An introduction to overviews of reviews: planning a relevant research question and objective for an overview
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BACKGROUND: Overviews of systematic reviews are a relatively new approach to synthesising evidence, and research methods and associated guidance are developing. Within this paper we aim to help readers understand key issues which are essential to consider when taking the first steps in planning an overview. These issues relate to the development of clear, relevant research questions and objectives prior to the development of an overview protocol. METHODS: Initial discussions and key concepts for this paper were formed during a workshop on overview methods at the 2016 UK Cochrane Symposium, at which all members of this author group presented work and contributed to wider discussions. Detailed descriptions of the various key features of overviews and their different objectives were created by the author group based upon current evidence (Higgins J, Green S. Cochrane Handbook Syst Rev Interv. 2011;4:5, Pollock M, et al. Sys Rev. 2016;5:190-205, Pollock A, et al. Cochrane overviews of reviews: exploring the methods and challenges. UK and Ireland: Cochrane Symposium; 2016, Pieper D, et al. Res Syn Meth. 2014;5:187-99, Lunny C, et al. Sys Rev. 2016;5:4-12, Hartling L, et al. Comparing multiple treatments: an introduction to overviews of reviews. In 23rd Cochrane Colloquium; 2015, Hartling L, et al. Plos One. 2012;7:1-8, Ballard M, Montgomery P. Res Syn Meth. 2017;8:92-108) and author experiences conducting overviews. RESULTS: Within this paper we introduce different types of overviews and suggest common research questions addressed by these overviews. We briefly reflect on the key features and objectives of the example overviews discussed. CONCLUSIONS: Clear decisions relating to the research questions and objectives are a fundamental first step during the initial planning stages for an overview. Key stakeholders should be involved at the earliest opportunity to ensure that the planned overview is relevant and meaningful to the potential end users of the overview. Following best practice in common with other forms of systematic evidence synthesis, an overview protocol should be published, ensuring transparency and reducing opportunities for introduction of bias in the conduct of the overview.
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The review followed recommended practice including a published protocol with predefined inclusion criteria, standardised data extraction, description of overlap, estimations of common effect sizes where applicable, and assessments of study quality and heterogeneity.
“We also followed recommended practice which include the following features: a published protocol with predefined inclusion criteria; a standardised data extraction technique; a description of any overlap in meta-analyses of the same outcomes; estimations of common effect sizes where applicable; and assessments of study quality and heterogeneity (Aromataris et al., 2015; Fusar-Poli and Radua, 2018;”
From The benefits and harms of community treatment orders for people diagnosed with psychiatric illnesses: A rapid umbrella review of systematic reviews and meta-analyses (2024) · cites this paper as Hunt et al., 2018
The Results and Discussion section (page not available) says an overview’s scope is defined by previously stated inclusion and exclusion criteria and that plans for data analysis should be specified. It also discusses heterogeneity as a challenge. It does not recommend the full listed set of practices, including a published protocol, standardised extraction, descriptions of overlap, common effect-size estimates, or quality assessments. (LLM, conf=0.84)
Experimental — accuracy not yet measuredThe quality of selected studies was assessed using the CASP Systematic Review Checklist.
“The quality of the selected studies was assessed using the Critical Appraisal Skills Program (CASP) for review articles (CASP Systematic Review Checklist). 21”
From Artificial Intelligence and Decision-Making in Healthcare: A Thematic Analysis of a Systematic Review of Reviews (2024) · cites this paper as [21]
The supplied passages are from the References section, and searches of the paper's full-text copy for CASP, the Systematic Review Checklist, and quality assessment of selected reviews found no passage addressing this claim. The copy therefore does not establish that the selected studies were assessed using CASP. (LLM, conf=0.74)
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“…data extraction technique; a description of any overlap in meta-analyses of the same outcomes; estimations of common effect sizes where applicable; and assessments of study quality and heterogeneity (Aromataris et al., 2015; Fusar-Poli and Radua, 2018; Hunt et al., 2018; Pollock et al., 2019).”
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- Authors
- Hunt, H., Pollock, A., Campbell, P., Estcourt, L., & Brunton, G.
- Affiliations
- University of Exeter (GB)
- Glasgow Caledonian University (GB)
- John Radcliffe Hospital (GB)
- University College London (GB)
- Corresponding author
- Hunt, Harriet
- Venue
- Systematic Reviews
- Published
- 2018-03-01
- Volume
- 7
- Issue
- 1
- Pages
- 39-39
- ISSN
- 2046-4053 (ISSN-L)
- PMC
- PMC5831229
- OpenAlex
- W2792896018
- Cited by
- 314
- References
- 40
- Citations by year
- 2026: 15 · 2025: 27 · 2024: 44 · 2023: 63 · 2022: 44 · 2021: 52 · 2020: 45 · 2019: 17 · 2018: 5 · 2013: 1
- FWCI
- 22.69
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- cc-by
- Locations
- Systematic Reviews (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- ResearchOnline (Glasgow Caledonian University) (acceptedVersion, cc-by)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Figshare (submittedVersion)
- Open Research Exeter (University of Exeter) (submittedVersion, cc-by)
- Funders
- NIHR PenCLAHRC
- Topics
- Social Sciences › Decision Sciences › Statistics, Probability and Uncertainty › Meta-analysis and systematic reviews
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Clinical practice guidelines implementation
- Social Sciences › Sociology and Political Science › Delphi Technique in Research
- Keywords
- overviews of reviews, research question formulation, stakeholder engagement, transparency, bias mitigation
- MeSH terms
- Systematic Reviews as Topic, Humans, Research Design
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