Differential expression of peroxisome proliferator-activated receptors (PPARs): tissue distribution of PPAR-alpha, -beta, and -gamma in the adult rat

Recent insights into the molecular pathophysiology of lipid droplet formation in hepatocytes

Sahini, N., & Borlak, J. T. (2014) · Progress in Lipid Research · doi:10.1016/j.plipres.2014.02.002 · Cited by 117

Role of peroxisome-proliferator-activated receptor β/δ (PPARβ/δ) in gastrointestinal tract function and disease

Peters, J. M., Hollingshead, H. E., & Gonzalez, F. J. (2008) · Clinical Science · doi:10.1042/cs20080022 · Cited by 117

Functional analysis of peroxisome-proliferator-responsive element motifs in genes of fatty acid-binding proteins

Schachtrup, C., Emmler, T., Bleck, B., Sandqvist, A., & Spener, F. (2004) · Biochemical Journal · doi:10.1042/bj20031340 · Cited by 115

Nuclear Receptors as New Perspective for the Management of Liver Diseases

Trauner, M., & Halilbasic, E. (2011) · Gastroenterology · doi:10.1053/j.gastro.2011.02.044 · Cited by 115

Myelin lipid metabolism and its role in myelination and myelin maintenance

Barnes-Vélez, J. A., Aksoy Yasar, F. B., & Hu, J. (2023) · The Innovation · doi:10.1016/j.xinn.2022.100360 · Cited by 73

Dietary Fish Oil Upregulates Intestinal Lipid Metabolism and Reduces Body Weight Gain in C57BL/6J Mice ,2

Mori, T., Kondo, H., Hase, T., Tokimitsu, I., & Murase, T. (2007) · Journal of Nutrition · doi:10.1093/jn/137.12.2629 · Cited by 114

Inhibition of NF-kappaB signaling by fenofibrate, a peroxisome proliferator-activated receptor-alpha ligand, presents a therapeutic strategy for rheumatoid arthritis.

Okamoto, H., Iwamoto, T., Kotake, S., Momohara, S., Yamanaka, H., & Kamatani, N. (2005) · PubMed · Cited by 113

Molecular cloning and expression pattern of 11 genes involved in lipid metabolism in yellow catfish Pelteobagrus fulvidraco

Zheng, J., Luo, Z., Zhu, Q., Tan, X.-Y., Chen, Q., Sun, L., & Hu, W. (2013) · Gene · doi:10.1016/j.gene.2013.08.028 · Cited by 112

PPARα gene variation and physical performance in Russian athletes

Ahmetov, I. I., Mozhayskaya, I. A., Flavell, D. M., Astratenkova, I. V., Komkova, A. I., Lyubaeva, E. V., Tarakin, P. P., Shenkman, B. S., Vdovina, A. B., Netreba, A. I., et al. (2006) · European Journal of Applied Physiology · doi:10.1007/s00421-006-0154-4 · Cited by 112

Identification of a novel gene, OASIS, which encodes for a putative CREB/ATF family transcription factor in the long-term cultured astrocytes and gliotic tissue

Honma, Y., Kanazawa, K., Mori, T., Tanno, Y., Tojo, M., Kiyosawa, H., Takeda, J., Nikaido, T., Tsukamoto, T., Yokoya, S., et al. (1999) · Molecular Brain Research · doi:10.1016/s0169-328x(99)00102-3 · Cited by 112

Ginsenoside 20(S)-Protopanaxatriol (PPT) Activates Peroxisome Proliferator-Activated Receptor γ (PPARγ) in 3T3-L1 Adipocytes

Han, K. L., Jung, M. H., Sohn, J. H., & Hwang, J. (2006) · Biological and Pharmaceutical Bulletin · doi:10.1248/bpb.29.110 · Cited by 111

Localization of PPARδ in murine central nervous system: expression in oligodendrocytes and neurons

Woods, J. W., Tanen, M., Figueroa, D. J., Biswas, C., Zycband, E., Moller, D. E., Austin, C. P., & Berger, J. P. (2003) · Brain Research · doi:10.1016/s0006-8993(03)02515-0 · Cited by 113

Peroxisome proliferator-activated receptors and cardiovascular remodeling

Schiffrin, E. L. (2004) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00677.2004 · Cited by 110

Identification of Novel Peroxisome Proliferator-Activated Receptor α (PPARα) Target Genes in Mouse Liver Using cDNA Microarray Analysis

Cherkaoui‐Malki, M., Meyer, K., Wq, C., Latruffe, N., Yeldandi, A. V., Rao, M. S. R., Bradfield, C. A., & Reddy, J. K. (2001) · Gene Expression · doi:10.3727/000000001783992533 · Cited by 113

From chronic overnutrition to metaflammation and insulin resistance: adipose tissue and liver contributions

Caputo, T., Gilardi, F., & Desvergne, B. (2017) · FEBS Letters · doi:10.1002/1873-3468.12742 · Cited by 112

PPARβ/δ: linking metabolism to regeneration

Magadum, A., & Engel, F. B. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19072013 · Cited by 110

Peroxisome Proliferator-Activated Receptors (PPARs): from metabolic control to epidermal wound healing

Wahli, W. (2002) · Swiss Medical Weekly · doi:10.4414/smw.2002.09939 · Cited by 110

Regulation of Triglyceride Metabolism by PPARs : Fibrates and Thiazolidinediones have Distinct Effects

Auwerx, J. H., Schoonjans, K., Fruchart, J., & Staels, B. (1996) · Journal of Atherosclerosis and Thrombosis · doi:10.5551/jat1994.3.81 · Cited by 111

Activation of peroxisome proliferator-activated receptor isoforms and inhibition of prostaglandin H2 synthases by ibuprofen, naproxen, and indomethacin11Abbreviations: AA, arachidonic acid; ACO, acyl-CoA oxidase; COX; cyclooxygenase; NSAIDs, nonsteroidal anti-inflammatory drugs; PGHS, prostaglandin endoperoxide H synthase; PPP, platelet-poor plasma; PRP, platelet-rich plasma; PPAR, peroxisome proliferator-activated receptor; PPRE, peroxisome proliferator response element; and CoA coenzyme A.

Jaradat, M., Wongsud, B., Phornchirasilp, S., Rangwala, S. M., Shams, G. E.-D. A. M., Sutton, M., Romstedt, K. J., Noonan, D. J., & Feller, D. R. (2001) · Biochemical Pharmacology · doi:10.1016/s0006-2952(01)00822-x · Cited by 109

Peroxisome Proliferator–induced Pleiotropic Responses: Pursuit of a Phenomenona

Reddy, J. K., & Chu, R. (1996) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1996.tb18616.x · Cited by 110

PPARγ in Placental Angiogenesis

Nadra, K., Quignodon, L., Sardella, C., Joye, E., Mucciolo, A., Chrast, R., & Desvergne, B. (2010) · Endocrinology · doi:10.1210/en.2010-0131 · Cited by 109

Regulation of inflammation by PPARs: a future approach to treat lung inflammatory diseases?

Becker, J., Delayre‐Orthez, C., Frossard, N., & Pons, F. (2006) · Fundamental and Clinical Pharmacology · doi:10.1111/j.1472-8206.2006.00425.x · Cited by 109

PPAR Agonists Protect Mesangial Cells from Interleukin 1β-Induced Intracellular Lipid Accumulation by Activating the ABCA1 Cholesterol Efflux Pathway

Ruan, X. Z., Moorhead, J. F., Fernando, R. L., Wheeler, D. C., Powis, S. H., & Varghese, Z. (2003) · Journal of the American Society of Nephrology · doi:10.1097/01.asn.0000050414.52908.da · Cited by 109

Potentiation of Insulin Signaling in Tissues of Zucker Obese Rats After Acute and Long-Term Treatment With PPARγ Agonists

Jiang, G., Dallas-Yang, Q., Li, Z., Szalkowski, D., Liu, F., Shen, X., Wu, M. S., Zhou, G., Doebber, T. W., Berger, J., et al. (2002) · Diabetes · doi:10.2337/diabetes.51.8.2412 · Cited by 106

Physiological and Therapeutic Roles of Peroxisome Proliferator-Activated Receptors

Berger, J. P., & Wagner, J. A. (2002) · Diabetes Technology & Therapeutics · doi:10.1089/15209150260007381 · Cited by 107

RXR: From Partnership to Leadership in Metabolic Regulations

Desvergne, B. (2007) · Vitamins and hormones · doi:10.1016/s0083-6729(06)75001-4 · Cited by 109

PPARβ/δ Regulates Paneth Cell Differentiation Via Controlling the Hedgehog Signaling Pathway

Varnat, F., ten Heggeler-Bordier, B., Grisel, P., Boucard, N., Corthesy-Theulaz, I. E., Wahli, W., & Desvergne, B. (2006) · Gastroenterology · doi:10.1053/j.gastro.2006.05.004 · Cited by 109

Inhibition of the transcription factors AP-1 and NF-κB in CD4 T cells by peroxisome proliferator-activated receptor γ ligands

Wang, P., Anderson, P. O., Chen, S., Paulsson, K. M., Sjögren, H. O., & Li, S. (2001) · International Immunopharmacology · doi:10.1016/s1567-5769(01)00015-7 · Cited by 108

Pioglitazone Inhibits Cell Growth and Reduces Matrix Production in Human Kidney Fibroblasts

Zafiriou, S., Stanners, S. R., Saad, S., Polhill, T. S., Poronnik, P., & Pollock, C. A. (2005) · Journal of the American Society of Nephrology · doi:10.1681/asn.2004040278 · Cited by 107

Roles of PPARs on regulating myocardial energy and lipid homeostasis

Yang, Q., & Li, Y. (2007) · Journal of Molecular Medicine · doi:10.1007/s00109-007-0170-9 · Cited by 106

Alcoholic Liver Injury in the Rat Is Associated with Reduced Expression of Peroxisome Proliferator-α (PPARα)-Regulated Genes and Is Ameliorated by PPARα Activation

Nanji, A. A., Dannenberg, A. J., Jokelainen, K., & Bass, N. M. (2004) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.103.064717 · Cited by 107

Association of Bone Mineral Density with a Polymorphism of the Peroxisome Proliferator-Activated Receptor γ Gene: PPARγ Expression in Osteoblasts

Ogawa, S., Urano, T., Hosoi, T., Miyao, M., Hoshino, S., Fujita, M., Shiraki, M., Orimo, H., Ouchi, Y., & Inoue, S. (1999) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1999.0896 · Cited by 102

Toxicological consequences of altered peroxisome proliferator-activated receptor γ (PPARγ) expression in the liver: insights from models of obesity and type 2 diabetes11Abbreviations: PPAR, peroxisome proliferator-activated receptor; 15d-PGJ2, 15-deoxy-Δ12,14-prostaglandin J2; NEFA, non-esterified fatty acid; T2DM, type 2 (non-insulin-dependent) diabetes mellitus; LPS, lipopolysaccharide; NSAIDs, nonsteroidal anti-inflammatory drugs; IL, interleukin; TNF α, tumor necrosis factor-α; TRAIL, tumor necrosis factor-related apoptosis-inducing ligand; and TZD, thiazolidinedione.

Boelsterli, U. A., & Bedoucha, M. (2002) · Biochemical Pharmacology · doi:10.1016/s0006-2952(01)00817-6 · Cited by 103

Caloric restriction of db/db mice reverts hepatic steatosis and body weight with divergent hepatic metabolism

Kim, K. E., Jung, Y., Min, S., Nam, M., Heo, R. W., Jeon, B. T., Song, D. H., Yi, C., Jeong, E. A., Kim, H., et al. (2016) · Scientific Reports · doi:10.1038/srep30111 · Cited by 112

PPAR? in endothelial cells influences high fat diet-induced hypertension

Nicol, C. J. B., ADACHI, M., AKIYAMA, T., & Gonzalez, F. J. (2005) · American Journal of Hypertension · doi:10.1016/j.amjhyper.2004.10.032 · Cited by 105

Expression of PPAR and RXR Isoforms in the Developing Rat and Human Term Placentas

Wang, Q., Fujii, H., & Knipp, G. T. (2002) · Placenta · doi:10.1053/plac.2002.0855 · Cited by 108

Activation of Peroxisome Proliferator-Activated Receptor-γ and Retinoid X Receptor Inhibits Aromatase Transcription via Nuclear Factor-κB

Fan, W., Yanase, T., Morinaga, H., Mu, Y.-M., Nomura, M., Okabe, T., Goto, K., Harada, N., & Nawata, H. (2004) · Endocrinology · doi:10.1210/en.2004-1046 · Cited by 107

Ovotoxicity and PPAR-mediated aromatase downregulation in female Sprague–Dawley rats following combined oral exposure to benzo[a]pyrene and di-(2-ethylhexyl) phthalate

Xu, C. S., Chen, J., Qiu, Z., Zhao, Q., Luo, J., Yang, L., Zeng, H., Huang, Y., Zhang, L., Cao, J., et al. (2010) · Toxicology Letters · doi:10.1016/j.toxlet.2010.09.015 · Cited by 104

Role of PPAR, LXR, and PXR in epidermal homeostasis and inflammation

Schmuth, M., Moosbrugger-Martinz, V., Blunder, S., & Dubrac, S. (2014) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2013.11.012 · Cited by 100

Transcriptional Regulation of Metabolic Pathways via Lipid-Sensing Nuclear Receptors PPARs, FXR, and LXR in NASH

Cariello, M., Piccinin, E., & Moschetta, A. (2021) · Cellular and Molecular Gastroenterology and Hepatology · doi:10.1016/j.jcmgh.2021.01.012 · Cited by 108

Fetal Epidermal Differentiation and Barrier Development In Vivo is Accelerated by Nuclear Hormone Receptor Activators1

Hanley, K., Kömüves, L. G., Bass, N. M., He, S., Jiang, Y. J., Crumrine, D. A., Appel, R., Friedman, M., Bettencourt, J. A., Min, K., et al. (1999) · Journal of Investigative Dermatology · doi:10.1046/j.1523-1747.1999.00743.x · Cited by 103

Keratinocyte Differentiation in Hyperproliferative Epidermis: Topical Application of PPARα Activators Restores Tissue Homeostasis

Kömüves, L. G., Hanley, K., Man, M., Elias, P. M., Williams, M. L. K., & Feingold, K. R. (2000) · Journal of Investigative Dermatology · doi:10.1046/j.1523-1747.2000.00076.x · Cited by 103

Glucose-Induced Preproinsulin Gene Expression Is Inhibited by the Free Fatty Acid Palmitate

Ritz-Laser, B., Meda, P., Constant, I., Klages, N., Charollais, A., Morales, A., Magnan, C., Ktorza, A., & Philippé, J. (1999) · Endocrinology · doi:10.1210/endo.140.9.6953 · Cited by 114

Elevated Production of Docosahexaenoic Acid in Females: Potential Molecular Mechanisms

Kitson, A. P., Stroud, C. K., & Stark, K. D. (2010) · Lipids · doi:10.1007/s11745-010-3391-6 · Cited by 106

Association between the PPARα-L162V polymorphism and components of the metabolic syndrome

Robitaille, J., Brouillette, C., Houde, A., Lemieux, S., Përusse, L., Tchernof, A., Gaudet, D., & Vohl, M. (2004) · Journal of Human Genetics · doi:10.1007/s10038-004-0177-9 · Cited by 103

Pioglitazone and Sodium Salicylate Protect Human β-Cells against Apoptosis and Impaired Function Induced by Glucose and Interleukin-1β

Zeender, E., Maedler, K., Bosco, D., Berney, T., Donath, M. Y., & Halban, P. A. (2004) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2004-0446 · Cited by 103

Troglitazone Effects on Gene Expression in Human Skeletal Muscle of Type II Diabetes Involve Up-Regulation of Peroxisome Proliferator-Activated Receptor-γ1

Park, K. S., Ciaraldi, T. P., Lindgren, K., Abrams-Carter, L., Mudaliar, S. R. D., Nikoulina, S. E., Tufari, S. R., Veerkamp, J. H., Vidal‐Puig, A., & Henry, R. R. (1998) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.83.8.5034 · Cited by 103

Expression of peroxisome proliferator-activated receptors (PPARS) in human astrocytic cells: PPAR? agonists as inducers of apoptosis

Chattopadhyay, N., Singh, D. P., Heese, O., Godbole, M. M., Shinohara, T., Black, P. M., & Brown, E. M. (2000) · Journal of Neuroscience Research · doi:10.1002/1097-4547(20000701)61:1 · Cited by 103

Differential Expression of the Peroxisome Proliferator-Activated Receptor γ (PPARγ) and Its Coactivators Steroid Receptor Coactivator-1 and PPAR-Binding Protein PBP in the Brown Fat, Urinary Bladder, Colon, and Breast of the Mouse

Jain, S. R., Pulikuri, S., Zhu, Y., Qi, C., Kanwar, Y. S., Yeldandi, A. V., Rao, M. S., & Reddy, J. K. (1998) · American Journal Of Pathology · doi:10.1016/s0002-9440(10)65577-0 · Cited by 101

Regulation of insulin secretion, glucokinase gene transcription and beta cell proliferation by adipocyte-derived Wnt signalling molecules

Schinner, S., Ülgen, F., Papewalis, C., Schott, M., Woelk, A., Vidal‐Puig, A., & Scherbaum, W. A. (2007) · Diabetologia · doi:10.1007/s00125-007-0848-0 · Cited by 102

Inhibition of phosphoenolpyruvate carboxykinase (PEPCK) gene expression by troglitazone: a peroxisome proliferator-activated receptor-γ (PPARγ)-independent, antioxidant-related mechanism11Abbreviations: BADGE, bisphenol A diglycidyl ether; DCF, dichlorofluorescein; DCFH, 5- (and 6-)carboxy-2′,7′-dichlorodihydrofluorescein; PEPCK, phosphoenolpyruvate carboxykinase; 15-PGJ2, 15-deoxy-Δ12,14-prostaglandin J2; PPAR, peroxisome proliferator-activated receptor; RPPO, ribosomal phosphoprotein PO; TZD, thiazolidinedione.

Davies, G. F., Khandelwal, R. L., Wu, L., Juurlink, B. H. J., & Roesler, W. J. (2001) · Biochemical Pharmacology · doi:10.1016/s0006-2952(01)00764-x · Cited by 102

PPARα activation increases triglyceride mass and adipose differentiation-related protein in hepatocytes

Edvardsson, U., Ljungberg, A., Lindén, D., William‐Olsson, L., Peilot, H., Ahnmark, A., & Oscarsson, J. (2005) · Journal of Lipid Research · doi:10.1194/jlr.m500203-jlr200 · Cited by 101

Pioglitazone preserves pancreatic islet structure and insulin secretory function in three murine models of type 2 diabetes

Diani, A. R., Sawada, G., Wyse, B., Murray, F. T., & Khan, M. (2004) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00331.2003 · Cited by 100

Expression of peroxisome proliferator‐activated receptors (PPARs) in human urinary bladder carcinoma and growth inhibition by its agonists

Yoshimura, R., Matsuyama, M., Segawa, Y., Hase, T., Mitsuhashi, M., Tsuchida, K., Wada, S., Kawahito, Y., Sano, H., & Nakatani, T. (2003) · International Journal of Cancer · doi:10.1002/ijc.10980 · Cited by 104

Trigonelline and diosgenin attenuate ER stress, oxidative stress-mediated damage in pancreas and enhance adipose tissue PPARγ activity in type 2 diabetic rats

Tharaheswari, M., Reddy, N. J., Kumar, R., Varshney, K. C., Kannan, M., & Sadras, S. R. (2014) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-014-2152-x · Cited by 101

Mechanisms by Which Dietary Fatty Acids Regulate Mitochondrial Structure-Function in Health and Disease

Sullivan, E. M., Pennington, E. R., Green, W. D., Beck, M. A., Brown, D. A., & Shaikh, S. R. (2018) · Advances in Nutrition · doi:10.1093/advances/nmy007 · Cited by 105

Peroxisome Proliferator-Activated Receptor δ and γ Agonists Differentially Alter Tumor Differentiation and Progression during Mammary Carcinogenesis

Yin, Y., Russell, R. G., Dettin, L. E., Bai, R., Wei, Z.-L., Kozikowski, A. P., Kopleovich, L., & Glazer, R. I. (2005) · Cancer Research · doi:10.1158/0008-5472.can-04-3990 · Cited by 101

Glia and immune cell signaling in bipolar disorder: insights from neuropharmacology and molecular imaging to clinical application

Watkins, C. C., Sawa, A., & Pomper, M. G. (2014) · Translational Psychiatry · doi:10.1038/tp.2013.119 · Cited by 100

PPARs and Microbiota in Skeletal Muscle Health and Wasting

Manickam, R., Duszka, K., & Wahli, W. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21218056 · Cited by 104

Uncoupling proteins in the mitochondrial defense against oxidative stress

Hass, D. T., & Barnstable, C. J. (2021) · Progress in Retinal and Eye Research · doi:10.1016/j.preteyeres.2021.100941 · Cited by 104

PPAR-α effects on the heart and other vascular tissues

Francis, G. A., Annicotte, J., & Auwerx, J. H. (2003) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.01118.2002 · Cited by 100

Nuclear Receptors as Drug Targets in Cholestatic Liver Diseases

Halilbasic, E., Baghdasaryan, A., & Trauner, M. (2013) · Clinics in Liver Disease · doi:10.1016/j.cld.2012.12.001 · Cited by 100

Activation of Mitogen-Activated Protein Kinases by Peroxisome Proliferator-Activated Receptor Ligands: An Example of Nongenomic Signaling

Gardner, O., Dewar, B. J., & Graves, L. M. (2005) · Molecular Pharmacology · doi:10.1124/mol.105.012260 · Cited by 99

Nuclear receptors linking metabolism, inflammation, and fibrosis in nonalcoholic fatty liver disease

Puengel, T., Liu, H., Guillot, A., Heymann, F., Tacke, F., & Peiseler, M. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23052668 · Cited by 95

A mitochondrial ketogenic enzyme regulates its gene expression by association with the nuclear hormone receptor PPARα

Meertens, L. M., Miyata, K., Cechetto, J. D., Rachubinski, R. A., & Capone, J. P. (1998) · The EMBO Journal · doi:10.1093/emboj/17.23.6972 · Cited by 99

Premature fat deposition in the salivary glands associated with Sjögren syndrome: MR and CT evidence.

Izumi, M., Eguchi, K., Nakamura, H., Nagataki, S., & Nakamura, T. (1997) · PubMed Central · Cited by 98

Expression of porcine adipocyte transcripts: tissue distribution and differentiation in vitro and in vivo

Ding, S., McNeel, R. L., & Mersmann, H. J. (1999) · Comparative Biochemistry and Physiology Part B Biochemistry and Molecular Biology · doi:10.1016/s0305-0491(99)00077-2 · Cited by 98

TNF‐α downregulates the peroxisome proliferator activated receptor‐α and the mRNAs encoding peroxisomal proteins in rat liver

Beier, K., Völkl, A., & Fahimi, H. D. (1997) · FEBS Letters · doi:10.1016/s0014-5793(97)00805-3 · Cited by 98

Ligand Activation of Peroxisome Proliferator–Activated Receptor β/δ (PPARβ/δ) Attenuates Carbon Tetrachloride Hepatotoxicity by Downregulating Proinflammatory Gene Expression

Shan, W., Palkar, P. S., Murray, I. A., McDevitt, E. I., Kennett, M. J., Kang, B. H., Isom, H. C., Perdew, G. H., Gonzalez, F. J., & Peters, J. M. (2008) · Toxicological Sciences · doi:10.1093/toxsci/kfn142 · Cited by 97

Mechanisms of hepatic fatty acid oxidation and ketogenesis during fasting

Ruppert, P. M. M., & Kersten, S. (2023) · Trends in Endocrinology and Metabolism · doi:10.1016/j.tem.2023.10.002 · Cited by 103

Expression of peroxisome proliferator-activated receptors in zebrafish (Danio rerio)

Ibabe, A., Grabenbauer, M., Baumgart‐Vogt, E., Fahimi, D. H., & Cajaraville, M. P. (2002) · Histochemistry and Cell Biology · doi:10.1007/s00418-002-0434-y · Cited by 98

Deletion of the Aryl Hydrocarbon Receptor-associated Protein 9 Leads to Cardiac Malformation and Embryonic Lethality

Lin, B. C., Sullivan, R., Lee, Y., Moran, S. M., Glover, E. A., & Bradfield, C. A. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m705471200 · Cited by 97

15-deoxy-Δ12,14-PGJ2: endogenous PPARγ ligand or minor eicosanoid degradation product?

Powell, W. S. (2003) · Journal of Clinical Investigation · doi:10.1172/jci19796 · Cited by 97

The Peroxisome Proliferator-Activated Receptor N-Terminal Domain Controls Isotype-Selective Gene Expression and Adipogenesis

Hummasti, S., & Tontonoz, P. (2006) · Molecular Endocrinology · doi:10.1210/me.2006-0025 · Cited by 100

Exposure to the Immunosuppresant, Perfluorooctanoic Acid, Enhances the Murine IgE and Airway Hyperreactivity Response to Ovalbumin

Fairley, K. J., Purdy, R., Kearns, S., Anderson, S. E., & Meade, B. J. (2007) · Toxicological Sciences · doi:10.1093/toxsci/kfm053 · Cited by 100

Expression and Functional Role of Peroxisome Proliferator-Activated Receptor-γ in Ovarian Folliculogenesis in the Sheep1

Froment, P., Fabre, S., Dupont, J., Pisselet, C., Chesneau, D., Staels, B., & Monget, P. (2003) · Biology of Reproduction · doi:10.1095/biolreprod.103.017244 · Cited by 96

15-Deoxy-Δ12,14-prostaglandin J2, a specific ligand for peroxisome proliferator-activated receptor-γ, induces neuronal apoptosis

Rohn, T. T., Wong, S. M., Cotman, C. W., & Cribbs, D. H. (2001) · Neuroreport · doi:10.1097/00001756-200103260-00043 · Cited by 95

WY14,643, a PPARα Ligand, Has Profound Effects on Immune Responses In Vivo

Cunard, R. A., DiCampli, D., Archer, D. C., Stevenson, J. L., Ricote, M., Glass, C. K., & Kelly, C. (2002) · The Journal of Immunology · doi:10.4049/jimmunol.169.12.6806 · Cited by 96

Nuclear receptors in neurodegenerative diseases

Skerrett, R., Malm, T., & Landreth, G. (2014) · Neurobiology of Disease · doi:10.1016/j.nbd.2014.05.019 · Cited by 94

Pharmacogenetics of Anti-Diabetes Drugs

DiStefano, J. K., & Watanabe, R. M. (2010) · Pharmaceuticals · doi:10.3390/ph3082610 · Cited by 96

Liver macrophages and inflammation in physiology and physiopathology of non‐alcoholic fatty liver disease

Thibaut, R., Gage, M., Pineda‐Torra, I., Chabrier, G., Venteclef, N., & Alzaïd, F. (2021) · FEBS Journal · doi:10.1111/febs.15877 · Cited by 97

Characterisation of Bovine Peroxisome Proliferator-Activated Receptors γ1 and γ2: Genetic Mapping and Differential Expression of the Two Isoforms

Sundvold, H., Brzozowska, A., & Lien, S. (1997) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1997.7564 · Cited by 98

Treatment of type 2 diabetic db/db mice with a novel PPARγ agonist improves cardiac metabolism but not contractile function

Carley, A. N., Semeniuk, L. M., Shimoni, Y., Aasum, E., Larsen, T. S., Berger, J. P., & Severson, D. L. (2004) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00329.2003 · Cited by 94

Clinically relevant concentrations of di (2-ethylhexyl) phthalate (DEHP) uncouple cardiac syncytium

Posnack, N. G., Karabekian, Z. I., Swift, L., Brown, R. P., Kay, M. W., & Sarvazyan, N. A. (2009) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2008.12.027 · Cited by 94

Recent update on the PPARα-null mouse

Gonzalez, F. J. (1997) · Biochimie · doi:10.1016/s0300-9084(97)81506-4 · Cited by 95

PPAR and Immune System-What Do We Know?

Zhang, X., & Young, H. A. (2002) · International Immunopharmacology · doi:10.1016/s1567-5769(02)00057-7 · Cited by 123

Fatty acid metabolism in fish species as a biomarker for environmental monitoring

Olivares‐Rubio, H. F., & Vega‐López, A. (2016) · Environmental Pollution · doi:10.1016/j.envpol.2016.07.005 · Cited by 99

Peroxisome proliferator-activated receptor-β/δ protects against chemically induced liver toxicity in mice

Shan, W., Nicol, C. J. B., Ito, S., Bility, M. T., Kennett, M. J., Ward, J. M., Gonzalez, F. J., & Peters, J. M. (2007) · Hepatology · doi:10.1002/hep.21925 · Cited by 94

Positioning prostanoids of the D and J series in the immunopathogenic scheme

Herlong, J. L., & Scott, T. R. (2005) · Immunology Letters · doi:10.1016/j.imlet.2005.10.004 · Cited by 94

Long-Term Treatment With Rosiglitazone and Metformin Reduces the Extent of, but Does Not Prevent, Islet Amyloid Deposition in Mice Expressing the Gene for Human Islet Amyloid Polypeptide

Hull, R. L., Shen, Z.-P., Watts, M. R., Kodama, K., Carr, D. B., Utzschneider, K. M., Zraika, S., Wang, F., & Kahn, S. E. (2005) · Diabetes · doi:10.2337/diabetes.54.7.2235 · Cited by 93

Phenolics with PPAR-γ ligand-Binding activity obtained from licorice ( Glycyrrhiza uralensis Roots) and ameliorative effects of glycyrin on genetically diabetic KK-A y mice

Kuroda, M., Mimaki, Y., Sashida, Y., Mae, T., Kishida, H., Nishiyama, T., Tsukagawa, M., Konishi, E., Takahashi, K., Kawada, T., et al. (2003) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/j.bmcl.2003.09.052 · Cited by 93

Atorvastatin Ester Regulates Lipid Metabolism in Hyperlipidemia Rats via the PPAR-signaling Pathway and HMGCR Expression in the Liver

Hu, N., Chen, C., Wang, J., Huang, J. M., Yao, D., & Li, C. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms222011107 · Cited by 93

The effects of branched-chain amino acid granules on the accumulation of tissue triglycerides and uncoupling proteins in diet-induced obese mice

Arakawa, M., Masaki, T., Nishimura, J., Seike, M., & Yoshimatsu, H. (2011) · Endocrine Journal · doi:10.1507/endocrj.k10e-221 · Cited by 97

Peroxisome Proliferator-activated Receptor β (δ)-dependent Regulation of Ubiquitin C Expression Contributes to Attenuation of Skin Carcinogenesis

Kim, D. J., Akiyama, T. E., Harman, F. S., Burns, A., Shan, W., Ward, J. M., Kennett, M. J., Gonzalez, F. J., & Peters, J. M. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m312063200 · Cited by 92

Fenofibrate prevents Rosiglitazone-induced body weight gain in ob/ob mice

Carmona, M. C., Louche, K., Nibbelink, M. M., Prunet‐Marcassus, B., Bross, A., Desbazeille, M., Dacquet, C., Renard, P., Casteilla, L., & Pénicaud, L. (2005) · International Journal of Obesity · doi:10.1038/sj.ijo.0802943 · Cited by 89

Pioglitazone Reduces Islet Triglyceride Content and Restores Impaired Glucose-Stimulated Insulin Secretion in Heterozygous Peroxisome Proliferator–Activated Receptor-γ–Deficient Mice on a High-Fat Diet

Matsui, J., Terauchi, Y., Kubota, N., Takamoto, I., Eto, K., Yamashita, T., Komeda, K., Yamauchi, T., Kamon, J., Kita, S., et al. (2004) · Diabetes · doi:10.2337/diabetes.53.11.2844 · Cited by 93

Roles of Peroxisome Proliferator-Activated Receptor β/δ in skeletal muscle physiology

Manickam, R., & Wahli, W. (2016) · Biochimie · doi:10.1016/j.biochi.2016.11.010 · Cited by 98

Antidiabetic thiazolidinediones inhibit invasiveness of pancreatic cancer cells via PPARγ independent mechanisms

Galli, A., Ceni, E., Crabb, D. W., Mello, T., Salzano, R., Grappone, C., Milani, S., Surrenti, E., Surrenti, C., & Casini, A. (2004) · Gut · doi:10.1136/gut.2003.031997 · Cited by 91

Inhibition of 12/15-lipoxygenase by baicalein induces microglia PPARβ/δ: a potential therapeutic role for CNS autoimmune disease

Xu, J., Zhang, Y., Xiao, Y., Ma, S., Liu, Q., Dang, S., Jin, M., Shi, Y., Wan, B., & Zhang, Y. (2013) · Cell Death and Disease · doi:10.1038/cddis.2013.86 · Cited by 91

Peroxisome Proliferator Activated Receptor

(2006) · Springer eBooks · doi:10.1007/3-540-29719-0_1236

Printed in U.S.A. Copyright © 1998 by The Endocrine Society Differential Expression of Peroxisome Proliferator- Activated Receptor-�,-�, and- � during Rat

Development, E., Braissant, O., & Wahli, W. (2013)

Differential Expression of Peroxisome Proliferator-Activated Receptor- , - , and - during Rat Embryonic Development

Braissant, O., & Wahli, W. (1998) · Endocrinology · doi:10.1210/endo.139.6.6049 · Cited by 457

Prostaglandin and PPAR control of immune cell function

Rotondo, D., & Davidson, J. (2002) · Immunology · doi:10.1046/j.0019-2805.2001.01361.x · Cited by 20

The peroxisome proliferator activated receptors (PPARs) and their effects on lipid metabolism and adipocyte differentiation

Schoonjans, K., Staels, B., & Auwerx, J. H. (1996) · Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism · doi:10.1016/0005-2760(96)00066-5 · Cited by 1,045