Corticotropin-releasing hormone directly stimulates cortisol and the cortisol biosynthetic pathway in human fetal adrenal cells

Maternal and Fetal Hypothalamic‐Pituitary‐Adrenal Axes During Pregnancy and Postpartum

MASTORAKOS, G., & ILIAS, I. (2003) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1290.016 · Cited by 621 · see citing works

Placental Estrogen Biosynthesis During Human Pregnancy1

SIITERI, P. K., & MACDONALD, P. C. (1966) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-26-7-751 · Cited by 479 · see citing works

Glucocorticoid stimulates expression of corticotropin-releasing hormone gene in human placenta.

Robinson, B. G., Emanuel, R. L., Frim, D. M., & Majzoub, J. A. (1988) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.85.14.5244 · Cited by 440 · see citing works

Plasma Corticotropin-Releasing Hormone Concentrations During Pregnancy and Parturition*

CAMPBELL, E. A., Linton, E. A., Wolfe, C. D. A., Scraggs, P. R., Jones, M. T., & Lowry, P. J. (1987) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-64-5-1054 · Cited by 386 · see citing works

Evidence for local stimulation of ACTH secretion by corticotropin-releasing factor in human placenta

Petraglia, F., Sawchenko, P. E., Rivier, J., & Vale, W. (1987) · Nature · doi:10.1038/328717a0 · Cited by 337 · see citing works

High Levels of Corticotropin-Releasing Hormone Immunoactivity in Maternal and Fetal Plasma during Pregnancy*

Goland, R., Wardlaw, S. L., Stark, R. I., Brown, L. S., & FRANTZ, A. G. (1986) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-63-5-1199 · Cited by 279 · see citing works

Effects of Adrenalectomy and Dexamethasone Administration on the Level of Prepro-Corticotropin-Releasing Factor Messenger Ribonucleic Acid (mRNA) in the Hypothalamus and Adrenocorticotropin/β-Lipotropin Precursor mRNA in the Pituitary in Rats*

Jingami, H., Matsukura, S., Numa, S., & Imura, H. (1985) · Endocrinology · doi:10.1210/endo-117-4-1314 · Cited by 271 · see citing works

Steroids Modulate Corticotropin-Releasing Hormone Production in Human Fetal Membranes and Placenta*

JONES, S. A., Brooks, A. N., & Challis, J. R. G. (1989) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-68-4-825 · Cited by 264 · see citing works

Corticotropin-Releasing Hormone Directly and Preferentially Stimulates Dehydroepiandrosterone Sulfate Secretion by Human Fetal Adrenal Cortical Cells

Smith, R., Mesiano, S. A., Chan, E., Brown, S. A., & Jaffe, R. B. (1998) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.83.8.5020 · Cited by 249 · see citing works

Plasma ACTH Levels in the Human Fetus and Neonate as Related to Age and Parturition1

Winters, A. J., Oliver, C., COLSTON, C., MacDonald, P. C., & Porter, J. C. (1974) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-39-2-269 · Cited by 160 · see citing works

Glucocorticoid Regulation of Human and Ovine Parturition: The Relationship Between Fetal Hypothalamic-Pituitary-Adrenal Axis Activation and Intrauterine Prostaglandin Production

Whittle, W. L., Patel, F. A., Alfaidy, N., Holloway, A. C., Fraser, M., Gyomorey, S., Lye, S. J., Gibb, W., & Challis, J. R. G. (2001) · Biology of Reproduction · doi:10.1095/biolreprod64.4.1019 · Cited by 157 · see citing works

3β-Hydroxysteroid Dehydrogenase/Isomerase in the Fetal Zone and Neocortex of the Human Fetal Adrenal Gland*

Doody, K. M., Carr, B. R., Rainey, W. E., BYRD, W., Murry, B. A., Strickler, R. C., Thomas, J. L., & Mason, J. I. (1990) · Endocrinology · doi:10.1210/endo-126-5-2487 · Cited by 152 · see citing works

Proliferation and Apoptosis in the Human Adrenal Cortex during the Fetal and Perinatal Periods: Implications for Growth and Remodeling1

Spencer, S. J., Mesiano, S. A., Lee, J. Y., & Jaffe, R. B. (1999) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.84.3.5513 · Cited by 134 · see citing works

Localization of cytochrome P450 cholesterol side-chain cleavage, cytochrome P450 17 alpha-hydroxylase/17, 20-lyase, and 3 beta-hydroxysteroid dehydrogenase isomerase steroidogenic enzymes in human and rhesus monkey fetal adrenal glands: reappraisal of functional zonation.

Mesiano, S. A., Coulter, C. L., & Jaffe, R. B. (1993) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.77.5.8077311 · Cited by 133 · see citing works

Proliferation and Apoptosis in the Human Adrenal Cortex during the Fetal and Perinatal Periods: Implications for Growth and Remodeling

Spencer, S. J. (1999) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.84.3.1110 · Cited by 120 · see citing works

A SPECIFIC CARRIER SUBSTANCE FOR HUMAN CORTICOTROPHIN RELEASING FACTOR IN LATE GESTATIONAL MATERNAL PLASMA WHICH COULD MASK THE ACTH‐RELEASING ACTIVITY

Linton, E. A., Wolfe, C. D. A., Behan, D. P., & Lowry, P. J. (1988) · Clinical Endocrinology · doi:10.1111/j.1365-2265.1988.tb01218.x · Cited by 117 · see citing works

Corticotropin-releasing hormone and related pituitary-adrenal axis hormones in fetal and maternal blood during the second half of pregnancy

Lockwood, C. J., Radunović, N. V., Nastic, D., Petković, S. V., Aigner, S., & Berkowitz, G. S. (1996) · Journal of Perinatal Medicine · doi:10.1515/jpme.1996.24.3.243 · Cited by 113 · see citing works

Human fetal serum cortisol levels related to gestational age: Evidence of a midgestational fall and a steep late gestational rise, independent of sex or mode of delivery

Murphy, B. E. P. (1982) · American Journal of Obstetrics and Gynecology · doi:10.1016/0002-9378(82)90579-8 · Cited by 112 · see citing works

Temporal and spatial distribution of corticosteroidogenic enzymes immunoreactivity in developing human adrenal

Narasaka, T., Suzuki, T., Moriya, T., & Sasano, H. (2001) · Molecular and Cellular Endocrinology · doi:10.1016/s0303-7207(00)00445-7 · Cited by 109 · see citing works

Colocalization of P450c17 and Cytochrome b5 in Androgen-Synthesizing Tissues of the Human1

Dharia, S. P., Slane, A., Jian, M., Conner, M. G., Conley, A. J., & Parker, C. R. (2004) · Biology of Reproduction · doi:10.1095/biolreprod.103.026732 · Cited by 96 · see citing works

Role of growth factors in the developmental regulation of the human fetal adrenal cortex

Mesiano, S. A., & Jaffe, R. B. (1997) · Steroids · doi:10.1016/s0039-128x(96)00161-4 · Cited by 74 · see citing works

Human corticotropin-releasing hormone during pregnancy

Stalla, G. K., BOST, H., Stalk, J., Kaliebe, T., Dörr, H. G., Pfeiffer, D. G., von Werder, K., & Müller, O. A. (1989) · Gynecological Endocrinology · doi:10.3109/09513598909152447 · Cited by 72 · see citing works

Corticotropin Regulates Vascular Endothelial Growth Factor Expression in Human Fetal Adrenal Cortical Cells1

Shifren, J. L., Mesiano, S. A., Taylor, R. N., Ferrara, N., & Jaffe, R. B. (1998) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.83.4.4730 · Cited by 67 · see citing works

Functional maturation of the primate fetal adrenal in vivo: I. Role of insulin-like growth factors (IGFs), IGF-I receptor, and IGF binding proteins in growth regulation

Coulter, C. L., Goldsmith, P. C., Mesiano, S. A., Voytek, C. C., Martin, M. C., Han, V. K. M., & Jaffe, R. B. (1996) · Endocrinology · doi:10.1210/endo.137.10.8828511 · Cited by 63 · see citing works

Immunohistochemical evaluation of the cellular localization and ontogeny of 3β-hydroxysteroid dehydrogenase/delta 5-4 isomerase in the human fetal adrenal gland

Parker, C. R., Faye-Petersen, O. M., Stanković, A. K., Mason, J. I., & Grizzle, W. E. (1995) · Endocrine Research · doi:10.3109/07435809509030422 · Cited by 55 · see citing works

Corticotropin-releasing hormone stimulates steroidogenesis in cultured human adrenal cells

Parker, C. R., Stankovic, A. M., & Goland, R. (1999) · Molecular and Cellular Endocrinology · doi:10.1016/s0303-7207(99)00118-5 · Cited by 46 · see citing works

Corticotropin-Releasing Hormone Stimulates P450 17α-Hydroxylase/17,20-Lyase in Human Fetal Adrenal Cells via Protein Kinase C*

Chakravorty, A., Mesiano, S. A., & Jaffe, R. B. (1999) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.84.10.6053 · Cited by 41 · see citing works

Profiling the Steroidogenic Pathway in Human Fetal and Adult Adrenals

Rehman, K., Carr, B. R., & Rainey, W. E. (2003) · Journal of the Society for Gynecologic Investigation · doi:10.1016/s1071-5576(03)00118-7 · Cited by 35 · see citing works

Corticotrophin-releasing hormone-binding protein in human fetal plasma

Perkins, A. V., Wolfe, C. D. A., Eben, F., SOOTHILL, P. W., & Linton, E. A. (1995) · Journal of Endocrinology · doi:10.1677/joe.0.1460395 · Cited by 33 · see citing works

Regulation of Placental Corticotropin‐Releasing Hormone by Steroids

Karalis, K. P., & Majzoub, J. A. (1995) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1995.tb44709.x · Cited by 31 · see citing works

Cord plasma corticotropin-releasing factor-binding protein (CRF-BP) in term and preterm labour

Petraglia, F., Florio, P., Simoncini, T., Woods, R. J., Giuntini, A., Gremigni, R., Serra, G. B., Genazzani, A. R., & Lowry, P. J. (1997) · Placenta · doi:10.1016/s0143-4004(97)90082-5 · Cited by 29 · see citing works

Corticotropin Regulates Vascular Endothelial Growth Factor Expression in Human Fetal Adrenal Cortical Cells

Shifren, J. L. (1998) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.83.4.1342 · Cited by 29 · see citing works

Identification and isolation of corticotrophin-releasing hormone-positive cells from the human placenta

Perkins, A. V., & Linton, E. A. (1995) · Placenta · doi:10.1016/0143-4004(95)90111-6 · Cited by 22 · see citing works

Expression of 11?-hydroxylase (CYP11B1) and aldosterone synthase (CYP11B2) in the human fetal adrenal

Freije, W. A., Pezzi, V., ARICE, A., Carr, B. I., & Rainey, W. E. (1997) · Journal of the Society for Gynecologic Investigation · doi:10.1016/s1071-5576(97)00066-x · Cited by 17 · see citing works

Corticotropin-Releasing Hormone Stimulates P450 17 -Hydroxylase/17,20-Lyase in Human Fetal Adrenal Cells via Protein Kinase C

Chakravorty, A. (1999) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.84.10.3732 · Cited by 15 · see citing works

Congenital Adrenal Hyperplasia—Current Insights in Pathophysiology, Diagnostics, and Management

Claahsen - van der Grinten, H. L., Speiser, P. W., Ahmed, S. F., Arlt, W., Auchus, R. J., Falhammar, H., Flück, C. E., Guasti, L., Huebner, A., Kortmann, B. B. M., et al. (2022) · Endocrine Reviews · doi:10.1210/endrev/bnab016 · Cited by 556 · see citing works

Development and function of the human fetal adrenal cortex: a key component in the feto-placental unit

Ishimoto, H., & Jaffe, R. B. (2011) · Endocrine Reviews · doi:10.1210/er.2010-0001 · Cited by 379 · see citing works

The Molecular Mechanisms Underlying the Regulation of the Biological Activity of Corticotropin-Releasing Hormone Receptors: Implications for Physiology and Pathophysiology

Hillhouse, E. W., & Grammatopoulos, D. K. (2006) · Endocrine Reviews · doi:10.1210/er.2005-0034 · Cited by 353 · see citing works

Maternal corticosteroid use and orofacial clefts

Carmichael, S. L., Shaw, G. M., Ma, C., Werler, M. M., Rasmussen, S. A., & Lammer, E. J. (2007) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2007.05.046 · Cited by 301 · see citing works

Transcriptional regulation of steroidogenic genes: StARD1, CYP11A1 and HSD3B

LaVoie, H. A., & King, S. R. (2009) · Experimental Biology and Medicine · doi:10.3181/0903-mr-97 · Cited by 261 · see citing works

New insights into the role of perinatal HPA-axis dysregulation in postpartum depression

Glynn, L. M., Davis, E. P., & Sandman, C. A. (2013) · Neuropeptides · doi:10.1016/j.npep.2013.10.007 · Cited by 268 · see citing works

Development of adrenal cortex zonation

Xing, Y., Lerario, A. M., Rainey, W., & Hammer, G. D. (2015) · Endocrinology and Metabolism Clinics of North America · doi:10.1016/j.ecl.2015.02.001 · Cited by 174 · see citing works

Developmental origins of the human hypothalamic-pituitary-adrenal axis

Howland, M. A., Sandman, C. A., & Glynn, L. M. (2017) · Expert Review of Endocrinology & Metabolism · doi:10.1080/17446651.2017.1356222 · Cited by 171 · see citing works

Endocrinology of human parturition

Vannuccini, S., Bocchi, C., Severi, F. M., Challis, J. R., & Petraglia, F. (2016) · Annales d'Endocrinologie · doi:10.1016/j.ando.2016.04.025 · Cited by 173 · see citing works

Type 5 17β-hydroxysteroid dehydrogenase (AKR1C3) contributes to testosterone production in the adrenal reticularis

Nakamura, Y., Hornsby, P. J., Casson, P., Morimoto, R., Satoh, F., Xing, Y., Kennedy, M. R., Sasano, H., & Rainey, W. E. (2009) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2008-2374 · Cited by 129 · see citing works

Early Onset Pre-Eclampsia Is Associated with Altered DNA Methylation of Cortisol-Signalling and Steroidogenic Genes in the Placenta

Hogg, K., Blair, J. D., McFadden, D. E., von Dadelszen, P., & Robinson, W. P. (2013) · PLoS ONE · doi:10.1371/journal.pone.0062969 · Cited by 113 · see citing works

Adrenal Androgens and Androgen Precursors-Definition, Synthesis, Regulation and Physiologic Actions

Turcu, A., Smith, J. M., Auchus, R., & Rainey, W. E. (2014) · Comprehensive physiology · doi:10.1002/cphy.c140006 · Cited by 113 · see citing works

Steroid metabolome in plasma from the umbilical artery, umbilical vein, maternal cubital vein and in amniotic fluid in normal and preterm labor

Hill, M., Pařı́zek, A., Kancheva, R. L., Dušková, M., Velíková, M., Kříž, L., Klímková, M., Pašková, A., Žižka, Z., Matucha, P., et al. (2009) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2009.10.012 · Cited by 102 · see citing works

Neurobehavioral risk is associated with gestational exposure to stress hormones

Sandman, C. A., & Davis, E. P. (2012) · Expert Review of Endocrinology & Metabolism · doi:10.1586/eem.12.33 · Cited by 90 · see citing works

The Human Fetal Adrenal Gland, Corticotropin-Releasing Hormone, and Parturition

Beshay, V. E., Carr, B. R., & Rainey, W. E. (2007) · Seminars in Reproductive Medicine · doi:10.1055/s-2006-956772 · Cited by 88 · see citing works

Corticotropin-Releasing Hormone (CRH) and Urocortin Act through Type 1 CRH Receptors to Stimulate Dehydroepiandrosterone Sulfate Production in Human Fetal Adrenal Cells

Sirianni, R., Mayhew, B. A., Carr, B. R., Parker, C. R., & Rainey, W. E. (2005) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2005-0680 · Cited by 84 · see citing works

Steroid metabolome in fetal and maternal body fluids in human late pregnancy

Hill, M., Pařı́zek, A., Cibula, D., Kancheva, R. L., Jirasek, J. E., Jirkovská, M., Velíková, M., Kubátová, J., Klímková, M., Pašková, A., et al. (2010) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2010.05.007 · Cited by 75 · see citing works

Functions of corticotropin‐releasing hormone in anthropoid primates: From brain to placenta

Power, M. L., & Schulkin, J. A. (2006) · American Journal of Human Biology · doi:10.1002/ajhb.20521 · Cited by 69 · see citing works

The corticotropin-releasing factor (CRF) family of peptides as local modulators of adrenal function

Tsatsanis, C., Dermitzaki, E., Venihaki, M., Chatzaki, Ε., MINAS, V., Gravanis, A., & Margioris, A. N. (2007) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-007-6555-7 · Cited by 63 · see citing works

Pediatric Adrenal Insufficiency: Diagnosis, Management, and New Therapies

Bowden, S. A., & Henry, R. K. (2018) · International Journal of Pediatrics · doi:10.1155/2018/1739831 · Cited by 63 · see citing works

Regulation of progesterone signaling during pregnancy: Implications for the use of progestins for the prevention of preterm birth

Byrns, M. C. (2013) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2013.01.015 · Cited by 55 · see citing works

Transcriptional Regulation of Adrenocortical Steroidogenic Gene Expression

Sewer, M. B., Dammer, E. B., & Jagarlapudi, S. (2007) · Drug Metabolism Reviews · doi:10.1080/03602530701498828 · Cited by 55 · see citing works

The role of CRH receptors and their agonists in myometrial contractility and quiescence during pregnancy and labour

Grammatopoulos, D. K. (2006) · Frontiers in bioscience · doi:10.2741/2082 · Cited by 54 · see citing works

Adrenal disorders in pregnancy

Monticone, S., Auchus, R. J., & Rainey, W. E. (2012) · Nature Reviews Endocrinology · doi:10.1038/nrendo.2012.155 · Cited by 53 · see citing works

Evolutionary Significance of the Neuroendocrine Stress Axis on Vertebrate Immunity and the Influence of the Microbiome on Early-Life Stress Regulation and Health Outcomes

Ortega, V. A., Mercer, E. M., Giesbrecht, G. F., & Arrieta, M. (2021) · Frontiers in Microbiology · doi:10.3389/fmicb.2021.634539 · Cited by 51 · see citing works

Changes in Placental CRH, Urocortins, and CRH-Receptor mRNA Expression Associated with Preterm Delivery and Chorioamnionitis

Torricelli, M., Novembri, R., Bloise, E., Bonis, M. D., Challis, J. R. G., & Petraglia, F. (2010) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2010-1740 · Cited by 50 · see citing works

Corticotropin-releasing hormone inhibits progesterone production in cultured human placental trophoblasts

Yang, R., You, X., Tang, X., Gao, L., & Ni, X. (2006) · Journal of Molecular Endocrinology · doi:10.1677/jme.1.02119 · Cited by 49 · see citing works

Urocortin 1, Urocortin 3/Stresscopin, and Corticotropin-Releasing Factor Receptors in Human Adrenal and Its Disorders

Fukuda, T., Takahashi, K., Suzuki, T., Saruta, M., Watanabe, M., Nakata, T., & Sasano, H. (2005) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2005-0090 · Cited by 47 · see citing works

Corticotropin-Releasing Hormone Stimulates Estrogen Biosynthesis in Cultured Human Placental Trophoblasts1

You, X., Yang, R., Tang, X., Gao, L., & Ni, X. (2006) · Biology of Reproduction · doi:10.1095/biolreprod.105.049361 · Cited by 46 · see citing works

Neuroendocrinology of pregnancy and parturition

Voltolini, C., & Petraglia, F. (2014) · Handbook of clinical neurology · doi:10.1016/b978-0-444-59602-4.00002-2 · Cited by 46 · see citing works

Preterm Birth and Corticotrophin-Releasing Hormone as a Placental Clock

Herrera, C. L., Maiti, K., & Smith, R. (2022) · Endocrinology · doi:10.1210/endocr/bqac206 · Cited by 43 · see citing works

Low Levels of Corticotropin-Releasing Hormone during Early Pregnancy Are Associated with Precocious Maturation of the Human Fetus

Class, Q. A., Buß, C., Davis, E. P., Gierczak, M., Pattillo, C., Chicz-DeMet, A., & Sandman, C. A. (2008) · Developmental Neuroscience · doi:10.1159/000191213 · Cited by 43 · see citing works

Transmission of the adverse consequences of childhood maltreatment across generations: Focus on gestational biology

Moog, N. K., Heim, C. C., Entringer, S., Simhan, H. N., Wadhwa, P. D., & Buß, C. (2022) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2022.173372 · Cited by 43 · see citing works

The hormonal control of parturition

Hamburg‐Shields, E., & Mesiano, S. A. (2024) · Physiological Reviews · doi:10.1152/physrev.00019.2023 · Cited by 43 · see citing works

Maternal exposure to childhood traumatic events, but not multi-domain psychosocial stressors, predict placental corticotrophin releasing hormone across pregnancy

Steine, I. M., LeWinn, K. Z., Lisha, N. E., Tylavsky, F. A., Smith, R., Bowman, M. E., Sathyanarayana, S., Karr, C. J., Smith, A. K., Kobor, M. S., et al. (2020) · Social Science & Medicine · doi:10.1016/j.socscimed.2020.113461 · Cited by 43 · see citing works

The Regulation of Adrenocorticotrophic Hormone Receptor by Corticotropin-Releasing Hormone in Human Fetal Adrenal Definitive/Transitional Zone Cells

Rehman, K. S., Sirianni, R., Parker, C. R., Rainey, W. E., & Carr, B. R. (2007) · Reproductive Sciences · doi:10.1177/1933719107307908 · Cited by 36 · see citing works

Neurobehavioral Consequences of Fetal Exposure to Gestational Stress

Sandman, C. A., Glynn, L. M., & Davis, E. P. (2016) · Springer eBooks · doi:10.1007/978-3-319-22023-9_13 · Cited by 37 · see citing works

The Prenatal Hormone Milieu in Autism Spectrum Disorder

Worsham, W., Dalton, S., & Bilder, D. A. (2021) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2021.655438 · Cited by 29 · see citing works

Predictive factors for neurocognitive function and Quality of Life after surgical treatment for Cushing's disease and acromegaly.

Psaras, T., Milian, M., Hattermann, V., Will, B. E., Tatagiba, M. S., & Honegger, J. B. (2011) · PubMed · doi:10.3275/7333 · Cited by 31 · see citing works

Metastin Stimulates Aldosterone Synthesis in Human Adrenal Cells

Nakamura, Y., Aoki, S., Xing, Y., Sasano, H., & Rainey, W. E. (2007) · Reproductive Sciences · doi:10.1177/1933719107307823 · Cited by 31 · see citing works

The human adrenal cortex: growth control and disorders

Lotfi, C. F. P., Kremer, J. L., Passaia, B. D. S., & Cavalcante, I. P. (2018) · Clinics · doi:10.6061/clinics/2018/e473s · Cited by 30 · see citing works

Corticotropin-Releasing Hormone Receptor Expression on Normal and Tumorous Human Adrenocortical Cells

Willenberg, H. S., Haase, M., Papewalis, C., Schott, M., Scherbaum, W. A., & Bornstein, S. R. (2005) · Neuroendocrinology · doi:10.1159/000093126 · Cited by 30 · see citing works

A Comprehensive Evaluation of Steroid Metabolism in Women with Intrahepatic Cholestasis of Pregnancy

Pařı́zek, A., Hill, M., Dušková, M., Vı́tek, L., Velíková, M., Kancheva, R. L., Šimják, P., Koucký, M., Kokrdová, Z., Adamcová, K., et al. (2016) · PLoS ONE · doi:10.1371/journal.pone.0159203 · Cited by 27 · see citing works

Skeletal receptors for steroid‐family regulating glycoprotein hormones

Blair, H. C., Robinson, L., Sun, L., Isales, C., Davies, T. F., & Zaidi, M. (2011) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2011.06287.x · Cited by 29 · see citing works

Primary Cultures and Cell Lines for In Vitro Modeling of the Human Adrenal Cortex

Nanba, K., Blinder, A., & Rainey, W. E. (2021) · The Tohoku Journal of Experimental Medicine · doi:10.1620/tjem.253.217 · Cited by 25 · see citing works

Adrenal Androgens and Androgen Precursors—Definition, Synthesis, Regulation and Physiologic Actions

Turcu, A. F., Smith, J. M., Auchus, R. J., & Rainey, W. E. (2014) · Comprehensive physiology · doi:10.1002/j.2040-4603.2014.tb00590.x · Cited by 26 · see citing works

The AP-1 family member FOS blocks transcriptional activity of the nuclear receptor steroidogenic factor 1

Sirianni, R., Nogueira, E. F., Bassett, M. H., Carr, B. R., Suzuki, T., Pezzi, V., Andò, S., & Rainey, W. E. (2010) · Journal of Cell Science · doi:10.1242/jcs.055806 · Cited by 25 · see citing works

Maternal Corticosteroid Use and Hypospadias

Carmichael, S. L., Ma, C., Werler, M. M., Olney, R. S., & Shaw, G. M. (2009) · The Journal of Pediatrics · doi:10.1016/j.jpeds.2009.01.039 · Cited by 25 · see citing works

Increases in maternal depressive symptoms during pregnancy and infant cortisol reactivity: Mediation by placental corticotropin-releasing hormone

Rinne, G. R., Somers, J. A., Ramos, I. F., Ross, K. M., Coussons‐Read, M. E., & Schetter, C. D. (2022) · Development and Psychopathology · doi:10.1017/s0954579422000621 · Cited by 26 · see citing works

Exploration of the Hypothalamic-Pituitary-Adrenal Axis to Improve Animal Welfare by Means of Genetic Selection: Lessons from the South African Merino

Hough, D., Swart, P., & Cloete, S. (2013) · Animals · doi:10.3390/ani3020442 · Cited by 25 · see citing works

A Long-Acting Neutralizing Monoclonal ACTH Antibody Blocks Corticosterone and Adrenal Gene Responses in Neonatal Rats

Gehrand, A. L., Phillips, J., Malott, K., & Raff, H. (2019) · Endocrinology · doi:10.1210/en.2019-00117 · Cited by 21 · see citing works

Expression and Role of the Corticotropin-Releasing Hormone/Urocortin-Receptor-Binding Protein System in the Primate Corpus Luteum during the Menstrual Cycle

Xu, J., Xu, F., Hennebold, J. D., Molskness, T. A., & Stouffer, R. L. (2007) · Endocrinology · doi:10.1210/en.2007-0541 · Cited by 22 · see citing works

Regulation of Estradiol and Progesterone Production by CRH-R1 and -R2 Is through Divergent Signaling Pathways in Cultured Human Placental Trophoblasts

Gao, L., Yi, T., Hu, T., Liu, W., Xu, C., Liu, J., You, X., Gu, H., & Ni, X. (2012) · Endocrinology · doi:10.1210/en.2012-1453 · Cited by 22 · see citing works

H295R expression of melanocortin 2 receptor accessory protein results in ACTH responsiveness

Nanba, K., Chen, A., Turcu, A. F., & Rainey, W. E. (2015) · Journal of Molecular Endocrinology · doi:10.1530/jme-15-0230 · Cited by 21 · see citing works

Genetics and Pathophysiology of Classic Congenital Adrenal Hyperplasia Due to 21-Hydroxylase Deficiency

Yang, M., & White, P. C. (2025) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/clinem/dgae535 · Cited by 20 · see citing works

Placental Endocrine Function and Hormone Action

Albrecht, E. D., & Pepe, G. J. (2014) · Elsevier eBooks · doi:10.1016/b978-0-12-397175-3.00040-5 · Cited by 20 · see citing works

Urocortin 2 Stimulates Estradiol Secretion From Cultured Human Placental Cells: An Effect Mediated by the Type 2 Corticotrophin-releasing Hormone (CRH) Receptor

Imperatore, A., Li, W., Petraglia, F., & Challis, J. R. G. (2009) · Reproductive Sciences · doi:10.1177/1933719109332830 · Cited by 18 · see citing works

Involvement of CRH and hCG in the induction of aromatase by cortisol in human placental syncytiotrophoblasts

Wang, W. S., Liu, C., Li, W. J., Zhu, P., Li, J. N., & Sun, K. (2014) · Placenta · doi:10.1016/j.placenta.2013.10.018 · Cited by 25 · see citing works

CRH Acts on CRH-R1 and -R2 to Differentially Modulate the Expression of Large-Conductance Calcium-Activated Potassium Channels in Human Pregnant Myometrium

Xu, C., Gao, L., You, X., Dai, L., Li, Y., Gu, H., Slater, D. M., Olson, D. M., & Ni, X. (2011) · Endocrinology · doi:10.1210/en.2011-0262 · Cited by 17 · see citing works

Expression of urocortin 3/stresscopin in human adrenal glands and adrenal tumors

Takahashi, K., Totsune, K., Saruta, M., Fukuda, T., SUZUKI, T. A., Hirose, T., Imai, Y., Sasano, H., & Murakami, O. (2005) · Peptides · doi:10.1016/j.peptides.2005.06.017 · Cited by 17 · see citing works

Human placenta releases extracellular vesicles carrying corticotrophin releasing hormone mRNA into the maternal blood

Paul, N., Maiti, K., Sultana, Z., Fisher, J. J., Zhang, H., Cole, N., Morgan, T. K., & Smith, R. (2024) · Placenta · doi:10.1016/j.placenta.2024.01.004 · Cited by 16 · see citing works

An epigenetic pathway approach to investigating associations between prenatal exposure to maternal mood disorder and newborn neurobehavior

Conradt, E. D., Adkins, D. E., Crowell, S. E., Monk, C. E., & Kobor, M. S. (2018) · Development and Psychopathology · doi:10.1017/s0954579418000688 · Cited by 16 · see citing works

Circadian Rhythm Dysfunction in Neurodegenerative Diseases: A Bidirectional Perspective and Therapeutic Potential

Namgyal, D., & Lim, C. (2025) · Nature and Science of Sleep · doi:10.2147/nss.s561326 · Cited by 14 · see citing works

Neuroactive steroid exposure impacts neurodevelopment: Comparison of human and rodent placental contribution

Vacher, C., Tsompanidis, A., Firestein, M. R., & Penn, A. A. (2025) · Journal of Neuroendocrinology · doi:10.1111/jne.13489 · Cited by 12 · see citing works

100th anniversary of the discovery of the human adrenal fetal zone by Stella Starkel and Lesław Węgrzynowski: how far have we come?

Malendowicz, L. K. (2011) · Folia Histochemica et Cytobiologica · doi:10.2478/v10042-010-0062-7 · Cited by 10 · see citing works

Placental urocortin-2 and -3: Endocrine or Paracrine Functioning During Healthy Pregnancy?

Pepels, P. P. L. M., Spaanderman, M. E. A., Hermus, A. R. M. M., Lotgering, F. K., & Sweep, F. C. G. J. (2010) · Placenta · doi:10.1016/j.placenta.2010.03.012 · Cited by 10 · see citing works

Orexins/hypocretins increase the promoter activity of selective steroidogenic enzymes

Kagerer, S. M., Eichholz, C., & Jöhren, O. (2011) · Peptides · doi:10.1016/j.peptides.2011.01.004 · Cited by 8 · see citing works

Pregestational Prediabetes Induces Maternal Hypothalamic–Pituitary–Adrenal (HPA) Axis Dysregulation and Results in Adverse Foetal Outcomes

Ngema, M., Xulu, N. D., Khathi, A., & Ngubane, P. S. (2024) · International Journal of Molecular Sciences · doi:10.29086/10413/24637 · Cited by 8 · see citing works

Repeating ACTH Stimulation Test Is Necessary to Diagnose ACTH Deficiency in Neonatal Hypopituitarism With Initial False Negative Result

Coshway, L., Indyk, J. A., & Bowden, S. A. (2014) · Global Pediatric Health · doi:10.1177/2333794x14563385 · Cited by 7 · see citing works

Fetal and Neonatal Adrenocortical Physiology

Watterberg, K. L. (2011) · Elsevier eBooks · doi:10.1016/b978-1-4160-3479-7.10181-8 · Cited by 7 · see citing works

The Placental Steroid Hypothesis of Human Brain Evolution

Tsompanidis, A., Burton, G. J., Baron‐Cohen, S., & Dunbar, R. (2025) · Evolutionary Anthropology Issues News and Reviews · doi:10.1002/evan.70003 · Cited by 4 · see citing works

POMC-specific knockdown of MeCP2 leads to adverse phenotypes in mice chronically exposed to high fat diet

Frayre, P., Ponce-Rubio, K., Frayre, J., Medrano, J., & Na, E. S. (2023) · Behavioural Brain Research · doi:10.1016/j.bbr.2024.114863 · Cited by 5 · see citing works

Simple ultrasound evaluation of fetal adrenal glands as a marker of imminent preterm birth: a preliminary report

Gábor, M., Kunochová, I., Krizko, M., Feriancova, M. A., & Ferianec, V. (2021) · Bratislavské lekárske listy/Bratislava medical journal · doi:10.4149/bll_2021_115 · Cited by 5 · see citing works

Fetal and Neonatal Adrenocortical Physiology

Watterberg, K. L., & Muglia, L. J. (2016) · Elsevier eBooks · doi:10.1016/b978-0-323-35214-7.00147-5 · Cited by 5 · see citing works

Co-culture of H295R Adrenocortical Carcinoma and BeWo Choriocarcinoma Cells to Study Feto-placental Interactions: Focus on Estrogen Biosynthesis

Thibeault, A.-A. H., Sanderson, J. T., & Vaillancourt, C. (2017) · Methods in molecular biology · doi:10.1007/978-1-4939-7498-6_23 · Cited by 5 · see citing works

Placental Steroid Hormones in Preeclampsia: Multilayered Regulation of Endocrine Pathogenesis

Yang, Y. S., Zhang, S., Fang, X., Shao, T., Shao, X., & Wang, Y. (2025) · Endocrine Reviews · doi:10.1210/endrev/bnaf039 · Cited by 4 · see citing works

Current Screening Strategies for the Diagnosis of Adrenal Insufficiency in Children

Bowden, S. A. (2023) · Pediatric Health Medicine and Therapeutics · doi:10.2147/phmt.s334576 · Cited by 4 · see citing works

The role of corticoliberin concentration levels and placental CRH receptors 1 and 2 in the prolongation of pregnancy.

Kawka‐Paciorkowska, K., & Bręborowicz, G. H. (2022) · Gynecological Endocrinology · doi:10.1080/09513590.2022.2068521 · Cited by 4 · see citing works

The Pituitary‐Bone Connection

Zaidi, M., Yuen, T., Sun, L., Davies, T. F., Zallone, A. Z., & Blair, H. C. (2013) · Primer on the metabolic bone diseases and disorders of mineral metabolism · doi:10.1002/9781118453926.ch116 · Cited by 4 · see citing works

Factors of Fetal Origin in the Regulation of Labor Initiation and Preterm Birth

Ding, L., & Gao, L. (2023) · Maternal-Fetal Medicine · doi:10.1097/fm9.0000000000000200 · Cited by 3 · see citing works

A Specific CRH Antagonist Attenuates ACTH-Stimulated Cortisol Secretion in Ovine Adrenocortical Cells

Valego, N. K., & Rose, J. C. (2010) · Reproductive Sciences · doi:10.1177/1933719110361959 · Cited by 3 · see citing works

Materials and device architectures for cortisol detection: Mechanisms, measurement technologies, and clinical implications

Garg, M., Gulfishan, S., Mazhari, B. B. Z., Alam, M. W., Sirohi, A., Mathew, S., & Varghese, A. (2026) · Biochimie · doi:10.1016/j.biochi.2026.01.015 · Cited by 2 · see citing works

Pituitary Hormone-Driven Mechanism for Skeletal Loss

Yuen, T., Sun, L., Abu‐Amer, W., Liu, P., Davies, T. F., Blair, H. C., New, M. I., Zallone, A. Z., & Zaidi, M. (2017) · Molecular and integrative toxicology · doi:10.1007/978-3-319-56192-9_10 · Cited by 2 · see citing works

Fetal Endocrinology

Katugampola, H., Gevers, E. F., & Dattani, M. (2019) · Wiley eBooks · doi:10.1002/9781119152712.ch3 · Cited by 2 · see citing works

Glucocorticoids in pregnancy: a master-switch for fetal maturation

Tan, Y., Stark, M. J., Clifton, V. L., Wiese, M. D., Morrison, J. L., & Gatford, K. L. (2026) · Endocrine Reviews · doi:10.1210/endrev/bnag015 · Cited by 1 · see citing works

Introduction to the 2018 Keith L. Parker Award Lecture, William E. Rainey, PhD

Auchus, R. J. (2018) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2018.12.017 · Cited by 1 · see citing works

DEVELOPMENT OF THE CORTICAL AND MEDULLARY CELLS OF ADRENAL GLAND IN THE LONG-TAILED MACAQUE (Macaca fascicularis) DURING PRE- AND POSTNATAL PERIOD

Cahyadi, D. D., Nurhidayat, N., Supratikno, S., Novelina, S., Nisa, C., & Setijanto, H. (2019) · Jurnal Kedokteran Hewan - Indonesian Journal of Veterinary Sciences · doi:10.21157/j.ked.hewan.v13i1.12044 · Cited by 1 · see citing works

Reduced CRHR-2 in placental tissues is associated with the high DNA methylation of CRHR-2 promoter in idiopathic preterm birth.

Li, L., Cui, W., Zhang, Y., & Wang, Y. (2017) · PubMed Central · Cited by 1 · see citing works

The Human Fetal Adrenal Gland—A Review of Its Function and Development

Chen, L. X., & Carr, B. R. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-801238-3.65373-4 · Cited by 1 · see citing works

Developmental Endocrinology

DiVall, S. A., & Merjaneh, L. (2023) · Avery's Diseases of the Newborn · doi:10.1016/b978-0-323-82823-9.00082-9 · Cited by 1 · see citing works

Elucidating the role of phosphorylation on trafficking of Menkes protein in AtT-20 wild type cells.

Rege, S. S. (2008) · ScholarWorks@BGSU (Bowling Green State University)

The Pituitary–Bone Axis in Health and Disease

Zaidi, M., Yuen, T., Abu-Amer, W., Liu, P., Davies, T., New, M., Blair, H., Zallone, A., Rosen, C., & Sun, L. (2018) · Primer on the metabolic bone diseases and disorders of mineral metabolism · doi:10.1002/9781119266594.ch133

Development of Adrenocorticotrophic Hormone Cells of Adenohypophysis–Adrenal Cortex Axis of Long-tailed Monkey (Macaca fascicularis) during Pre and Postnatal Period

Nurhidayat, N., Syarifah, I. K., Supratikno, S., & Wahyuni, S. (2008) · Jurnal Kedokteran Hewan - Indonesian Journal of Veterinary Sciences · doi:10.21157/j.ked.hewan.v2i2.9783

METAL CONTAMINATION OF THREE COMMERCIALLY FISH SPECIES COLLECTED FROM ACEH (INDONESIA) AND PENANG (MALAYSIA)

Sofia, S. (2009) · Jurnal Kedokteran Hewan - Indonesian Journal of Veterinary Sciences · doi:10.21157/j.ked.hewan.v3i2.9787

Embryology of the Adrenal Glands

Brookman-May, S. D. (2025) · Springer eBooks · doi:10.1007/978-3-031-55405-6_86

Adrenal Cortex and Medulla Physiology during Pregnancy, Labor, and Puerperium

St‐Jean, M., Bourdeau, I., & Lacroix, A. (2025) · Elsevier eBooks · doi:10.1016/b978-0-443-23940-3.00052-1

Rôle de la signalisation PKA dans la zonation de la glande surrénale : modèles génétiques murins et mécanismes post-traductionnels

Dumontet, T. (2017) · theses.fr (ABES) · doi:10.70675/7076b966z729fz4200z82dcz22235060a8bd

Organoid-like Functional Adrenal Gland Cortex Derived From Human Pluripotent Stem CellsPreprint

MCALPINE, J. N., James, C., Dalal, B., Thomas, K., Knight, T., & Zeltner, N. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.06.30.735632

The Regulation of Adrenocorticotrophic Hormone Receptor by Corticotropin-Releasing Hormone in Human Fetal Adrenal Definitive/Transitional Zone Cells

Rehman, K. S., Sirianni, R., Parker, C. R., Rainey, W. E., & Carr, B. R. (2007) · Reproductive Sciences · doi:10.1177/1933719107307908 · Cited by 36 · see citing works

Corticotropin-Releasing Hormone (CRH) and Urocortin Act through Type 1 CRH Receptors to Stimulate Dehydroepiandrosterone Sulfate Production in Human Fetal Adrenal Cells

Sirianni, R., Mayhew, B. A., Carr, B. R., Parker, C. R., & Rainey, W. E. (2005) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2005-0680 · Cited by 84 · see citing works

Corticotropin-Releasing Hormone Directly and Preferentially Stimulates Dehydroepiandrosterone Sulfate Secretion by Human Fetal Adrenal Cortical Cells

Smith, R., Mesiano, S. A., Chan, E., Brown, S. A., & Jaffe, R. B. (1998) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.83.8.5020 · Cited by 249 · see citing works

Corticotropin-releasing hormone stimulates steroidogenesis in cultured human adrenal cells

Parker, C. R., Stankovic, A. M., & Goland, R. (1999) · Molecular and Cellular Endocrinology · doi:10.1016/s0303-7207(99)00118-5 · Cited by 46 · see citing works

Corticotropin-Releasing Hormone Stimulates P450 17α-Hydroxylase/17,20-Lyase in Human Fetal Adrenal Cells via Protein Kinase C*

Chakravorty, A., Mesiano, S. A., & Jaffe, R. B. (1999) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.84.10.6053 · Cited by 41 · see citing works