Walking improves sleep in individuals with cancer: a meta-analysis of randomized, controlled trials

Chiu, Hsiao-Yean; Huang, Hui-Chuan; Chen, Pin-Yuan; Hou, Wen-Hsuan; Tsai, Pei-Shan

doi:10.1188/15.onf.e54-e62

Cited by 63Cancer survivorship and careSleep and related disordersIntensive Care Unit Cognitive Disorders

Walking improves sleep in individuals with cancer: a meta-analysis of randomized, controlled trials

Chiu, Hsiao-Yean, Huang, Hui-Chuan, Chen, Pin-Yuan, Hou, Wen-Hsuan, Tsai, Pei-Shan·2015·Oncology Nursing Forum

DOI 10.1188/15.onf.e54-e62

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Abstract

PURPOSE/OBJECTIVES: To evaluate the effectiveness of walking exercise on sleep in people with cancer. DATA SOURCES: Databases searched included China Knowledge Resource Integrated Database, CINAHL®, Cochrane Central Register of Controlled Trials, EMBASE, PsycINFO®, PubMed, Wanfang Data, and Web of Science. DATA SYNTHESIS: Nine randomized, controlled trials involving 599 patients were included. Most of the studies used moderate-intensity walking exercise. Overall, walking exercise significantly improved sleep in people with cancer (Hedges' g = –0.52). Moderator analyses showed that walking exercise alone and walking exercise combined with other forms of interventions yielded comparable effects on sleep improvement, and that the effect size did not differ among participants who were at different stages of cancer. The effect sizes for studies involving individuals with breast cancer and for studies including individuals with other types of cancer were similar. CONCLUSIONS: Moderate-intensity walking exercise is effective in improving sleep in individuals with cancer. IMPLICATIONS FOR NURSING: The authors' findings support the inclusion of walking exercise into the multimodal approaches to managing sleep in people with cancer. Healthcare providers must convey the benefits of walking exercise to individuals with cancer who are suffering from sleep problems.

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RCTs designed with bone health as the primary outcome are largely consistent with the ACSM Position Stand for exercise and bone health.
“Two recent systematic reviews in cancer survivors concluded that across all trials the evidence for exercise to improve bone health is inconsistent(45, 46), though RCTs that were designed with bone health as the primary outcome were largely consistent with the exercise recommendations in the ACSM Position Stand for exercise and bone health(47).”
From Exercise Guidelines for Cancer Survivors: Consensus Statement from International Multidisciplinary Roundtable (2019) · cites this paper as [47]
Previous analyses on aerobic exercise included individuals who were healthy, had sleep problems, or had cancer.
“Previous analyses on aerobic exercise included individuals who were healthy, had sleep problems, or had cancer [45,82,83].”
From The effects of exercise on sleep in unipolar depression: a systematic review and network meta-analysis (2021) · cites this paper as [83]

Yaşlı Kadınlarda Üreme Sağlığı
Kokanalı, D., & Engin Üstün, Y. (n.d.) · DergiPark (Istanbul University) · Cited by 170,090 · see citing works
Measuring inconsistency in meta-analyses
Higgins, J. P. T., Thompson, S. G., Deeks, J. J., & Altman, D. G. (2003) · BMJ · doi:10.1136/bmj.327.7414.557 · Cited by 63,139 · see citing works
Bias in meta-analysis detected by a simple, graphical test
Egger, M., Smith, G. D., Schneider, M., & Minder, C. (1997) · BMJ · doi:10.1136/bmj.315.7109.629 · Cited by 56,722 · see citing works
Preferred reporting items for systematic reviews and meta-analyses: the PRISMA Statement.
(2009) · PubMed Central · Cited by 44,859 · see citing works
Meta-analysis in clinical trials
DerSimonian, R., & Laird, N. (1986) · Controlled Clinical Trials · doi:10.1016/0197-2456(86)90046-2 · Cited by 39,552 · see citing works
Preferred reporting items for systematic reviews and meta-analyses: The PRISMA statement
Moher, D., Liberati, A., Tetzlaff, J., Altman, D. G., & the PRISMA Group* (2009) · Annals of Internal Medicine · doi:10.7326/0003-4819-151-4-200908180-00135 · Cited by 37,554 · see citing works
The Pittsburgh Sleep Quality Index: a new instrument for psychiatric practice and research
Buysse, D. J., Reynolds, C. F., Monk, T. H., Berman, S. R., & Kupfer, D. J. (1989) · Psychiatry Research · doi:10.1016/0165-1781(89)90047-4 · Cited by 35,234 · see citing works
Operating characteristics of a rank correlation test for publication bias
Begg, C. B., & Mazumdar, M. (1994) · Biometrics · doi:10.2307/2533446 · Cited by 16,955 · see citing works
Trim and Fill: A Simple Funnel‐Plot–Based Method of Testing and Adjusting for Publication Bias in Meta‐Analysis
Duval, S., & Tweedie, R. (2000) · Biometrics · doi:10.1111/j.0006-341x.2000.00455.x · Cited by 14,099 · see citing works
Untitled work
Hao (2015) · doi:10.1002/14651858 · Cited by 11,321 · see citing works
Untitled work
(2000) · Cited by 9,198 · see citing works
A critical review of visual analogue scales in the measurement of clinical phenomena
Wewers, M. E., & Lowe, N. K. (1990) · Research in Nursing & Health · doi:10.1002/nur.4770130405 · Cited by 2,580 · see citing works
Physical Activity and Mental Health: Current Concepts
Paluska, S. A., & Schwenk, T. L. (2000) · Sports Medicine · doi:10.2165/00007256-200029030-00003 · Cited by 1,722 · see citing works
Sleep and immune function
Besedovsky, L., Lange, T., & Born, J. (2012) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/s00424-011-1044-0 · Cited by 1,153 · see citing works
Exercise interventions on health-related quality of life for cancer survivors
Mishra, S. I., Scherer, R. W., Geigle, P. M., Berlanstein, D. R., Topaloglu, Ö., Gotay, C. C., & Snyder, C. F. (2012) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd007566.pub2 · Cited by 857 · see citing works
Exercise and sleep
Driver, H. S., & Taylor, S. R. (2000) · Sleep Medicine Reviews · doi:10.1053/smrv.2000.0110 · Cited by 769 · see citing works
Sleep disturbance in cancer patients
Davidson, J. R., MacLean, A., Brundage, M., & Schulze, K. M. (2002) · Social Science & Medicine · doi:10.1016/s0277-9536(01)00043-0 · Cited by 663 · see citing works
Effects of exercise on fatigue, physical functioning, and emotional distress during radiation therapy for breast cancer.
Mock, V., Dow, K. H., Meares, C. J., Grimm, P. M., Dienemann, J. A., Haisfield‐Wolfe, M. E., Quitasol, W., Mitchell, S., Chakravarthy, A. B., & Gage, I. (1997) · PubMed · Cited by 597 · see citing works
Randomized Study on the Efficacy of Cognitive-Behavioral Therapy for Insomnia Secondary to Breast Cancer, Part I: Sleep and Psychological Effects
Savard, J., Simard, S., Ivers, H., & Morin, C. M. (2005) · Journal of Clinical Oncology · doi:10.1200/jco.2005.09.548 · Cited by 507 · see citing works
Validation of the EORTC QLQ-C30 quality of life questionnaire through combined qualitative and quantitative assessment of patient-observer agreement
Grøenvold, M., Klee, M., Sprangers, M. A. G., & Aaronson, N. K. (1997) · Journal of Clinical Epidemiology · doi:10.1016/s0895-4356(96)00428-3 · Cited by 485 · see citing works
Validity of a verbally administered numeric rating scale to measure cancer pain intensity
Paice, J. A., & Cohen, F. L. (1997) · Cancer Nursing · doi:10.1097/00002820-199704000-00002 · Cited by 434 · see citing works
Effects of Exercise on Heart Rate Variability: Inferences from Meta-Analysis
SANDERCOCK, G. R. H., Bromley, P. D., & Brodie, D. A. (2005) · Medicine & Science in Sports & Exercise · doi:10.1249/01.mss.0000155388.39002.9d · Cited by 392 · see citing works
Randomized controlled clinical effectiveness trial of cognitive behavior therapy compared with treatment as usual for persistent insomnia in patients with cancer
Espie, C. A., Fleming, L., Cassidy, J., Samuel, L., Taylor, L. M., White, C. A., Douglas, N. J., Engleman, H. M., Kelly, H.-L., & Paul, J. (2008) · Journal of Clinical Oncology · doi:10.1200/jco.2007.13.9006 · Cited by 383 · see citing works
A Home-Based Exercise Program to Improve Function, Fatigue, and Sleep Quality in Patients With Stage IV Lung and Colorectal Cancer: A Randomized Controlled Trial
Cheville, A. L., Kollasch, J., Vandenberg, J., Shen, T., Grothey, A., Gamble, G., & Basford, J. R. (2013) · Journal of Pain and Symptom Management · doi:10.1016/j.jpainsymman.2012.05.006 · Cited by 299 · see citing works
Effects of a partly self-administered exercise program before, during, and after allogeneic stem cell transplantation
Wiskemann, J., Dreger, P., Schwerdtfeger, R., Bondong, A., Huber, G., Kleindienst, N., Ulrich, C. M., & Bohus, M. (2010) · Blood · doi:10.1182/blood-2010-09-306308 · Cited by 280 · see citing works
Effect of Exercise on Biomarkers, Fatigue, Sleep Disturbances, and Depressive Symptoms in Older Women With Breast Cancer Receiving Hormonal Therapy
Payne, J. K., Held, J., Thorpe, J., & Shaw, H. (2008) · Oncology nursing forum · doi:10.1188/08.onf.635-642 · Cited by 228 · see citing works
Exercise interventions on health‐related quality of life for people with cancer during active treatment
Mishra, S. I., Scherer, R. W., Snyder, C. F., Geigle, P. M., Berlanstein, D. R., & Topaloglu, Ö. (2012) · Clinical Otolaryngology · doi:10.1111/coa.12015 · Cited by 206 · see citing works
Sleep Disturbances in Women With Metastatic Breast Cancer
Koopman, C., Nouriani, B., Erickson, V., Anupindi, R., Butler, L. D., Bachmann, M. H., Sephton, S. E., & Spiegel, D. (2002) · The Breast Journal · doi:10.1046/j.1524-4741.2002.08606.x · Cited by 156 · see citing works
Bidirectional Communication between the Brain and the Immune System: Implications for Physiological Sleep and Disorders with Disrupted Sleep
Lorton, D., Lubahn, C. L., Estus, C., Millar, B. A., Carter, J. L., Wood, C. A., & Bellinger, D. L. (2006) · NeuroImmunoModulation · doi:10.1159/000104864 · Cited by 147 · see citing works
The Effect of Yoga Exercise on Improving Depression, Anxiety, and Fatigue in Women With Breast Cancer
Taso, C.-J., Lin, H., Lin, W.-L., Chen, S.-M., Huang, W., & Chen, S.-W. (2014) · Journal of Nursing Research · doi:10.1097/jnr.0000000000000044 · Cited by 147 · see citing works
Chronic hypnotic use: deadly risks, doubtful benefit
Kripke, D. F. (2000) · Sleep Medicine Reviews · doi:10.1053/smrv.1999.0076 · Cited by 147 · see citing works
A randomised controlled trial testing the feasibility and efficacy of a physical activity behavioural change intervention in managing fatigue with gynaecological cancer survivors
Donnelly, C., Blaney, J., Lowe-Strong, A., Rankin, J. P., Campbell, A., McCrum-Gardner, E., & Gracey, J. (2011) · Gynecologic Oncology · doi:10.1016/j.ygyno.2011.05.029 · Cited by 132 · see citing works
Physical Activity and Health Outcomes Three Months After Completing a Physical Activity Behavior Change Intervention: Persistent and Delayed Effects
Rogers, L. Q., Hopkins-Price, P. L., Vicari, S., Markwell, S. J., Pamenter, R. W., Courneya, K. S., Hoelzer, K. L., Naritoku, C., Edson, B., Jones, L., et al. (2009) · Cancer Epidemiology Biomarkers & Prevention · doi:10.1158/1055-9965.epi-08-1045 · Cited by 127 · see citing works
Effects of a 6-Week Walking Program on Taiwanese Women Newly Diagnosed With Early-Stage Breast Cancer
Wang, Y., Boehmke, M. M., Wu, Y. B., Dickerson, S. S., & Fisher, N. M. (2010) · Cancer Nursing · doi:10.1097/ncc.0b013e3181e4588d · Cited by 117 · see citing works
Sleep disorders in advanced cancer patients: prevalence and factors associated
Mercadante, S., Girelli, D., & Casuccio, A. (2004) · Supportive Care in Cancer · doi:10.1007/s00520-004-0623-4 · Cited by 115 · see citing works
Sleep-Wake Disturbances in People With Cancer Part I: An Overview of Sleep, Sleep Regulation, and Effects of Disease and Treatment
Vena, C. I., Parker, K. P., Cunningham, M., Clark, J. R., & McMillan, S. (2004) · Oncology nursing forum · doi:10.1188/04.onf.735-746 · Cited by 114 · see citing works
Exercise, sleep quality, and mediators of sleep in breast and prostate cancer patients receiving radiation therapy
Sprod, L. K., Palesh, O. G., Janelsins, M. C., Peppone, L. J., Heckler, C. E., Adams, M. J., Morrow, G. R., & Mustian, K. M. (2010) · Community Oncology · doi:10.1016/s1548-5315(11)70427-2 · Cited by 102 · see citing works
Improving sleep quality for cancer patients: benefits of a home-based exercise intervention
Tang, M.-F., Liou, T., & Lin, C. (2009) · Supportive Care in Cancer · doi:10.1007/s00520-009-0757-5 · Cited by 102 · see citing works
Effects of Exercise on Fatigue, Sleep, and Performance: A Randomized Trial
Coleman, E. A., Goodwin, J. A., Kennedy, R., Coon, S. K., Richards, K. C., Enderlin, C. A., Stewart, C. B., McNatt, P., Lockhart, K., & Anaissie, E. J. (2012) · Oncology nursing forum · doi:10.1188/12.onf.468-477 · Cited by 97 · see citing works
Sleep and circadian rhythm regulate circulating complement factors and immunoregulatory properties of C5a
Reis, E. S., Lange, T., Köhl, G., Herrmann, A., Tschulakow, A., Naujoks, J., Jan Born, A., & Köhl, J. (2011) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2011.04.011 · Cited by 95 · see citing works
Brain temperature and exercise performance
Nybo, L. (2011) · Experimental Physiology · doi:10.1113/expphysiol.2011.062273 · Cited by 86 · see citing works
Sleep disturbances in palliative cancer patients attending a pain and symptom control clinic
Sela, R. A., Watanabe, S., & Nekolaichuk, C. (2005) · Palliative & Supportive Care · doi:10.1017/s1478951505050042 · Cited by 84 · see citing works
Impact of a Home-Based Walking Intervention on Outcomes of Sleep Quality, Emotional Distress, and Fatigue in Patients Undergoing Treatment for Solid Tumors
Wenzel, J. A., Griffith, K. A., Shang, J., Thompson, C. B., Hedlin, H., Stewart, K. J., DeWeese, T., & Mock, V. (2013) · The Oncologist · doi:10.1634/theoncologist.2012-0278 · Cited by 70 · see citing works
Sleep disturbances and impaired daytime functioning in outpatients with newly diagnosed lung cancer
Guen, Y. L., Gagnadoux, F., Hureaux, J., Jeanfaivre, T., Meslier, N., Racineux, J.-L., & Urban, T. (2007) · Lung Cancer · doi:10.1016/j.lungcan.2007.05.021 · Cited by 69 · see citing works
Inflammation and psychosocial factors mediate exercise effects on sleep quality in breast cancer survivors: pilot randomized controlled trial
Rogers, L. Q., Fogleman, A. J., Trammell, R. A., Hopkins-Price, P. L., Spenner, A., Vicari, S. K., Rao, K., Courneya, K. S., Hoelzer, K. L., ROBBS, R. S., et al. (2014) · Psycho-Oncology · doi:10.1002/pon.3594 · Cited by 67 · see citing works
Validation and Comparison of the Health-Related Quality-of-Life Instruments EORTC QLQ-C30 and SF-36 in Assessment of Patients with Chronic Nonmalignant Pain
Fredheim, O. M. S., Borchgrevink, P. C., Saltnes, T., & Kaasa, S. (2007) · Journal of Pain and Symptom Management · doi:10.1016/j.jpainsymman.2007.01.011 · Cited by 63 · see citing works
Association between the increase in brain temperature and physical performance at different exercise intensities and protocols in a temperate environment
Kunstetter, A. C., Wanner, S. P., Madeira, L. G., Wilke, C. F., Rodrigues, L. O. C., & Lima, N. R. V. (2014) · Brazilian Journal of Medical and Biological Research · doi:10.1590/1414-431x20143561 · Cited by 35 · see citing works
Patients attitudes towards sleep disturbances during chemotherapy
Romito, F., Cormio, C., Padova, S. D., Lorusso, V., Berio, M. A., Fimiani, F., Piattelli, A., Palazzo, S., Abram, G., Dudine, L., et al. (2013) · European Journal of Cancer Care · doi:10.1111/ecc.12106 · Cited by 30 · see citing works
Management of insomnia: update and new approaches
Riemann, D. W. (2010) · Nature and Science of Sleep · doi:10.2147/nss.s6642 · Cited by 23 · see citing works

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Exercise Guidelines for Cancer Survivors: Consensus Statement from International Multidisciplinary Roundtable
CAMPBELL, K. L., WINTERS-STONE, K. M., WISKEMANN, J., MAY, A. M., SCHWARTZ, A. L., COURNEYA, K. S., ZUCKER, D. S., MATTHEWS, C. E., LIGIBEL, J. A., GERBER, L. H., et al. (2019) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0000000000002116 · Cited by 2,988 · see citing works
“Two recent systematic reviews in cancer survivors (49,50) provided mixed evidence for overall sleep quality, indicating either a positive effect of walking (49) or no effect of exercise (50).”
Background
The Impact of Exercise on Cancer Mortality, Recurrence, and Treatment-Related Adverse Effects
Cormie, P., Zopf, E. M., Zhang, X., & Schmitz, K. H. (2017) · Epidemiologic Reviews · doi:10.1093/epirev/mxx007 · Cited by 691 · see citing works
Physical activity for women with breast cancer after adjuvant therapy
Lahart, I. M., Metsios, G. S., Nevill, A. M., & Carmichael, A. R. (2018) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd011292.pub2 · Cited by 284 · see citing works
Walkability and Its Relationships With Health, Sustainability, and Livability: Elements of Physical Environment and Evaluation Frameworks
Baobeid, A., Koç‬, M., & Al‐Ghamdi, S. G. (2021) · Frontiers in Built Environment · doi:10.3389/fbuil.2021.721218 · Cited by 279 · see citing works
“Moderate walking additionally has been discovered to help cancer patients sleep (Chiu et al., 2015).”
Background
Exercise and sleep: a systematic review of previous meta‐analyses
Kelley, G. A., & Kelley, K. S. (2017) · Journal of Evidence-Based Medicine · doi:10.1111/jebm.12236 · Cited by 258 · see citing works
Sleep and physical activity in university students: A systematic review and meta-analysis
Memon, A. R., Gupta, C. C., Crowther, M. E., Ferguson, S. A., Tuckwell, G. A., & Vincent, G. E. (2021) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2021.101482 · Cited by 180 · see citing works
Walk to a better night of sleep: testing the relationship between physical activity and sleep
Bisson, A., Robinson, S. A., & Lachman, M. E. (2019) · Sleep Health · doi:10.1016/j.sleh.2019.06.003 · Cited by 149 · see citing works
Effects of Aerobic and Resistance Exercises on Physical Symptoms in Cancer Patients: A Meta-analysis
Nakano, J., Hashizume, K., Fukushima, T., Ueno, K., Matsuura, E., Ikio, Y., Ishii, S., Morishita, S., Tanaka, K., & Kusuba, Y. (2018) · Integrative Cancer Therapies · doi:10.1177/1534735418807555 · Cited by 137 · see citing works
Impact of physical exercise in cancer survivors during and after antineoplastic treatments
Ferioli, M., Zauli, G., Martelli, A. M., Vitale, M., McCubrey, J. A., Ultimo, S., Capitani, S., & Neri, L. M. (2018) · Oncotarget · doi:10.18632/oncotarget.24456 · Cited by 120 · see citing works
“A recent meta-analysis concludes that walking is an exercise effectively improving sleep and suggests that walking exercise program should be included in a multimodal approach to manage sleep disorders in people with cancer (Table 2) [181].”
Background
Exercise interventions to improve sleep in cancer patients: a systematic review and meta-analysis
Mercier, J., Savard, J., & Bernard, P. (2017) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2016.11.001 · Cited by 103 · see citing works
Effectiveness of Aerobic Exercise and Tai Chi Interventions on Sleep Quality in Patients With Advanced Lung Cancer
Takemura, N., Cheung, D. S. T., Fong, D., Lee, A. W. M., Lam, T.-C., Ho, J., Kam, T. Y., Chik, J. Y. K., & Lin, C. (2023) · JAMA Oncology · doi:10.1001/jamaoncol.2023.5248 · Cited by 93 · see citing works
Exercise Training for Improving Patient-Reported Outcomes in Patients With Advanced-Stage Cancer: A Systematic Review and Meta-Analysis
Chen, Y.-J., Li, X., Ma, H.-K., Zhang, X., Wang, B.-W., Guo, T.-T., Xiao, Y., Bing, Z., Ge, L., Yang, K., et al. (2019) · Journal of Pain and Symptom Management · doi:10.1016/j.jpainsymman.2019.09.010 · Cited by 89 · see citing works
Effectiveness of aerobic exercise and mind-body exercise in cancer patients with poor sleep quality: A systematic review and meta-analysis of randomized controlled trials
Takemura, N., Cheung, D. S. T., Smith, R. D., Deng, W., Ho, K. Y., Lin, J., Kwok, J. Y. Y., Lam, T.-C., & Lin, C. (2020) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2020.101334 · Cited by 79 · see citing works
Exercise, sleep and cancer-related fatigue: Are they related?
Medysky, M. E., Temesi, J., Culos-Reed, S. N., & Millet, G. Y. (2017) · Neurophysiologie Clinique · doi:10.1016/j.neucli.2017.03.001 · Cited by 65 · see citing works
The effects of exercise on sleep in unipolar depression: a systematic review and network meta-analysis
Brupbacher, G., Gerger, H., Zander-Schellenberg, T., Straus, D., Porschke, H., Gerber, M., von Känel, R., & Schmidt-Trucksäss, A. (2021) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2021.101452 · Cited by 64 · see citing works
Meta‐analysis: Exercise intervention for sleep problems in cancer patients
Fang, Y., Hung, C., Chan, J., Huang, S., & Lee, Y. (2019) · European Journal of Cancer Care · doi:10.1111/ecc.13131 · Cited by 49 · see citing works
A non-inferiority randomized controlled trial comparing a home-based aerobic exercise program to a self-administered cognitive-behavioral therapy for insomnia in cancer patients
Mercier, J., Ivers, H., & Savard, J. (2018) · SLEEP · doi:10.1093/sleep/zsy149 · Cited by 46 · see citing works
“Two reviews summarizing this literature have been published [39, 40].”
Background
Sleep-Wake Disturbance: A Systematic Review of Evidence-Based Interventions for Management in Patients With Cancer
Matthews, E. E., Carter, P. A., Page, M., Dean, G. E., & Berger, A. M. (2018) · Clinical journal of oncology nursing · doi:10.1188/18.cjon.37-52 · Cited by 40 · see citing works
“A meta-analysis of nine RCTs in people with cancer concluded that moderate-intensity walking has a modest effect on sleep improvement (Chiu et al., 2015).”
Background
Nonpharmacologic Interventions for Improving Sleep Disturbances in Patients With Lung Cancer: A Systematic Review and Meta-analysis
Papadopoulos, D., Papadoudis, A., Kiagia, M., & Syrigos, K. (2018) · Journal of Pain and Symptom Management · doi:10.1016/j.jpainsymman.2017.12.491 · Cited by 40 · see citing works
Walking is more effective than yoga at reducing sleep disturbance in cancer patients: A systematic review and meta-analysis of randomized controlled trials
Tang, M.-F., Chiu, H.-Y., Xu, X., Kwok, J. Y. Y., Cheung, D. S. T., Chen, C., & Lin, C. (2019) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2019.05.003 · Cited by 36 · see citing works
Self-citation
Breast Cancer Collaborative Registry informs understanding of factors predicting sleep quality
Berger, A. M., Kupzyk, K. A., Sass, D., & Cowan, K. H. (2018) · Supportive Care in Cancer · doi:10.1007/s00520-018-4417-5 · Cited by 28 · see citing works
“Our first model supports younger age [1, 35], higher cancer-related fatigue [19–21], and lower physical activity [14, 23] as the strongest combined and independent variables in predicting sleep quality.”
Temporal relationships between sleep and physical activity among breast cancer patients with insomnia.
Bernard, P., Ivers, H., Savard, M., & Savard, J. (2016) · Health Psychology · doi:10.1037/hea0000408 · Cited by 26 · see citing works
“Two meta-analyses concluded that exercise interventions improve cancer-related sleep disturbances (Chiu et al., 2015; Tomlinson et al., 2014).”
Background
The effect of daily walking exercise on sleep quality in healthy young adults
Wang, F., & Boros, S. (2020) · Sport Sciences for Health · doi:10.1007/s11332-020-00702-x · Cited by 25 · see citing works
“Meta-analyses have exploited the benefits of moderate-intensity walking for clinical patients [25, 26], and moderate-intensity walking exercise showed efficiency in improving sleep [27].”
Background
Physical Activity, Sitting Time, and Quality of Life among Breast and Gynaecology Cancer Survivors
Zainordin, N. H., Karim, N. A., Shahril, M. R., & Talib, R. A. (2021) · Asian Pacific Journal of Cancer Prevention · doi:10.31557/apjcp.2021.22.8.2399 · Cited by 22 · see citing works
“By doing physical activity as simple as walking can help improve the quality of sleep for cancer survivors (Chiu et al., 2015).”
Background
Factors Associated With Poor Sleep in Older Women Diagnosed With Breast Cancer
Overcash, J. A., Tan, A., Patel, K. A., & Noonan, A. M. (2018) · Oncology nursing forum · doi:10.1188/18.onf.359-371 · Cited by 22 · see citing works
The influence of 12-week dance intervention on sleep quality and pain among women with breast cancer – Pilot study of a non-randomized clinical trial
Hiansdt, J. S., Boing, L., Sperandio, F. F., Fretta, T. D. B., & Guimarães, A. C. D. A. (2020) · Journal of Bodywork and Movement Therapies · doi:10.1016/j.jbmt.2020.10.004 · Cited by 20 · see citing works
The Effects of Physical Activity on Cancer Patients Undergoing Treatment with Immune Checkpoint Inhibitors: A Scoping Review
Shaver, A. L., Sharma, S., Nikita, N., Lefler, D. S., Basu-Mallick, A., Johnson, J. M., Butryn, M. L., & Lu-Yao, G. L. (2021) · Cancers · doi:10.3390/cancers13246364 · Cited by 18 · see citing works
How do I best manage insomnia and other sleep disorders in older adults with cancer?
Loh, K. P., Burhenn, P., Hurria, A., Zachariah, F. J., & Mohile, S. G. (2016) · Journal of Geriatric Oncology · doi:10.1016/j.jgo.2016.05.003 · Cited by 18 · see citing works
The relationship of daily physical activity and sleep in adults: variations by age, sex, and race
Bisson, A., & Lachman, M. E. (2023) · Journal of Behavioral Medicine · doi:10.1007/s10865-022-00387-2 · Cited by 16 · see citing works
Practical applications of grounding to support health
Koniver, L. (2022) · Biomedical Journal · doi:10.1016/j.bj.2022.12.001 · Cited by 12 · see citing works
The Impact of Physical Activity on Sleep during Pregnancy: A Secondary Analysis
Nodine, P., & Leiferman, J. A. (2016) · clinics in Mother and Child Health · doi:10.4172/2090-7214.1000245 · Cited by 9 · see citing works
“In the non-pregnant population, acute and long term physical activity has been associated with improvement in sleep quality, increased slow wave (deeper) sleep, as well as decreased SOL [3,17-19].”
Background
Exercise regimens for improved sleep quality in adult breast cancer survivors: systematic review and network meta-analysis
Hasan, F., Tu, Y., Lin, C., Yuliana, L. T., Romadlon, D. S., & Chiu, H. (2023) · BMJ Supportive & Palliative Care · doi:10.1136/spcare-2023-004363 · Cited by 8 · see citing works
Self-citation
Exploring Guolin Qigong (Mind-Body Exercise) for Improving Cancer Related Fatigue in Cancer Survivors: A Mixed Method Randomized Controlled Trial Protocol
Low, S. L. K., Ho, G. F., Liu, B., Koh, E., Fei, Y., Teo, C. S., & Zhu, X. (2024) · Integrative Cancer Therapies · doi:10.1177/15347354241252698 · Cited by 9 · see citing works
“54 A 58-60 GQ exercise training also facilitates the inhaling of oxygen which is important for the homeostasis of oxy-gen-carbon dioxide in controlling cancer and ultimately survival, as supported by a 10-year longitudinal cohort study of 122 lung and nasopharyngeal cancer patients which reported…”
Effect of different types of exercise on health-related quality of life during and after cancer treatment: a protocol for a systematic review and network meta-analysis
Ubago‐Guisado, E., Gracia‐Marco, L., Cavero‐Redondo, I., Martínez‐Vizcaíno, V., Notario‐Pacheco, B., Pozuelo‐Carrascosa, D. P., Adalia, E. G., & Álvarez-Bueno, C. (2019) · BMJ Open · doi:10.1136/bmjopen-2019-031374 · Cited by 8 · see citing works
Exercise, Health Disorders, and Injuries
Kopp, M., Niedermeier, M., & Herring, M. P. (2023) · Springer eBooks · doi:10.1007/978-3-031-03921-8_28 · Cited by 7 · see citing works
Effects of resistance training on sleep quality and disorders among individuals diagnosed with cancer: A systematic review and meta‐analysis of randomized controlled trials
Marić, D., Ficarra, S., Bartolo, L. D., Rossi, C., Asimakopoulou, Z., Vantarakis, A., Carbonell‐Baeza, A., Jiménez‐Pavón, D., Gomes, B. B., Tavares, P., et al. (2024) · Cancer Medicine · doi:10.1002/cam4.7179 · Cited by 6 · see citing works
“50,51 Taking into account the results of our systematic review and meta-analysis beneficial effects of COMB and RT on sleep outcomes are undeniable, however, some inconsistencies may indicate that methodological differences are defining the outcomes of the training interventions and should be…”
BackgroundResult
Manifestações psíquicas durante pandemia de COVID-19: revisão sistemática da literatura / Psychic manifests during pandemic COVID-19: a systematic review of the literature
de Souza, A. B., Silva, R. Y., Marrazzo, E. B., Briante, M. E. T., Franco, L. O. A., Correia, G. S., & Capobianco, J. G. P. (2021) · Brazilian Journal of Health Review · doi:10.34119/bjhrv4n2-191 · Cited by 5 · see citing works
Sleep disturbance in patients with cancer
Maqbali, M. A. H. A. (2020) · Journal of Integrative Nursing · doi:10.4103/jin.jin_48_20 · Cited by 5 · see citing works
Preoperative decreased physical activity is associated with greater postoperative pain: the mediating role of preoperative sleep disturbance
Wilson, J. M., Franqueiro, A. R., Rosado, E., Falso, V. R., Muñoz‐Vergara, D., Smith, M. T., Klerman, E. B., Shen, S., & Schreiber, K. L. (2024) · Supportive Care in Cancer · doi:10.1007/s00520-024-08625-w · Cited by 5 · see citing works
“Previous research has suggested an important link between PA and sleep, with PA predicting subsequent improvement in sleep quality [15–18].”
Effect of a Single Light-intensity Walking Session on Sleep Quality of Patients with Bladder Cancer: A Randomized Cross-Over Study
Wang, X., Liu, M., Stevinson, C. D., Dai, Y., Tang, Y., Peng, D., Yan, M.-B., Zheng, H., Liu, X.-N., Liu, Y., et al. (2023) · Seminars in Oncology Nursing · doi:10.1016/j.soncn.2023.151571 · Cited by 4 · see citing works
Effect of Exercise on Sleep in the Middle-aged and Older adult: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Eun, H.-B., & Baek, S. (2023) · Exercise Science · doi:10.15857/ksep.2023.32.1.21 · Cited by 3 · see citing works
Sleep Disturbance in Cancer Survivors
McGinty, H. L., Carroll, A. J., & Sanford, S. D. (2016) · Springer eBooks · doi:10.1007/978-3-319-41400-3_12 · Cited by 3 · see citing works
Walking transmutes the individual health system: diseases
Garg, R. K., & Sharma, B. (2022) · International Journal of Contemporary Pediatrics · doi:10.18203/2349-3291.ijcp20223434 · Cited by 2 · see citing works
Visual analysis of the research frontiers, hotspots and trends of exercise therapy intervention in tumor-related sleep-wake disorders
Han, J., Zhang, J., Zhang, L., Guo, J., Peng, X., Ying, C., Li, Z., Li, M., Chang, L., & Zhang, Y. (2024) · Frontiers in Oncology · doi:10.3389/fonc.2024.1392844 · Cited by 2 · see citing works
Cancer-related fatigue: trigger factors and function of exercise
Tórtola-Navarro, A., & Santalla, A. (2021) · Archivos de medicina del deporte: revista de la Federación Española de Medicina del Deporte y de la Confederación Iberoamericana de Medicina del Deporte · doi:10.18176/archmeddeporte.00045 · Cited by 2 · see citing works
Effects of self-monitoring physical activity with a smartphone application combined with physiotherapy coaching in patients with cancer: a randomised controlled trial (SMART-COACH trial)
Ormel, H. L., van Zutphen, E. H., van der Schoot, G. G. F., Gietema, J. A., & Walenkamp, A. (2025) · Journal of Cancer Survivorship · doi:10.1007/s11764-025-01862-w · Cited by 1 · see citing works
“The positive effect of our intervention on insomnia is in line with the results of a meta-analysis of nine randomised controlled trials that investigated moderate-intensity walking exercise in patients with cancer [53].”
Longitudinal Associations of Sedentary Behavior and Physical Activity With Sleep Duration and Quality in Individuals Living With and Beyond Colorectal Cancer
Frenken, K. G., Buffart, L., Bours, M., Breukink, S. O., Janssen-Heijnen, M., Konsten, J., Keulen, E., Siffels, A., Koster, A., Meijer, K., et al. (2025) · Cancer Control: Journal of the Moffitt Cancer Cente · doi:10.1177/10732748251397676
Sport, Krankheit und Verletzungen
Kopp, M., & Niedermeier, M. (2019) · Springer eBooks · doi:10.1007/978-3-662-56802-6_26 · Cited by 1 · see citing works
Cancer-Related Pain and Effects of Non-pharmacologic Intervention
Nakano, J. (2022) · Springer eBooks · doi:10.1007/978-981-19-6710-8_17 · Cited by 1 · see citing works
Research progress in circadian rhythms in the application of psychological rehabilitation of cancer patients.
Luo, X., Xiao, P., Li, L., Duan, Y., Sk, C. A., & Xie, J. (2022) · PubMed Central · doi:10.11817/j.issn.1672-7347.2022.220245 · Cited by 1 · see citing works
Nonpharmacological Interventions for Sleep in People With Upper Gastrointestinal Cancer: A Systematic Review and Meta-Analysis
Li, L., Wang, S., Sun, Q., Sletten, T. L., & Wiley, J. F. (2025) · Journal of Pain and Symptom Management · doi:10.1016/j.jpainsymman.2025.08.037 · Cited by 1 · see citing works
Integrative Medizin: evidenzbasierte Webseiten und Aktuelles
Kalder, M., & Dobos, G. (2018) · Der Gynäkologe · doi:10.1007/s00129-018-4325-2 · Cited by 1 · see citing works
Association between Quality of Life with Depressive Symptoms, Anxiety, Stress, and Emotional Distress in Peruvian Cancer Patients: A Cross-sectional StudyPreprint
Villarreal‐Zegarra, D., Malaquias-Obregon, S. C., García-Serna, J., Vilela-Estrada, A. L., Cabrera-Alva, M., & Copez-Lonzoy, A. J. E. (2022) · Research Square · doi:10.21203/rs.3.rs-1789695/v2 · Cited by 1 · see citing works
Integrative Onkologie bei gynäkoonkologischen Tumoren
Voiss, P., Felber, S., Lange, S., Klose, P., Kümmel, S., Paul, A., & Dobos, G. (2021) · Die Gynäkologie · doi:10.1007/978-3-662-47329-0_116-1
がん終末期における運動療法
荒金, 英. (2018) · The Japanese Journal of SURGICAL METABOLISM and NUTRITION · doi:10.11638/jssmn.52.6_317
Association between Quality of Life with Depressive Symptoms, Anxiety, Stress, and Emotional Distress in Peruvian Cancer Patients: A Cross-sectional StudyPreprint
Villarreal‐Zegarra, D., Malaquias-Obregon, S. C., García-Serna, J., Vilela-Estrada, A. L., Cabrera-Alva, M., & Copez-Lonzoy, A. J. E. (2022) · Research Square · doi:10.21203/rs.3.rs-1789695/v1
The Interaction Between Physical Activity and Sleep Quality, Stress and Life Satisfaction among Adults - Aerobic Walking Intervention
Wang, F. (2021) · Eötvös Loránd Tudományegyetem · doi:10.15476/elte.2021.015
Technology as a Means to Bridge the Gap Between Humans and Nature
Mehra, R. K. (2024) · Advances in medical education, research, and ethics (AMERE) book series · doi:10.4018/979-8-3693-1178-3.ch011
Walking Forward: Advances in Mobility for People with Neurological Disorders
Fulk, G. D., Landers, M. R., Ploughman, M., Rose, D. K., & Williams, G. P. (2025) · Neurology Report · doi:10.1097/npt.0000000000000521
Home-based supervised exercise on metastatic cancer patients receiving oral targeted therapy: the AFSOS-Unicancer QUALIOR randomized phase 2 study
Joly, F., Lefeuvre‐Plesse, C., Charton, É., Hélissey, C., Priou, F., Stefani, L., Simmet, V., Bonnet, E., Méneveau, N., Houede, N., et al. (2025) · The Oncologist · doi:10.1093/oncolo/oyaf435
The impact of mind-body and aerobic exercises on subjective and objective sleep quality in middle-aged and older adults: A systematic review and meta-analysis of randomized controlled trials
Fan, Z., Wang, Z., Li, Y., Chen, X., & Zhang, Y. (2026) · Geriatric Nursing · doi:10.1016/j.gerinurse.2026.103867
Interventions for managing clinically relevant sleep disturbances or insomnia in cancer patients and survivors: an up-to-date systematic review and meta-analysis of self-reported sleep disturbance
Chan, J., Ng, D. W. L., Fong, D. Y. T., Chan, M. C. H., Shi, Y., & Lam, W. W. T. (2026) · Frontiers in Psychology · doi:10.3389/fpsyg.2026.1811748
Nature-based physical activity in breast cancer survivors: a new frontier in supportive care
Carretti, G., Manetti, M., & Marini, M. (2026) · Oncology Reviews · doi:10.3389/or.2026.1837259
“Randomized trials also highlighted potential benefits for body composition, immune parameters, and cognitive functioning during chemotherapy (51,130–132).”

Walking is more effective than yoga at reducing sleep disturbance in cancer patients: A systematic review and meta-analysis of randomized controlled trials
Tang, M.-F., Chiu, H.-Y., Xu, X., Kwok, J. Y. Y., Cheung, D. S. T., Chen, C., & Lin, C. (2019) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2019.05.003 · Cited by 36 · see citing works
Self-citation
Exercise interventions to improve sleep in cancer patients: a systematic review and meta-analysis
Mercier, J., Savard, J., & Bernard, P. (2017) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2016.11.001 · Cited by 103 · see citing works
Walking exercise improves sleep in cancer patients and cancer survivors: A meta-analysis of randomized controlled trials
HY, C. (2014) · Taipei Medical University Repository
The Efficacy of Home-Based Walking Exercise on Sleep in Cancer Survivors: A Meta-Analysis of Randomized Controlled Trials
Chiu, H., & Chen, P. (2014) · Sigma Theta Tau International's 25th International Nursing Research Congress
Self-citation
Effects and moderators of exercise on sleep in adults with cancer: Individual patient data and aggregated meta-analyses
Bernard, P., Savard, J., Steindorf, K., Sweegers, M. G., Courneya, K. S., Newton, R. U., Aaronson, N. K., Jacobsen, P. B., May, A. M., Galvao, D. A., et al. (2019) · Journal of Psychosomatic Research · doi:10.1016/j.jpsychores.2019.109746 · Cited by 42 · see citing works

Authors: Chiu, H.-Y., Huang, H.-C., Chen, P.-Y., Hou, W.-H., & Tsai, P.-S.
Affiliations: Taipei Medical University (TW)
Cardinal Tien College of Healthcare and Management (TW)
Chang Gung University (TW)
ORCID: Huang, Hui-Chuan
Chen, Pin-Yuan
Hou, Wen-Hsuan
Tsai, Pei-Shan
Venue: Oncology Nursing Forum
Publisher: Oncology Nursing Society (ONS)
Published: 2015-02-28
Volume: 42
Issue: 2
Pages: E54-E62
ISSN: 0190-535X (ISSN-L)
1538-0688
DOI: 10.1188/15.onf.e54-e62
OpenAlex: W284536905
Cited by: 63
References: 49
Citations by year: 2026: 3 · 2025: 5 · 2024: 5 · 2023: 6 · 2022: 6 · 2021: 9 · 2020: 4 · 2019: 7 · 2018: 10 · 2017: 2 · 2016: 6
FWCI: 0.64
Type: journal article
Language: en
Open access: closed
Locations: Oncology nursing forum (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Oncology › Cancer survivorship and care
Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and related disorders
Health Sciences › Medicine › Critical Care and Intensive Care Medicine › Intensive Care Unit Cognitive Disorders
Keywords: walking exercise, sleep quality, cancer patients, sleep disorders, moderate-intensity exercise, breast cancer, exercise therapy
MeSH terms: Breast Neoplasms, Exercise Therapy, Female, Humans, Sleep Initiation and Maintenance Disorders, Male, Middle Aged, Neoplasms, Multicenter Studies as Topic, Randomized Controlled Trials as Topic, Walking, Outcome Assessment, Health Care

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Walking improves sleep in individuals with cancer: a meta-analysis of randomized, controlled trials

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