Adrenal Androgens and Androgen Precursors-Definition, Synthesis, Regulation and Physiologic Actions

Abiraterone and Increased Survival in Metastatic Prostate Cancer

de Bono, J. S., Logothetis, C. J., Molina, A., Fizazi, K., North, S., Chu, L., Chi, K. N., Jones, R. J., Goodman, O. B., Saad, F., et al. (2011) · New England Journal of Medicine · doi:10.1056/nejmoa1014618 · Cited by 4,407 · see citing works

Abiraterone in Metastatic Prostate Cancer without Previous Chemotherapy

Ryan, C. J., Smith, M. R., de Bono, J. S., Molina, A., Logothetis, C. J., de Souza, P., Fizazi, K., Mainwaring, P., Piulats, J. M., Ng, S., et al. (2013) · New England Journal of Medicine · doi:10.1056/nejmoa1209096 · Cited by 2,796 · see citing works

The Prevalence and Features of the Polycystic Ovary Syndrome in an Unselected Population

Azziz, R., Woods, K. S., Reyna, R., Key, T. J., Knochenhauer, E. S., & Yıldız, B. O. (2004) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2003-032046 · Cited by 2,715 · see citing works

The Molecular Biology, Biochemistry, and Physiology of Human Steroidogenesis and Its Disorders

Miller, W. L., & Auchus, R. J. (2011) · Endocrine Reviews · doi:10.1210/er.2010-0013 · Cited by 2,458 · see citing works

Diagnosis and Treatment of Polycystic Ovary Syndrome: An Endocrine Society Clinical Practice Guideline

Legro, R. S., Arslanian, S. A., Ehrmann, D. A., Hoeger, K. M., Murad, M. H., Pasquali, R., & Welt, C. K. (2013) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2013-2350 · Cited by 1,919 · see citing works

Secondary sexual characteristics and menses in young girls seen in office practice: a study from the Pediatric Research in Office Settings network

Herman-Giddens, M. E., Slora, E. J., Wasserman, R. C., Bourdony, C. J., Bhapkar, M. V., Koch, G. G., & Hasemeier, C. M. (1997) · PEDIATRICS · doi:10.1542/peds.99.4.505 · Cited by 1,709 · see citing works

The P450 Superfamily: Update on New Sequences, Gene Mapping, Accession Numbers, Early Trivial Names of Enzymes, and Nomenclature

Nelson, D. R., Kamataki, T., Waxman, D. J., Guengerich, F. P., Estabrook, R. W., Feyereisen, R., Gonzalez, F. J., Coon, M. J., GUNSALUS, I. C., Gotoh, O., et al. (1993) · DNA and Cell Biology · doi:10.1089/dna.1993.12.1 · Cited by 1,637 · see citing works

Congenital Adrenal Hyperplasia

Speiser, P., & White, P. C. (1987) · New England Journal of Medicine · doi:10.1056/nejm198711263172211 · Cited by 1,409 · see citing works

Age changes and sex differences in serum dehydroepiandrosterone sulfate concentrations throughout adulthood

ORENTREICH, N., BRIND, J. L., RIZER, R. L., & VOGELMAN, J. H. (1984) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-59-3-551 · Cited by 1,349 · see citing works

Steroid 5α-Reductase Deficiency in Man: An Inherited Form of Male Pseudohermaphroditism

Imperato-McGinley, J., Guerrero, L., Gautier, T., & Peterson, R. E. (1974) · Science · doi:10.1126/science.186.4170.1213 · Cited by 1,258 · see citing works

Some properties of a detergent-solubilized NADPH-cytochrome c(cytochrome P-450) reductase purified by biospecific affinity chromatography.

Yasukochi, Y., & Masters, B. S. S. (1976) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)33166-6 · Cited by 1,180 · see citing works

The purification, cloning and expression of a novel luteinizing hormone-induced mitochondrial protein in MA-10 mouse Leydig tumor cells. Characterization of the steroidogenic acute regulatory protein (StAR)

Clark, B. J., Wells, J., King, S. R., & Stocco, D. M. (1994) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)46930-x · Cited by 1,168 · see citing works

Regulation of the acute production of steroids in steroidogenic cells

STOCCO, D. M., & CLARK, B. J. (1996) · Endocrine Reviews · doi:10.1210/edrv-17-3-221 · Cited by 1,057 · see citing works

Role of steroidogenic acute regulatory protein in adrenal and gonadal steroidogenesis

Lin, D., Sugawara, T., Strauss, J. F., Clark, B. J., Stocco, D. M., Saenger, P., Rogol, A., & Miller, W. L. (1995) · Science · doi:10.1126/science.7892608 · Cited by 1,030 · see citing works

The pathophysiology and genetics of congenital lipoid adrenal hyperplasia

Bose, H. S., Sugawara, T., Strauss, J. F., & Miller, W. L. (1996) · New England Journal of Medicine · doi:10.1056/nejm199612193352503 · Cited by 676 · see citing works

Human 3α-hydroxysteroid dehydrogenase isoforms (AKR1C1–AKR1C4) of the aldo–keto reductase superfamily: functional plasticity and tissue distribution reveals roles in the inactivation and formation of male and female sex hormones

PENNING, T. M., BURCZYNSKI, M. E., JEZ, J. M., HUNG, C.-F., LIN, H.-K., MA, H., MOORE, M., PALACKAL, N., & RATNAM, K. (2000) · Biochemical Journal · doi:10.1042/0264-6021:3510067 · Cited by 649 · see citing works

Human 3α-hydroxysteroid dehydrogenase isoforms (AKR1C1-AKR1C4) of the aldo-keto reductase superfamily: functional plasticity and tissue distribution reveals roles in the inactivation and formation of male and female sex hormones

PENNING, T. M., BURCZYNSKI, M. E., JEZ, J. M., HUNG, C.-F., LIN, H.-K., MA, H., MOORE, M., PALACKAL, N., & RATNAM, K. (2000) · Biochemical Journal · doi:10.1042/bj3510067 · Cited by 649 · see citing works

Regulation of the acute production of steroids in steroidogenic cells

Stocco, D. M. (1996) · Endocrine Reviews · doi:10.1210/er.17.3.221 · Cited by 635 · see citing works

Molecular biology of the 3β-hydroxysteroid dehydrogenase/Δ5-Δ4 –isomerase gene family

Simard, J., Ricketts, M.-L., Gingras, S., Soucy, P., Feltus, F. A., & Melner, M. H. (2005) · Endocrine Reviews · doi:10.1210/er.2002-0050 · Cited by 620 · see citing works

Insulin Stimulates Testosterone Biosynthesis by Human Thecal Cells from Women with Polycystic Ovary Syndrome by Activating Its Own Receptor and Using Inositolglycan Mediators as the Signal Transduction System¹

Nestler, J. E., Jakubowicz, D. J., Falcon de Vargas, A., Brik, C., Quintero, N., & Medina, F. (1998) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.83.6.4886 · Cited by 617 · see citing works

Enzymology of human cytosolic sulfotransferases

Falany, C. N. (1997) · The FASEB Journal · doi:10.1096/fasebj.11.4.9068609 · Cited by 604 · see citing works

Male pseudohermaphroditism caused by mutations of testicular 17β-hydroxysteroid dehydrogenase 3

Geissler, W. M., Davis, D. L., Wu, L., Bradshaw, K. D., Patel, S., Mendonca, B. B., Elliston, K. O., Wilson, J. D., Russell, D. W., & Andersson, S. (1994) · Nature Genetics · doi:10.1038/ng0594-34 · Cited by 570 · see citing works

17-Hydroxylation deficiency in man

Biglieri, E. G., Herron, M. A., & Brust, N. (1966) · Journal of Clinical Investigation · doi:10.1172/jci105499 · Cited by 561 · see citing works

Cytochrome b 5 Augments the 17,20-Lyase Activity of Human P450c17 without Direct Electron Transfer

Auchus, R. J., Lee, T. C., & Miller, W. L. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.6.3158 · Cited by 541 · see citing works

Structure and lipid transport mechanism of a StAR-related domain

Tsujishita (2000) · Nature Structural Biology · doi:10.1038/75192 · Cited by 535 · see citing works

Sulfonation and molecular action

Strott, C. A. (2002) · Endocrine Reviews · doi:10.1210/er.2001-0040 · Cited by 487 · see citing works

Premature Adrenarche - A Common Condition with Variable Presentation

Utriainen, P., Laakso, S. M., Liimatta, J., Jääskeläinen, J., & Voutilainen, R. (2015) · Hormone Research in Paediatrics · doi:10.1159/000369458 · Cited by 477 · see citing works

Targeted disruption of the mouse gene encoding steroidogenic acute regulatory protein provides insights into congenital lipoid adrenal hyperplasia

Caron, K. M., Soo, S.-C., Wetsel, W. C., Stocco, D. M., Clark, B. J., & Parker, K. L. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.21.11540 · Cited by 449 · see citing works

Cytochrome P450c17 (steroid 17 alpha-hydroxylase/17,20 lyase): cloning of human adrenal and testis cDNAs indicates the same gene is expressed in both tissues.

Chung, B. C., Picado-Leonard, J., Haniu, M., Bienkowski, M., Hall, P. F., Shively, J. E., & Miller, W. L. (1987) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.84.2.407 · Cited by 444 · see citing works

Ovarian and adrenal contribution to peripheral androgens during the menstrual cycle

ABRAHAM, G. E. (1974) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-39-2-340 · Cited by 436 · see citing works

Premature Adrenarche--Normal Variant or Forerunner of Adult Disease?

Ibáñez, L., DiMartino-Nardi, J., Potau, N., & Saenger, P. H. (2000) · Endocrine Reviews · doi:10.1210/edrv.21.6.0416 · Cited by 414 · see citing works

Sulfation and sulfotransferases 1: Sulfotransferase molecular biology: cDNAs and genes.

Weinshilboum, R. M., Otterness, D. M., Aksoy, I. A., Wood, T. C., Her, C., & Raftogianis, R. B. (1997) · PubMed · Cited by 408 · see citing works

17α-Hydroxylase/17,20 lyase deficiency: from clinical investigation to molecular definition

YANASE, T., SIMPSON, E. R., & WATERMAN, M. R. (1991) · Endocrine Reviews · doi:10.1210/edrv-12-1-91 · Cited by 390 · see citing works

Expression of Bovine 17α-Hydroxylase Cytochrome P-450 cDNA in Nonsteroidogenic (COS 1) Cells

Zuber, M. X., Simpson, E. R., & Waterman, M. R. (1986) · Science · doi:10.1126/science.3535074 · Cited by 388 · see citing works

Human steroidogenic acute regulatory protein: functional activity in COS-1 cells, tissue-specific expression, and mapping of the structural gene to 8p11.2 and a pseudogene to chromosome 13.

Sugawara, T., Holt, J. A., Driscoll, D., Strauss, J. F., Lin, D., Miller, W. L., Patterson, D., Clancy, K. P., Hart, I. M., & Clark, B. J. (1995) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.92.11.4778 · Cited by 382 · see citing works

Sulfotransferase molecular biology: cDNAs and genes

Weinshilboum, R. M., Otterness, D. M., Aksoy, I. A., Wood, T. C., Her, C., & Raftogianis, R. B. (1997) · The FASEB Journal · doi:10.1096/fasebj.11.1.9034160 · Cited by 369 · see citing works

Structure and Expression of a New Complementary DNA Encoding the almost Exclusive 3β-Hydroxysteroid Dehydrogenase/Δ ⁵ -Δ ⁴ -lsomerase in Human Adrenals and Gonads

Rhéaume, E., Lachance, Y., Zhao, H.-F., Breton, N., Dumont, M., Launoit, Y. D., Trudel, C., Luu-The, V., Simard, J., & Labrie, F. (1991) · Molecular Endocrinology · doi:10.1210/mend-5-8-1147 · Cited by 362 · see citing works

Human cholesterol side-chain cleavage enzyme, P450scc: cDNA cloning, assignment of the gene to chromosome 15, and expression in the placenta

Chung, B. C., Matteson, K. J., Voutilainen, R., Mohandas, T. K., & Miller, W. L. (1986) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.83.23.8962 · Cited by 354 · see citing works

The backdoor pathway to dihydrotestosterone

Auchus, R. J. (2004) · Trends in Endocrinology & Metabolism · doi:10.1016/j.tem.2004.09.004 · Cited by 347 · see citing works

Adrenarche: a survey of rodents, domestic animals and primates

CUTLER, G. B., GLENN, M., BUSH, M., HODGEN, G. D., GRAHAM, C. E., & LORIAUX, D. L. (1978) · Endocrinology · doi:10.1210/endo-103-6-2112 · Cited by 321 · see citing works

Full Length cDNA Structure and Deduced Amino Acid Sequence of Human β-Hydroxy-5-Ene Steroid Dehydrogenase

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The adrenogenital syndrome with deficiency of 3β-hydroxysteroid dehydrogenase

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Adrenarche—physiology, biochemistry and human disease

Auchus, R. J., & Rainey, W. E. (2004) · Clinical Endocrinology · doi:10.1046/j.1365-2265.2003.01858.x · Cited by 296 · see citing works

The Role of Cytochrome P450 17α-Hydroxylase and 3β-Hydroxysteroid Dehydrogenase in the Integration of Gonadal and Adrenal Steroidogenesis via the Δ5 and Δ4 Pathways of Steroidogenesis in Mammals

Conley, A. J., & Bird, I. M. (1997) · Biology of Reproduction · doi:10.1095/biolreprod56.4.789 · Cited by 295 · see citing works

Clinical and Biochemical Consequences of CYP17A1 Inhibition with Abiraterone Given with and without Exogenous Glucocorticoids in Castrate Men with Advanced Prostate Cancer

Attard, G., Reid, A. H. M., Auchus, R. J., Hughes, B. A., Mulick, A. R., Thompson, E., Oommen, N. B., Folkerd, E. J., Dowsett, M., Arlt, W., et al. (2011) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2011-2189 · Cited by 284 · see citing works

Dissecting human adrenal androgen production

Rainey, W. E., Carr, B. R., Sasano, H., Suzuki, T., & Mason, J. I. (2002) · Trends in Endocrinology and Metabolism · doi:10.1016/s1043-2760(02)00609-4 · Cited by 270 · see citing works

Adrenomedullary dysplasia and hypofunction in patients with classic 21-hydroxylase deficiency.

Merke, D. P., Chrousos, G. P., Eisenhofer, G., Weise, M., Keil, M. F., Rogol, A. D., Van Wyk, J. J., & Bornstein, S. R. (2000) · New England Journal of Medicine · doi:10.1056/nejm200011093431903 · Cited by 266 · see citing works

THE GENETICS, PATHOPHYSIOLOGX, AND MANAGEMENT OF HUMAN DEFICIENCIES OF P450c17

Auchus, R. J. (2001) · Endocrinology and Metabolism Clinics of North America · doi:10.1016/s0889-8529(08)70021-5 · Cited by 266 · see citing works

Characteristics of a Highly Labile Human Type 5 17β-Hydroxysteroid Dehydrogenase1

Dufort, I., Rheault, P., Huang, X.-F., Soucy, P., & Luu-The, V. (1999) · Endocrinology · doi:10.1210/endo.140.2.6531 · Cited by 255 · see citing works

Regulation of androgen production in cultured human thecal cells by insulin-like growth factor I and insulin

Bergh, C., Carlsson, B., Olsson, J., Selleskog, U., & Hillensjø, T. (1993) · Fertility and Sterility · doi:10.1016/s0015-0282(16)55675-1 · Cited by 253 · see citing works

The utilization of circulating dehydroisoandrosterone sulfate for estrogen synthesis during human pregnancy

Siiteri, P. K., & MacDonald, P. C. (1963) · Steroids · doi:10.1016/0039-128x(63)90044-8 · Cited by 252 · see citing works

MLN64 contains a domain with homology to the steroidogenic acute regulatory protein (StAR) that stimulates steroidogenesis

Watari, H., Arakane, F., Moog-Lutz, C., Kallen, C. B., Tomasetto, C., Gerton, G. L., Rio, M.-C., Baker, M. E., & Strauss, J. F. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.16.8462 · Cited by 247 · see citing works

Congenital adrenal hyperplasia due to point mutations in the type II 3β-hydroxysteroid dehydrogenase gene

Rhéaume, E., Simard, J., Morel, Y., Mebarki, F., Zachmann, M., Forest, M. G., New, M. I., & Labrie, F. (1992) · Nature Genetics · doi:10.1038/ng0792-239 · Cited by 235 · see citing works

Liquid chromatography-tandem mass spectrometry analysis of human adrenal vein 19-carbon steroids before and after ACTH stimulation

Rege, J., Nakamura, Y., Satoh, F., Morimoto, R., Kennedy, M. R., Layman, L. C., Honma, S., Sasano, H., & Rainey, W. E. (2013) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2012-2912 · Cited by 227 · see citing works

Two Prevalent <i>CYP17</i> Mutations and Genotype-Phenotype Correlations in 24 Brazilian Patients with 17-Hydroxylase Deficiency

Costa-Santos, M., Kater, C. E., & Auchus, R. J. (2004) · The Journal of Clinical Endocrinology &amp; Metabolism · doi:10.1210/jc.2003-031021 · Cited by 224 · see citing works

The role of cytochrome b5 in the biosynthesis of androgens by human P450c17

Katagiri, M., Kagawa, N., & Waterman, M. R. (1995) · Archives of Biochemistry and Biophysics · doi:10.1006/abbi.1995.1173 · Cited by 223 · see citing works

Androgen Resistance — The Clinical and Molecular Spectrum

Flier, J. S., Underhill, L. H., & Griffin, J. E. (1992) · New England Journal of Medicine · doi:10.1056/nejm199202273260906 · Cited by 220 · see citing works

Premature Adrenarche--Normal Variant or Forerunner of Adult Disease?

Ibáñez, L. (2000) · Endocrine Reviews · doi:10.1210/er.21.6.671 · Cited by 220 · see citing works

The zona reticularis is the site of biosynthesis of dehydroepiandrosterone and dehydroepiandrosterone sulfate in the adult human adrenal cortex resulting from its low expression of 3 beta-hydroxysteroid dehydrogenase.

Endoh, A., Kristiansen, S. B., Casson, P. R., Buster, J. E., & Hornsby, P. J. (1996) · The Journal of Clinical Endocrinology &amp; Metabolism · doi:10.1210/jcem.81.10.8855801 · Cited by 219 · see citing works

Mitochondrial processing of newly synthesized steroidogenic acute regulatory protein (StAR), but not total StAR, mediates cholesterol transfer to cytochrome P450 side chain cleavage enzyme in adrenal cells

Artemenko, I. P., Zhao, D., Hales, D. B., Hales, K. H., & Jefcoate, C. R. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m107815200 · Cited by 217 · see citing works

Transcriptional regulation of steroid hydroxylase genes by corticotropin

John, M. E., John, M. C., Boggaram, V, Simpson, E. R., & Waterman, M. R. (1986) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.83.13.4715 · Cited by 217 · see citing works

Human 3β-Hydroxysteroid Dehydrogenase/ δ5→4Isomerase from Placenta: Expression in Nonsteroidogenic Cells of a Protein that Catalyzes the Dehydrogenation/Isomerization of C21 and C19 Steroids*

LORENCE, M. C., MURRY, B. A., TRANT, J. M., & MASON, J. I. (1990) · Endocrinology · doi:10.1210/endo-126-5-2493 · Cited by 212 · see citing works

Bovine adrenocortical cytochrome P-450(17 alpha). Regulation of gene expression by ACTH and elucidation of primary sequence.

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Plasma Adrenal and Gonadal Sex Steroids in Human Pubertal Development

Ducharme, J.-R., Forest, M. G., PERETTI, E. D., Sempe, M., COLLU, R., & Bertrand, J. (1976) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-42-3-468 · Cited by 203 · see citing works

Characterization of human 3 beta-hydroxysteroid dehydrogenase/delta 5-delta 4-isomerase gene and its expression in mammalian cells

Lachance, Y., Luu-The, V, Labrie, C., Simard, J., Dumont, M., de Launoit, Y., Guérin, S., Leblanc, G., & Labrie, F. (1990) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)30528-8 · Cited by 201 · see citing works

Developmental changes in steroidogenic enzymes in human postnatal adrenal cortex: immunohistochemical studies

Suzuki, T., Sasano, H., Takeyama, J., Kaneko, C., Freije, W. A., Carr, B. R., & Rainey, W. E. (2000) · Clinical Endocrinology · doi:10.1046/j.1365-2265.2000.01144.x · Cited by 199 · see citing works

11β-Hydroxydihydrotestosterone and 11-ketodihydrotestosterone, novel C19 steroids with androgenic activity: A putative role in castration resistant prostate cancer?

Storbeck, K.-H., Bloem, L. M., Africander, D., Schloms, L., Swart, P., & Swart, A. C. (2013) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2013.07.006 · Cited by 198 · see citing works

Expression and Characterization of Recombinant Type 2 3α-Hydroxysteroid Dehydrogenase (HSD) from Human Prostate: Demonstration of Bifunctional 3α/17β-HSD Activity and Cellular Distribution

Lin, H.-K., Jez, J. M., Schlegel, B. P., Peehl, D. M., Pachter, J. A., & Penning, T. M. (1997) · Molecular Endocrinology · doi:10.1210/mend.11.13.0026 · Cited by 194 · see citing works

Androgen production and metabolism in normal and virilized women

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Increased activation of the alternative “backdoor” pathway in patients with 21-hydroxylase deficiency: evidence from urinary steroid hormone analysis

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Unconjugated Dehydroepiandrosterone Plasma Levels in Normal Subjects from Birth to Adolescence in Human: The Use of a Sensitive Radioimmunoassay1

PERETTI, E. D., & Forest, M. G. (1976) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-43-5-982 · Cited by 185 · see citing works

P450c17 Mutations R347H and R358Q Selectively Disrupt 17,20-Lyase Activity by Disrupting Interactions with P450 Oxidoreductase and Cytochrome b₅

Geller, D. H., Auchus, R. J., & Miller, W. L. (1999) · Molecular Endocrinology · doi:10.1210/mend.13.1.0219 · Cited by 183 · see citing works

Secretion of the adrenal androgen, dehydroepiandrosterone sulfate, during normal infancy, childhood, and adolescence, in sick infants, and in children with endocrinologic abnormalities

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The 17, 20-Lyase Activity of Cytochrome P450c17 from Human Fetal Testis Favors the Δ⁵Steroidogenic Pathway

Flück, C. E., Miller, W. L., & Auchus, R. J. (2003) · The Journal of Clinical Endocrinology &amp; Metabolism · doi:10.1210/jc.2003-030143 · Cited by 173 · see citing works

5α-Androstane-3α,17β-diol is formed in tammar wallaby pouch young testes by a pathway involving 5α-pregnane-3α,17α-diol-20-one as a key intermediate

Wilson, J. D., Auchus, R. J., Leihy, M. W., Guryev, O. L., Estabrook, R. W., Osborn, S. M., Shaw, G., & Renfree, M. B. (2003) · Endocrinology · doi:10.1210/en.2002-220721 · Cited by 172 · see citing works

Metabolic regulation of androgen production by human thecal cells in vitro

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The Prepuberal and Puberal Growth of the Adrenal (Adrenarche)

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Diagnosis, epidemiology, and genetics of the polycystic ovary syndrome

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Inactivating <i>PAPSS2</i> Mutations in a Patient with Premature Pubarche

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Assessment of steroidogenesis and steroidogenic enzyme functions

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Structural Characterization of Normal and Mutant Human Steroid 17α- Hydroxylase Genes: Molecular Basis of One Example of Combined 17α- Hydroxylase/17,20 Lyase Deficiency

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Cortisol production rate. II. Normal infants, children, and adults.

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On the Mechanism of Action of the Adrenocorticotrophic Hormone

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Pharmacogenetics of human cytosolic sulfotransferases

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Insulin-like growth factors enhance steroidogenic enzyme and corticotropin receptor messenger ribonucleic acid levels and corticotropin steroidogenic responsiveness in cultured human adrenocortical cells

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Adrenarche Results from Development of a 3 -Hydroxysteroid Dehydrogenase-Deficient Adrenal Reticularis

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Identification of a Functional Polymorphism of the Human Type 5 17β-Hydroxysteroid Dehydrogenase Gene Associated with Polycystic Ovary Syndrome

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A Novel Homozygous Mutation in<i>CYP11A1</i>Gene Is Associated with Late-Onset Adrenal Insufficiency and Hypospadias in a 46,XY Patient

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THE EFFECT OF TESTOSTERONE AND ALLIED COMPOUNDS ON THE MINERAL, NITROGEN, AND CARBOHYDRATE METABOLISM OF A GIRL WITH ADDISON'S DISEASE 12

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Medroxyprogesterone Acetate and Dexamethasone Are Competitive Inhibitors of Different Human Steroidogenic Enzymes

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Hirsutism and the Variable Response of the Pilosebaceous Unit to Androgen

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Proopiocortin-Related Peptide Plasma Levels throughout Prepuberty and Puberty*

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CONGENITAL ADRENAL HYPERPLASIA OWING TO 3β-HYDROXYSTEROID DEHYDROGENASE DEFICIENCY

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Human proopiomelanocortin (79–96), a proposed androgen stimulatory hormone, does not affect steroidogenesis in cultured human fetal adrenal cells

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METABOLISM OF DEHYDROEPIANDROSTERONE AND DEHYDROEPIANDROSTERONE SULPHATE BY THE HUMAN FOETUS AT MIDPREGNANCY

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Expression and roles of steroidogenic acute regulatory (StAR) protein in 'non-classical', extra-adrenal and extra-gonadal cells and tissues

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Effects of transforming growth factor-beta 1 on human adrenocortical fasciculata-reticularis cell differentiated functions

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11β-Hydroxyandrostenedione Returns to the Steroid Arena: Biosynthesis, Metabolism and Function

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Human proopiomelanocortin (79–96), a proposed cortical androgen stimulating hormone, does not affect steroidogenesis in cultured human adult adrenal cells

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Cortisol Stimulates Secretion of Dehydroepiandrosterone in Human Adrenocortical Cells Through Inhibition of 3βHSD2

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Steroid Inhibitory Effects upon Human Adrenal 3βHydroxysteroid Dehydrogenase Activity*

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A form of lipoidosis of the adrenal cortex in an infant

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Ovarian, adrenal, and peripheral testosterone levels in the polycystic ovary syndrome

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‘Exaggerated adrenarche’ in children presenting with premature adrenarche

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Urinary Steroid Excretion Patterns in Hirsutism. I. Use of Adrenal and Ovarian Suppression Tests in the Study of Hirsutism1

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Near-miss apparent SIDS from adrenal crisis

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Human Dehydroepiandrosterone Sulfotransferase Gene: Molecular Cloning and Structural Characterization

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