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Cited by 183

The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.

Plasma PCSK9 preferentially reduces liver LDL receptors in mice

Grefhorst, Aldo, McNutt, Markey C., Lagace, Thomas A., Horton, Jay D.·2008·Journal of Lipid Research
DOI 10.1194/jlr.m800027-jlr200
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Research works printed but not linked: 26

  1. Rashid, 2005, Decreased plasma cholesterol and hypersensitivity to statins in mice lacking Pcsk9, Proc. Natl. Acad. Sci. USA., 102, 5374, 10.1073/pnas.0501652102 · DOI · Paper page
  2. Park, 2004, Post-transcriptional regulation of low density lipoprotein receptor protein by proprotein convertase subtilisin/kexin type 9a in mouse liver, J. Biol. Chem., 279, 50630, 10.1074/jbc.M410077200 · DOI · Paper page
  3. Maxwell, 2004, Adenoviral-mediated expression of Pcsk9 in mice results in a low-density lipoprotein receptor knockout phenotype, Proc. Natl. Acad. Sci. USA., 101, 7100, 10.1073/pnas.0402133101 · DOI · Paper page
  4. Benjannet, 2004, NARC-1/PCSK9 and its natural mutants: zymogen cleavage and effects on the low density lipoprotein (LDL) receptor and LDL cholesterol, J. Biol. Chem., 279, 48865, 10.1074/jbc.M409699200 · DOI · Paper page
  5. Abifadel, 2003, Mutations in PCSK9 cause autosomal dominant hypercholesterolemia, Nat. Genet., 34, 154, 10.1038/ng1161 · DOI · Paper page
  6. Scartezini, 2007, The PCSK9 gene R46L variant is associated with lower plasma lipid levels and cardiovascular risk in healthy UK men, Clin. Sci., 113, 435, 10.1042/CS20070150 · DOI
  7. Lagace, 2006, Secreted PCSK9 decreases LDL receptors in hepatocytes and in livers of parabiotic mice, J. Clin. Invest., 116, 2995, 10.1172/JCI29383 · DOI · Paper page
  8. Mayne, 2007, Plasma PCSK9 levels correlate with cholesterol in men but not in women, Biochem. Biophys. Res. Commun., 361, 451, 10.1016/j.bbrc.2007.07.029 · DOI · Paper page
  9. Alborn, 2007, Serum proprotein convertase subtilisin kexin type 9 is correlated directly with serum LDL cholesterol, Clin. Chem., 53, 1814, 10.1373/clinchem.2007.091280 · DOI
  10. Zhang, 2007, Binding of proprotein convertase subtilisin/kexin type 9 to epidermal growth factor-like repeat A of low density lipoprotein receptor decreases receptor recycling and increases degradation, J. Biol. Chem., 282, 18602, 10.1074/jbc.M702027200 · DOI · Paper page
  11. Kwon, 2008, Molecular basis for LDL receptor recognition by PCSK9, Proc. Natl. Acad. Sci. USA., 105, 1820, 10.1073/pnas.0712064105 · DOI · Paper page
  12. Maxwell, 2005, Overexpression of PCSK9 accelerates the degradation of the LDLR in a post-endoplasmic reticulum compartment, Proc. Natl. Acad. Sci. USA., 102, 2069, 10.1073/pnas.0409736102 · DOI · Paper page
  13. Nassoury, 2007, The cellular trafficking of the secretory proprotein convertase PCSK9 and its dependence on the LDLR, Traffic., 8, 718, 10.1111/j.1600-0854.2007.00562.x · DOI · Paper page
  14. Reeves, 1996, Structure and function in rhodopsin: high level expression of a synthetic bovine opsin gene and its mutants in stable mammalian cell lines, Proc. Natl. Acad. Sci. USA., 93, 11487, 10.1073/pnas.93.21.11487 · DOI
  15. McNutt, 2007, Catalytic activity is not required for secreted PCSK9 to reduce low density lipoprotein receptors in HepG2 cells, J. Biol. Chem., 282, 20799, 10.1074/jbc.C700095200 · DOI · Paper page
  16. Ishibashi, 1993, Hypercholesterolemia in low density lipoprotein receptor knockout mice and its reversal by adenovirus-mediated gene delivery, J. Clin. Invest., 92, 883, 10.1172/JCI116663 · DOI · Paper page
  17. Shimano, 1996, Overproduction of cholesterol and fatty acids causes massive liver enlargement in transgenic mice expressing truncated SREBP-1a, J. Clin. Invest., 98, 1575, 10.1172/JCI118951 · DOI
  18. Horton, 1999, Disruption of LDL receptor gene in transgenic SREBP-1a mice unmasks hyperlipidemia resulting from production of lipid-rich VLDL, J. Clin. Invest., 103, 1067, 10.1172/JCI6246 · DOI
  19. Engelking, 2004, Overexpression of Insig-1 in the livers of transgenic mice inhibits SREBP processing and reduces insulin-stimulated lipogenesis, J. Clin. Invest., 113, 1168, 10.1172/JCI20978 · DOI · Paper page
  20. Kovanen, 1980, Regulation of low density lipoprotein receptors by adrenocorticotropin in the adrenal gland of mice and rats in vivo, J. Biol. Chem., 255, 5591, 10.1016/S0021-9258(19)70671-1 · DOI
  21. Fisher, 2007, Effects of pH and low density lipoprotein (LDL) on PCSK9-dependent LDL receptor regulation, J. Biol. Chem., 282, 20502, 10.1074/jbc.M701634200 · DOI · Paper page
  22. Cunningham, 2007, Structural and biophysical studies of PCSK9 and its mutants linked to familial hypercholesterolemia, Nat. Struct. Mol. Biol., 14, 413, 10.1038/nsmb1235 · DOI · Paper page
  23. Seidah, 2003, The secretory proprotein convertase neural apoptosis-regulated convertase 1 (NARC-1): liver regeneration and neuronal differentiation, Proc. Natl. Acad. Sci. USA., 100, 928, 10.1073/pnas.0335507100 · DOI · Paper page
  24. Li, 2007, Secreted PCSK9 promotes LDL receptor degradation independently of proteolytic activity, Biochem. J., 406, 203, 10.1042/BJ20070664 · DOI
  25. Horton, 2003, Combined analysis of oligonucleotide microarray data from transgenic and knockout mice identifies direct SREBP target genes, Proc. Natl. Acad. Sci. USA., 100, 12027, 10.1073/pnas.1534923100 · DOI · Paper page
  26. Jeong, 2008, Sterol-dependent regulation of proprotein convertase subtilisin/kexin type 9 expression by sterol-regulatory element binding protein-2, J. Lipid Res., 49, 399, 10.1194/jlr.M700443-JLR200 · DOI · Paper page

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Metadata

Authors
Grefhorst, A., McNutt, M. C., Lagace, T. A., & Horton, J. D.
Venue
Journal of Lipid Research
Publisher
Elsevier BV
Published
2008-06
Volume
49
Issue
6
Pages
1303-1311
ISSN
0022-2275
DOI
10.1194/jlr.m800027-jlr200
Cited by
183
References
4
Language
en
Licence

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