Comprehensive geriatric assessment for older patients with cancer
Abstract
PURPOSE: During the last decade, oncologists and geriatricians have begun to work together to integrate the principles of geriatrics into oncology care. The increasing use of a comprehensive geriatric assessment (CGA) is one example of this effort. A CGA includes an evaluation of an older individual's functional status, comorbid medical conditions, cognition, nutritional status, psychological state, and social support; and a review of the patient's medications. This article discusses recent advances on the use of a CGA in older patients with cancer. METHODS: In this article, we provide an update on the studies that address the domains of a geriatric assessment applied to the oncology patient, review the results of the first studies evaluating the use of a CGA in developing interventions to improve the care of older adults with cancer, and discuss future research directions. RESULTS: The evidence from recent studies demonstrates that a CGA can predict morbidity and mortality in older patients with cancer. Accumulating data show the benefits of incorporating a CGA in the evaluation of older patients with cancer. Prospective trials evaluating the utility of a CGA to guide interventions to improve the quality of cancer care in older adults are justified. CONCLUSION: Growing evidence demonstrates that the variables examined in a CGA can predict morbidity and mortality in older patients with cancer, and uncover problems relevant to cancer care that would otherwise go unrecognized.
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Comprehensive geriatric assessment can predict morbidity and mortality in elderly cancer patients.
“CGA can predict morbidity and mortality in elderly patients with cancer [75]”
From Metastatic non-small-cell lung cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up (2016) · cites this paper as [75]
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Self-citation
- Authors
- Extermann, M., & Hurria, A.
- Affiliations
- City Of Hope National Medical Center (US)
- Venue
- Journal of Clinical Oncology
- Published
- 2007-05-10
- Volume
- 25
- Issue
- 14
- Pages
- 1824-1831
- ISSN
- 0732-183X (ISSN-L)
- 1527-7755
- OpenAlex
- W2093679650
- Cited by
- 875
- References
- 83
- Citations by year
- 2026: 15 · 2025: 20 · 2024: 18 · 2023: 30 · 2022: 42 · 2021: 33 · 2020: 55 · 2019: 39 · 2018: 56 · 2017: 51 · 2016: 56 · 2015: 65 · 2014: 62 · 2013: 51 · 2012: 68
- FWCI
- 3.22
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Clinical Oncology (publishedVersion)
- PubMed (publishedVersion)
- Digital Commons - University of South Florida (University of South Florida) (submittedVersion)
- Funders
- National Institute on Aging (K23AG026749)
- Topics
- Health Sciences › Medicine › Geriatrics and Gerontology › Frailty in Older Adults
- Health Sciences › Medicine › Physiology › Nutrition and Health in Aging
- Health Sciences › Medicine › Geriatrics and Gerontology › Pharmaceutical Practices and Patient Outcomes
- Keywords
- comprehensive geriatric assessment, elderly cancer patients, functional status, comorbidities, cognitive function, nutritional status, psychological state, social support, medication review, quality of cancer care, geriatric oncology
- MeSH terms
- Aged, Cognition, Humans, Medical Oncology, Neoplasms, Nutritional Status, Social Support, Geriatric Assessment, Comorbidity, Polypharmacy, Disease Management
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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