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Xu, Y., Zhu, G., Maroun, C. A., Wu, X., Huang, D., Seiwert, T. Y., Liu, Y., Mandal, R., & Zhang, X. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.645170 · Cited by 45 · see citing works

Randomized Phase II Study Evaluating the Addition of Pembrolizumab to Radium-223 in Metastatic Castration-resistant Prostate Cancer

Choudhury, A. D., Kwak, L., Cheung, A., Allaire, K. M., Marquez, J., Yang, D. D., Tripathi, A., Kilar, J. M., Flynn, M., Maynard, B., et al. (2024) · Cancer Immunology Research · doi:10.1158/2326-6066.cir-22-0306 · Cited by 46 · see citing works

Imaging approaches and radiomics: toward a new era of ultraprecision radioimmunotherapy?

Sun, R., Henry, T., Laville, A., Carré, A., Hamaoui, A., Bockel, S., Chaffai, I., Lévy, A., Chargari, C., Robert, C., et al. (2022) · Journal for ImmunoTherapy of Cancer · doi:10.1136/jitc-2022-004848 · Cited by 31 · see citing works

Proceedings of the National Cancer Institute Workshop on combining immunotherapy with radiotherapy: challenges and opportunities for clinical translation

Morris, Z. S., Demaria, S., Monjazeb, A. M., Formenti, S. C., Weichselbaum, R. R., Welsh, J. D., Enderling, H., Schoenfeld, J. D., Brody, J., McGee, H. M., et al. (2025) · The Lancet Oncology · doi:10.1016/s1470-2045(24)00656-9 · Cited by 46 · see citing works

Anti-PD-1/Anti-PD-L1 Drugs and Radiation Therapy: Combinations and Optimization Strategies

Boustani, J., Lecoester, B., Baude, J., Latour, C., Adotévi, O., Mirjolet, C., & Truc, G. (2021) · Cancers · doi:10.3390/cancers13194893 · Cited by 38 · see citing works

Safety and Tolerability of Low-Dose Radiation and Stereotactic Body Radiotherapy + Sintilimab for Treatment-Naïve Stage IV PD-L1+ Non–Small Cell Lung Cancer Patients

Zhou, X., Zhou, L., Yao, Z., Huang, M., Gong, Y., Zou, B., Zhu, J., Liu, Y., Peng, F., Zhang, Y., et al. (2023) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-23-0315 · Cited by 41 · see citing works

Radiation as an immune modulator: mechanisms and implications for combination with immunotherapy

Darragh, L. B., & Karam, S. D. (2026) · Nature reviews. Cancer · doi:10.1038/s41568-025-00903-x · Cited by 48 · see citing works

Combining Radiotherapy and Immunotherapy in Head and Neck Cancer

Runnels, J., Bloom, J. R., Hsieh, K., Dickstein, D. R., Shi, Y., Jones, B. M., Lehrer, E. J., & Bakst, R. L. (2023) · Biomedicines · doi:10.3390/biomedicines11082097 · Cited by 38 · see citing works

Severe Lymphopenia During Chemoradiation Therapy for Esophageal Cancer: Comprehensive Analysis of Randomized Phase 2B Trial of Proton Beam Therapy Versus Intensity Modulated Radiation Therapy

Wang, X. W., van Rossum, P. S. N., Chu, Y., Hobbs, B. P., Grassberger, C., Hong, T. S., Liao, Z. X., Yang, J., Zhang, X., Netherton, T., et al. (2023) · International Journal of Radiation Oncology*Biology*Physics · doi:10.1016/j.ijrobp.2023.08.058 · Cited by 38 · see citing works

The Next Chapter in Immunotherapy and Radiation Combination Therapy: Cancer-Specific Perspectives

Wisdom, A. J., Barker, C. A., Chang, J. Y., Demaria, S., Formenti, S. C., Grassberger, C., Gregucci, F., Hoppe, B. S., Kirsch, D. G., Marciscano, A. E. E., et al. (2024) · International Journal of Radiation Oncology*Biology*Physics · doi:10.1016/j.ijrobp.2023.12.046 · Cited by 38 · see citing works

Gold-siRNA supraclusters enhance the anti-tumor immune response of stereotactic ablative radiotherapy at primary and metastatic tumors

Jiang, Y., Cao, H., Deng, H., Guan, L., Langthasa, J., Colburg, D. R. C., Melemenidis, S., Cotton, R. M., Aleman, J., Wang, X., et al. (2024) · Nature Biotechnology · doi:10.1038/s41587-024-02448-0 · Cited by 39 · see citing works

Immunotherapeutic strategies in head and neck cancer: challenges and opportunities

Liu, X., Harbison, R. A., Varvares, M. A., Puram, S. V., & Peng, G. (2025) · Journal of Clinical Investigation · doi:10.1172/jci188128 · Cited by 38 · see citing works

Tumor-Specific Antibody, Cetuximab, Enhances the In Situ Vaccine Effect of Radiation in Immunologically Cold Head and Neck Squamous Cell Carcinoma

Jin, W. J., Erbe, A. K., Schwarz, C. N., Jaquish, A. A., Anderson, B. R., Sriramaneni, R. N., Jagodinsky, J. C., Bates, A. M., Clark, P. A., Le, T. Q. H., et al. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.591139 · Cited by 41 · see citing works

Clinical and Preclinical Outcomes of Combining Targeted Therapy With Radiotherapy

Elbanna, M., Chowdhury, N. N., Rhome, R. M., & Fishel, M. L. (2021) · Frontiers in Oncology · doi:10.3389/fonc.2021.749496 · Cited by 39 · see citing works

Opportunities and challenges in combining immunotherapy and radiotherapy in head and neck cancers

Wong, K. C. W., Johnson, D., Hui, E. P., Lam, R. C. T., Ma, B. B. Y., & Chan, A. T. �. (2022) · Cancer Treatment Reviews · doi:10.1016/j.ctrv.2022.102361 · Cited by 39 · see citing works

Radiotherapy and Immunotherapy Combinations in the Treatment of Patients with Metastatic Disease: Current Status and Future Focus

Turchan, W. T., Pitroda, S. P., & Weichselbaum, R. R. (2021) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-21-0145 · Cited by 37 · see citing works

Synergizing radiotherapy and immunotherapy: Current challenges and strategies for optimization

Rajeev-Kumar, G., & Pitroda, S. P. (2022) · Neoplasia · doi:10.1016/j.neo.2022.100867 · Cited by 37 · see citing works

Advances in Targeted Therapy for the Treatment of Cervical Cancer

Watkins, D., Craig, D. J., Vellani, S. D., Hegazi, A., Fredrickson, K. J., Walter, A., Stanbery, L., & Nemunaitis, J. J. (2023) · Journal of Clinical Medicine · doi:10.3390/jcm12185992 · Cited by 37 · see citing works

Infliximab for treatment-refractory transverse myelitis following immune therapy and radiation

Chang, V. A., Simpson, D. R., Daniels, G. A., & Piccioni, D. E. (2018) · Journal for ImmunoTherapy of Cancer · doi:10.1186/s40425-018-0471-2 · Cited by 37 · see citing works

The current advances and future directions of PD-1/PD-L1 blockade in head and neck squamous cell carcinoma (HNSCC) in the era of immunotherapy

Chen, Y., Ding, X., Bai, X., Zhou, Z., Liu, Y., Zhang, X., Yu, J., & Hu, M. (2023) · International Immunopharmacology · doi:10.1016/j.intimp.2023.110329 · Cited by 37 · see citing works

Time to Debunk an Urban Myth? The “Abscopal Effect” With Radiation and Anti–PD-1

Seiwert, T. Y., & Kiess, A. P. (2020) · Journal of Clinical Oncology · doi:10.1200/jco.20.02046 · Cited by 37 · see citing works

FLT3L release by NK cells enhances response to radioimmunotherapy in preclinical models of HNSCC

Bickett, T. E., Knitz, M. M., Darragh, L., Bhatia, S., Court, B. V., Gadwa, J., Bhuvane, S., Piper, M., Nguyen, D., Tu, H., et al. (2021) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-21-0971 · Cited by 26 · see citing works

Overcoming Resistance to Immune Checkpoint Inhibitors in Head and Neck Squamous Cell Carcinomas

dos Santos, L. V., Abrahão, C. M., & William, W. N. (2021) · Frontiers in Oncology · doi:10.3389/fonc.2021.596290 · Cited by 35 · see citing works

Updates in combined approaches of radiotherapy and immune checkpoint inhibitors for the treatment of breast cancer

Jungles, K. M., Holcomb, E. A., Pearson, A. N., Jungles, K. R., Bishop, C. R., Pierce, L. J., Green, M. D., & Speers, C. W. (2022) · Frontiers in Oncology · doi:10.3389/fonc.2022.1022542 · Cited by 35 · see citing works

Overcoming the Impact of Hypoxia in Driving Radiotherapy Resistance in Head and Neck Squamous Cell Carcinoma

Hill, R. M., Rocha, S., & Parsons, J. L. (2022) · Cancers · doi:10.3390/cancers14174130 · Cited by 33 · see citing works

Antitumor Immune Response Triggered by Metal-Based Photosensitizers for Photodynamic Therapy: Where Are We?

Jung, A. C., Moinard‐Butot, F., Thibaudeau, C., Gasser, G., & Gaiddon, C. (2021) · Pharmaceutics · doi:10.3390/pharmaceutics13111788 · Cited by 33 · see citing works

Recent Research on Combination of Radiotherapy with Targeted Therapy or Immunotherapy in Head and Neck Squamous Cell Carcinoma: A Review for Radiation Oncologists

Xing, D. T., Khor, R., Gan, H. K., Wada, M., Ermongkonchai, T., & Ng, S. P. (2021) · Cancers · doi:10.3390/cancers13225716 · Cited by 33 · see citing works

A Pilot Study of Durvalumab (MEDI4736) with Tremelimumab in Combination with Image-Guided Stereotactic Body Radiotherapy in the Treatment of Metastatic Anaplastic Thyroid Cancer

Lee, N. Y., Riaz, N., Wu, V., Brinkman, T., Tsai, C. J., Zhi, W., Fetten, J. V., Ho, A. L., Wong, R. J., Ghossein, R. A., et al. (2022) · Thyroid · doi:10.1089/thy.2022.0050 · Cited by 33 · see citing works

Oligometastatic Head and Neck Cancer: Challenges and Perspectives

Bahig, H., Huang, S. H., & O’Sullivan, B. (2022) · Cancers · doi:10.3390/cancers14163894 · Cited by 33 · see citing works

Enhancing therapeutic anti-cancer responses by combining immune checkpoint and tyrosine kinase inhibition

Daly, R. J., Scott, A. M., Klein, O., & Ernst, M. (2022) · Molecular Cancer · doi:10.1186/s12943-022-01656-z · Cited by 33 · see citing works

The Evolving Interplay of SBRT and the Immune System, along with Future Directions in the Field

Miljanic, M., Montalvo, S. K., Aliru, M. L., Song, T., Leon-Camarena, M., Innella, K., Vujovic, D., Komaki, R. R., & Iyengar, P. (2022) · Cancers · doi:10.3390/cancers14184530 · Cited by 31 · see citing works

Tumor-Targeted Nonablative Radiation Promotes Solid Tumor CAR T-cell Therapy Efficacy

Quach, H. T., Skovgard, M. S., Villena‐Vargas, J., Bellis, R. Y., Chintala, N. K., Amador-Molina, A., Bai, Y., Banerjee, S., Saini, J. K., Xiong, Y., et al. (2023) · Cancer Immunology Research · doi:10.1158/2326-6066.cir-22-0840 · Cited by 29 · see citing works

Beyond success: unveiling the hidden potential of radiotherapy and immunotherapy in solid tumors

Wu, Y., Yi, M., Niu, M., Zhou, B., Mei, Q., & Wu, K. (2024) · 癌症：英文版 · doi:10.1002/cac2.12576 · Cited by 29 · see citing works

Treatment Strategies for Oligometastatic Breast Cancer

Nesbit, E. G., Donnelly, E. D., & Strauss, J. B. (2021) · Current Treatment Options in Oncology · doi:10.1007/s11864-021-00889-2 · Cited by 30 · see citing works

Safety and Tolerability of Metastasis-Directed Radiation Therapy in the Era of Evolving Systemic, Immune, and Targeted Therapies

Guimond, E., Tsai, C. J., Hosni, A., O'Kane, G. M., Yang, J. T., & Barry, A. S. (2022) · Advances in Radiation Oncology · doi:10.1016/j.adro.2022.101022 · Cited by 30 · see citing works

Overview of the synergistic use of radiotherapy and immunotherapy in cancer treatment: current challenges and scopes of improvement

Colciago, R. R., Fischetti, I., Giandini, C., Rocca, E. L., Tiziana Rancati, T., Mateo, A. R., Colombo, M. P., Lozza, L., Chiodoni, C., Jachetti, E., et al. (2023) · Expert Review of Anticancer Therapy · doi:10.1080/14737140.2023.2173175 · Cited by 30 · see citing works

Integrating radiation therapy with targeted treatments for breast cancer: From bench to bedside

Meattini, I., Livi, L., Lorito, N., Becherini, C., Bacci, M., Visani, L., Fozza, A., Belgioia, L., Loi, M., Mangoni, M., et al. (2022) · Cancer Treatment Reviews · doi:10.1016/j.ctrv.2022.102417 · Cited by 30 · see citing works

Top Ten Lessons Learned from Trials in Oligometastatic Cancers

Tan, V. S., & Palma, D. A. (2022) · Cancer Research and Treatment · doi:10.4143/crt.2022.1460 · Cited by 29 · see citing works

Camrelizumab-based induction chemoimmunotherapy in locally advanced stage hypopharyngeal carcinoma: phase II clinical trial

Gong, H., Tian, S., Ding, H., Tao, L., Wang, L., Wang, J., Wang, T., Yuan, X., Heng, Y., Zhang, M., et al. (2024) · Nature Communications · doi:10.1038/s41467-024-49121-3 · Cited by 28 · see citing works

Targeted Therapies and Immune-Checkpoint Inhibition in Head and Neck Squamous Cell Carcinoma: Where Do We Stand Today and Where to Go?

von der Grün, J., Rödel, F., Brandts, C., Fokas, E., Gückenberger, M., Rödel, C. M., & Balermpas, P. (2019) · Cancers · doi:10.3390/cancers11040472 · Cited by 28 · see citing works

Radiotherapy in the Era of Immunotherapy With a Focus on Non-Small-Cell Lung Cancer: Time to Revisit Ancient Dogmas?

Khalifa, J., Mazières, J., Gomez‐Roca, C., Ayyoub, M., & Moyal, E. C. (2021) · Frontiers in Oncology · doi:10.3389/fonc.2021.662236 · Cited by 28 · see citing works

Neoadjuvant immunotherapy is reshaping cancer management across multiple tumour types: The future is now!

Maio, M., Blank, C. U., Necchi, A., Giacomo, A. M. D., Ibrahim, R. A., Lahn, M., Fox, B. A., Bell, R. B., Tortora, G., & Eggermont, A. M. M. (2021) · European Journal of Cancer · doi:10.1016/j.ejca.2021.04.035 · Cited by 28 · see citing works

Real-Life Study of the Benefit of Concomitant Radiotherapy with Cemiplimab in Advanced Cutaneous Squamous Cell Carcinoma (cSCC): A Retrospective Cohort Study

Bailly-Caillé, B., Kottler, D., Morello, R., Lecornu, M., Kao, W., Meyer, E., Dompmartin, A., & L'Orphelin, J. ‐. (2023) · Cancers · doi:10.3390/cancers15020495 · Cited by 28 · see citing works

Combination radiation and αPD-L1 enhance tumor control by stimulating CD8+ PD-1+ TCF-1+ T cells in the tumor-draining lymph node

Shen, Y., Connolly, E. C., Aiello, M., Zhou, C., Chappa, P., Song, H., Tippitak, P., Clark, T. Y., Cardenas, M. A., Prokhnevska, N., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-58510-1 · Cited by 27 · see citing works

Challenges in Combining Immunotherapy with Radiotherapy in Recurrent/Metastatic Head and Neck Cancer

Plavc, G., Jesenko, T., Oražem, M., & Strojan, P. (2020) · Cancers · doi:10.3390/cancers12113197 · Cited by 26 · see citing works

A phase II randomized trial of nivolumab with stereotactic body radiotherapy (SBRT) versus nivolumab alone in metastatic (M1) head and neck squamous cell carcinoma (HNSCC).

McBride, S. M., Sherman, E. J., Tsai, C. J., Baxi, S. S., Aghalar, J., Eng, J., Zhi, W. I., McFarland, D. C., Michel, L. S., Spielsinger, D., et al. (2018) · Journal of Clinical Oncology · doi:10.1200/jco.2018.36.15_suppl.6009 · Cited by 61 · see citing works

CAMRESBRT: Randomized Phase II Trial of Camrelizumab with Stereotactic Body Radiotherapy vs. Camrelizumab Alone in Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma

Lei, Q., Wang, Y., Sui, J.-D., Luo, Q., Jin, F., Long, B., Shu, X., Li, S., Huang, L., Zhong, M., et al. (2022) · International Journal of Radiation Oncology*Biology*Physics · doi:10.1016/j.ijrobp.2022.07.1302

The Abscopal Effect in Head-and-Neck Squamous Cell Carcinoma Treated with Radiotherapy and Nivolumab: A Case Report and Literature Review

Forner, D. W. A., Horwich, P., Trites, J. R. B., Hollenhorst, H., Bullock, M. J., & Lamond, N. W. D. (2020) · Current Oncology · doi:10.3747/co.27.6687 · Cited by 25 · see citing works

A randomized phase II study of chemoradiation (CRT) +/- nivolumab (Nivo) with sequential safety evaluations of Nivo +/- lirilumab (Liri) or ipilumumab (Ipi) concomitant with (C) RT in intermediate (IR) and high-risk (HR) head and neck squamous cell carcinoma (HNSCC) (RTOG 3504, NCT02764593).

Gillison, M. L., Ferris, R. L., Zhang, Q., Colevas, A. D., Mell, L. K., Kong, C. S., Jordan, R. C., Moore, K. L., Truong, M. T., Kirsch, C., et al. (2017) · Journal of Clinical Oncology · doi:10.1200/jco.2017.35.15_suppl.tps6097 · Cited by 4 · see citing works

Safety Evaluation of Nivolumab Concomitant With Platinum-Based Chemoradiation therapy for Intermediate and High-Risk Local-Regionally Advanced Head and Neck Squamous Cell Carcinoma: RTOG Foundation 3504

Gillison, M. L., Ferris, R. L., Zhang, Q., Colevas, A. D., Mell, L. K., Kirsch, C., Moore, K. L., Truong, M. T., Kong, C. S., Jordan, R., et al. (2018) · International Journal of Radiation Oncology*Biology*Physics · doi:10.1016/j.ijrobp.2017.12.022 · Cited by 11 · see citing works