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Johnstone, R. W., Wu, W., Greenway, A. L., & Trapani, J. A. (2000) · Oncogene · doi:10.1038/sj.onc.1204005 · Cited by 109 · see citing works

Suppression of Type I Interferon Signaling Overcomes Oncogene-Induced Senescence and Mediates Melanoma Development and Progression

Katlinskaya, Y. V., Katlinski, K. V., Yu, Q., Ortiz, A., Beiting, D. P., Brice, A., Davar, D., Sanders, C., Kirkwood, J. M., Rui, H., et al. (2016) · Cell Reports · doi:10.1016/j.celrep.2016.03.006 · Cited by 108 · see citing works

Interferon-inducible p200-family protein IFI16, an innate immune sensor for cytosolic and nuclear double-stranded DNA: Regulation of subcellular localization

Veeranki, S., & Choubey, D. (2011) · Molecular Immunology · doi:10.1016/j.molimm.2011.11.004 · Cited by 105 · see citing works

Adjuvant-Mediated Tumor Regression and Tumor-Specific Cytotoxic Response Are Impaired in MyD88-Deficient Mice

Akazawa, T., Masuda, H., Saeki, Y., Matsumoto, M., Takeda, K., Tsujimura, K., Kuzushima, K., Takahashi, T., Azuma, I., Akira, S., et al. (2004) · Cancer Research · doi:10.1158/0008-5472.can-03-1518 · Cited by 105 · see citing works

Requirement of IFI16 for the Maximal Activation of p53 Induced by Ionizing Radiation

Fujiuchi, N., Aglipay, J. A., Ohtsuka, T., Maehara, N., Sahin, F., Su, G. H., Lee, S. W., & Ouchi, T. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m400344200 · Cited by 102 · see citing works

A novel gene constitutively expressed in human lymphoid cells is inducible with interferon-? in myeloid cells

Trapani, J. A., Browne, K. A., Dawson, M. J., Ramsay, R. G., Eddy, R. L., Shows, T. B., White, P., & Dupont, B. (1992) · Immunogenetics · doi:10.1007/bf00218044 · Cited by 92 · see citing works

The innate immune sensor IFI16 recognizes foreign DNA in the nucleus by scanning along the duplex

Stratmann, S. A., Morrone, S. R., van Oijen, A. M., & Sohn, J. (2015) · eLife · doi:10.7554/elife.11721 · Cited by 88 · see citing works

IFI16, an amplifier of DNA-damage response: Role in cellular senescence and aging-associated inflammatory diseases

Choubey, D., & Panchanathan, R. (2016) · Ageing Research Reviews · doi:10.1016/j.arr.2016.04.002 · Cited by 82 · see citing works

Cyclic‐di‐GMP and cyclic‐di‐AMP activate the NLRP3 inflammasome

Sater, A. A. A., Tattoli, I., Jin, L., Grajkowski, A., Levi, A., Koller, B. H., Allen, I. C., Beaucage, S. L., Fitzgerald, K. A., Ting, J. P. ‐., et al. (2013) · EMBO Reports · doi:10.1038/embor.2013.132 · Cited by 81 · see citing works

Three prime exonuclease I (TREX1) is Fos/AP-1 regulated by genotoxic stress and protects against ultraviolet light and benzo(a)pyrene-induced DNA damage

Christmann, M., Tomicic, M. T., Aasland, D., Berdelle, N., & Kaina, B. (2010) · Nucleic Acids Research · doi:10.1093/nar/gkq455 · Cited by 76 · see citing works

A cell-based high throughput screening assay for the discovery of cGAS-STING pathway agonists

Liu, B., Tang, L., Zhang, X., Ma, J., Sehgal, M., Cheng, J., Zhang, X., Zhou, Y., Du, Y., Kulp, J. L., et al. (2017) · Antiviral Research · doi:10.1016/j.antiviral.2017.10.001 · Cited by 74 · see citing works

Familial Chilblain Lupus Due to a Novel Mutation in the Exonuclease III Domain of 3′ Repair Exonuclease 1 (TREX1)

Günther, C., Berndt, N., Wolf, C., & Lee‐Kirsch, M. A. (2014) · JAMA Dermatology · doi:10.1001/jamadermatol.2014.3438 · Cited by 71 · see citing works

Blocking β-catenin binding to the ZBP1 promoter represses ZBP1 expression, leading to increased proliferation and migration of metastatic breast-cancer cells

Gu, W., Pan, F., & Singer, R. H. (2009) · Journal of Cell Science · doi:10.1242/jcs.045278 · Cited by 68 · see citing works

DNA-Sensing and Nuclease Gene Expressions as Markers for Colorectal Cancer Progression

Yang, C., Huang, H., Chang, Y., Lin, C., Lai, I., & Chang, J. (2016) · Oncology · doi:10.1159/000452281 · Cited by 67 · see citing works

DNA binding to proteolytically activated TLR9 is sequence‐independent and enhanced by DNA curvature

Li, Y., Berke, I. C., & Modis, Y. (2011) · The EMBO Journal · doi:10.1038/emboj.2011.441 · Cited by 66 · see citing works

Histone H2B-IFI16 Recognition of Nuclear Herpesviral Genome Induces Cytoplasmic Interferon-β Responses

Iqbal, J., Ansari, M. A., Kumar, B., Dutta, D., Roy, A., Leela, C., Pisano, G. C., Dutta, S., Vahedi, S., Veettil, M. V., et al. (2016) · PLoS Pathogens · doi:10.1371/journal.ppat.1005967 · Cited by 58 · see citing works

Trial Watch: Immunostimulation with recombinant cytokines for cancer therapy

García-Martínez, E., Smith, M. M., Buqué, A., Aranda, F., de la Peña, F. A., Rubio, A. I., Cánovas, M. S., Conesa, M. A. V., Fucikova, J. P., Špíšek, R., et al. (2018) · OncoImmunology · doi:10.1080/2162402x.2018.1433982 · Cited by 56 · see citing works

Induction of Noxa-Mediated Apoptosis by Modified Vaccinia Virus Ankara Depends on Viral Recognition by Cytosolic Helicases, Leading to IRF-3/IFN-β-Dependent Induction of Pro-Apoptotic Noxa

Ferrer, P. E., Potthoff, S., Kirschnek, S., Gasteiger, G., Kastenmüller, W., Ludwig, H., Paschen, S. A., Villunger, A., Sutter, G., Drexler, I., et al. (2011) · PLoS Pathogens · doi:10.1371/journal.ppat.1002083 · Cited by 54 · see citing works

ZBP1 enhances cell polarity and reduces chemotaxis

Lapidus, K. A. B., Wyckoff, J. B., Mouneimne, G., Lorenz, M., Soon, L., Condeelis, J. S., & Singer, R. H. (2007) · Journal of Cell Science · doi:10.1242/jcs.000638 · Cited by 48 · see citing works

The proapoptotic activity of the Interferon-inducible gene IFI16 provides new insights into its etiopathogenetic role in autoimmunity

Gugliesi, F., Andrea, M. D., Mondini, M., Cappello, P., Giovarelli, M., Shoenfeld, Y., Meroni, P. L., Gariglio, M., & Landolfo, S. (2010) · Journal of Autoimmunity · doi:10.1016/j.jaut.2010.04.001 · Cited by 45 · see citing works

Myeloid Differentiation Factor 88 Is Required for Cross-Priming In Vivo

Palliser, D., Ploegh, H. L., & Boes, M. L. (2004) · The Journal of Immunology · doi:10.4049/jimmunol.172.6.3415 · Cited by 44 · see citing works

Clinical Development of Vascular Disrupting Agents: What Lessons Can We Learn From ASA404?

LoRusso, P. M., Boerner, S. A., & Hunsberger, S. (2011) · Journal of Clinical Oncology · doi:10.1200/jco.2011.36.1311 · Cited by 43 · see citing works

Human three prime exonuclease TREX1 is induced by genotoxic stress and involved in protection of glioma and melanoma cells to anticancer drugs

Tomicic, M. T., Aasland, D., Nikolova, T., Kaina, B., & Christmann, M. (2013) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2013.03.029 · Cited by 33 · see citing works

Expression and clinical significance of absent in melanoma 2 in colorectal cancer

Zhang, Z., Dong, X., Yang, X., Wan, D., Sun, L., Gu, M., Li, M., Zhu, Z. G., Wang, J., Shang, Z., et al. (2017) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2017.07.161 · Cited by 19 · see citing works

Inducible activation of IFI 16 results in suppression of telomerase activity, growth suppression and induction of cellular senescence

Clarke, C. J. P., Hii, L. L., Bolden, J. E., & Johnstone, R. W. (2009) · Journal of Cellular Biochemistry · doi:10.1002/jcb.22386 · Cited by 18 · see citing works

AGS, SLE, and RNASEH2 mutations: translating insights into therapeutic advances

Pendergraft, W. F., & Means, T. K. (2014) · Journal of Clinical Investigation · doi:10.1172/jci78533 · Cited by 16 · see citing works

Cytosolic Double-Stranded DNA Induces Nonnecroptotic Programmed Cell Death in Trophoblasts via IFI16

Chu, X. T., Chen, W., Li, N., Hu, X.-Z., Du, C., Yu, S.-X., Zhou, M., Zhang, X.-J., Jiang, G.-M., Han, W., et al. (2014) · The Journal of Infectious Diseases · doi:10.1093/infdis/jiu272 · Cited by 16 · see citing works

Cridanimod and progestin therapy in hormone-resistant endometrial cancer.

Carlson, M. J., Geest, K. D., Wang, X., Leslie, K. K., & Dai, D. D. (2013) · Journal of Clinical Oncology · doi:10.1200/jco.2013.31.15_suppl.5597 · Cited by 3 · see citing works

Regulation of apoptosis in health and disease: the balancing act of BCL-2 family proteins

Singh, R., Letai, A., & Sarosiek, K. (2019) · Nature Reviews Molecular Cell Biology · doi:10.1038/s41580-018-0089-8 · Cited by 2,111 · see citing works

Autophagy in major human diseases

Klionsky, D. J., Petroni, G., Amaravadi, R. K., Baehrecke, E. H., Ballabio, A., Boya, P., Bravo‐San Pedro, J. M., Cadwell, K., Cecconi, F., Choi, A. M. K., et al. (2021) · The EMBO Journal · doi:10.15252/embj.2021108863 · Cited by 1,585 · see citing works

Immunogenic cell stress and death

Kroemer, G., Galassi, C., Zitvogel, L., & Galluzzi, L. (2022) · Nature Immunology · doi:10.1038/s41590-022-01132-2 · Cited by 1,353 · see citing works

Immunostimulation with chemotherapy in the era of immune checkpoint inhibitors

Galluzzi, L., Humeau, J., Buqué, A., Zitvogel, L., & Kroemer, G. (2020) · Nature Reviews Clinical Oncology · doi:10.1038/s41571-020-0413-z · Cited by 1,349 · see citing works

Consensus guidelines for the definition, detection and interpretation of immunogenic cell death

Galluzzi, L., Vitale, I., Warren, S., Adjemian, S., Agostinis, P., Buqué, A., Chan, T. A.-T., Coukos, G., Demaria, S., Deutsch, É., et al. (2020) · Journal for ImmunoTherapy of Cancer · doi:10.1136/jitc-2019-000337 · Cited by 1,151 · see citing works

Detection of immunogenic cell death and its relevance for cancer therapy

Fucikova, J., Kepp, O., Kasikova, L., Petroni, G., Yamazaki, T., Liu, P., Zhao, L., Spisek, R., Kroemer, G., & Galluzzi, L. (2020) · Cell Death & Disease · doi:10.1038/s41419-020-03221-2 · Cited by 1,138 · see citing works

Mitochondrial control of inflammation

Marchi, S., Guilbaud, E., Tait, S. W. G., Yamazaki, T., & Galluzzi, L. (2023) · Nature Reviews Immunology · doi:10.1038/s41577-022-00760-x · Cited by 1,027 · see citing works

The hallmarks of cancer immune evasion

Galassi, C., Chan, T. A.-T., Vitale, I., & Galluzzi, L. (2024) · Cancer Cell · doi:10.1016/j.ccell.2024.09.010 · Cited by 595 · see citing works

Activating cGAS-STING pathway for the optimal effect of cancer immunotherapy

Li, A., Yi, M., Qin, S., Song, Y., Chu, Q., & Wu, K. (2019) · Journal of Hematology & Oncology · doi:10.1186/s13045-019-0721-x · Cited by 413 · see citing works

Randomized Phase II Trial of Nivolumab With Stereotactic Body Radiotherapy Versus Nivolumab Alone in Metastatic Head and Neck Squamous Cell Carcinoma

McBride, S., Sherman, E., Tsai, C. J., Baxi, S., Aghalar, J., Eng, J., Zhi, W. I., McFarland, D., Michel, L. S., Young, R., et al. (2021) · Journal of Clinical Oncology · doi:10.1200/jco.20.00290 · Cited by 402 · see citing works

Immunogenic cell death in cancer: targeting necroptosis to induce antitumour immunity

Meier, P., Legrand, A. J., Adam, D., & Silke, J. (2024) · Nature reviews. Cancer · doi:10.1038/s41568-024-00674-x · Cited by 405 · see citing works

Immunological impact of cell death signaling driven by radiation on the tumor microenvironment

Rodriguez-Ruiz, M. E., Vitale, I., Harrington, K. J., Melero, I., & Galluzzi, L. (2020) · Nature Immunology · doi:10.1038/s41590-019-0561-4 · Cited by 385 · see citing works

Chemical and Biomolecular Strategies for STING Pathway Activation in Cancer Immunotherapy

Garland, K. M., Sheehy, T. L., & Wilson, J. T. (2022) · Chemical Reviews · doi:10.1021/acs.chemrev.1c00750 · Cited by 368 · see citing works

Mutant p53 Suppresses Innate Immune Signaling to Promote Tumorigenesis

Ghosh, M., Saha, S., Bettke, J. A., Nagar, R., Parrales, A., Iwakuma, T., van der Velden, A. W. M., & Martinez, L. A. (2020) · Cancer Cell · doi:10.1016/j.ccell.2021.01.003 · Cited by 344 · see citing works

Cancer cell metabolism and antitumour immunity

Martino, M. D., Rathmell, J. C., Galluzzi, L., & Vanpouille‐Box, C. (2024) · Nature reviews. Immunology · doi:10.1038/s41577-024-01026-4 · Cited by 363 · see citing works

Comprehensive elaboration of the cGAS-STING signaling axis in cancer development and immunotherapy

Zheng, J., Mo, J., Zhu, T., Zhuo, W., Yi, Y., Hu, S., Yin, J., Zhang, W., Zhou, H., & Liu, Z. (2020) · Molecular Cancer · doi:10.1186/s12943-020-01250-1 · Cited by 332 · see citing works

Cancer-Cell-Intrinsic cGAS Expression Mediates Tumor Immunogenicity

Schadt, L., Sparano, C., Schweiger, N. A., Siliņa, K., Cecconi, V., Lucchiari, G., Yagita∥, H., Guggisberg, E., Saba, S., Naščáková, Z., et al. (2019) · Cell Reports · doi:10.1016/j.celrep.2019.09.065 · Cited by 290 · see citing works

Trial watch: STING agonists in cancer therapy

Le Naour, J., Zitvogel, L., Galluzzi, L., Vacchelli, E., & Kroemer, G. (2020) · OncoImmunology · doi:10.1080/2162402x.2020.1777624 · Cited by 289 · see citing works

Trial watch: TLR3 agonists in cancer therapy

Le Naour, J., Galluzzi, L., Zitvogel, L., Kroemer, G., & Vacchelli, E. (2020) · OncoImmunology · doi:10.1080/2162402x.2020.1771143 · Cited by 239 · see citing works

Mitophagy in tumorigenesis and metastasis

Poole, L. P., & Macleod, K. F. (2021) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-021-03774-1 · Cited by 250 · see citing works

Lysine catabolism reprograms tumour immunity through histone crotonylation

Yuan, H., Wu, X., Wu, Q., Chatoff, A. G., Megill, E., Gao, J., Huang, T., Duan, T., Yang, K., Jin, C., et al. (2023) · Nature · doi:10.1038/s41586-023-06061-0 · Cited by 241 · see citing works

Targeting innate immune pathways for cancer immunotherapy

Cao, L. L., & Kagan, J. C. (2023) · Immunity · doi:10.1016/j.immuni.2023.07.018 · Cited by 224 · see citing works

Immunomodulation by targeted anticancer agents

Petroni, G., Buqué, A., Zitvogel, L., Kroemer, G., & Galluzzi, L. (2021) · Cancer Cell · doi:10.1016/j.ccell.2020.11.009 · Cited by 212 · see citing works

Optimising efficacy and reducing toxicity of anticancer radioimmunotherapy

Deutsch, É., Chargari, C., Galluzzi, L., & Kroemer, G. (2019) · The Lancet Oncology · doi:10.1016/s1470-2045(19)30171-8 · Cited by 210 · see citing works

Senolytics and senostatics as adjuvant tumour therapy

Short, S. C., Fielder, E., Miwa, S., & von Zglinicki, T. (2019) · EBioMedicine · doi:10.1016/j.ebiom.2019.01.056 · Cited by 201 · see citing works

The two sides of chromosomal instability: drivers and brakes in cancer

Hosea, R., Hillary, S., Naqvi, S., Wu, S., & Kasim, V. (2024) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-024-01767-7 · Cited by 205 · see citing works

BRCA2 abrogation triggers innate immune responses potentiated by treatment with PARP inhibitors

Reisländer, T., Lombardi, E. P., Groelly, F. J., Miar, A., Porru, M., Vito, S. D., Wright, B., Lockstone, H. E., Biroccio, A., Harris, A. L., et al. (2019) · Nature Communications · doi:10.1038/s41467-019-11048-5 · Cited by 192 · see citing works

NK cells and solid tumors: therapeutic potential and persisting obstacles

Tong, L., Jiménez‐Cortegana, C., Tay, A. H. M., Wickström, S. L., Galluzzi, L., & Lundqvist, A. (2022) · Molecular Cancer · doi:10.1186/s12943-022-01672-z · Cited by 193 · see citing works

Trial watch: IDO inhibitors in cancer therapy

Naour, J. L., Galluzzi, L., Zitvogel, L., Kroemer, G., & Vacchelli, E. (2020) · OncoImmunology · doi:10.1080/2162402x.2020.1777625 · Cited by 188 · see citing works

Pharmacological modulation of nucleic acid sensors - therapeutic potential and persisting obstacles

Vanpouille-Box, C., Hoffmann, J. A., & Galluzzi, L. (2019) · Nature Reviews Drug Discovery · doi:10.1038/s41573-019-0043-2 · Cited by 183 · see citing works

Targeting oncogene and non-oncogene addiction to inflame the tumour microenvironment

Petroni, G., Buqué, A., Coussens, L. M., & Galluzzi, L. (2022) · Nature Reviews Drug Discovery · doi:10.1038/s41573-022-00415-5 · Cited by 162 · see citing works

Revisiting the Radiobiology of Targeted Alpha Therapy

Pouget, J., & Constanzo, J. (2021) · Frontiers in Medicine · doi:10.3389/fmed.2021.692436 · Cited by 149 · see citing works

Apoptotic caspases inhibit abscopal responses to radiation and identify a new prognostic biomarker for breast cancer patients

Rodriguez-Ruiz, M. E., Buqué, A., Hensler, M., Chen, J., Bloy, N., Petroni, G., Sato, A., Yamazaki, T., Fucikova, J., & Galluzzi, L. (2019) · OncoImmunology · doi:10.1080/2162402x.2019.1655964 · Cited by 147 · see citing works

Trial watch: dendritic cell vaccination for cancer immunotherapy

Sprooten, J., Ceusters, J., Coosemans, A., Agostinis, P., Vleeschouwer, S. D., Zitvogel, L., Kroemer, G., Galluzzi, L., & Garg, A. D. (2019) · OncoImmunology · doi:10.1080/2162402x.2019.1638212 · Cited by 148 · see citing works

PARP1 inhibitors trigger innate immunity via PARP1 trapping-induced DNA damage response

Kim, C., Wang, X.-D., & Yu, Y. (2020) · eLife · doi:10.7554/elife.60637 · Cited by 136 · see citing works

Anti-tumor immunity in mismatch repair-deficient colorectal cancers requires type I IFN–driven CCL5 and CXCL10

Mowat, C., Mosley, S. R., Namdar, A., Schiller, D., & Baker, K. (2021) · The Journal of Experimental Medicine · doi:10.1084/jem.20210108 · Cited by 134 · see citing works

Temozolomide Treatment Alters Mismatch Repair and Boosts Mutational Burden in Tumor and Blood of Colorectal Cancer Patients

Crisafulli, G., Bianchi, A. S., Lazzari, L., Pietrantonio, F., Amatu, A., Macagno, M., Barault, L., Cassingena, A., Bartolini, A., Luraghi, P., et al. (2022) · Cancer Discovery · doi:10.1158/2159-8290.cd-21-1434 · Cited by 134 · see citing works

Type I interferon and cancer

Holíček, P., Guilbaud, E., Klapp, V., Truxová, I., Špíšek, R., Galluzzi, L., & Fucikova, J. P. (2023) · Immunological Reviews · doi:10.1111/imr.13272 · Cited by 138 · see citing works

Combining Radiotherapy and Immunotherapy in Lung Cancer: Can We Expect Limitations Due to Altered Normal Tissue Toxicity?

Wirsdörfer, F., de Leve, S., & Jendrossek, V. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms20010024 · Cited by 132 · see citing works

Type I interferons and dendritic cells in cancer immunotherapy

(2019) · International Review of Cell and Molecular Biology · doi:10.1016/bs.ircmb.2019.06.001 · Cited by 124 · see citing works

Machete identifies interferon-encompassing chromosome 9p21.3 deletions as mediators of immune evasion and metastasis

Barriga, F. M., Tsanov, K. M., Ho, Y.-J., Sohail, N., Zhang, A., Baslan, T., Wuest, A. N., Del Priore, I., Meškauskaitė, B., Livshits, G., et al. (2022) · Nature Cancer · doi:10.1038/s43018-022-00443-5 · Cited by 125 · see citing works

Immunosurveillance in clinical cancer management

Kroemer, G., Chan, T. A.-T., Eggermont, A. M. M., & Galluzzi, L. (2023) · CA A Cancer Journal for Clinicians · doi:10.3322/caac.21818 · Cited by 128 · see citing works

The Remarkable Plasticity of Macrophages: A Chance to Fight Cancer

Bercovici, N., Guérin, M., Trautmann, A., & Donnadieu, E. (2019) · Frontiers in Immunology · doi:10.3389/fimmu.2019.01563 · Cited by 94 · see citing works

Clinical applications of fibroblast activation protein inhibitor positron emission tomography (FAPI-PET)

Mori, Y., Novruzov, E., Schmitt, D. R., Cardinale, J., Watabe, T., Choyke, P. L., Alavi, A. A., Haberkorn, U., & Giesel, F. L. (2024) · npj Imaging · doi:10.1038/s44303-024-00053-z · Cited by 122 · see citing works

Exosome DNA: Critical regulator of tumor immunity and a diagnostic biomarker

Sharma, A., & Johnson, A. (2019) · Journal of Cellular Physiology · doi:10.1002/jcp.29153 · Cited by 120 · see citing works

Identification and Analyses of Extra-Cranial and Cranial Rhabdoid Tumor Molecular Subgroups Reveal Tumors with Cytotoxic T Cell Infiltration

Chun, H.-J. E., Johann, P. D., Milne, K., Zapatka, M., Büllesbach, A., Ishaque, N., Iskar, M., Erkek, S., Wei, L. L., Tessier‐Cloutier, B., et al. (2019) · Cell Reports · doi:10.1016/j.celrep.2019.10.013 · Cited by 116 · see citing works

FBXO44 promotes DNA replication-coupled repetitive element silencing in cancer cells

Shen, J. Z., Qiu, Z., Wu, Q., Finlay, D., Garcia, G., Sun, D., Rantala, J., Barshop, W., Hope, J. L., Gimple, R. C., et al. (2021) · Cell · doi:10.1016/j.cell.2020.11.042 · Cited by 113 · see citing works

5‐Fluorouracil efficacy requires anti‐tumor immunity triggered by cancer‐cell‐intrinsic STING

Tian, J., Zhang, D., Kurbatov, V., Wang, Q., Wang, Y., Fang, D., Wu, L., Bosenberg, M., Muzumdar, M. D., Khan, S. A., et al. (2021) · The EMBO Journal · doi:10.15252/embj.2020106065 · Cited by 110 · see citing works

The tumor suppressor kinase DAPK3 drives tumor-intrinsic immunity through the STING–IFN-β pathway

Takahashi, M., Lio, C. J., Campeau, A., Steger, M., Ay, F., Mann, M., Gonzalez, D. J., Jain, M., & Sharma, S. (2021) · Nature Immunology · doi:10.1038/s41590-021-00896-3 · Cited by 113 · see citing works

The DNA Damage Response and Inflammation in Cancer

Klapp, V., Álvarez-Abril, B., Leuzzi, G., Kroemer, G., Ciccia, A., & Galluzzi, L. (2023) · Cancer Discovery · doi:10.1158/2159-8290.cd-22-1220 · Cited by 110 · see citing works

Chemotherapy-induced senescence, an adaptive mechanism driving resistance and tumor heterogeneity

Guillon, J., Petit, C., Toutain, B., Guette, C., Lelièvre, E., & Coqueret, O. (2019) · Cell Cycle · doi:10.1080/15384101.2019.1652047 · Cited by 102 · see citing works

Ribosome biogenesis restricts innate immune responses to virus infection and DNA

Bianco, C., & Mohr, I. (2019) · eLife · doi:10.7554/elife.49551 · Cited by 101 · see citing works

Interfaces between cellular responses to DNA damage and cancer immunotherapyPreprint

Pilger, D., Seymour, L. W., & Jackson, S. P. (2021) · Genes & Development · doi:10.1101/gad.348314.121 · Cited by 94 · see citing works

Mutational and Antigenic Landscape in Tumor Progression and Cancer Immunotherapy

Vitale, I., Sistigu, A., Manic, G., Rudqvist, N.-P., Trajanoski, Z., & Galluzzi, L. (2019) · Trends in Cell Biology · doi:10.1016/j.tcb.2019.01.003 · Cited by 94 · see citing works

SHP-2 and PD-1-SHP-2 signaling regulate myeloid cell differentiation and antitumor responses

Christofides, A., Katopodi, X.-L., Cao, C., Karagkouni, D., Aliazis, K., Yenyuwadee, S., Aksoylar, H., Pal, R., Mahmoud, M. A. A., Strauss, L., et al. (2022) · Nature Immunology · doi:10.1038/s41590-022-01385-x · Cited by 95 · see citing works

Properties and Application of Cell-Free DNA as a Clinical Biomarker

de Miranda, F. S., Baraúna, V. G., dos Santos, L., Costa, G. G. D., Vassallo, P. F., & Campos, L. C. G. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22179110 · Cited by 92 · see citing works

Extracorporeal photochemotherapy induces bona fide immunogenic cell death

Tatsuno, K., Yamazaki, T., Hanlon, D. J., Han, P., Robinson, E., Sobolev, O., Yurter, A., Rivera-Molina, F. E., Arshad, N., Edelson, R. L., et al. (2019) · Cell Death and Disease · doi:10.1038/s41419-019-1819-3 · Cited by 89 · see citing works

Type I interferons and endoplasmic reticulum stress in health and disease

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cGAS-STING pathway as a potential trigger of immunosenescence and inflammaging

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Mitophagy and Mitochondrial Dysfunction in Cancer

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Is There a Place for Immunotherapy for Metastatic Microsatellite Stable Colorectal Cancer?

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Is there a causal link between PTEN deficient tumors and immunosuppressive tumor microenvironment?

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Autophagy and cancer cell metabolism

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Calreticulin exposure on malignant blasts correlates with improved natural killer cell-mediated cytotoxicity in acute myeloid leukemia patients

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TREX1 – Apex predator of cytosolic DNA metabolism

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USP49 negatively regulates cellular antiviral responses via deconjugating K63-linked ubiquitination of MITA

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Exosomes as Powerful Engines in Cancer: Isolation, Characterization and Detection Techniques

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The interplay between the DNA damage response and ectonucleotidases modulates tumor response to therapy

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Considerations for the delivery of STING ligands in cancer immunotherapy

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cGAS/STING: novel perspectives of the classic pathway

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The cGAS/STING–TBK1–IRF Regulatory Axis Orchestrates a Primitive Interferon-Like Antiviral Mechanism in Oyster

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Intratumoral immunotherapy with STING agonist, ADU-S100, induces CD8+ T-Cell mediated anti-tumor immunity in an esophageal adenocarcinoma model

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The Yin and Yang of Type I IFNs in Cancer Promotion and Immune Activation

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PARP7-mediated ADP-ribosylation of FRA1 promotes cancer cell growth by repressing IRF1- and IRF3-dependent apoptosis

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Adding liposomal doxorubicin enhances the abscopal effect induced by radiation/αPD1 therapy depending on tumor cell mitochondrial DNA and cGAS/STING

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Platelets sequester extracellular DNA, capturing tumor-derived and free fetal DNA

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Refractoriness of STING therapy is relieved by AKT inhibitor through effective vascular disruption in tumour

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Current strategies employed in the manipulation of gene expression for clinical purposes

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Record‐High Ultrasound‐Sensitive NO Nanogenerators for Cascade Tumor Pyroptosis and Immunotherapy

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A next-generation STING agonist MSA-2: From mechanism to application

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DNA Associated with Circulating Exosomes as a Biomarker for Glioma

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Combined analysis and validation for DNA methylation and gene expression profiles associated with prostate cancer

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The primitive interferon-like system and its antiviral function in molluscs

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Trial Watch: combination of tyrosine kinase inhibitors (TKIs) and immunotherapy

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Genomic mediators of acquired resistance to immunotherapy in metastatic melanoma

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Interferon- and STING-independent induction of type I interferon stimulated genes during fractionated irradiation

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New insights into nucleic acid sensor AIM2: The potential benefit in targeted therapy for cancer

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The cGAS-STING Pathway in Hematopoiesis and Its Physiopathological Significance

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Detection and quantification of cytosolic DNA

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Sensing the Breaks: Cytosolic Chromatin in Senescence and Cancer

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Negative Regulation of Cytosolic Sensing of DNA

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Cloning and Characterization of Cytosolic DNA in Tumors

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DNA sensing and immune responses in cancer therapy

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