Flexible Imputation of Missing Data
Abstract
Missing data form a problem in every scientific discipline, yet the techniques required to handle them are complicated and often lacking. One of the great ideas in statistical science-multiple imputation-fills gaps in the data with plausible values, the uncertainty of which is coded in the data itself. It also solves other problems, many of which a
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Missing item responses in completed questionnaires were filled in with multiple imputation using chained equations.
“Item-level missing data in the completed surveys were imputed using the method of multiple imputation (MI) by chained equations (van Buuren, 2012).”
From WHO World Mental Health Surveys International College Student Project: Prevalence and distribution of mental disorders. (2018) · cites this paper as van Buuren, 2012
Missing data were imputed using predictive mean matching and expectation maximization-two well-established imputation methods-and sensitivity analyses based on both imputation techniques led to very similar results.
“However, we imputed missing data using predictive mean matching and expectation maximization—two well-established imputation methods [42]-and sensitivity analyses based on both imputation techniques led to very similar results.”
All acquired data will be examined for inconsistencies and missing values, which will be replaced using multiple imputation methods if appropriate; a drop-out analysis will be performed; internal consistencies of newly translated inventories will be calculated; analyses will be intention-to-treat or completer-analyses; data-analysts will be blinded for group allocation.
“All acquired data will be examined with respect to potential inconsistencies and missing values, which will be replaced using multiple imputation methods [42], if appropriate. To detect potential systematic biases, a drop-out analysis will be performed.”
From HELP@APP: Development and evaluation of a self-help app for traumatized Syrian refugees in Germany- A study protocol of a randomized controlled trial (2019) · cites this paper as [42]
Multiple imputation by chained equations was used to adjust for within-survey item non-response, random internal subsampling of survey sections, and missing data due to skip logic errors.
“In addition, multiple imputation (MI) by chained equations(Van Buuren, 2012) was used to adjust for within-survey item non-response, random internal subsampling of survey sections, and missing data due to skip logic errors that occurred in a few surveys.”
From Severe role impairment associated with mental disorders: Results of the WHO World Mental Health Surveys International College Student Project (2018) · cites this paper as Van Buuren, 2012
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“Multiple imputation (MI) by chained equations (Buuren, 2012) was used to adjust for item-missing data, random internal sampling of survey sections in some countries to reduce survey length, and missing data due to skip logic errors that occurred Frontiers in Psychology | www.frontiersin.org 3 July…”
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“For the results of Multiple imputation, λ̄, the average proportion of variation in Q attributable to missing data is shown as well (Van Buuren, 2012, p. 41).”
MethodStatistical primer: how to deal with missing data in scientific research?†
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- Authors
- van Buuren, S.
- Venue
- Chapman & Hall/CRC eBooks
- Publisher
- Chapman and Hall/CRC
- Published
- 2012-03-29
- OpenAlex
- W612972800
- Cited by
- 2,022
- References
- 0
- Citations by year
- 2026: 81 · 2025: 69 · 2024: 69 · 2023: 119 · 2022: 111 · 2021: 268 · 2020: 296 · 2019: 222 · 2018: 204 · 2017: 164 · 2016: 140 · 2015: 144 · 2014: 81 · 2013: 44 · 2012: 9
- FWCI
- 22.42
- Type
- book
- Language
- en
- Open access
- closed
- Locations
- Chapman & Hall/CRC eBooks (publishedVersion)
- CERN Document Server (European Organization for Nuclear Research) (submittedVersion)
- Topics
- Physical Sciences › Mathematics › Statistics and Probability › Statistical Methods and Bayesian Inference
- Physical Sciences › Mathematics › Statistics and Probability › Markov Chains and Monte Carlo Methods
- Physical Sciences › Computer Science › Artificial Intelligence › Data Analysis with R
- Keywords
- missing data, multiple imputation, uncertainty quantification, missing data imputation
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