., & Wu, J. (2024) · Bioimpacts · doi:10.34172/bi.2023.30153 · Cited by 29

Mesenchymal stem cell-derived extracellular vesicles for human diseases

Zhang, X., Che, X., Zhang, S., Wang, R., Li, M., Jin, Y., Wang, T., & Song, Y. (2024) · Extracellular Vesicles and Circulating Nucleic Acids · doi:10.20517/evcna.2023.47 · Cited by 27

Exploring the Role of Extracellular Vesicles in Skeletal Muscle Regeneration

Porcu, C., Dobrowolny, G., & Scicchitano, B. M. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25115811 · Cited by 31

Plant-derived extracellular nanovesicles: a promising biomedical approach for effective targeting of triple negative breast cancer cells

Cui, L., Perini, G., Augello, A., Palmieri, V., Spirito, M. D., & Papi, M. (2024) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2024.1390708 · Cited by 27

Enhanced Tissue Regeneration Through Immunomodulatory Extracellular Vesicles Encapsulated in Diversified Silk‐Based Injectable Hydrogels

Sun, L., Xiao, M., Chen, L., Ni, L., Chen, X., Zhang, L., Yao, J., Shao, Z., Zhao, B., Chen, X., et al. (2024) · Advanced Healthcare Materials · doi:10.1002/adhm.202401460 · Cited by 27

Exosomes as Promising Therapeutic Tools for Regenerative Endodontic Therapy

Kong, Q., Wang, Y., Jiang, N., Wang, Y., Wang, R., Hu, X., Mao, J., & Shi, X. (2024) · Biomolecules · doi:10.3390/biom14030330 · Cited by 27

Characterization of Rosa damascena Callus-Derived Exosome-like Vesicles and Their Multifunctional Activities in Skin-Related Cellular Models

Cho, B. S., Lee, H. J., Son, B., Lee, E., Moon, S. Y., Shin, E., Lee, J. J., Hur, J. Y., Park, S. K., Park, C., et al. (2026) · International Journal of Molecular Sciences · doi:10.3390/ijms27114938 · Cited by 27

A “cell-free treatment” for tendon injuries: adipose stem cell-derived exosomes

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