Nuclear receptors in neurodegenerative diseases

Alternative activation of macrophages: mechanism and functions

Gordon, S., & Martinez, F. O. (2010) · Immunity · doi:10.1016/j.immuni.2010.05.007 · Cited by 4,197 · see citing works

Differential expression of peroxisome proliferator-activated receptors (PPARs): tissue distribution of PPAR-alpha, -beta, and -gamma in the adult rat

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Fatty acids and eicosanoids regulate gene expression through direct interactions with peroxisome proliferator-activated receptors α and γ

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Macrophage-specific PPARγ controls alternative activation and improves insulin resistance

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Nuclear Receptors and Lipid Physiology: Opening the X-Files

Chawla, A., Repa, J. J., Evans, R. M., & Mangelsdorf, D. J. (2001) · Science · doi:10.1126/science.294.5548.1866 · Cited by 2,085 · see citing works

The role of apolipoprotein E in Alzheimer's disease

Kim, J., Basak, J. M., & Holtzman, D. M. (2009) · Neuron · doi:10.1016/j.neuron.2009.06.026 · Cited by 1,661 · see citing works

Microglia development and function

Nayak, D., Roth, T. L., & McGavern, D. B. (2014) · Annual Review of Immunology · doi:10.1146/annurev-immunol-032713-120240 · Cited by 1,154 · see citing works

ApoE-Directed Therapeutics Rapidly Clear β-Amyloid and Reverse Deficits in AD Mouse Models

Cramer, P. E., Cirrito, J. R., Wesson, D. W., Lee, C. Y. D., Karlo, J. C., Zinn, A. E., Casali, B. T., Restivo, J. L., Goebel, W. D., James, M. J., et al. (2012) · Science · doi:10.1126/science.1217697 · Cited by 1,050 · see citing works

CREB and the CRTC co-activators: sensors for hormonal and metabolic signals

Altarejos, J. Y., & Montminy, M. (2011) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm3072 · Cited by 1,035 · see citing works

Liver X receptors as integrators of metabolic and inflammatory signaling

Zelcer, N. (2006) · Journal of Clinical Investigation · doi:10.1172/jci27883 · Cited by 978 · see citing works

PARIS (ZNF746) Repression of PGC-1α Contributes to Neurodegeneration in Parkinson's Disease

Shin, J.-H., Ko, H. S., Kang, H., Lee, Y., Lee, Y.-I., Pletinkova, O., Troconso, J. C., Dawson, V. L., & Dawson, T. M. (2011) · Cell · doi:10.1016/j.cell.2011.02.010 · Cited by 953 · see citing works

ApoE Promotes the Proteolytic Degradation of Aβ

Jiang, Q., Lee, C. Y. D., Mandrekar, S., Wilkinson, B., Cramer, P., Zelcer, N., Mann, K., Lamb, B., Willson, T. M., Collins, J. L., et al. (2008) · Neuron · doi:10.1016/j.neuron.2008.04.010 · Cited by 876 · see citing works

Heterogeneity of Microglial Activation in the Innate Immune Response in the Brain

Colton, C. A. (2009) · Journal of Neuroimmune Pharmacology · doi:10.1007/s11481-009-9164-4 · Cited by 871 · see citing works

A Nurr1/CoREST Pathway in Microglia and Astrocytes Protects Dopaminergic Neurons from Inflammation-Induced Death

Saijo, K., Winner, B., Carson, C. T., Collier, J. G., Boyer, L., Rosenfeld, M. G., Gage, F. H., & Glass, C. K. (2009) · Cell · doi:10.1016/j.cell.2009.01.038 · Cited by 859 · see citing works

Docosahexaenoic Acid, a Ligand for the Retinoid X Receptor in Mouse Brain

de Urquiza, A. M., Liu, S., Sjöberg, M., Zetterström, R. H., Griffiths, W. J., Sjövall, J., & Perlmann, T. (2000) · Science · doi:10.1126/science.290.5499.2140 · Cited by 745 · see citing works

Apoptotic Cells Promote Their Own Clearance and Immune Tolerance through Activation of the Nuclear Receptor LXR

A-González, N., Bensinger, S. J., Hong, C., Beceiro, S., Bradley, M. N., Zelcer, N., Deniz, J. M., Ramírez, C. M., Díaz, M., Gallardo, G., et al. (2009) · Immunity · doi:10.1016/j.immuni.2009.06.018 · Cited by 674 · see citing works

Alternative macrophage activation and metabolism

Odegaard, J. I., & Chawla, A. (2011) · Annual Review of Pathology: Mechanisms of Disease · doi:10.1146/annurev-pathol-011110-130138 · Cited by 640 · see citing works

Growth, Adipose, Brain, and Skin Alterations Resulting from Targeted Disruption of the Mouse Peroxisome Proliferator-Activated Receptor β(δ)

Peters, J. M., Lee, S. S. T., Li, W., Ward, J. M., Gavrilova, O., Grueter, C. A., Reitman, M. L., Hudson, L. D., & Gonzalez, F. J. (2000) · Molecular and Cellular Biology · doi:10.1128/mcb.20.14.5119-5128.2000 · Cited by 631 · see citing works

Nuclear receptor transrepression pathways that regulate inflammation in macrophages and T cells

Glass, C. K., & Saijo, K. (2010) · Nature Reviews Immunology · doi:10.1038/nri2748 · Cited by 619 · see citing works

Microglial dysfunction in brain aging and Alzheimer's disease

Mosher, K. I., & Wyss-Coray, T. (2014) · Biochemical Pharmacology · doi:10.1016/j.bcp.2014.01.008 · Cited by 618 · see citing works

Immunolocalization of peroxisome proliferator-activated receptors and retinoid x receptors in the adult rat CNS

Moreno, S., Vecchioli, S. F., & Cerù, M. P. (2003) · Neuroscience · doi:10.1016/j.neuroscience.2003.08.064 · Cited by 581 · see citing works

Acute treatment with the PPARγ agonist pioglitazone and ibuprofen reduces glial inflammation and Aβ1–42 levels in APPV717I transgenic mice

Heneka, M. T., Sastre, M., Dumitrescu-Ozimek, L., Hanke, A., Dewachter, I., Kuiperi, C., O'Banion, K., Klockgether, T., Van Leuven, F., & Landreth, G. E. (2005) · Brain · doi:10.1093/brain/awh452 · Cited by 565 · see citing works

Inflammatory Mechanisms in Alzheimer's Disease: Inhibition of β-Amyloid-Stimulated Proinflammatory Responses and Neurotoxicity by PPARγ Agonists

Combs, C. K., Johnson, D. E., Karlo, J. C., Cannady, S. B., & Landreth, G. E. (2000) · The Journal of Neuroscience · doi:10.1523/jneurosci.20-02-00558.2000 · Cited by 483 · see citing works

Anti-Inflammatory Drug Therapy Alters β-Amyloid Processing and Deposition in an Animal Model of Alzheimer's Disease

Yan, Q., Zhang, J., Liu, H., Babu-Khan, S., Vassar, R., Biere, A. L., Citron, M., & Landreth, G. (2003) · The Journal of Neuroscience · doi:10.1523/jneurosci.23-20-07504.2003 · Cited by 469 · see citing works

The NR4A Subgroup: Immediate Early Response Genes with Pleiotropic Physiological Roles

Maxwell, M., & Muscat, G. E. O. (2006) · Nuclear Receptor Signaling · doi:10.1621/nrs.04002 · Cited by 447 · see citing works

The retinoid X receptors and their ligands

Dawson, M. I., & Xia, Z. (2011) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2011.09.014 · Cited by 389 · see citing works

Protection by pioglitazone in the MPTP model of Parkinson's disease correlates with IκBα induction and block of NFκB and iNOS activation

Dehmer, T., Heneka, M. T., Sastre, M., DICHGANS, J., & Schulz, J. B. (2003) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2003.02210.x · Cited by 382 · see citing works

Protective action of the peroxisome proliferator‐activated receptor‐γ agonist pioglitazone in a mouse model of Parkinson's disease

Breidert, T., Callebert, J., Heneka, M. T., Landreth, G. E., Launay, J., & Hirsch, É. C. (2002) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2002.00990.x · Cited by 375 · see citing works

Nonsteroidal anti-inflammatory drugs repress β-secretase gene promoter activity by the activation of PPARγ

Sastre, M., Dewachter, I., Rossner, S., Bogdanovic, N., Rosen, E., Borghgraef, P., Evert, B. O., Dumitrescu-Ozimek, L., Thal, D. R., Landreth, G., et al. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0503839103 · Cited by 373 · see citing works

PPAR-δ senses and orchestrates clearance of apoptotic cells to promote tolerance

Mukundan, L., Odegaard, J. I., Morel, C. R., Heredia, J. E., Mwangi, J. W., Ricardo-Gonzalez, R. R., Goh, Y. P. S., Eagle, A. R., Dunn, S. E., Awakuni, J. U. H., et al. (2009) · Nature Medicine · doi:10.1038/nm.2048 · Cited by 368 · see citing works

Rosiglitazone Monotherapy in Mild-to-Moderate Alzheimer’s Disease: Results from a Randomized, Double-Blind, Placebo-Controlled Phase III Study

Gold, M., Alderton, C., Zvartau-Hind, M., Egginton, S., Saunders, A. M., Irizarry, M., Craft, S., Landreth, G., Linnamägi, Ü., & Sawchak, S. (2010) · Dementia and Geriatric Cognitive Disorders · doi:10.1159/000318845 · Cited by 361 · see citing works

Attenuation of neuroinflammation and Alzheimer's disease pathology by liver x receptors

Zelcer, N., Khanlou, N., Clare, R., Jiang, Q., Reed-Geaghan, E. G., Landreth, G. E., Vinters, H. V., & Tontonoz, P. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0701096104 · Cited by 358 · see citing works

Mechanisms Underlying the Rapid Peroxisome Proliferator-Activated Receptor-γ-Mediated Amyloid Clearance and Reversal of Cognitive Deficits in a Murine Model of Alzheimer's Disease

Mandrekar-Colucci, S., Karlo, J. C., & Landreth, G. E. (2012) · The Journal of Neuroscience · doi:10.1523/jneurosci.5268-11.2012 · Cited by 355 · see citing works

Inflammation, defective insulin signaling, and neuronal dysfunction in Alzheimer's disease

Ferreira, S. T., Clarke, J. R., Bomfim, T. R., & Felice, F. G. D. (2014) · Alzheimer s & Dementia · doi:10.1016/j.jalz.2013.12.010 · Cited by 354 · see citing works

Cellular expression of the immediate early transcription factors Nurr1 and NGFI-B suggests a gene regulatory role in several brain regions including the nigrostriatal dopamine system

Zetterström, R. H., Williams, R., Perlmann, T., & Olson, L. (1996) · Molecular Brain Research · doi:10.1016/0169-328x(96)00074-5 · Cited by 340 · see citing works

PPARγ/RXRα-Induced and CD36-Mediated Microglial Amyloid-β Phagocytosis Results in Cognitive Improvement in Amyloid Precursor Protein/Presenilin 1 Mice

Yamanaka, M., Ishikawa, T., Griep, A., Axt, D., Kummer, M. P., & Heneka, M. T. (2012) · The Journal of Neuroscience · doi:10.1523/jneurosci.1569-12.2012 · Cited by 326 · see citing works

Therapeutic rescue of neurodegeneration in experimental type 3 diabetes: Relevance to Alzheimer's disease

de la Monte, S. M., Tong, M., Lester-Coll, N. H., Plater, M. E., & Wands, J. R. (2006) · Journal of Alzheimer s Disease · doi:10.3233/jad-2006-10113 · Cited by 324 · see citing works

Rosiglitazone attenuates learning and memory deficits in Tg2576 Alzheimer mice

Pedersen, W. A., McMillan, P. J., Kulstad, J. J., Leverenz, J. B., Craft, S., & Haynatzki, G. R. (2006) · Experimental Neurology · doi:10.1016/j.expneurol.2006.01.018 · Cited by 321 · see citing works

Nuclear receptors in macrophage biology: at the crossroads of lipid metabolism and inflammation.

Castrillo, A., & Tontonoz, P. (2004) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cellbio.20.012103.134432 · Cited by 320 · see citing works

Transgenic expression and activation of PGC-1α protect dopaminergic neurons in the MPTP mouse model of Parkinson’s disease

Mudó, G., Mäkelä, J., Liberto, V. D., Tselykh, T. V., Olivieri, M., Piepponen, P., Eriksson, O., Mälkiä, A., Bonomo, A., Kairisalo, M., et al. (2012) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-011-0850-z · Cited by 315 · see citing works

α-Synuclein–Induced Down-Regulation of Nurr1 Disrupts GDNF Signaling in Nigral Dopamine Neurons

Decressac, M., Kadkhodaei, B., Mattsson, B., Laguna, A., Perlmann, T., & Björklund, A. (2012) · Science Translational Medicine · doi:10.1126/scitranslmed.3004676 · Cited by 292 · see citing works

Activation of Wnt signaling by lithium and rosiglitazone reduced spatial memory impairment and neurodegeneration in brains of an APPswe/PSEN1ΔE9 mouse model of Alzheimer's disease

Toledo, E. M., & Inestrosa, N. C. (2009) · Molecular Psychiatry · doi:10.1038/mp.2009.72 · Cited by 290 · see citing works

Liver X receptors in the central nervous system: From lipid homeostasis to neuronal degeneration

Wang, L., Schuster, G. U., Hultenby, K. R., Zhang, Q., Andersson, S., & Gustafsson, J.-Α. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.172510899 · Cited by 286 · see citing works

The Liver X Receptor Ligand T0901317 Decreases Amyloid β Production in Vitro and in a Mouse Model of Alzheimer's Disease

Koldamova, R. P., Lefterov, I. M., Staufenbiel, M., Wolfe, D., Huang, S., Glorioso, J. C., Walter, M., Roth, M. G., & Lazo, J. S. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m411420200 · Cited by 279 · see citing works

PPARγ Agonists as Therapeutics for the Treatment of Alzheimer's Disease

Landreth, G. E., Jiang, Q., Mandrekar, S., & Heneka, M. T. (2008) · Neurotherapeutics · doi:10.1016/j.nurt.2008.05.003 · Cited by 277 · see citing works

Differential Expression of Cholesterol Hydroxylases in Alzheimer's Disease

Brown, J. A., Theisler, C. M., Silberman, S., Magnuson, D. J., Gottardi-Littell, N. R., Lee, J. M., Yager, D., Crowley, J., Sambamurti, K., Rahman, M. M., et al. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m402324200 · Cited by 268 · see citing works

Cerebrovascular Effects of Apolipoprotein E: Implications for Alzheimer Disease

Zlokovic, B. V. (2013) · JAMA Neurology · doi:10.1001/jamaneurol.2013.2152 · Cited by 263 · see citing works

Complete Rescue of Cerebrovascular Function in Aged Alzheimer's Disease Transgenic Mice by Antioxidants and Pioglitazone, a Peroxisome Proliferator-Activated Receptor γ Agonist

Nicolakakis, N., Aboulkassim, T., Ongali, B., Lecrux, C., Fernandes, P., Rosa-Neto, P., Tong, X.-K., & Hamel, E. (2008) · The Journal of Neuroscience · doi:10.1523/jneurosci.3348-08.2008 · Cited by 262 · see citing works

Coordination of inflammation and metabolism by PPAR and LXR nuclear receptors

Hong, C., & Tontonoz, P. (2008) · Current Opinion in Genetics & Development · doi:10.1016/j.gde.2008.07.016 · Cited by 253 · see citing works

Cooperative NCoR/SMRT interactions establish a corepressor-based strategy for integration of inflammatory and anti-inflammatory signaling pathwaysPreprint

Ghisletti, S., Huang, W. J. M., Jepsen, K., Benner, C. W., Hardiman, G., Rosenfeld, M. G., & Glass, C. K. (2009) · Genes & Development · doi:10.1101/gad.1773109 · Cited by 249 · see citing works

The LXR agonist TO901317 selectively lowers hippocampal Aβ42 and improves memory in the Tg2576 mouse model of Alzheimer's disease

Riddell, D. R., Zhou, H., Comery, T. A., Kouranova, E., Lo, C. F., Warwick, H. K., Ring, R. H., Kirksey, Y., Aschmies, S., Xu, J., et al. (2007) · Molecular and Cellular Neuroscience · doi:10.1016/j.mcn.2007.01.011 · Cited by 244 · see citing works

Selectively Reduced Expression of Synaptic Plasticity-Related Genes in Amyloid Precursor Protein + Presenilin-1 Transgenic Mice

Dickey, C. A., Loring, J. F., Montgomery, J., Gordon, M. N., Eastman, P. S., & Morgan, D. (2003) · The Journal of Neuroscience · doi:10.1523/jneurosci.23-12-05219.2003 · Cited by 242 · see citing works

Microglia: A new frontier for synaptic plasticity, learning and memory, and neurodegenerative disease research

Morris, G. P., Clark, I. A., Zinn, R., & Vissel, B. (2013) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2013.07.002 · Cited by 236 · see citing works

Rosiglitazone rescues memory impairment in Alzheimer’s transgenic mice: Mechanisms involving a reduced amyloid and tau pathology

Escribano, L., Simón, A.-M., Gimeno, E., Cuadrado-Tejedor, M., López de Maturana, R., García-Osta, A., Ricobaraza, A., Pérez-Mediavilla, A., Del Río, J., & Frechilla, D. (2010) · Neuropsychopharmacology · doi:10.1038/npp.2010.32 · Cited by 235 · see citing works

NURR1 in Parkinson disease—from pathogenesis to therapeutic potential

Decressac, M., Volakakis, N., Björklund, A., & Perlmann, T. (2013) · Nature Reviews Neurology · doi:10.1038/nrneurol.2013.209 · Cited by 234 · see citing works

The Oral Antidiabetic Pioglitazone Protects from Neurodegeneration and Amyotrophic Lateral Sclerosis-Like Symptoms in Superoxide Dismutase-G93A Transgenic Mice

Schütz, B., Reimann, J., Dumitrescu‐Ozimek, L., Kappes‐Horn, K., Landreth, G. E., Schürmann, B., Zimmer, A., & Heneka, M. T. (2005) · Journal of Neuroscience · doi:10.1523/jneurosci.2038-05.2005 · Cited by 225 · see citing works

Nuclear Receptors in Lipid Metabolism: Targeting the Heart of Dyslipidemia

Beaven, S. W., & Tontonoz, P. (2006) · Annual Review of Medicine · doi:10.1146/annurev.med.57.121304.131428 · Cited by 225 · see citing works

PGC-1α, mitochondrial dysfunction, and Huntington's disease

Johri, A., Chandra, A., & Beal, M. F. (2013) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2013.04.016 · Cited by 223 · see citing works

The Immune System as a Sensor of the Metabolic State

Odegaard, J. I., & Chawla, A. (2013) · Immunity · doi:10.1016/j.immuni.2013.04.001 · Cited by 215 · see citing works

Peroxisome proliferator-activated receptor-gamma agonist extends survival in transgenic mouse model of amyotrophic lateral sclerosis

Kiaei, M., KIPIANI, K., CHEN, J., Calingasan, N. Y., & Beal, M. F. (2004) · Experimental Neurology · doi:10.1016/j.expneurol.2004.10.007 · Cited by 215 · see citing works

The immunology of neurodegeneration

Czirr, E., & Wyss‐Coray, T. (2012) · Journal of Clinical Investigation · doi:10.1172/jci58656 · Cited by 211 · see citing works

Regulation of Cholesterol Homeostasis by the Liver X Receptors in the Central Nervous System

Whitney, K. D., Watson, M. A., Collins, J. L., Benson, W. G., Stone, T. M., Numerick, M. J., Tippin, T. K., Wilson, J. G., Winegar, D. A., & Kliewer, S. A. (2002) · Molecular Endocrinology · doi:10.1210/mend.16.6.0835 · Cited by 211 · see citing works

In vivo activation of PPAR target genes by RXR homodimers

IJpenberg, A., Tan, N. S., Gelman, L., Kersten, S., Seydoux, J., Xu, J., METZGER, D., Canaple, L., Chambon, P., Wahli, W., et al. (2004) · The EMBO Journal · doi:10.1038/sj.emboj.7600209 · Cited by 208 · see citing works

PPAR‐gamma‐mediated neuroprotection in a chronic mouse model of Parkinson’s disease

Schintu, N., Frau, L., Ibba, M., Caboni, P., Garau, A., Carboni, E., & Carta, A. R. (2009) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2009.06657.x · Cited by 200 · see citing works

ATP-binding Cassette Transporter A1 Mediates the Beneficial Effects of the Liver X Receptor Agonist GW3965 on Object Recognition Memory and Amyloid Burden in Amyloid Precursor Protein/Presenilin 1 Mice*

Donkin, J. J., Stukas, S., Hirsch-Reinshagen, V., Namjoshi, D., Wilkinson, A., May, S., Chan, J., Fan, J., Collins, J., & Wellington, C. L. (2010) · Journal of Biological Chemistry · doi:10.1074/jbc.m110.108100 · Cited by 200 · see citing works

Peroxisome Proliferator-Activated Receptor δ Regulation of miR-15a in Ischemia-Induced Cerebral Vascular Endothelial Injury

Yin, K., Deng, Z., Hamblin, M., Xiang, Y., Huang, H., Zhang, J., Jiang, X., Wang, Y., & Chen, Y. E. (2010) · Journal of Neuroscience · doi:10.1523/jneurosci.0780-10.2010 · Cited by 196 · see citing works

Molecular Pathways: The Role of NR4A Orphan Nuclear Receptors in Cancer

Mohan, H. M., Aherne, C. M., Rogers, A. C., Baird, A. W., Winter, D. C., & Murphy, E. P. (2012) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-11-2953 · Cited by 188 · see citing works

The PPAR-γ agonist pioglitazone modulates inflammation and induces neuroprotection in parkinsonian monkeys

Swanson, C. R., Joers, V. L., Bondarenko, V., Brunner, K. G., Simmons, H. A., Ziegler, T. E., Kemnitz, J. W., Johnson, J. A., & Emborg, M. E. (2011) · Journal of Neuroinflammation · doi:10.1186/1742-2094-8-91 · Cited by 187 · see citing works

Thiazolidinediones and Rexinoids Induce Peroxisome Proliferator-Activated Receptor-Coactivator (PGC)-1α Gene Transcription: An Autoregulatory Loop Controls PGC-1α Expression in Adipocytes via Peroxisome Proliferator-Activated Receptor-γ Coactivation

Hondares, E., Mora, O., Yubero, P., de la Concepción, M. L. R., Iglesias, R., Giralt, M., & Villarroya, F. (2006) · Endocrinology · doi:10.1210/en.2006-0070 · Cited by 183 · see citing works

Critical Role of Astroglial Apolipoprotein E and Liver X Receptor-α Expression for Microglial Aβ Phagocytosis

Terwel, D., Steffensen, K. R., Verghese, P. B., Kummer, M. P., Gustafsson, J.-Å., Holtzman, D. M., & Heneka, M. T. (2011) · The Journal of Neuroscience · doi:10.1523/jneurosci.6546-10.2011 · Cited by 181 · see citing works

Effect of anti-inflammatory agents on transforming growth factor beta over-expressing mouse brains: a model revised

Lacombe, P., Mathews, P. M., Schmidt, S., Breidert, T., Heneka, M., Landreth, G., Feinstein, D. L., & Galea, E. (2004) · Journal of Neuroinflammation · doi:10.1186/1742-2094-1-11 · Cited by 179 · see citing works

Liver X Receptor Agonist Treatment Ameliorates Amyloid Pathology and Memory Deficits Caused by High-Fat Diet in APP23 Mice

Fitz, N. F., Cronican, A., Pham, T., Fogg, A., Fauq, A. H., Chapman, R., Lefterov, I., & Koldamova, R. (2010) · The Journal of Neuroscience · doi:10.1523/jneurosci.1051-10.2010 · Cited by 175 · see citing works

The Role of Peroxisome Proliferator-Activated Receptor-γ (PPARγ) in Alzheimer’s Disease

Jiang, Q., Heneka, M. T., & Landreth, G. E. (2008) · CNS Drugs · doi:10.2165/00023210-200822010-00001 · Cited by 174 · see citing works

Lack of Genetic Associations of PPAR-γ and PGC-1α with Alzheimer's Disease and Parkinson's Disease with Dementia

Shibata, N., Motoi, Y., Tomiyama, H., Ohnuma, T., Kuerban, B., Tomson, K., Komatsu, M., Shimazaki, H., Hattori, N., & Arai, H. (2013) · Dementia and Geriatric Cognitive Disorders Extra · doi:10.1159/000351419 · Cited by 171 · see citing works

Inactivation of liver X receptor β leads to adult-onset motor neuron degeneration in male mice

Andersson, S., Gustafsson, N., Warner, M. N., & Gustafsson, J.-Α. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0500634102 · Cited by 168 · see citing works

NR4A orphan nuclear receptors as mediators of CREB-dependent neuroprotection

Volakakis, N., Kadkhodaei, B., Joodmardi, E., Wallis, K., Panman, L., Silvaggi, J., Spiegelman, B. M., & Perlmann, T. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1007088107 · Cited by 167 · see citing works

Omega-3 fatty acids in anti-inflammation (pro-resolution) and GPCRs

Im, D. (2012) · Progress in Lipid Research · doi:10.1016/j.plipres.2012.02.003 · Cited by 163 · see citing works

Differential SUMOylation of LXRα and LXRβ Mediates Transrepression of STAT1 Inflammatory Signaling in IFN-γ-Stimulated Brain Astrocytes

Lee, J. H., Park, S. M., Kim, O. S., Lee, C. S., Woo, J. H., Park, S. J., Joe, E.-H., & Jou, I. (2009) · Molecular Cell · doi:10.1016/j.molcel.2009.07.021 · Cited by 161 · see citing works

Pharmacologic activation of mitochondrial biogenesis exerts widespread beneficial effects in a transgenic mouse model of Huntington's disease

Johri, A., Calingasan, N. Y., Hennessey, T., Sharma, A., Yang, L., Wille, E. J., Chandra, A., & Beal, M. F. (2011) · Human Molecular Genetics · doi:10.1093/hmg/ddr541 · Cited by 161 · see citing works

Insulin and Alzheimer's Disease: Untangling the Web

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Nuclear receptors, mitochondria and lipid metabolism

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Liver X Receptors and Oxysterols Promote Ventral Midbrain Neurogenesis In Vivo and in Human Embryonic Stem Cells

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Comment on “ApoE-directed therapeutics rapidly clear β-amyloid and reverse deficits in AD mouse models.”

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Liver X receptor β (LXRβ): A link between β-sitosterol and amyotrophic lateral sclerosis–Parkinson's dementia

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Rosiglitazone reverses memory decline and hippocampal glucocorticoid receptor down-regulation in an Alzheimer’s disease mouse model

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Sensory Network Dysfunction, Behavioral Impairments, and Their Reversibility in an Alzheimer's β-Amyloidosis Mouse Model

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Brain endogenous liver X receptor ligands selectively promote midbrain neurogenesis

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In vivo measurement of apolipoprotein E from the brain interstitial fluid using microdialysis

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Comment on “ApoE-Directed Therapeutics Rapidly Clear β-Amyloid and Reverse Deficits in AD Mouse Models”

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-Amyloid Disrupts Activity-Dependent Gene Transcription Required for Memory through the CREB Coactivator CRTC1

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Nuclear receptors as therapeutic targets for Alzheimer's disease

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Protective effects of a peroxisome proliferator-activated receptor-β/δ agonist in experimental autoimmune encephalomyelitis

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Neuroprotective effects of PPAR ‐γ agonist rosiglitazone in N171‐82Q mouse model of Huntington's disease

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The PPARγ agonist pioglitazone is effective in the MPTP mouse model of Parkinson's disease through inhibition of monoamine oxidase B

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Low Dose Bexarotene Treatment Rescues Dopamine Neurons and Restores Behavioral Function in Models of Parkinson’s Disease

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Liver X receptor and retinoid X receptor agonists inhibit inflammatory responses of microglia and astrocytes

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Cognitive Enhancement with Rosiglitazone Links the Hippocampal PPARγ and ERK MAPK Signaling Pathways

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A PPARdelta Agonist Reduces Amyloid Burden and Brain Inflammation in a Transgenic Mouse Model of Alzheimers Disease

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Beneficial effects of pioglitazone on cognitive impairment in MPTP model of Parkinson's disease

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Crtc1 Activates a Transcriptional Program Deregulated at Early Alzheimer's Disease-Related Stages

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Multiple signaling pathways regulate the transcriptional activity of the orphan nuclear receptor NURR1

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Liver X receptor β protects dopaminergic neurons in a mouse model of Parkinson disease

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Modulation of energy deficiency in Huntington's disease via activation of the peroxisome proliferator-activated receptor gamma

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PPAR-α agonist fenofibrate protects against the damaging effects of MPTP in a rat model of Parkinson's disease

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Drug Insight: effects mediated by peroxisome proliferator-activated receptor-γ in CNS disorders

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The orphan nuclear receptor Nurr1 restricts the proliferation of haematopoietic stem cells

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Expression profiling in APP23 mouse brain: inhibition of Aβ amyloidosis and inflammation in response to LXR agonist treatment

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Rosiglitazone reversal of Tg2576 cognitive deficits is independent of peripheral gluco-regulatory status

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Essential role for DNA-PK-mediated phosphorylation of NR4A nuclear orphan receptors in DNA double-strand break repairPreprint

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Treatment with bexarotene, a compound that increases apolipoprotein-E, provides no cognitive benefit in mutant APP/PS1 mice

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Lipid-lowering drugs in the MPTP mouse model of Parkinson's disease: Fenofibrate has a neuroprotective effect, whereas bezafibrate and HMG-CoA reductase inhibitors do not

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Bexarotene nanocrystal—Oral and parenteral formulation development, characterization and pharmacokinetic evaluation

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Bezafibrate administration improves behavioral deficits and tau pathology in P301S mice

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Neuroprotective actions of noradrenaline: effects on glutathione synthesis and activation of peroxisome proliferator activated receptor delta

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Pioglitazone Improves Reversal Learning and Exerts Mixed Cerebrovascular Effects in a Mouse Model of Alzheimer’s Disease with Combined Amyloid-β and Cerebrovascular Pathology

Papadopoulos, P., Rosa‐Neto, P., Rochford, J. M., & Hamel, É. (2013) · PLoS ONE · doi:10.1371/journal.pone.0068612 · Cited by 75 · see citing works

Research Resource: Transcriptome Profiling of Genes Regulated by RXR and Its Permissive and Nonpermissive Partners in Differentiating Monocyte-Derived Dendritic Cells

Széles, L., Póliska, S., Nagy, G., Szatmári, I., Szántó, A., Pap, A., Lindstedt, M., Santegoets, S. J. A. M., Rühl, R., Dezsö, B., et al. (2010) · Molecular Endocrinology · doi:10.1210/me.2010-0215 · Cited by 74 · see citing works

Response to Comments on “ApoE-Directed Therapeutics Rapidly Clear β-Amyloid and Reverse Deficits in AD Mouse Models”

Landreth, G. E., Cramer, P. E., Lakner, M. M., Cirrito, J. R., Wesson, D. W., Brunden, K. R., & Wilson, D. A. (2013) · Science · doi:10.1126/science.1234114 · Cited by 73 · see citing works

Increased Infarct Size and Lack of Hyperphagic Response after Focal Cerebral Ischemia in Peroxisome Proliferator-Activated Receptor β-Deficient Mice

Arsenijevic, D., de Bilbao, F., Plamondon, J., Paradis, E., Vallet, P. G., Richard, D., Langhans, W., & Giannakopoulos, P. (2005) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1038/sj.jcbfm.9600200 · Cited by 71 · see citing works

Effects of long-term treatment with pioglitazone on cognition and glucose metabolism of PS1-KI, 3xTg-AD, and wild-type mice

Masciopinto, F., Pietro, N. D., Corona, C., Bomba, M., Pipino, C., Curcio, M., Castelnuovo, A. F. D., Ciavardelli, D., Silvestri, E., Canzoniero, L. M. T., et al. (2012) · Cell Death and Disease · doi:10.1038/cddis.2012.189 · Cited by 71 · see citing works

Modulating Microglia Activity with PPAR-γ Agonists: A Promising Therapy for Parkinson’s Disease?

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Rosiglitazone, a PPAR-γ agonist, protects against striatal dopaminergic neurodegeneration induced by 6-OHDA lesions in the substantia nigra of rats

Lee, E. Y., Lee, J. E., Park, J. H., Shin, I. C., & Koh, H. C. (2012) · Toxicology Letters · doi:10.1016/j.toxlet.2012.07.016 · Cited by 69 · see citing works

Pharmacological manipulation of peroxisome proliferator-activated receptor γ (PPARγ) reveals a role for anti-oxidant protection in a model of Parkinson's disease

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Peroxisome Proliferator‐Activated Receptor‐γ in Amyotrophic Lateral Sclerosis and Huntington′s Disease

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The NR4A orphan nuclear receptors mediate transcription-dependent hippocampal synaptic plasticity

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Nuclear Import and Export Signals Control the Subcellular Localization of Nurr1 Protein in Response to Oxidative Stress*

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Peroxisome Proliferators Reduce Spatial Memory Impairment, Synaptic Failure, and Neurodegeneration in Brains of a Double Transgenic Mice Model of Alzheimer's Disease

Inestrosa, N. C., Carvajal, F. J., Zolezzi, J. M., Tapia‐Rojas, C., Serrano, F. G., Karmelic, D., Toledo, E. M., Toro, A., Toro, J., & Santos, M. J. (2013) · Journal of Alzheimer s Disease · doi:10.3233/jad-2012-120397 · Cited by 62 · see citing works

Effects of pioglitazone and retinoic acid in a rotenone model of Parkinson's disease

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The nuclear receptor PPARγ as a therapeutic target for cerebrovascular and brain dysfunction in Alzheimer's disease

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Nurr1 Protein Is Required for N-Methyl-d-aspartic Acid (NMDA) Receptor-mediated Neuronal Survival

Barneda‐Zahonero, B., Servitja, J., Badiola, N., Miñano-Molina, A. J., Fadó, R., Saura, C. A., & Rodrı́guez-Álvarez, J. (2012) · Journal of Biological Chemistry · doi:10.1074/jbc.m111.272427 · Cited by 60 · see citing works

Nuclear Orphan Receptor NR4A2 Modulates Fatty Acid Oxidation Pathways in Colorectal Cancer

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Effects of the PPARγ activator pioglitazone on p38 MAP kinase and IκBα in the spinal cord of a transgenic mouse model of amyotrophic lateral sclerosis

Shibata, N., Kawaguchi, M., Yamamoto, T., Toi, S., Hirano, A., & Kobayashi, M. (2008) · Neuropathology · doi:10.1111/j.1440-1789.2008.00890.x · Cited by 56 · see citing works

Rosiglitazone Improves Spatial Memory and Decreases Insoluble Aβ1–42 in APP/PS1 Mice

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Liver X receptor activation attenuates inflammatory response and protects cholinergic neurons in APP/PS1 transgenic mice

Cui, W., Sun, Y., Wang, Z., Xu, C., Peng, Y., & Li, R. (2012) · Neuroscience · doi:10.1016/j.neuroscience.2012.02.047 · Cited by 56 · see citing works

Cognitive Enhancing Treatment with a PPARγ Agonist Normalizes Dentate Granule Cell Presynaptic Function in Tg2576 APP Mice

Nenov, M. N., Laezza, F., Haidacher, S. J., Zhao, Y., Sadygov, R. G., Starkey, J. M., Spratt, H. M., Luxon, B. A., Dineley, K. T., & Denner, L. A. (2014) · Journal of Neuroscience · doi:10.1523/jneurosci.3413-13.2014 · Cited by 54 · see citing works

Vascular PPARδ Protects Against Stroke-Induced Brain Injury

Yin, K., Deng, Z., Hamblin, M., Zhang, J., & Chen, Y. (2011) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.110.221267 · Cited by 52 · see citing works

NR4A orphan nuclear receptors in glucose homeostasis: A minireview

Close, A. F., Rouillard, C., & Buteau, J. (2013) · Diabetes & Metabolism · doi:10.1016/j.diabet.2013.07.005 · Cited by 52 · see citing works

Differential susceptibility to the PPAR-γ agonist pioglitazone in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and 6-hydroxydopamine rodent models of Parkinson's disease

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A peroxisome proliferator-activated receptor-δ agonist provides neuroprotection in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson’s disease

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MRI monitoring of focal cerebral ischemia in peroxisome proliferator‐activated receptor (PPAR)‐deficient mice

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Full and partial peroxisome proliferation-activated receptor-gamma agonists, but not delta agonist, rescue of dopaminergic neurons in the 6-OHDA Parkinsonian model is associated with inhibition of microglial activation and MMP expression

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Peroxisome proliferator‐activated receptor‐γ cofactors in neurodegeneration

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Recent advances in nuclear receptors-mediated health benefits of blueberry

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Molecular docking, dynamics, and pharmacology studies on bexarotene as an agonist of ligand‐activated transcription factors, retinoid X receptors

Chitranshi, N., Dheer, Y., Kumar, S., Graham, S. L., & Gupta, V. (2019) · Journal of Cellular Biochemistry · doi:10.1002/jcb.28455 · Cited by 22 · see citing works

Chiral Dihydrobenzofuran Acids Show Potent Retinoid X Receptor–Nuclear Receptor Related 1 Protein Dimer Activation

Sundén, H., Schäfer, A., Scheepstra, M., Leysen, S., Malo, M., Ma, J., Burstein, E. S., Ottmann, C., Brunsveld, L., & Olsson, R. (2016) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.5b01702 · Cited by 21 · see citing works

Activation of PPAR δ: from computer modelling to biological effects

Kahremany, S., Livne, A., Gruzman, A., Senderowitz, H., & Sasson, S. (2014) · British Journal of Pharmacology · doi:10.1111/bph.12950 · Cited by 20 · see citing works

Nuclear receptor Nr1d1 alleviates asthma by abating GATA3 gene expression and Th2 cell differentiation

Tiwari, D., Ahuja, N., Kumar, S. R., Kalra, R., Nanduri, R., Gupta, S. D., Khare, A. K., Bhagyaraj, E., Arora, R., & Gupta, P. K. (2022) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-022-04323-0 · Cited by 18 · see citing works

Liver X receptors: From pharmacology to nanoparticle-based drug delivery

Hua, X., & Wei, X. (2023) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2023.175953 · Cited by 14 · see citing works

Nuclear receptors of NR1 and NR4 subfamilies in the regulation of microglial functions and pathology

Katsuki, H. (2021) · Pharmacology Research & Perspectives · doi:10.1002/prp2.766 · Cited by 14 · see citing works

Manipulation of Hematopoietic Stem Cell Fate by Small Molecule Compounds

Zarrabi, M., Afzal, E., & Ebrahimi, M. (2018) · Stem Cells and Development · doi:10.1089/scd.2018.0091 · Cited by 13 · see citing works

Evidence that activation of nuclear peroxisome proliferator-activated receptor alpha (PPARα) modulates sleep homeostasis in rats

Murillo‐Rodríguez, E., Guzmán, K., Arankowsky‐Sandoval, G., Salas-Crisóstomo, M., Jiménez-Moreno, R., & Arias-Carrión, Ó. (2016) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2016.09.007 · Cited by 8 · see citing works

A Review of Neuroreceptors for Clinical and Experimental Neuropharmacology in Central Nervous System Disorders

McKarns, S. C. (2022) · Current Clinical Pharmacology · doi:10.2174/2772432817666220301104118 · Cited by 7 · see citing works

Empirical Analysis of Drug Targets for Nervous System Disorders

Mueller, L. G., Slusher, B. S., & Tsukamoto, T. (2024) · ACS Chemical Neuroscience · doi:10.1021/acschemneuro.3c00676 · Cited by 7 · see citing works

Type II nuclear receptors with potential role in Alzheimer disease

Muñoz-Cabrera, J., Adrián, S.-H., & Arboleda, G. (2021) · Molecular Aspects of Medicine · doi:10.1016/j.mam.2020.100940 · Cited by 7 · see citing works

Changes in lipid metabolism driven by steroid signalling modulate proteostasis in C. elegans

Gómez-Escribano, A. P., Mora‐Martínez, C., Roca, M., Walker, D. S., Panadero, J., Sequedo, M. D., Saini, R., Knölker, H., Blanca, J., Burguera, J. A., et al. (2023) · EMBO Reports · doi:10.15252/embr.202255556 · Cited by 7 · see citing works

Dichlorodiphenyltrichloroethane Impairs Amyloid Beta Clearance by Decreasing Liver X Receptor α Expression

Wu, D., Hu, Y., Song, M., & Li, G. (2021) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2021.634948 · Cited by 7 · see citing works

Liver X receptor agonists in central nervous system disorders: From neuroprotection to clinical challenges

Zhang, Q., Mao, J.-D., Wang, M., Chen, H., Wang, Q.-F., Zhang, K., Yang, L., Ma, X., Wang, C., & Wu, Y. (2025) · Neuroscience · doi:10.1016/j.neuroscience.2025.07.050 · Cited by 6 · see citing works

Saroglitazar, a PPAR α/γ agonist alleviates 3-Nitropropionic acid induced neurotoxicity in rats: Unveiling the underlying mechanisms

Jakkamsetti, M. S., Kolusu, A. S., Rongala, S., Arakareddy, B. P., Nori, L. P., & Samudrala, P. K. (2024) · NeuroToxicology · doi:10.1016/j.neuro.2024.09.004 · Cited by 4 · see citing works

Nuclear Receptor Networks as the Central Hub of Endocrine-Disrupting Chemical Neurotoxicity: A System Toxicology Perspective

Lu, Y., Ren, L., Yu, J., Zhang, T., & Zhang, J. (2025) · Environmental Science & Technology · doi:10.1021/acs.est.5c14620 · Cited by 4 · see citing works

Nr1h4 and Thrb ameliorate ER stress and provide protection in the MPTP mouse model of Parkinson’s

Ahuja, N., Gupta, S. D., Arora, R., Bhagyaraj, E., Tiwari, D., Kumar, S. R., & Gupta, P. K. (2024) · Life Science Alliance · doi:10.26508/lsa.202302416 · Cited by 4 · see citing works

Comprehensive characterization of a novel small-molecule activator for the nuclear receptor Nur77: Chemical, molecular, and biological insights

Reddy, A. T., Lakshmi, S. P., Nyunoya, T., & Reddy, R. C. (2024) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2024.176945 · Cited by 4 · see citing works

PPARα and PPARγ Signaling Is Enhanced in the Brain of the Naked Mole-Rat, a Mammal that Shows Intrinsic Neuroprotection from Oxygen Deprivation

Pergande, M. R., Amoroso, V. G., Nguyen, T. T. A., Li, W., Vice, E. N., Park, T. J., & Cologna, S. M. (2021) · Journal of Proteome Research · doi:10.1021/acs.jproteome.1c00131 · Cited by 4 · see citing works

Age-related changes in retinoic, docosahexaenoic and arachidonic acid modulation in nuclear lipid metabolism

Gaveglio, V. L., Pascual, A. C., Giusto, N. M., & Pasquaré, S. J. (2016) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2016.06.017 · Cited by 3 · see citing works

Liver X and thyroid hormone receptors in neurodegeneration

Warner, M. N., Song, X., & Gustafsson, J.-Å. (2024) · Genomic psychiatry : · doi:10.61373/gp024i.0073 · Cited by 2 · see citing works

Nurr1, Pitx3, and α7 nAChRs mRNA Expression in Nigral Tissue of Rats with Pedunculopontine Neurotoxic Lesion

Blanco-Lezcano, L., Alberti‐Amador, E., González-Fraguela, M. E., de Larrea, G. Z., Pérez‐Serrano, R. M., Jiménez-Luna, N. A., Sánchez, T. S., Turner, L. F., Rodríguez, D. C., & Hurtado, Y. V. (2019) · Medicina · doi:10.3390/medicina55100616 · Cited by 2 · see citing works

Large-scale genomic data-mining implicates dysregulated nuclear receptor-mediated signaling in mental illness

Donskov, J. G. (2021) · Journal of Translational Genetics and Genomics · doi:10.20517/jtgg.2021.12 · Cited by 2 · see citing works

Opposing steroid signals modulate protein homeostasis through deep changes in fat metabolism in Caenorhabditis elegansPreprint

Gómez-Escribano, A. P., Mora‐Martínez, C., Roca, M., Walker, D., Panadero, J., Sequedo, M. D., Saini, R., Knölker, H., Blanca, J., Burguera, J. A., et al. (2019) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/551580 · Cited by 2 · see citing works

Comprehensive Overview of Alzheimer’s Disease Neurodegeneration, from Amyloid-β to Neuroinflammatory Modulation

Zolezzi, J. M., & Inestrosa, N. C. (2017) · InTech eBooks · doi:10.5772/intechopen.69463 · Cited by 1 · see citing works

Sex Differences in Alzheimer’s Disease Pathogenesis

Jung, E. S., & Mook‐Jung, I. (2024) · Springer eBooks · doi:10.1007/978-981-97-0130-8_24 · Cited by 1 · see citing works

The PPARα Agonist Fenofibrate Reduces the Levels of Proinflammatory Cytokines in a Maternal Immune Activation Model of SchizophreniaPreprint

Mostallino, R., Santoni, M., Sagheddu, C., Serra, V., Orrù, V., Pistis, M., & Castelli, M. P. (2023) · Preprints.org · doi:10.20944/preprints202306.0539.v1

Evidence that an HDAC2-targeted ASO persistently upregulates cortical acetylcholine and dopamine signaling via a CREB | Gs positive feedback loopPreprint

Sanders, T. H. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.09.24.312264

RXR – centralny regulator wielu ścieżek sygnałowych w organizmie

Sołtys, K., Leszczyński, B., & Ożyhar, A. (2021) · Postępy Higieny i Medycyny Doświadczalnej · doi:10.2478/ahem-2021-0005

A administração repetida de um agonista do receptor ativado pelo proliferador de peroxissomos gama (PPARγ) reverte o prejuízo na extinção da memória de medo condicionado ao contexto em animais submetidos a um modelo de transtorno do estresse pós-traumático

Júnior, A. F. D. S. (2023) · doi:10.11606/d.17.2023.tde-10082023-090340

Entwicklung von chemischen Tools für nukleäre Rezeptoren

Arifi, S. (2023) · doi:10.21248/gups.81648

Nuclear receptors in age-related diseases: From mechanisms to drug discovery

Zhang, L., Li, X., Ren, C., Hao, Y., Deng, Y., Pan, H., Kim, Y.-B., Fan, S., Huang, C., Ge, G., et al. (2026) · Ageing Research Reviews · doi:10.1016/j.arr.2026.103125

Étude de la surexpression du récepteur activé par les proliférateurs de peroxysomes (PPAR) b/d spécifiquement dans les lymphocytes T : effet sur l’inflammation associée à l’obésité et à un choc septique

Menn, G. L. (2018) · theses.fr (ABES) · doi:10.70675/4f4e158ez7cc6z4598z98bcz08e195329545

BindingDB Entry 50047290: Chiral Dihydrobenzofuran Acids Show Potent Retinoid X Receptor-Nuclear Receptor Related 1 Protein Dimer Activation.

BindingDB (2017) · UC San Diego · doi:10.7270/q2x63pt7

Nuclear Receptors as Therapeutic Targets for Neurodegenerative Diseases: Lost in Translation

Moutinho, M., Codocedo, J. F., Puntambekar, S. S., & Landreth, G. E. (2018) · The Annual Review of Pharmacology and Toxicology · doi:10.1146/annurev-pharmtox-010818-021807 · Cited by 55 · see citing works

Targeting Nuclear Receptors in Neurodegeneration and Neuroinflammation

Willems, S., Zaienne, D., & Merk, D. (2021) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.1c00186 · Cited by 66 · see citing works

Recent Insights on the Role of Nuclear Receptors in Alzheimer’s Disease: Mechanisms and Therapeutic Application

Shan, X., Li, D., Yin, H., Tao, W., Zhou, L., Gao, Y. W., Xing, C., & Zhang, C. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26031207 · Cited by 7 · see citing works

Nuclear Receptors, Inflammation, and Neurodegenerative Diseases

Saijo, K., Crotti, A., & Glass, C. K. (2010) · Advances in immunology · doi:10.1016/s0065-2776(10)06002-5 · Cited by 41 · see citing works

Nuclear receptors as therapeutic targets for Alzheimer's disease

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