Cited by 1,902Immune cells in cancerImmune Response and InflammationPhagocytosis and Immune Regulation

The DOI matches its Crossref record; 37 of the 38 references it cites were found in a registry or an index.

The many faces of macrophage activation

Mosser, David M·2003·Journal of Leukocyte Biology

Open this paper in CoChat — free account

Abstract

Journal of Leukocyte Biology considers manuscripts of original investigations focusing on the origins, developmental biology, biochemistry and functions of granulocytes, lymphocytes, mononuclear phagocytes, and other cells involved in host defense. These include full-length papers on original research, rapid communications of new discoveries, letters, commentaries, and invited reviews.

Integrity signals

Registry

Crossref · 10.1189/jlb.0602325

Cites

37 of 37 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

NITRIC OXIDE AND MACROPHAGE FUNCTION
MacMicking, J. D., Xie, Q. W., & Nathan, C. (1997) · Annual Review of Immunology · doi:10.1146/annurev.immunol.15.1.323 · Cited by 4,245
M-1/M-2 Macrophages and the Th1/Th2 Paradigm
Mills, C. D., Kincaid, K., Alt, J. M., Heilman, M. J., & Hill, A. M. (2000) · The Journal of Immunology · doi:10.4049/jimmunol.164.12.6166 · Cited by 3,287
Interleukin 4 potently enhances murine macrophage mannose receptor activity: A marker of alternative immunologic macrophage activation
Stein, M., Keshav, S., Harris, N., & Gordon, S. (1992) · The Journal of experimental medicine · doi:10.1084/jem.176.1.287 · Cited by 1,960
Phosphatidylserine-dependent ingestion of apoptotic cells promotes TGF-beta1 secretion and the resolution of inflammation.
Huynh, M.-L. N., Fadok, V., & Henson, P. (2002) · Journal of Clinical Investigation · doi:10.1172/jci11638 · Cited by 1,333
Phosphatidylserine-dependent ingestion of apoptotic cells promotes TGF-β1 secretion and the resolution of inflammation
Huynh, M.-L. N., Fadok, V. A., & Henson, P. M. (2002) · Journal of Clinical Investigation · doi:10.1172/jci0211638 · Cited by 957
Differential Regulation of Nitric Oxide Synthase-2 and Arginase-1 by Type 1/Type 2 Cytokines In Vivo: Granulomatous Pathology Is Shaped by the Pattern of l -Arginine Metabolism
Hesse, M., Modolell, M., Flamme, A. C. L., Schito, M. L., Fuentes, J. M., Cheever, A. W., Pearce, E. J., & Wynn, T. A. (2001) · The Journal of Immunology · doi:10.4049/jimmunol.167.11.6533 · Cited by 723
Other Functions, Other Genes
Goerdt, S., & Orfanos, C. E. (1999) · Immunity · doi:10.1016/s1074-7613(00)80014-x · Cited by 678
Reciprocal regulation of the nitric oxide synthase/arginase balance in mouse bone marrow‐derived macrophages by TH 1 and TH 2 cytokines
Modolell, M., Corraliza, I. M., Link, F., Soler, G., & Eichmann, K. (1995) · European Journal of Immunology · doi:10.1002/eji.1830250436 · Cited by 554
Reprogramming of the Macrophage Transcriptome in Response to Interferon-γ and Mycobacterium tuberculosis
Ehrt, S., Schnappinger, D., Bekiranov, S., Drenkow, J., Shi, S., Gingeras, T., Gaasterland, T., Schoolnik, G. K., & Nathan, C. (2001) · The Journal of Experimental Medicine · doi:10.1084/jem.194.8.1123 · Cited by 467
Influence of alternatively and classically activated macrophages on fibrogenic activities of human fibroblasts
Song, E., Ouyang, N., Hörbelt, M., Antus, B., Wang, M., & Exton, M. S. (2000) · Cellular Immunology · doi:10.1006/cimm.2000.1687 · Cited by 447

Show all 38 references

Sorted by citations

Items 501–600 of 1,002

Resolvin D1 promotes the interleukin-4-induced alternative activation in BV-2 microglial cells
Li, L., Wu, Y., Wang, Y., Wu, J., Song, L., Xian, W., Yuan, S., Pei, L., & Shang, Y. (2014) · Journal of Neuroinflammation · doi:10.1186/1742-2094-11-72 · Cited by 81
Bone marrow-derived macrophages from aged rats are more responsive to inflammatory stimuli
Barrett, J. P., Costello, D. A., O’Sullivan, J., Cowley, T. R., & Lynch, M. A. (2015) · Journal of Neuroinflammation · doi:10.1186/s12974-015-0287-7 · Cited by 76
Biomolecular strategies to modulate the macrophage response to implanted materials
Kim, Y. K., Chen, E. Y., & Liu, W. F. (2015) · Journal of Materials Chemistry B · doi:10.1039/c5tb01605c · Cited by 82
Expression of MRP8 and MRP14 by macrophages is a marker for severe forms of glomerulonephritis
Frosch, M., Vogl, T., Waldherr, R., Sorg, C., Sunderkötter, C. H., & Roth, J. (2003) · Journal of Leukocyte Biology · doi:10.1189/jlb.0203076 · Cited by 76
Natural killer cell-mediated response to human cytomegalovirus-infected macrophages is modulated by their functional polarization
Romo, N., Magri, G., Muntasell, A., Heredia, G., Baía, D., Angulo, A., Gumá, M., & López‐Botet, M. (2011) · Journal of Leukocyte Biology · doi:10.1189/jlb.0311171 · Cited by 76
Arginase 2 deletion leads to enhanced M1 macrophage activation and upregulated polyamine metabolism in response to Helicobacter pylori infection
Hardbower, D. M., Asim, M., Stewart, T. M., Casero, R. A., Verriere, T. G., Lewis, N. D., Chaturvedi, R., Piazuelo, M. B., & Wilson, K. T. (2016) · Amino Acids · doi:10.1007/s00726-016-2231-2 · Cited by 78
Dasatinib Reduces Lung Inflammation and Fibrosis in Acute Experimental Silicosis
Cruz, F. F., Horta, L. F. B., Maia, L. D. A., Lopes‐Pacheco, M., da Silva, A. B., Morales, M. M., Gonçalves-de-Albuquerque, C. F., Takiya, C. M., Castro-Faria-Neto, H. C., & Rocco, P. R. M. (2016) · PLoS ONE · doi:10.1371/journal.pone.0147005 · Cited by 77
Multi-functional cerium oxide nanoparticles regulate inflammation and enhance osteogenesis
Wei, F., Neal, C. J., Sakthivel, T. S., Kean, T. J., Seal, S., & Coathup, M. J. (2021) · Materials Science and Engineering C · doi:10.1016/j.msec.2021.112041 · Cited by 77
The mammalian blastema: regeneration at our fingertips
Simkin, J., Sammarco, M. C., Dawson, L., Schanes, P. P., Yu, L., & Muneoka, K. (2015) · Regeneration · doi:10.1002/reg2.36 · Cited by 75
Human and Mouse Macrophages Collaborate with Neutrophils To Kill Larval Strongyloides stercoralis
Bonne-Année, S., Kerepesi, L. A., Hess, J. A., O’Connell, A. E., Lok, J. B., Nolan, T. J., & Abraham, D. (2013) · Infection and Immunity · doi:10.1128/iai.00625-13 · Cited by 74
Current Development of Nano-Drug Delivery to Target Macrophages
Cai, D., Gao, W., Li, Z., Zhang, Y., Xiao, L., & Xiao, Y. (2022) · Biomedicines · doi:10.3390/biomedicines10051203 · Cited by 74
Galectin-3 controls the response of microglial cells to limit cuprizone-induced demyelination
Hoyos, H. C., Rinaldi, M., Méndez‐Huergo, S. P., Marder, M., Rabinovich, G. A., Pasquini, J. M., & Pasquini, L. A. (2013) · Neurobiology of Disease · doi:10.1016/j.nbd.2013.10.023 · Cited by 79
Infection and Cancer: Revaluation of the Hygiene Hypothesis
Οικονομοπούλου, Κ., Brinc, D., Kyriacou, K. C., & Diamandis, E. P. (2013) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-12-3661 · Cited by 72
Brain interference: Revisiting the role of IFNγ in the central nervous system
Monteiro, S., Roque, S., Marques, F., Correia‐Neves, M., & Cerqueira, J. (2017) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2017.05.003 · Cited by 75
African trypanosomosis: From immune escape and immunopathology to immune intervention
Stijlemans, B., Guilliams, M., Raes, G., Beschin, A., Magez, S., & BAETSELIER, P. D. (2007) · Veterinary Parasitology · doi:10.1016/j.vetpar.2007.05.005 · Cited by 71
A folate receptor beta-specific human monoclonal antibody recognizes activated macrophage of rheumatoid patients and mediates antibody-dependent cell-mediated cytotoxicity
Feng, Y., Shen, J., Streaker, E. D., Lockwood, M. B., Zhu, Z., Low, P. S., & Dimitrov, D. S. (2011) · Arthritis Research & Therapy · doi:10.1186/ar3312 · Cited by 72
Immunological orchestration of zinc homeostasis: The battle between host mechanisms and pathogen defenses
Vignesh, K. S., & Deepe, G. S. (2016) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2016.02.020 · Cited by 74
StarPEG‐Heparin Hydrogels to Protect and Sustainably Deliver IL‐4
Schirmer, L., Atallah, P., Werner, C., & Freudenberg, U. (2016) · Advanced Healthcare Materials · doi:10.1002/adhm.201600797 · Cited by 72
The effect of cell debris within biologic scaffolds upon the macrophage response
Londono, R., Dziki, J. L., Haljasmaa, E., Turner, N. J., Leifer, C. A., & Badylak, S. F. (2017) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.36055 · Cited by 72
Inflammation-induced adverse pregnancy and neonatal outcomes can be improved by the immunomodulatory peptide exendin-4
Garcia-Flores, V., Romero, R., Miller, D., Xu, Y., Done, B., Veerapaneni, C., Leng, Y., Arenas-Hernandez, M., Khan, N., Panaitescu, B., et al. (2018) · Frontiers in Immunology · doi:10.3389/fimmu.2018.01291 · Cited by 71
Attenuation of Th1 effector cell responses and susceptibility to experimental allergic encephalomyelitis in histamine H2 receptor knockout mice is due to dysregulation of cytokine production by antigen-presenting cells.
Teuscher, C., Poynter, M., Offner, H., Zamora, A., Watanabe, T., Fillmore, P., Zachary, J., & Blankenhorn, E. (2004) · American Journal of Pathology · doi:10.1016/s0002-9440(10)63176-8 · Cited by 75
Macrophages: The Potent Immunoregulatory Innate Immune Cells
Kumar, V. (2019) · IntechOpen eBooks · doi:10.5772/intechopen.88013 · Cited by 76
Resveratrol Prevents Tumor Growth and Metastasis by Inhibiting Lymphangiogenesis and M2 Macrophage Activation and Differentiation in Tumor-associated Macrophages
Kimura, Y., & Sumiyoshi, M. (2016) · Nutrition and Cancer · doi:10.1080/01635581.2016.1158295 · Cited by 74
Bosutinib Therapy Ameliorates Lung Inflammation and Fibrosis in Experimental Silicosis
Carneiro, P. J., Clevelario, A. L., Padilha, G. A., Silva, J. D., Kitoko, J. Z., Olsen, P. C., Capelozzi, V. L., Rocco, P. R. M., & Cruz, F. F. (2017) · Frontiers in Physiology · doi:10.3389/fphys.2017.00159 · Cited by 70
Mesenchymal stem cell-based bioengineered constructs: foreign body response, cross-talk with macrophages and impact of biomaterial design strategies for pelvic floor disorders
Mukherjee, S., Darzi, S., Paul, K., Werkmeister, J. A., & Gargett, C. E. (2019) · Interface Focus · doi:10.1098/rsfs.2018.0089 · Cited by 74
Antigen presenting cells and HLA-G – a review
McIntire, R. H., & Hunt, J. S. (2005) · Placenta · doi:10.1016/j.placenta.2005.01.006 · Cited by 70
Foreign Body-Type Multinucleated Giant Cell Formation Is Potently Induced by α-Tocopherol and Prevented by the Diacylglycerol Kinase Inhibitor R59022
McNally, A. K., & Anderson, J. M. (2003) · The American Journal of Pathology · doi:10.1016/s0002-9440(10)63474-8 · Cited by 69
Innate and adaptive immunity in atherosclerosis
Miteva, K., Madonna, R., Caterina, R. D., & Linthout, S. V. (2018) · Vascular Pharmacology · doi:10.1016/j.vph.2018.04.006 · Cited by 70
Macrophages: From Simple Phagocyte to an Integrative Regulatory Cell for Inflammation and Tissue Regeneration—A Review of the Literature
Mamilos, A., Winter, L., Schmitt, V. H., Barsch, F., Grevenstein, D., Wagner, W. L., Babel, M., Keller, K., Schmitt, C., Gürtler, F., et al. (2023) · Cells · doi:10.3390/cells12020276 · Cited by 75
PI3K/akt, JAK/STAT and MEK/ERK pathway inhibition protects retinal ganglion cells via different mechanisms after optic nerve injury
Luo, J., Cen, L., Zhang, X., Chiang, S. W. Y., Huang, Y., Lin, D., Fan, Y., van Rooijen, N., Lam, D. S. C., Pang, C. P., et al. (2007) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2007.05718.x · Cited by 69
The activating effect of IFN-γ on monocytes/macrophages is regulated by the LIF–trophoblast–IL-10 axis via Stat1 inhibition and Stat3 activation
Dallagi, A., Girouard, J., Hamelin-Morrissette, J., Dadzie, R., Laurent, L., Vaillancourt, C., Lafond, J., Carrier, C., & Reyes‐Moreno, C. (2014) · Cellular and Molecular Immunology · doi:10.1038/cmi.2014.50 · Cited by 69
Deferoxamine enhances alternative activation of microglia and inhibits amyloid beta deposits in APP/PS1 mice
Zhang, Y., & He, M. (2017) · Brain Research · doi:10.1016/j.brainres.2017.09.019 · Cited by 71
Type II‐activated macrophages suppress the development of experimental autoimmune encephalomyelitis
Tierney, J., Kharkrang, M., & Flamme, A. C. L. (2008) · Immunology and Cell Biology · doi:10.1038/icb.2008.99 · Cited by 65
Constitutive Expression of Pentraxin 3 (PTX3) Protein by Human Amniotic Membrane Cells Leads to Formation of the Heavy Chain (HC)-Hyaluronan (HA)-PTX3 Complex
Zhang, S., Zhu, Y., Chen, S., He, H., & Tseng, S. C. G. (2014) · Journal of Biological Chemistry · doi:10.1074/jbc.m113.525287 · Cited by 69
Subinhibitory Antibiotic Therapy Alters Recurrent Urinary Tract Infection Pathogenesis through Modulation of Bacterial Virulence and Host Immunity
Goneau, L. W., Hannan, T. J., MacPhee, R. A., Schwartz, D. J., Macklaim, J. M., Gloor, G. B., RAZVI, H. A., Reid, G., Hultgren, S. J., & Burton, J. P. (2015) · mBio · doi:10.1128/mbio.00356-15 · Cited by 68
Role of Cordycepin and Adenosine on the Phenotypic Switch of Macrophages via Induced Anti-inflammatory Cytokines
Shin, S., Moon, S., Park, Y., Kwon, J., Lee, S., Lee, C., Cho, K., Ha, N., & Kim, K. (2009) · Immune Network · doi:10.4110/in.2009.9.6.255 · Cited by 68
Non-Coding RNAs: New Players in Skin Wound Healing
Herter, E. K., & Xu, N. (2017) · Advances in Wound Care · doi:10.1089/wound.2016.0711 · Cited by 69
Engineering polymer nanoparticles using cell membrane coating technology and their application in cancer treatments: Opportunities and challenges
Guo, K., Xiao, N., Liu, Y., Wang, Z., Tóth, J. S., Gyenis, J., Thakur, V. K., Oyane, A., & Shubhra, Q. T. H. (2021) · Nano Materials Science · doi:10.1016/j.nanoms.2021.12.001 · Cited by 67
Janus-faced liposomes enhance antimicrobial innate immune response in Mycobacterium tuberculosis infection
Greco, E., Quintiliani, G., Santucci, M. B., Serafino, A., Ciccaglione, A. R., Marcantonio, C., Papi, M., Maulucci, G., Delogu, G., Martino, A., et al. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1200484109 · Cited by 67
Gene expression analysis of ELF-MF exposed human monocytes indicating the involvement of the alternative activation pathway
Lupke, M., Frahm, J., Lantow, M., Maercker, C., Remondini, D., Bersani, F., & Simkó, M. (2006) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2006.03.003 · Cited by 67
Label-free identification of macrophage phenotype by fluorescence lifetime imaging microscopy
Garcia, A. A., Smith, T. D., Datta, R., Luu, T. U., Gratton, E., Potma, E. O., & Liu, W. F. (2016) · Journal of Biomedical Optics · doi:10.1117/1.jbo.21.4.046005 · Cited by 67
Impact of bone marrow mesenchymal stem cell immunomodulation on the osteogenic effects of laponite
Li, T., Liu, Z. L., Xiao, M., Yang, Z. Z., Peng, M., Li, C. D., Zhou, X. J., & Wang, J. (2018) · Stem Cell Research & Therapy · doi:10.1186/s13287-018-0818-0 · Cited by 67
How Mitochondrial Metabolism Contributes to Macrophage Phenotype and Functions
Benmoussa, K., Garaude, J., & Acín‐Pérez, R. (2018) · Journal of Molecular Biology · doi:10.1016/j.jmb.2018.07.003 · Cited by 69
IL‐4 depletion enhances host resistance and passive IgA protection against tuberculosis infection in BALB/c mice
Buccheri, S., Reljić, R., Caccamo, N., Iványi, J., Singh, M., Salerno, A., & Dieli, F. (2007) · European Journal of Immunology · doi:10.1002/eji.200636764 · Cited by 66
Pro-inflammatory cytokine-stimulated first trimester decidual cells enhance macrophage-induced apoptosis of extravillous trophoblasts
Wu, Z., Yang, H., Li, M., Yeh, C., Schatz, F., Lockwood, C. J., Di, W., & Huang, S.-T. J. (2011) · Placenta · doi:10.1016/j.placenta.2011.12.007 · Cited by 66
The Immunomodulatory Effects of Mesenchymal Stem Cells in Prevention or Treatment of Excessive Scars
Seo, B. F., & Jung, S. (2015) · Stem Cells International · doi:10.1155/2016/6937976 · Cited by 71
Establishing Porcine Monocyte-Derived Macrophage and Dendritic Cell Systems for Studying the Interaction with PRRSV-1
Singleton, H., Graham, S. P., Bodman-Smith, K. B., Frossard, J., & Steinbach, F. (2016) · Frontiers in Microbiology · doi:10.3389/fmicb.2016.00832 · Cited by 66
Monocyte-Derived Human Macrophages Mediate Anergy in Allogeneic T Cells and Induce Regulatory T Cells
Hoves, S., Krause, S. W., Schütz, C., Halbritter, D., Schölmerich, J., Herfarth, H. H., & Fleck, M. (2006) · The Journal of Immunology · doi:10.4049/jimmunol.177.4.2691 · Cited by 66
ANG II receptor blockade enhances anti-inflammatory macrophages in anti-glomerular basement membrane glomerulonephritis
Aki, K., Shimizu, A., Masuda, Y., Kuwahara, N., Arai, T., Ishikawa, A., Fujita, E., Mii, A., Natori, Y., Fukunaga, Y., et al. (2010) · American Journal of Physiology-Renal Physiology · doi:10.1152/ajprenal.00374.2009 · Cited by 65
Activation of murine macrophages by G1-4A, a polysaccharide from Tinospora cordifolia, in TLR4/MyD88 dependent manner
Gupta, P. K., Rajan, M. G. R., & Kulkarni, S. (2017) · International Immunopharmacology · doi:10.1016/j.intimp.2017.06.025 · Cited by 65
Generation of Inhibitory NFκB Complexes and Phosphorylated cAMP Response Element-binding Protein Correlates with the Anti-inflammatory Activity of Complement Protein C1q in Human Monocytes
Fraser, D. A., Arora, M., Bohlson, S. S., Lozano, E., & Tenner, A. J. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m605741200 · Cited by 65
Stimulation of Immature Lung Macrophages with Intranasal Interferon Gamma in a Novel Neonatal Mouse Model of Respiratory Syncytial Virus Infection
Empey, K. M., Orend, J. G., Peebles, R. S., Egaña, L. A., Norris, K. A., Oury, T. D., & Kolls, J. K. (2012) · PLoS ONE · doi:10.1371/journal.pone.0040499 · Cited by 66
A novel method for modeling facial allodynia associated with migraine in awake and freely moving rats
Wieseler, J. L., Ellis, A., Sprunger, D. B., Brown, K., McFadden, A., Mahoney, J. H., Rezvani, N., Maier, S. F., & Watkins, L. R. (2009) · Journal of Neuroscience Methods · doi:10.1016/j.jneumeth.2009.10.006 · Cited by 65
The IL-4Rα pathway in macrophages and its potential role in silica-induced pulmonary fibrosis
Migliaccio, C. T., Buford, M. C., Jessop, F., & Holian, A. (2007) · Journal of Leukocyte Biology · doi:10.1189/jlb.0807533 · Cited by 65
The high level of RANTES in the ectopic milieu recruits macrophages and induces their tolerance in progression of endometriosis
Wang, X.-Q., Yu, J., Luo, X., Shi, Y., Wang, Y., Wang, L., & Li, D. (2010) · Journal of Molecular Endocrinology · doi:10.1677/jme-09-0177 · Cited by 65
Shaping the Murine Macrophage Phenotype: IL-4 and Cyclic AMP Synergistically Activate the Arginase I Promoter
Sheldon, K. E., Shandilya, H. K., Kepka‐Lenhart, D., Poljakovic, M., Ghosh, A., & Morris, S. M. (2013) · The Journal of Immunology · doi:10.4049/jimmunol.1202102 · Cited by 65
G1-4A, a Polysaccharide from Tinospora cordifolia Inhibits the Survival of Mycobacterium tuberculosis by Modulating Host Immune Responses in TLR4 Dependent Manner
Gupta, P. K., Chakraborty, P., Kumar, S., Singh, P. K., Rajan, M. G. R., Sainis, K. B., & Kulkarni, S. (2016) · PLoS ONE · doi:10.1371/journal.pone.0154725 · Cited by 69
Activation of human mononuclear cells by porcine biologic meshes in vitro
Orenstein, S. B., Qiao, Y., Klueh, U., Kreutzer, D. L., & Novitsky, Y. W. (2010) · Hernia · doi:10.1007/s10029-010-0634-7 · Cited by 76
The Effects of Propolis and its Isolated Compounds on Cytokine Production by Murine Macrophages
Bachiega, T. F., Orsatti, C. L., Pagliarone, A. C., & Sforcin, J. M. (2012) · Phytotherapy Research · doi:10.1002/ptr.3731 · Cited by 65
CD40 Signaling in Macrophages Induces Activity against an Intracellular Pathogen Independently of Gamma Interferon and Reactive Nitrogen Intermediates
Andrade, R. M., Portillo, J. C., Wessendarp, M., & Subauste, C. S. (2005) · Infection and Immunity · doi:10.1128/iai.73.5.3115-3123.2005 · Cited by 64
Role of Hcp, a type 6 secretion system effector, of Aeromonas hydrophila in modulating activation of host immune cells
Suárez, G., Sierra, J. C., Kirtley, M. L., & Chopra, A. K. (2010) · Microbiology · doi:10.1099/mic.0.041277-0 · Cited by 64
Aspirin-triggered lipoxin enhances macrophage phagocytosis of bacteria while inhibiting inflammatory cytokine production
Prescott, D., & McKay, D. M. (2011) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00042.2011 · Cited by 64
Recovery of cardiac function mediated by MSC and interleukin-10 plasmid functionalised scaffold
Holladay, C. A., Duffy, A. M., Chen, X., Sefton, M. V., O’Brien, T., & Pandit, A. S. (2011) · Biomaterials · doi:10.1016/j.biomaterials.2011.10.019 · Cited by 65
Roles of alternatively activated M2 macrophages in allergic contact dermatitis
Suzuki, K., Meguro, K., Nakagomi, D., & Nakajima, H. (2017) · Allergology International · doi:10.1016/j.alit.2017.02.015 · Cited by 62
Revisiting the putative role of heme as a trigger of inflammation
Vallelian, F., Schaer, C. A., Deuel, J., Ingoglia, G., Humar, R., Buehler, P. W., & Schaer, D. J. (2018) · Pharmacology Research & Perspectives · doi:10.1002/prp2.392 · Cited by 63
New Insights into NF-κB Signaling in Innate Immunity: Focus on Immunometabolic Crosstalks
Iacobazzi, D., Convertini, P., Todisco, S., Santarsiero, A., Iacobazzi, V., & Infantino, V. (2023) · Biology · doi:10.3390/biology12060776 · Cited by 69
Protective Effect of MFG-E8 after Cutaneous Ischemia–Reperfusion Injury
Uchiyama, A., Yamada, K., Perera, B., Ogino, S., Yokoyama, Y., Takeuchi, Y., Ishikawa, O., & Motegi, S. (2014) · Journal of Investigative Dermatology · doi:10.1038/jid.2014.515 · Cited by 63
In Vivo Downregulation of Innate and Adaptive Immune Responses in Corneal Allograft Rejection by HC-HA/PTX3 Complex Purified From Amniotic Membrane
He, H., Tan, Y., Duffort, S., Perez, V. L., & Tseng, S. C. G. (2014) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.13-13094 · Cited by 65
Pulmonary surfactant protein A and surfactant lipids upregulate IRAK-M, a negative regulator of TLR-mediated inflammation in human macrophages
Nguyen, H. A., Rajaram, M. V. S., Meyer, D. A., & Schlesinger, L. S. (2012) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.00067.2012 · Cited by 63
Interleukin-4 induction of the CC chemokine TARC (CCL17) in murine macrophages is mediated by multiple STAT6 sites in the TARC gene promoter
Liddiard, K., Welch, J. S., Lozach, J., Heinz, S., Glass, C. K., & Greaves, D. R. (2006) · BMC Molecular Biology · doi:10.1186/1471-2199-7-45 · Cited by 65
Hookworm-Induced Persistent Changes to the Immunological Environment of the Lung
Reece, J. J., Siracusa, M. C., Southard, T. L., Brayton, C. F., Urban, J. F., & Scott, A. L. (2008) · Infection and Immunity · doi:10.1128/iai.00192-08 · Cited by 60
Atmospheric pressure plasma assisted immobilization of hyaluronic acid on tissue engineering PLA-based scaffolds and its effect on primary human macrophages
Kudryavtseva, V., Stankevich, K. S., Gudima, A., Kibler, E., Zhukov, Y. M., Больбасов, Е. Н., Malashicheva, A., Zhuravlev, M. V., Riabov, V., Liu, T., et al. (2017) · Materials & Design · doi:10.1016/j.matdes.2017.04.079 · Cited by 63
Phagocytes: mechanisms of inflammation and tissue destruction
Liu, H., & Pope, R. M. (2004) · Rheumatic Disease Clinics of North America · doi:10.1016/s0889-857x(03)00107-8 · Cited by 63
Dynamic regulation of the P2X4 receptor in alveolar macrophages by phagocytosis and classical activation
Stokes, L., & Surprenant, A. (2009) · European Journal of Immunology · doi:10.1002/eji.200838818 · Cited by 62
Transplantation of Encapsulated Pancreatic Islets as a Treatment for Patients with Type 1 Diabetes Mellitus
Qi, M. (2014) · Advances in Medicine · doi:10.1155/2014/429710 · Cited by 66
The involvement of hypoxia-inducible factor 1 alpha in Toll-like receptor 7/8-mediated inflammatory response
Nicholas, S. A., & Sumbayev, V. V. (2009) · Cell Research · doi:10.1038/cr.2009.44 · Cited by 62
Molecular mechanisms regulating macrophage response to hypoxia
Rahat, M. A. (2011) · Frontiers in Immunology · doi:10.3389/fimmu.2011.00045 · Cited by 63
The Expression of Tumor-Associated Macrophages in Papillary Thyroid Carcinoma
Kim, S., Cho, S. W., Min, H. S., Kim, K. M., Yeom, G. J., Kim, E. Y., Lee, K. E., Yun, Y. G., Park, D. J., & Park, Y. J. (2013) · Endocrinology and Metabolism · doi:10.3803/enm.2013.28.3.192 · Cited by 63
Moderate oxygen augments lipopolysaccharide-induced lung injury in mice
Aggarwal, N. R., D’Alessio, F. R., Tsushima, K., Files, D. C., Damarla, M., Sidhaye, V. K., Fraig, M., Polotsky, V. Y., & King, L. S. (2009) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.00308.2009 · Cited by 63
Human Amnion Epithelial Cells do Not Abrogate Pulmonary Fibrosis in Mice with Impaired Macrophage Function
Murphy, S. V., Shiyun, S. C., Tan, J. L., Chan, S. T., Jenkin, G., Wallace, E. M., & Lim, R. (2012) · Cell Transplantation · doi:10.3727/096368911x601028 · Cited by 61
Loss of solute carrier family 7 member 2 exacerbates inflammation-associated colon tumorigenesis
Coburn, L. A., Singh, K., Asim, M., Barry, D. P., Allaman, M. M., Al-Greene, N. T., Hardbower, D. M., Polosukhina, D., Williams, C. S., Delgado, A. G., et al. (2018) · Oncogene · doi:10.1038/s41388-018-0492-9 · Cited by 61
Triggering receptor expressed on myeloid cells (TREM-1) is regulated post-transcriptionally and its ligand is present in the sera of some septic patients
Wong‐Baeza, I., González-Roldán, N., Ferat-Osorio, E. A., Esquivel-Callejas, N., Aduna-Vicente, R., Arriaga‐Pizano, L., la Vega, H. A., Villasís-Keever, M. Á., Torres-González, R., Estrada‐García, I., et al. (2006) · Clinical & Experimental Immunology · doi:10.1111/j.1365-2249.2006.03158.x · Cited by 62
Contribution of macrophages to fetomaternal immunological tolerance
Parasar, P., Guru, N., & Nayak, N. R. (2021) · Human Immunology · doi:10.1016/j.humimm.2021.02.013 · Cited by 61
Tuning macrophages for atherosclerosis treatment
Fang, F., Xiao, C., Li, C., Liu, X., & Li, S. (2022) · Regenerative Biomaterials · doi:10.1093/rb/rbac103 · Cited by 65
INFECTION-INDUCED MODULATION OF M1 AND M2 PHENOTYPES IN CIRCULATING MONOCYTES: ROLE IN IMMUNE MONITORING AND EARLY PROGNOSIS OF SEPSIS
Mehta, A., Brewington, R., Chatterji, M., Zoubine, M. N., Kinasewitz, G. T., Peer, G. T., Chang, A. C. K., Taylor, F. B., & Shnyra, A. (2004) · Shock · doi:10.1097/01.shk.0000142184.49976.0c · Cited by 61
Pirfenidone inhibits macrophage infiltration in 5/6 nephrectomized rats
Chen, J., Ni, H.-F., Pan, M., Liu, H., Xu, M., Zhang, M., & Liu, B. (2012) · American Journal of Physiology-Renal Physiology · doi:10.1152/ajprenal.00507.2012 · Cited by 61
Carcinogenesis induced by foreign bodies
Moizhess, T. G. (2008) · Biochemistry (Moscow) · doi:10.1134/s0006297908070043 · Cited by 61
Effects of nanocrystalline hydroxyapatites on macrophage polarization
Linares, J., Fernández, A. B., Feito, M. J., Matesanz, M. C., Sánchez‐Salcedo, S., Arcos, D., Vallet‐Regí, M., Rojo, J. M., & Portolés, M. T. (2016) · Journal of Materials Chemistry B · doi:10.1039/c6tb00014b · Cited by 62
3D Printed Pericardium Hydrogels To Promote Wound Healing in Vascular Applications
Bracaglia, L. G., Messina, M. J., Winston, S., Kuo, C., Lerman, M. J., & Fisher, J. P. (2017) · Biomacromolecules · doi:10.1021/acs.biomac.7b01165 · Cited by 62
Cycling hypoxia promotes a pro-inflammatory phenotype in macrophages via JNK/p65 signaling pathway
Delprat, V., Tellier, C., Demazy, C., Raes, M. J., Féron, O., & Michiels, C. (2020) · Scientific Reports · doi:10.1038/s41598-020-57677-5 · Cited by 69
M2b Macrophages Regulate Cardiac Fibroblast Activation and Alleviate Cardiac Fibrosis After Reperfusion Injury
Yuan, Y., Huang, S., Wang, L., Wu, Z., Liang, M., Li, H., Lv, L., Li, W., & Wu, Z. (2020) · Circulation Journal · doi:10.1253/circj.cj-19-0959 · Cited by 60
Comparison of Macrophage Responses to African Swine Fever Viruses Reveals that the NH/P68 Strain is Associated with Enhanced Sensitivity to Type I IFN and Cytokine Responses from Classically Activated Macrophages
Franzoni, G., Razzuoli, E., Giudici, S. D., Carta, T., Galleri, G., Zinellu, S., Ledda, M., Angioi, P., Modesto, P., Graham, S. P., et al. (2020) · Pathogens · doi:10.3390/pathogens9030209 · Cited by 60
Macrophage Phenotype in the Ocular Surface of Experimental Murine Dry Eye Disease
You, I. C., Coursey, T. G., Bian, F., Barbosa, F. L., de Paiva, C. S., & Pflugfelder, S. C. (2015) · Archivum Immunologiae et Therapiae Experimentalis · doi:10.1007/s00005-015-0335-0 · Cited by 60
A Novel Strategy for Inducing the Antitumor Effects of Triterpenoid Compounds: Blocking the Protumoral Functions of Tumor-Associated Macrophages via STAT3 Inhibition
Fujiwara, Y., Takeya, M., & Komohara, Y. (2014) · BioMed Research International · doi:10.1155/2014/348539 · Cited by 60
RETRACTED: The Uptake of Apoptotic Cells Drives Coxiella burnetii Replication and Macrophage Polarization: A Model for Q Fever Endocarditis
Benoit, M. E., Ghigo, É., Capo, C., Raoult, D., & Mège, J. (2008) · PLoS Pathogens · doi:10.1371/journal.ppat.1000066 · Cited by 60
Retracted
The impact of neuroimmune changes on development of amyloid pathology; relevance to A lzheimer's disease
Lynch, M. A. (2013) · Immunology · doi:10.1111/imm.12156 · Cited by 64
Subpopulations of Mouse Testicular Macrophages and their Immunoregulatory Function
Bryniarski, K., Szczepanik, M., Maresz, K., Ptak, M., & Ptak, W. (2004) · American Journal of Reproductive Immunology · doi:10.1111/j.1600-0897.2004.00178.x · Cited by 60
Diet-induced (epigenetic) changes in bone marrow augment atherosclerosis
van Kampen, E., Jaminon, A. M. G., van Berkel, T. J. C., & Eck, M. V. (2014) · Journal of Leukocyte Biology · doi:10.1189/jlb.1a0114-017r · Cited by 60
Macrophages: Key regulators of steady-state and demand-adapted hematopoiesis
McCabe, A. F., & MacNamara, K. C. (2016) · Experimental Hematology · doi:10.1016/j.exphem.2016.01.003 · Cited by 62
Macrophages Orchestrate Hematopoietic Programs and Regulate HSC Function During Inflammatory Stress
Seyfried, A. N., Maloney, J., & MacNamara, K. C. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.01499 · Cited by 61

Authors: Mosser, D. M.
Affiliations: University of Maryland, College Park (US)
Corresponding author: Mosser, David M
ORCID: Mosser, David M
Venue: Journal of Leukocyte Biology
Publisher: Oxford University Press (OUP)
Published: 2003-02-01
Volume: 73
Issue: 2
Pages: 209-212
ISSN: 0741-5400 (ISSN-L)
1938-3673
DOI: 10.1189/jlb.0602325
OpenAlex: W2016293419
Cited by: 1,902
References: 38
Citations by year: 2026: 16 · 2025: 30 · 2024: 57 · 2023: 42 · 2022: 67 · 2021: 76 · 2020: 68 · 2019: 81 · 2018: 65 · 2017: 92 · 2016: 115 · 2015: 111 · 2014: 139 · 2013: 129 · 2012: 133
FWCI: 5.27
Type: journal article
Language: en
Open access: closed
Licence: academic.oup.com/pages/standard-publication-reuse-rights (vor)
Locations: Journal of Leukocyte Biology (publishedVersion)
PubMed (publishedVersion)
Topics: Life Sciences › Immunology and Microbiology › Immunology › Immune cells in cancer
Life Sciences › Immunology and Microbiology › Immunology › Immune Response and Inflammation
Life Sciences › Immunology and Microbiology › Immunology › Phagocytosis and Immune Regulation
Keywords: macrophage activation, macrophages, mononuclear phagocytes, host defense, granulocytes, lymphocytes, cell development
MeSH terms: Animals, Humans, Interferon-gamma, Macrophage Activation, Macrophages, Interleukin-4, Interleukin-10

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

The many faces of macrophage activation

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks