Cited by 280Cardiac Health and Mental HealthMental Health Treatment and AccessAnxiety, Depression, Psychometrics, Treatment, Cognitive Processes

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Levels of anxiety and depression as predictors of mortality: the HUNT study

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Mykletun, Arnstein, Bjerkeset, Ottar, øverland, Simon, Prince, Martin, Dewey, Michael, Stewart, Robert·2009·British Journal of Psychiatry

DOI 10.1192/bjp.bp.108.054866

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Abstract

BACKGROUND: Depression is reported to be associated with increased mortality, although underlying mechanisms are uncertain. Associations between anxiety and mortality are also uncertain. AIMS: To investigate associations between individual and combined anxiety/depression symptom loads (using the Hospital Anxiety and Depression Scale (HADS)) and mortality over a 3-6 year period. METHOD: We utilised a unique link between a large population survey (HUNT-2, n = 61 349) and a comprehensive mortality database. RESULTS: Case-level depression was associated with increased mortality (hazard ratio (HR) = 1.52, 95% CI 1.35-1.72) comparable with that of smoking (HR = 1.59, 95% CI 1.44-1.75), and which was only partly explained by somatic symptoms/conditions. Anxiety comorbid with depression lowered mortality compared with depression alone (anxiety depression interaction P = 0.017). The association between anxiety symptom load and mortality was U-shaped. CONCLUSIONS: Depression as a risk factor for mortality was comparable in strength to smoking. Comorbid anxiety reduced mortality compared with depression alone. The relationship between anxiety symptoms and mortality was more complex with a U-shape and highest mortality in those with the lowest anxiety symptom loads.

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Diagnostic and Statistical Manual of Mental Disorders
Williams, J. B. W., & First, M. B. (2013) · Oxford University Press eBooks · doi:10.1093/acrefore/9780199975839.013.104 · Cited by 109,845
The Hospital Anxiety and Depression Scale
Zigmond, A. S., & Snaith, R. P. (1983) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.1983.tb09716.x · Cited by 47,139
The validity of the Hospital Anxiety and Depression Scale
Bjelland, I., Dahl, A. A., Haug, T. T., & Neckelmann, D. (2002) · Journal of Psychosomatic Research · doi:10.1016/s0022-3999(01)00296-3 · Cited by 9,779
Depression as a risk factor for mortality in patients with coronary heart disease: a meta-analysis
Barth, J., Schumacher, M., & Herrmann-Lingen, C. (2004) · Psychosomatic Medicine · doi:10.1097/01.psy.0000146332.53619.b2 · Cited by 1,358
Prognostic Association of Depression Following Myocardial Infarction With Mortality and Cardiovascular Events: A Meta-analysis
van Melle, J. P., de Jonge, P., Spijkerman, T. A., Tijssen, J. G. P., Ormel, J., van Veldhuisen, D. J., van den Brink, R. H. S., & van den Berg, M. P. (2004) · Psychosomatic Medicine · doi:10.1097/01.psy.0000146294.82810.9c · Cited by 1,034
Hospital Anxiety and Depression (HAD) scale: Factor structure, item analyses and internal consistency in a large population
Mykletun, A., Stordal, E., & Dahl, A. A. (2001) · British Journal of Psychiatry · doi:10.1192/bjp.179.6.540 · Cited by 908
Depression as a Risk Factor for Coronary Artery Disease: Evidence, Mechanisms, and Treatment
Lett, H. S., Blumenthal, J. A., Babyak, M. A., Sherwood, A., Strauman, T. J., Robins, C., & Newman, M. F. (2004) · Psychosomatic Medicine · doi:10.1097/01.psy.0000126207.43307.c0 · Cited by 847
Excess mortality in depression: a meta-analysis of community studies
Cuijpers, P. J., & Smit, F. (2002) · Journal of Affective Disorders · doi:10.1016/s0165-0327(01)00413-x · Cited by 798
Depression as a risk factor for cardiac mortality and morbidity
Carney, R. M., Freedland, K. E., Miller, G. E., & Jaffe, A. S. (2002) · Journal of Psychosomatic Research · doi:10.1016/s0022-3999(02)00311-2 · Cited by 746
A systematic review of the mortality of depression
Wulsin, L. R., Vaillant, G. E., & Wells, V. E. (1999) · Psychosomatic Medicine · doi:10.1097/00006842-199901000-00003 · Cited by 703 · cited 2×
“31,33 Despite some controversy over the evidence for this association, potential mechanisms have been suggested.”

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Research works printed but not linked: 5

1980, Diagnostic and Statistical Manual of Mental Disorders (3rd edn) (DSM–III)
1967, International Statistical Classification of Diseases and Related Health Problems (ICD–8)
10.1016/S0895-4356(03)00254-3 · DOI
10.1176/ajp.2006.163.8.1412 · DOI · Paper page
1978, International Statistical Classification of Diseases and Related Health Problems (ICD–9)

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Authors: Mykletun, A., Bjerkeset, O., øverland, S., Prince, M., Dewey, M., & Stewart, R.
Affiliations: Norwegian Institute of Public Health (NO)
Norwegian University of Science and Technology (NO)
University of Bergen (NO)
King's College London (GB)
Corresponding author: Mykletun, Arnstein
ORCID: Mykletun, Arnstein
Bjerkeset, Ottar
øverland, Simon
Prince, Martin
Dewey, Michael
Stewart, Robert
Venue: British Journal of Psychiatry
Publisher: Royal College of Psychiatrists
Published: 2009-08
Volume: 195
Issue: 2
Pages: 118-125
ISSN: 0007-1250 (ISSN-L)
1472-1465
DOI: 10.1192/bjp.bp.108.054866
OpenAlex: W2147161932
Cited by: 279
References: 43
Citations by year: 2026: 1 · 2025: 2 · 2024: 3 · 2023: 13 · 2022: 14 · 2021: 22 · 2020: 19 · 2019: 14 · 2018: 15 · 2017: 12 · 2016: 20 · 2015: 11 · 2014: 22 · 2013: 35 · 2012: 17
FWCI: 15.52
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: www.cambridge.org/core/terms (unspecified, 3076 d)
Locations: The British Journal of Psychiatry (publishedVersion)
PubMed (publishedVersion)
Research Portal (King's College London) (submittedVersion)
Funders: Norges Teknisk-Naturvitenskapelige Universitet
National Institute for Health and Care Research
King's College London
Norges Forskningsråd
Norwegian Institute of Public Health
Topics: Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Health and Mental Health
Health Sciences › Medicine › Psychiatry and Mental health › Mental Health Treatment and Access
Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
Keywords: depression, anxiety, mortality, comorbid depression and anxiety, Hospital Anxiety and Depression Scale, smoking, somatic symptoms, U-shaped relationship, HUNT study, risk factors
MeSH terms: Adult, Aged, Anxiety Disorders, Cause of Death, Depressive Disorder, Epidemiologic Methods, Female, Humans, Male, Middle Aged, Norway, Comorbidity, Confounding Factors, Epidemiologic, Young Adult

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Levels of anxiety and depression as predictors of mortality: the HUNT study

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