Cited by 350Diabetes and associated disordersCeliac Disease Research and ManagementAdrenal Hormones and Disorders

The DOI matches its Crossref record; 120 of the 120 references it cites were found in a registry or an index.

Type 1 diabetes associated autoimmunity: natural history, genetic associations and screening

Barker, Jennifer M.·2006·The Journal of Clinical Endocrinology & Metabolism

DOI 10.1210/jc.2005-1679

Open this paper in CoChat — free account

Abstract

CONTEXT: Type 1 diabetes (T1D) is associated with autoimmune thyroid disease (AIT), celiac disease (CD), Addison's disease (AD), and other autoimmune diseases. These diseases can occur together in defined syndromes with distinct pathophysiology and characteristics: autoimmune polyendocrine syndrome I, autoimmune polyendocrine syndrome II, and the immunodysregulation polyendocrinopathy enteropathy X-linked syndrome. EVIDENCE ACQUISITION: Review of the medical literature was performed with particular attention to the natural history, genetic factors, and syndromes associated with T1D, AIT, CD, and AD. EVIDENCE SYNTHESIS: Genetic risk for these diseases overlaps and includes genes within the major histocompatibility complex (MHC) such as the human leukocyte antigens (HLA) DR and DQ alleles and the MHC I-related gene A (MIC-A). Other genes outside of the MHC have been associated with these autoimmune diseases, including the gene encoding the lymphoid tyrosine phosphatase (PTPN22) and the cytotoxic T lymphocyte-associated antigen-4 (CTLA-4) gene. CONCLUSION: Genetic risk for T1D overlaps with AIT, CD, and AD. Disease risk is associated with organ-specific autoantibodies, which can be used to screen subjects with T1D.

Integrity signals

Registry

Crossref · 10.1210/jc.2005-1679

Cites

120 of 120 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Serum TSH, T 4 , and Thyroid Antibodies in the United States Population (1988 to 1994): National Health and Nutrition Examination Survey (NHANES III)
Hollowell, J. G., Staehling, N. W., Flanders, W. D., Hannon, W. H., Gunter, E. W., Spencer, C. A., & Braverman, L. E. (2002) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.87.2.489 · Cited by 4,279
The Colorado Thyroid Disease Prevalence Study
Canaris, G. J., Manowitz, N. R., Mayor, G., & Ridgway, E. C. (2000) · Archives of Internal Medicine · doi:10.1001/archinte.160.4.526 · Cited by 2,824
THE SPECTRUM OF THYROID DISEASE IN A COMMUNITY: THE WHICKHAM SURVEY
Tunbridge, W. M. G., Evered, D. C., Hall, R., Appleton, D. R., BREWIS, M., CLARK, F., Evans, J. G., Young, E. T., Bird, T., & Smith, P. (1977) · Clinical Endocrinology · doi:10.1111/j.1365-2265.1977.tb01340.x · Cited by 2,665
Projection of an Immunological Self Shadow Within the Thymus by the Aire Protein
Anderson, M. S., Venanzi, E. S., Klein, L., Chen, Z.-B., Berzins, S., Turley, S., von Boehmer, H., Bronson, R., Dierich, A., Benoist, C., et al. (2002) · Science · doi:10.1126/science.1075958 · Cited by 2,582
The incidence of thyroid disorders in the community: a twenty-year follow-up of the Whickham Survey
Vanderpump, M. P. J., Tunbrldge, W. M. G., French, J. M., Appleton, D., Bates, D., Clark, F., Evans, J. G., Hasan, D. M., Rodgers, H., Tunbridge, F., et al. (1995) · Clinical Endocrinology · doi:10.1111/j.1365-2265.1995.tb01894.x · Cited by 2,432
Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease
Ueda, H., Howson, J. M. M., Esposito, L., Heward, J., Snook, Chamberlain, G., Rainbow, D. B., Hunter, K. M. D., Smith, A. N., Di Genova, G., et al. (2003) · Nature · doi:10.1038/nature01621 · Cited by 2,175
Identification of tissue transglutaminase as the autoantigen of celiac disease
Dieterich, W., Ehnis, T., Bauer, M., Donner, P., Volta, U., Riecken, E. O., & Schuppan, D. (1997) · Nature Medicine · doi:10.1038/nm0797-797 · Cited by 2,021
Positional cloning of the APECED gene
Nagamine, K., Peterson, P., Scott, H. S., Kudoh, J., Minoshima, S., Heino, M., Krohn, K. J. E., Lalioti, M. D., Mullis, P. E., Antonarakis, S. E., et al. (1997) · Nature Genetics · doi:10.1038/ng1297-393 · Cited by 1,439
A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes
Bottini, N., Musumeci, L., Alonso, A., Rahmouni, S., Nika, K., Rostamkhani, M., MacMurray, J. P., Meloni, T., Lucarelli, P., Pellecchia, M., et al. (2004) · Nature Genetics · doi:10.1038/ng1323 · Cited by 1,419
Care of Children and Adolescents With Type 1 Diabetes
Silverstein, J., Klingensmith, G., Copeland, K., Plotnick, L., Kaufman, F., Laffel, L., Deeb, L., Grey, M., Anderson, B., Holzmeister, L. A., et al. (2005) · Diabetes Care · doi:10.2337/diacare.28.1.186 · Cited by 1,312
An autoimmune disease, APECED, caused by mutations in a novel gene featuring two PHD-type zinc-finger domains
Aaltonen, J., Björses, P., Perheentupa, J., Horelli‐Kuitunen, N., Palotie, A. V., Peltonen, L., Lee, Y. S., Francis, F., Henning, S., Thiel, C. S., et al. (1997) · Nature Genetics · doi:10.1038/ng1297-399 · Cited by 1,214
Clinical Variation of Autoimmune Polyendocrinopathy–Candidiasis–Ectodermal Dystrophy (APECED) in a Series of 68 Patients
Ahonen, P., Myllärniemi, S., Sipilä, I., & Perheentupa, J. (1990) · New England Journal of Medicine · doi:10.1056/nejm199006283222601 · Cited by 1,068
Prevalence of Celiac Disease among Children in Finland
Mäki, M., Mustalahti, K., Kokkonen, J., Kulmala, P., Haapalahti, M., Karttunen, T. J., Ilonen, J., Laurila, K., Dahlbom, I., Hansson, T., et al. (2003) · New England Journal of Medicine · doi:10.1056/nejmoa021687 · Cited by 955
JM2, encoding a fork head–related protein, is mutated in X-linked autoimmunity–allergic disregulation syndrome
Chatila, T. A., Blaeser, F., Ho, N. Y., Lederman, H. M., Voulgaropoulos, C., Helms, C., & Bowcock, A. M. (2000) · Journal of Clinical Investigation · doi:10.1172/jci11679 · Cited by 937
Prediction of type I diabetes in first-degree relatives using a combination of insulin, GAD, and ICA512bdc/IA-2 autoantibodies
Verge, C. F., Gianani, R., Kawasaki, E., Yu, L., Pietropaolo, M., Chase, H. P., Eisenbarth, G. S., & Jackson, R. A. (1996) · Diabetes · doi:10.2337/diab.45.7.926 · Cited by 827
A Direct Role for NKG2D/MICA Interaction in Villous Atrophy during Celiac Disease
Hüe, S., Mention, J., Monteiro, R. C., Zhang, S., Cellier, C., Schmitz, J., Verkarre, V., Fodil, N., Bahram, S., Cerf–Bensussan, N., et al. (2004) · Immunity · doi:10.1016/j.immuni.2004.06.018 · Cited by 758
Autoimmune Polyendocrine Syndromes
Eisenbarth, G. S., & Gottlieb, P. A. (2004) · New England Journal of Medicine · doi:10.1056/nejmra030158 · Cited by 669
Autoantibody appearance and risk for development of childhood diabetes in offspring of parents with type 1 diabetes: the 2-year analysis of the German BABYDIAB Study.
Ziegler, A., Hummel, M., Schenker, M., & Bonifacio, E. E. (1999) · Diabetes · doi:10.2337/diabetes.48.3.460 · Cited by 640
Autoantibodies to tissue transglutaminase as predictors of celiac disease
Dieterich, W., Laag, E., Schöpper, H., Volta, U., Ferguson, A., Gillett, H. R., Riecken, E. O., & Schuppan, D. (1998) · Gastroenterology · doi:10.1016/s0016-5085(98)70007-1 · Cited by 586
Replication of an Association Between the Lymphoid Tyrosine Phosphatase Locus (LYP/PTPN22) With Type 1 Diabetes, and Evidence for Its Role as a General Autoimmunity Locus
Smyth, D. J., Cooper, J. D., Collins, J. E., Heward, J. M., Franklyn, J. A., Howson, J. M. M., Vella, A. V., Nutland, S. L., Rance, H. E., Maier, L. M., et al. (2004) · Diabetes · doi:10.2337/diabetes.53.11.3020 · Cited by 507
CTLA-4 Gene Polymorphism at Position 49 in Exon 1 Reduces the Inhibitory Function of CTLA-4 and Contributes to the Pathogenesis of Graves’ Disease
Kouki, T., Sawai, Y., Gardine, C. A., Fisfalen, M. E., Alegre, M., & DeGroot, L. J. (2000) · The Journal of Immunology · doi:10.4049/jimmunol.165.11.6606 · Cited by 506
Aire deficient mice develop multiple features of APECED phenotype and show altered immune response
Ramsey, C. (2002) · Human Molecular Genetics · doi:10.1093/hmg/11.4.397 · Cited by 466
The Codon 620 Tryptophan Allele of the Lymphoid Tyrosine Phosphatase (LYP) Gene Is a Major Determinant of Graves’ Disease
Velaga, M., Wilson, V., Jennings, C., Owen, C. J., Herington, S. D., Donaldson, P. T., Ball, S. G., James, R. A., Quinton, R., Perros, P., et al. (2004) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2004-1108 · Cited by 464
Prediction of IDDM in the General Population: Strategies Based on Combinations of Autoantibody Markers
Bingley, P. J., Bonifacio, E. E., Williams, A. J. K., Genovese, S., Bottazzo, G. F., & Gale, E. A. (1997) · Diabetes · doi:10.2337/diab.46.11.1701 · Cited by 460
Frequency of Thyroid Dysfunction in Diabetic Patients: Value of Annual Screening
Perros, P., McCrimmon, R. J., Shaw, G., & Frier, B. M. (1995) · Diabetic Medicine · doi:10.1111/j.1464-5491.1995.tb00553.x · Cited by 441
Autoimmune Polyglandular Syndrome Type 1
Betterle, C., Greggio, N. A., & Volpato, M. (1998) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.83.4.4682 · Cited by 433
Does cryptic gluten sensitivity play a part in neurological illness?
Hadjivassiliou, M., Gibson, A. A. M., Davies-Jones, G. A. B., Lobo, A., Stephenson, T. J., & Milford-Ward, A. (1996) · The Lancet · doi:10.1016/s0140-6736(96)90540-1 · Cited by 406
An autosomal locus causing autoimmune disease: autoimmune polyglandular disease type I assigned to chromosome 21
Aaltonen, J., Björses, P., Sandkuijl, L. A., Perheentupa, J., & Peltonen, L. (1994) · Nature Genetics · doi:10.1038/ng0994-83 · Cited by 378
Combined Analysis of Autoantibodies Improves Prediction of IDDM in Islet Cell Antibody-Positive Relatives
Bingley, P. J., Christie, M. R., Bonifacio, E. E., Bonfanti, R., Shattock, M., Fonte, M.-T., Bottazzo, G.-F., & Gale, E. A. (1994) · Diabetes · doi:10.2337/diab.43.11.1304 · Cited by 377
Malignancy and mortality in people with coeliac disease: population based cohort study
West, J., Logan, R. F., Smith, C. J. P., Hubbard, R., & Card, T. R. (2004) · BMJ · doi:10.1136/bmj.38169.486701.7c · Cited by 366
Mutations in the AIRE Gene: Effects on Subcellular Location and Transactivation Function of the Autoimmune Polyendocrinopathy-Candidiasis–Ectodermal Dystrophy Protein
Björses, P., Halonen, M., Palvimo, J. J., Kolmer, M., Aaltonen, J., Ellonen, P., Perheentupa, J., Ulmanen, I., & Peltonen, L. (2000) · The American Journal of Human Genetics · doi:10.1086/302765 · Cited by 354
Analysis of HLA-DQ Genotypes and Susceptibility in Insulin-Dependent Diabetes Mellitus
Baisch, J. M., Weeks, T., Giles, R. C., Hoover, M. L., Šťastný, P., & Capra, J. D. (1990) · New England Journal of Medicine · doi:10.1056/nejm199006283222602 · Cited by 329
Risk of Non-Hodgkin Lymphoma in Celiac Disease
Catassi, C. (2002) · JAMA · doi:10.1001/jama.287.11.1413 · Cited by 327
Association of a functional single‐nucleotide polymorphism of PTPN22 , encoding lymphoid protein phosphatase, with rheumatoid arthritis and systemic lupus erythematosus
Orozco, G., Sánchez, E., González-Gay, M. Á., López‐Nevot, M. Á., Torres, B., Cáliz, R., Ortego‐Centeno, N., Jiménez-Alonso, J. F., Pascual‐Salcedo, D., Balsa, A., et al. (2005) · Arthritis & Rheumatism · doi:10.1002/art.20771 · Cited by 312
Thyroid Autoimmunity in Children and Adolescents With Type 1 Diabetes
Kordonouri, O., Klinghammer, A., Lang, E. B., Grüters‐Kieslich, A., Grabert, M., Holl, R. W., & On behalf of the DPV-Initiative of the German Working Group for Pediatric Diabetology (2002) · Diabetes Care · doi:10.2337/diacare.25.8.1346 · Cited by 311
Islet cell antigen 512 is a diabetes-specific islet autoantigen related to protein tyrosine phosphatases.
Rabin, D. U., Pleasic, S. M., Shapiro, J., Yoo-Warren, H., Oles, J., Hicks, J. M., Goldstein, D. E., & Rae, P. M. M. (1994) · The Journal of Immunology · doi:10.4049/jimmunol.152.6.3183 · Cited by 305
Malignant lymphomas in coeliac disease: evidence of increased risks for lymphoma types other than enteropathy-type T cell lymphoma
Smedby, K. E., Åkerman, M., Hildebrand, H., Glimelius, B., Ekbom, A., & Askling, J. (2004) · Gut · doi:10.1136/gut.2003.032094 · Cited by 291
Occurrence of Celiac Disease After Onset of Type 1 Diabetes: A 6-Year Prospective Longitudinal Study
Barera, G., Bonfanti, R., Viscardi, M., Bazzigaluppi, E., Calori, G., Meschi, F., Bianchi, C., & Chiumello, G. (2002) · PEDIATRICS · doi:10.1542/peds.109.5.833 · Cited by 273
One Third of HLA DQ2 Homozygous Patients with Type 1 Diabetes Express Celiac Disease-Associated Transglutaminase Autoantibodies
Bao, F., Yu, L., Babu, S. R., Wang, T., Hoffenberg, E. J., Rewers, M., & Eisenbarth, G. S. (1999) · Journal of Autoimmunity · doi:10.1006/jaut.1999.0303 · Cited by 242
Absolute Risk of Childhood-Onset Type 1 Diabetes Defined by Human Leukocyte Antigen Class II Genotype: A Population-Based Study in the United Kingdom
Lambert, A. P., Gillespie, K. M., Thomson, G. J., Cordell, H. J., Todd, J. A., Gale, E. A., & Bingley, P. J. (2004) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2003-032084 · Cited by 241
Neurologic presentation of celiac disease
Bushara, K. O. (2005) · Gastroenterology · doi:10.1053/j.gastro.2005.02.018 · Cited by 241
APS-I/APECED: the clinical disease and therapy
Perheentupa, J. (2002) · Endocrinology and Metabolism Clinics of North America · doi:10.1016/s0889-8529(01)00013-5 · Cited by 233
ISLET-CELL ANTIBODIES IN JUVENILE DIABETES MELLITUS OF RECENT ONSET
Lendrum, R., Walker, G., & Gamble, D. R. (1975) · The Lancet · doi:10.1016/s0140-6736(75)91683-9 · Cited by 222
High prevalence and increasing incidence of Addison's disease in western Norway
Løvås, K., & Husebye, E. S. (2002) · Clinical Endocrinology · doi:10.1046/j.1365-2265.2002.t01-1-01552.x · Cited by 221
Antiislet autoantibodies usually develop sequentially rather than simultaneously
Yu, L., Rewers, M., Gianani, R., Kawasaki, E., Zhang, Y., Verge, C. F., Chase, P., KLINGENSMITH, G. J., Erlich, H., Norris, J. M., et al. (1996) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.81.12.8954025 · Cited by 217
The cytotoxic T lymphocyte antigen-4 is a major Graves' disease locus
Vaidya, B. (1999) · Human Molecular Genetics · doi:10.1093/hmg/8.7.1195 · Cited by 216
A prospective study of the incidence of childhood celiac disease
Hoffenberg, E. J., MacKenzie, T. A., Barriga, K. J., Eisenbarth, G. S., Bao, F., Haas, J. E., Erlich, H., Bugawan, T. L., Sokol, R. J., Taki, I., et al. (2003) · The Journal of Pediatrics · doi:10.1067/s0022-3476(03)00282-8 · Cited by 215
Thyroid Dysfunction in Patients With Type 1 Diabetes
Umpierrez, G. E., Latif, K. A., Murphy, M. B., Lambeth, H. C., Stentz, F., Bush, A., & Kitabchi, A. E. (2003) · Diabetes Care · doi:10.2337/diacare.26.4.1181 · Cited by 215
Clinical features and diagnosis of celiac disease
Dewar, D. H., & Ciclitira, P. J. (2005) · Gastroenterology · doi:10.1053/j.gastro.2005.02.010 · Cited by 213
Autoantibody “Subspecificity” in Type 1 Diabetes
Barker, J. M., Yu, J., Yu, L., Wang, J., Miao, D., Bao, F., Hoffenberg, E. J., Nelson, J. C., Gottlieb, P. A., Rewers, M., et al. (2005) · Diabetes Care · doi:10.2337/diacare.28.4.850 · Cited by 192
Self-citation
Coeliac disease and unfavourable outcome of pregnancy
Martinelli, P., Troncone, R., Paparo, F., Torre, P., Trapanese, E., Fasano, C., Lamberti, A., Budillon, G., Nardone, G., & Greco, L. (2000) · Gut · doi:10.1136/gut.46.3.332 · Cited by 188
Infertility and coeliac disease.
Collin, P., Vilska, S., Heinonen, P. K., Hällström, O., & Pikkarainen, P. H. (1996) · Gut · doi:10.1136/gut.39.3.382 · Cited by 181
Cutting Edge: NKG2D Is a Costimulatory Receptor for Human Naive CD8+ T Cells
Maasho, K., Opoku-Anane, J., Marusina, A., Coligan, J., & Borrego, F. (2005) · Journal of Immunology · doi:10.4049/jimmunol.174.8.4480 · Cited by 176
Autoimmune Adrenocortical Failure in Norway Autoantibodies and Human Leukocyte Antigen Class II Associations Related to Clinical Features
Myhre, A. G., Undlien, D. E., Løvås, K., Uhlving, S., Nedrebø, B. G., Fougner, K. J., Trovik, T. S., Sørheim, J. I., & Husebye, E. S. (2002) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.87.2.8192 · Cited by 159
Localization of the APECED protein in distinct nuclear structures
Björses, P. (1999) · Human Molecular Genetics · doi:10.1093/hmg/8.2.259 · Cited by 156
The natural history of adrenal function in autoimmune patients with adrenal autoantibodies
Betterle, C., Scalici, C., Presotto, F., Pedini, B., Moro, L., Rigon, F., & Mantero, F. (1988) · Journal of Endocrinology · doi:10.1677/joe.0.1170467 · Cited by 155
Can Tissue Transglutaminase Antibody Titers Replace Small-Bowel Biopsy to Diagnose Celiac Disease in Select Pediatric Populations?
Barker, C. C., Mitton, C., Jevon, G. P., & Mock, T. (2005) · PEDIATRICS · doi:10.1542/peds.2004-1392 · Cited by 151
Thyroid Autoimmunity in Children and Adolescents with Type 1 Diabetes mellitus
Holl, R. W., Böhm, B. O., Loos, U., Grabert, M., Heinze, E., & Homoki, J. (1999) · Hormone Research in Paediatrics · doi:10.1159/000023446 · Cited by 149
DRB1104 and DQ Alleles: Expression of 21-Hydroxylase Autoantibodies and Risk of Progression to Addison’s Disease1
Yu, L., Brewer, K. W., Gates, S. A., Wu, A.-Y. S., Wang, T., Babu, S. R., Gottlieb, P. A., Freed, B. M., Noble, J. A., Erlich, H. A., et al. (1999) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.84.1.5414 · Cited by 148
APECED mutations in the autoimmune regulator (AIRE) gene
Heino, M., Peterson, P., Kudoh, J., Shimizu, N., Antonarakis, S. E., Scott, H. S., & Krohn, K. J. E. (2001) · Human Mutation · doi:10.1002/humu.1176 · Cited by 141
Standardization of IVGTT to Predict IDDM
Bingley, P. J., Colman, P. G., Eisenbarth, G. S., Jackson, R. A., McCulloch, D. K., Riley, W. J., & Gale, E. A. (1992) · Diabetes Care · doi:10.2337/diacare.15.10.1313 · Cited by 133
Association of the lymphoid tyrosine phosphatase R620W variant with rheumatoid arthritis, but not Crohn's disease, in Canadian populations
Oene, M. V., Wintle, R. F., Liu, X., Yazdanpanah, M., Gu, X., Newman, W. G., Kwan, A. K. H., Johnson, B. E., Owen, J., Greer, W. L., et al. (2005) · Arthritis & Rheumatism · doi:10.1002/art.21123 · Cited by 131
The emerging role of the CTLA-4 gene in autoimmune endocrinopathies
Vaidya, B., & Pearce, S. H. S. (2004) · European Journal of Endocrinology · doi:10.1530/eje.0.1500619 · Cited by 123
21-hydroxylase autoantibodies in adult patients with endocrine autoimmune diseases are highly specific for Addison's disease
Falorni, A., LAURETI, S., Nikoshkov, A., Picchio, M. L., Hallengren, B., Vandewalle, C. L., Gorus, F., BELGIAN DIABETES REGISTRY, Tortoioli, C., Luthman, H., et al. (1997) · Clinical & Experimental Immunology · doi:10.1111/j.1365-2249.1997.262-ce1153.x · Cited by 117
APECED-causing mutations in AIRE reveal the functional domains of the protein
Halonen, M., Kangas, H., Rüppell, T., Ilmarinen, T., Ollila, J., Kolmer, M., Vihinen, M., Palvimo, J. J., Saarela, J., Ulmanen, I., et al. (2004) · Human Mutation · doi:10.1002/humu.20003 · Cited by 116
Dynamics of Diabetes-Associated Autoantibodies in Young Children with Human Leukocyte Antigen-Conferred Risk of Type 1 Diabetes Recruited from the General Population
Kukko, M., Kimpimäki, T., Korhonen, S., Kupila, A., Simell, S., Veijola, R., Simell, T., Ilonen, J., Simell, O., & Knip, M. (2005) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2004-1371 · Cited by 116
Association of MHC Class I chain-related A (MIC-A) gene polymorphism with Type I diabetes
Gambelunghe, G., Ghaderi, M., Cosentino, A., Falorni, A., Brunetti, P., Falorni, A., & Sanjeevi, C. B. (2000) · Diabetologia · doi:10.1007/s001250051336 · Cited by 116
Bone Mineral Density in Children With Untreated and Treated Celiac Disease
Bayrakçı, U. S., Yüce, A., Koçak, N., Demır, H., Saltık‐Temizel, İ. N., Gürakan, F., & Özen, H. (2003) · Journal of Pediatric Gastroenterology and Nutrition · doi:10.1097/00005176-200310000-00007 · Cited by 113
The Prevalence and Clinical Characteristics of Celiac Disease in Juvenile Diabetes in Wisconsin
Aktay, A. N., Lee, P. C., Kumar, V., Parton, E. A., Wyatt, D. T., & Werlin, S. L. (2001) · Journal of Pediatric Gastroenterology and Nutrition · doi:10.1097/00005176-200110000-00008 · Cited by 104
Schizophrenic symptoms and SPECT abnormalities in a coeliac patient: regression after a gluten‐free diet
SANTIS, A. D., Addolorato, G., Romito, A., Caputo, S., Giordano, A., Gambassi, G., Taranto, C., Manna, R., & Gasbarrini, A. (1997) · Journal of Internal Medicine · doi:10.1046/j.1365-2796.1997.00200.x · Cited by 101
Prevalence of IgA-Antiendomysium and IgA-Antigliadin Autoantibodies at Diagnosis of Insulin-Dependent Diabetes Mellitus in Swedish Children and Adolescents
Carlsson, A., Axelsson, I. E. M., Borulf, S. K., Bredberg, A. C. A., Lindberg, B. A., Sjöberg, K., & Ivarsson, S. A. (1999) · PEDIATRICS · doi:10.1542/peds.103.6.1248 · Cited by 101
Association Analysis of the Cytotoxic T Lymphocyte Antigen-4 (CTLA-4) and Autoimmune Regulator-1 (AIRE-1) Genes in Sporadic Autoimmune Addison’s Disease1
Vaidya, B., Imrie, H., Geatch, D. R., Perros, P., Ball, S. G., Baylis, P. H., Carr, D., Hurel, S. J., James, R. A., Kelly, W. F., et al. (2000) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.85.2.6369 · Cited by 101
Short stature and celiac disease: A relationship to consider even in patients with no gastrointestinal tract symptoms
CACCIARI, E., Salardi, S., Lazzari, R., Cicognani, A., Collina, A., Pirazzoli, P., TASSONI, P., Biasco, G., Corazza, G. R., & Cassio, A. (1983) · The Journal of Pediatrics · doi:10.1016/s0022-3476(83)80462-4 · Cited by 97
Prevalence of undiagnosed coeliac syndrome in osteoporotic women
Nuti, R., Martini, G., Valenti, R., Giovani, S., Salvadori, S., & Avanzati, A. (2001) · Journal of Internal Medicine · doi:10.1046/j.1365-2796.2001.00895.x · Cited by 95
AUTOANTIBODIES IN ADDISON'S DISEASE
Goudie, R. B., Anderson, J. R., Gray, K. N., & WHYTE, W. G. (1966) · The Lancet · doi:10.1016/s0140-6736(66)91070-1 · Cited by 95
MHC class I chain related gene A (MICA) modulates the development of coeliac disease in patients with the high risk heterodimer DQA1*0501/DQB1*0201
López‐Vázquez, A., Rodrigo, L., Fuentes, D., Riestra, S., Bousoño, C., Garcia-Fernandez, S., Martinez-Borra, J., Gonzalez, S., & Lopez-Larrea, C. (2002) · Gut · doi:10.1136/gut.50.3.336 · Cited by 95
Frequency of Hashimoto's thyroiditis in children with type 1 diabetes mellitus
Radetti, G., Paganini, C., Gentili, L., Bernasconi, S., Betterle, C., Borkenstein, M., Cvijović, K., Kadrnka-Lovrencić, M., Kržišnik, C., Battelino, T., et al. (1995) · Acta Diabetologica · doi:10.1007/bf00569570 · Cited by 94
Where have all the American celiacs gone?
Fasano, A. (1996) · Acta Paediatrica · doi:10.1111/j.1651-2227.1996.tb14242.x · Cited by 91
Extrapancreatic Autoimmune Manifestations in Type 1 Diabetes Patients and Their First-Degree Relatives
Hanukoglu, A., Mizrachi, A., Dalal, I., Admoni, O., Tenenbaum‐Rakover, Y., Bistritzer, Z., Levine, A., Somekh, E., Lehmann, D., Tuval, M., et al. (2003) · Diabetes Care · doi:10.2337/diacare.26.4.1235 · Cited by 90
First-phase insulin response in young healthy children at genetic and immunological risk for Type I diabetes
Keskinen, P., Korhonen, S., Kupila, A., Veijola, R., Erkkilä, S., Savolainen, H., Arvilommi, P., Simell, T. T., Ilonen, J., Knip, M., et al. (2002) · Diabetologia · doi:10.1007/s00125-002-0981-8 · Cited by 89
The influence of human leucocyte antigen (HLA) genes on autoimmune thyroid disease (AITD): results of studies in HLA‐DR3 positive AITD families
Ban, Y., Davies, T. F., Greenberg, D. A., Concepcion, E., & Tomer, Y. (2002) · Clinical Endocrinology · doi:10.1046/j.1365-2265.2002.01566.x · Cited by 89
Clinical Features of Children With Screening-Identified Evidence of Celiac Disease
Hoffenberg, E. J., Emery, L. M., Barriga, K. J., Bao, F., Taylor, J. H., Eisenbarth, G. S., Haas, J. E., Sokol, R. J., Taki, I., Norris, J. M., et al. (2004) · PEDIATRICS · doi:10.1542/peds.113.5.1254 · Cited by 88
High Level of Concordance Between Assays for Glutamic Acid Decarboxylase Antibodies: The First International Glutamic Acid Decarboxylase Antibody Workshop
Schmidli, R. S., Colman, P. G., Bonifacio, E., Franco Bottazzo, G., & Harrison, L. C. (1994) · Diabetes · doi:10.2337/diab.43.8.1005 · Cited by 86
Endocrine and Immunogenetic Testing in Individuals with Type 1 Diabetes and 21-Hydroxylase Autoantibodies: Addison’s Disease in a High-Risk Population
Barker, J. M., Ide, A., Hostetler, C., Yu, L., Miao, D., Fain, P. R., Eisenbarth, G. S., & Gottlieb, P. A. (2005) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2004-0874 · Cited by 83
Self-citation
Analysis of HLA genes in families with autoimmune diabetes and thyroiditis
Levin, L., Ban, Y., Concepcion, E., Davies, T. F., Greenberg, D. A., & Tomer, Y. (2004) · Human Immunology · doi:10.1016/j.humimm.2004.02.026 · Cited by 83
Mechanisms underlying celiac disease and its neurologic manifestations
Green, P. H. R., Alaedini, A., Sander, H. W., Brannagan, T. H., Latov, N., & Chin, R. L. (2005) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-004-4109-9 · Cited by 80
First-phase insulin release during the intravenous glucose tolerance test as a risk factor for type 1 diabetes
Chase, H. P., Cuthbertson, D. D., Dolan, L. M., KAUFMAN, F. R., Krischer, J. P., Schatz, D., White, N. H., Wilson, D. M., & Wolfsdorf, J. I. (2001) · The Journal of Pediatrics · doi:10.1067/mpd.2001.111274 · Cited by 78
Progression to diabetes in relatives with islet autoantibodies. Is it inevitable?
Gardner, S., Gale, E. A. M., Williams, A. J. K., Gillespie, K. M., Lawrence, K. E., Bottazzo, G. F., & Bingley, P. J. (1999) · Diabetes Care · doi:10.2337/diacare.22.12.2049 · Cited by 72
Autoimmune Addison's disease and 21-hydroxylase
Baumann-Antczak, A., Wedlock, D. N., Bednarek, J., KISO, Y., Krishnan, H., Fowler, S., Smith, B. R., & Furmaniak, J. (1992) · The Lancet · doi:10.1016/0140-6736(92)91513-8 · Cited by 71
Association of Insulin-Dependent Diabetes Mellitus and Celiac Disease: A Study Based on Serologic Markers
Vitoria, J. C., Castaño, L. A., Rica-Echevarría, I., Bilbao, J. R., Arrieta, A., & García‐Masdevall, M. D. (1998) · Journal of Pediatric Gastroenterology and Nutrition · doi:10.1097/00005176-199807000-00008 · Cited by 67
The CTLA4 region as a general autoimmunity factor: An extended pedigree provides evidence for synergy with the HLA locus in the etiology of type 1 diabetes mellitus, Hashimoto's thyroiditis and Graves' disease
Einarsdóttir, E., Söderström, I., Löfgren‐Burström, A., Haraldsson, S., Nilsson-Ardnor, S., Penha‐Gonçalves, C., Lind, L. K., Holmgren, G., Holmberg, M., Asplund, K., et al. (2003) · European Journal of Human Genetics · doi:10.1038/sj.ejhg.5200903 · Cited by 64
HLA-DQA1*0301-Associated Susceptibility for Autoimmune Polyglandular Syndrome Type II and III
Wallaschofski, H., Meyer, A., Tuschy, U., & Lohmann, T. (2003) · Hormone and Metabolic Research · doi:10.1055/s-2003-39059 · Cited by 63
Type 1 Diabetes Manifested Solely by 2-h Oral Glucose Tolerance Test Criteria
Greenbaum, C. J., Cuthbertson, D. D., Krischer, J. P., & the Diabetes Prevention Trial of Type 1 Diabetes Study Group (2001) · Diabetes · doi:10.2337/diabetes.50.2.470 · Cited by 61
Coeliac disease in children of short stature without gastrointestinal symptoms
Stenhammar, L., F�llstr�m, S. P., Jansson, G., Jansson, U., & Lindberg, T. (1986) · European Journal of Pediatrics · doi:10.1007/bf00446061 · Cited by 56
Metabolic Liver Disease: Working Group Report of the First World Congress of Pediatric Gastroenterology, Hepatology, and Nutrition
Perlmutter, D. L., de Azevedo, R. A., Kelly, D. A., Shepherd, R. W., & Tazawa, Y. (2002) · Journal of Pediatric Gastroenterology and Nutrition · doi:10.1097/00005176-200208002-00016 · Cited by 56
Adrenal cortex autoantibodies in subjects with normal adrenal function
Betterle, C., Coco, G., & Zanchetta, R. (2005) · Best Practice & Research Clinical Endocrinology & Metabolism · doi:10.1016/j.beem.2004.11.008 · Cited by 56
Fluctuating transglutaminase autoantibodies are related to histologic features of celiac disease
Liu, E., Bao, F., Barriga, K. J., Miao, D., Yu, L., Erlich, H. A., Haas, J. E., Eisenbarth, G. S., Rewers, M., & Hoffenberg, E. J. (2003) · Clinical Gastroenterology and Hepatology · doi:10.1053/s1542-3565(03)00180-0 · Cited by 56
Additional association of intra‐MHC genes, MICA and D6S273, with Addison's disease
Park, Y. S., Sanjeevi, C. B., Robles, D. T., Yu, L., Rewers, M., Gottlieb, P. A., Fain, P. R., & Eisenbarth, G. S. (2002) · Tissue Antigens · doi:10.1034/j.1399-0039.2002.600206.x · Cited by 54
Potential Role of NKG2D/MHC Class I-Related Chain A Interaction in Intrathymic Maturation of Single-Positive CD8 T Cells
Hüe, S., Monteiro, R. C., Berrih‐Aknin, S., & Caillat‐Zucman, S. (2003) · The Journal of Immunology · doi:10.4049/jimmunol.171.4.1909 · Cited by 54
Neurological abnormalities associated with celiac disease
Vaknin, A., Eliakim, R., Ackerman, Z., & Steiner, I. (2004) · Journal of Neurology · doi:10.1007/s00415-004-0550-9 · Cited by 52
The Temporal Relationship Between the Onset of Type 1 Diabetes and Celiac Disease: A Study Based on Immunoglobulin A Antitransglutaminase Screening
Peretti, N., Bienvenu, F., Bouvet, C., Fabien, N., Tixier, F., Thivolet, C. H., Levy, E. H., Chatelain, P. G., Lachaux, A., & Nicolino, M. P. (2004) · PEDIATRICS · doi:10.1542/peds.113.5.e418 · Cited by 51
MICA response to gliadin in intestinal mucosa from celiac patients
Mart�n-Pagola, A., P�rez-Nanclares, G., Ortiz, L., Vitoria, J. C., Hualde, I., Zaballa, R., Preciado, E., o, L. C., & Bilbao, J. R. (2004) · Immunogenetics · doi:10.1007/s00251-004-0724-8 · Cited by 49
Screening Patients with Insulin-Dependent Diabetes Mellitus for Adrenal Insufficiency
Brewer, K. W., Parziale, V. S., & Eisenbarth, G. S. (1997) · New England Journal of Medicine · doi:10.1056/nejm199707173370314 · Cited by 48
High prevalence of thyroid autoantibodies at diagnosis of insulin-dependent diabetes mellitus in Swedish children
Lindberg, B. A., Ericsson, U.-B. C., Ljung, R., & Ivarsson, S. A. (1997) · Journal of Laboratory and Clinical Medicine · doi:10.1016/s0022-2143(97)90108-6 · Cited by 40
HLA‐DRB1 and MHC class 1 chain‐related A haplotypes in Basque families with celiac disease
Bilbao, J. R., Martín‐Pagola, A., Vitoria, J. C., Zubillaga, P., Ortiz, L., & Castaño, L. A. (2002) · Tissue Antigens · doi:10.1034/j.1399-0039.2002.600109.x · Cited by 39
Need for quantitative assessment of transglutaminase autoantibodies for celiac disease in screening-identified children
Liu, E., Li, M., Bao, F., Miao, D., Rewers, M., Eisenbarth, G. S., & Hoffenberg, E. J. (2005) · The Journal of Pediatrics · doi:10.1016/j.jpeds.2004.11.028 · Cited by 36
Association between the transmembrane region polymorphism of MHC class I chain related Gene-A and type 1 diabetes mellitus in Sweden
Gupta, M., Ņikitina-Zaķe, L., Zarghami, M., Landin‐Olsson, M., Kockum, I. S., Lernmark, Å., & Sanjeevi, C. B. (2003) · Human Immunology · doi:10.1016/s0198-8859(03)00035-1 · Cited by 35
Polymorphisms of HLA Class II Predispose Children and Adolescents with Type 1 Diabetes Mellitus to Autoimmune Thyroid Disease
Kim, E. Y., Shin, C. H., & Yang, S. W. (2003) · Autoimmunity · doi:10.1080/0891693031000101279 · Cited by 35
Association of MICA-A5.1 allele with susceptibility to celiac disease in a family study
Rueda, B., Pascual, M., López‐Nevot, M. Á., Koeleman, B. P. C., Ortega, E., Maldonado, J., Lopez, M., & Martin, J. J. (2003) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2003.07228.x · Cited by 32
Hla-Dr/Dq Gene Variation in Nongoitrous Autoimmune Thyroiditis at the Serological and Molecular Level
Bogner, U., Badenhoop, K. W. J., Peters, H., Schmieg, D., Mayr, W. R., Usadel, K. H., & Schleusener, H. (1992) · Autoimmunity · doi:10.3109/08916939209083135 · Cited by 32
MICA-A5.1 allele is associated with atypical forms of celiac disease in HLA-DQ2-negative patients
Rodrigo, L. (2002) · Immunogenetics · doi:10.1007/s00251-001-0413-9 · Cited by 32
Prevalence of coeliac disease in siblings of patients with Type I diabetes is related to the prevalence of DQB1 * 02 allele
Saukkonen, T. T., Ilonen, J., Åkerblom, H. K., & Savilahti, E. (2001) · Diabetologia · doi:10.1007/s001250100591 · Cited by 30
Analysis of the Expression of MICA in Small Intestinal Mucosa of Patients with Celiac Disease
Martín‐Pagola, A., Ortiz, L., de Nanclares, G. P., Vitoria, J. C., Castaño, L. A., & Bilbao, J. R. (2003) · Journal of Clinical Immunology · doi:10.1023/b:joci.0000010426.16956.cc · Cited by 28
The High Prevalence of Autoantibodies to Tissue Transglutaminase in First-Degree Relatives of Patients With Type 1 Diabetes Is Not Associated With Islet Autoimmunity
Williams, A. J. K., Norcross, A. J., Lock, R. J., Unsworth, D. J., Gale, E. A., & Bingley, P. J. (2001) · Diabetes Care · doi:10.2337/diacare.24.3.504 · Cited by 27
HLA-DR3 and HLA-DR5 confer risk for autoantibody positivity against the thyroperoxidase (mic-TPO) antigen in healthy blood donors
Boehm, B. O., K�hnl, P., Lliger, C., Ketzler-Sasse, U., Holzberger, G., Seidl, S., B�uerle, R., Schifferdecker, E., & Usadell, K. H. (1993) · Journal of Molecular Medicine · doi:10.1007/bf00180105 · Cited by 26
Fifth International Serum Exchange Workshop for Insulin Autoantibody (IAA) Standardization
Greenbaum, C. J., Wilkin, T. J., Palmer, J. P., Agopian, M. S., Arnaiz‐Villena, A., Becker, D. J., Becker, F. O., Bosi, E., Bottazzo, G. F., Bouix, O., et al. (1992) · Diabetologia · doi:10.1007/bf00429105 · Cited by 24
MHC Class I Chain‐Related Gene Alleles 5 and 5.1 Are Transmitted More Frequently to Type 1 Diabetes Offspring in HBDI Families
Zake, L. N., Ghaderi, M., PARK, Y. S., Babu, S. R., Eisenbarth, G. S., & Sanjeevi, C. B. (2002) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2002.tb02993.x · Cited by 23
The Polyendocrine Deficiency Syndromes
Loriaux, D. L. (1985) · New England Journal of Medicine · doi:10.1056/nejm198506133122409 · Cited by 20
CHILDREN IN HOSPITAL
Stephen, E. (1958) · The Lancet · doi:10.1016/s0140-6736(58)92498-x · Cited by 10
Case report: an 11-year-old girl with tetany
Barker, J. M., & Travers, S. H. (2002) · Current Opinion in Pediatrics · doi:10.1097/00008480-200206000-00011 · Cited by 9
Self-citation

Sorted by citations

Type 1 diabetes
Atkinson, M. A., Eisenbarth, G. S., & Michels, A. W. (2014) · The Lancet · doi:10.1016/s0140-6736(13)60591-7 · Cited by 2,931
Epidemiology of type 1 diabetes
Maahs, D. M., West, N. A., Lawrence, J. M., & Mayer-Davis, E. J. (2010) · Endocrinology and Metabolism Clinics of North America · doi:10.1016/j.ecl.2010.05.011 · Cited by 1,092
Type 1 Diabetes: Etiology, Immunology, and Therapeutic Strategies
Van Belle, T. L., Coppieters, K. T., & Von Herrath, M. G. (2011) · Physiological Reviews · doi:10.1152/physrev.00003.2010 · Cited by 1,022
Detecting shared pathogenesis from the shared genetics of immune-related diseases
Zhernakova, A., van Diemen, C. C., & Wijmenga, C. (2009) · Nature Reviews Genetics · doi:10.1038/nrg2489 · Cited by 551
Prevalence and Relative Risk of Other Autoimmune Diseases in Subjects with Autoimmune Thyroid Disease
Boelaert, K., Newby, P. R., Simmonds, M. J., Holder, R. L., Carr-Smith, J. D., Heward, J. M., Manji, N., Allahabadia, A., Armitage, M., Chatterjee, K. V., et al. (2010) · The American Journal of Medicine · doi:10.1016/j.amjmed.2009.06.030 · Cited by 480

See all 350

Authors: Barker, J. M.
Affiliations: University of Colorado Anschutz (US)
Corresponding author: Barker, Jennifer M.
ORCID: Barker, Jennifer M.
Venue: The Journal of Clinical Endocrinology & Metabolism
Publisher: The Endocrine Society
Published: 2006-04
Volume: 91
Issue: 4
Pages: 1210-1217
ISSN: 0021-972X (ISSN-L)
1945-7197
DOI: 10.1210/jc.2005-1679
OpenAlex: W2036511637
Cited by: 350
References: 120
Citations by year: 2026: 7 · 2025: 6 · 2024: 16 · 2023: 9 · 2022: 13 · 2021: 12 · 2020: 11 · 2019: 13 · 2018: 25 · 2017: 8 · 2016: 12 · 2015: 24 · 2014: 20 · 2013: 28 · 2012: 25
FWCI: 14.05
Type: journal article
Language: en
Open access: closed
Locations: The Journal of Clinical Endocrinology & Metabolism (publishedVersion)
PubMed (publishedVersion)
Funders: National Institute of Allergy and Infectious Diseases (U19AI046374, AI 46374)
National Institute of Diabetes and Digestive and Kidney Diseases (P30DK057516, DK 57516, DK 32493, DK32083)
National Center for Research Resources (RR-00051, RR 00069, M01RR000069)
Topics: Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Diabetes and associated disorders
Health Sciences › Medicine › Gastroenterology › Celiac Disease Research and Management
Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Adrenal Hormones and Disorders
Keywords: type 1 diabetes, autoimmune thyroid disease, celiac disease, Addison's disease, autoimmune polyendocrine syndrome type 1, autoimmune polyendocrine syndrome type 2, genetic risk factors, major histocompatibility complex, HLA-DR, HLA-DQ, PTPN22, CTLA-4, autoantibodies, screening, natural history (disease)
MeSH terms: Adrenal Gland Diseases, Animals, Autoimmune Diseases, Celiac Disease, Diabetes Mellitus, Type 1, Genetic Testing, Humans, Risk Factors, Thyroiditis, Autoimmune

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Type 1 diabetes associated autoimmunity: natural history, genetic associations and screening

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks