The DOI matches its Crossref record; 13 of the 13 references it cites were found in a registry or an index.
The Insulin-Like Growth Factor System and Its Pleiotropic Functions in Brain
Abstract
In recent years, much interest has been devoted to defining the role of the IGF system in the nervous system. The ubiquitous IGFs, their cell membrane receptors, and their carrier binding proteins, the IGFBPs, are expressed early in the development of the nervous system and are therefore considered to play a key role in these processes. In vitro studies have demonstrated that the IGF system promotes differentiation and proliferation and sustains survival, preventing apoptosis of neuronal and brain derived cells. Furthermore, studies of transgenic mice overexpressing components of the IGF system or mice with disruptions of the same genes have clearly shown that the IGF system plays a key role in vivo.
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Citations
Cites
IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice
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“IGFBP-1 is known to inhibit somatic linear growth, weight gain, tissue growth, and glucose metabolism (293).”
BackgroundRegulation of C. elegans Longevity by Specific Gustatory and Olfactory Neurons
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Erythropoietin as an antiapoptotic, tissue-protective cytokine
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“In addition, there is indirect evidence in rats of improved cognitive function after traumatic brain injury treated with IGF-I (432).”
BackgroundGrowth hormone as a neuronal rescue factor during recovery from CNS injury
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Self-citationThe role of insulin and insulin-like growth factor-I in mammalian ageing
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“ilarly effective in enhancing longevity (518), whereas in C.”
Background
Cited by
The many faces of insulin-like peptide signalling in the brain
Fernandez, A. M., & Torres-Alemán, I. (2012) · Nature reviews. Neuroscience · doi:10.1038/nrn3209 · Cited by 872
Moloney, A. M., Griffin, R. J., Timmons, S., O’Connor, R., Ravid, R., & O’Neill, C. (2010) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2008.04.002 · Cited by 764
Spatial memory is improved by aerobic and resistance exercise through divergent molecular mechanisms
Cassilhas, R. C., Lee, K. S., Fernandes, J., Oliveira, M. G. M., Tufik, S., Meeusen, R., & de Mello, M. T. (2012) · Neuroscience · doi:10.1016/j.neuroscience.2011.11.029 · Cited by 394
Physical exercise, neuroplasticity, spatial learning and memory
Cassilhas, R. C., Tufik, S., & de Mello, M. T. (2016) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-015-2102-0 · Cited by 340
Suh, H.-S., Zhao, M.-L., Derico, L., Choi, N., & Lee, S. C. (2013) · Journal of Neuroinflammation · doi:10.1186/1742-2094-10-37 · Cited by 226
Metadata
- Authors
- Russo, V. C., Gluckman, P. D., Feldman, E. L., & Werther, G. A.
- Venue
- Endocrine Reviews
- Publisher
- The Endocrine Society
- Published
- 2005-08-30
- Volume
- 26
- Issue
- 7
- Pages
- 916-943
- ISSN
- 0163-769X (ISSN-L)
- 1945-7189
- OpenAlex
- W2024977477
- Cited by
- 492
- References
- 13
- FWCI
- 13.14
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
