Cited by 118Ovarian function and disordersDiabetes, Cardiovascular Risks, and LipoproteinsGenetic and Kidney Cyst Diseases

The DOI matches its Crossref record; 82 of the 83 references it cites were found in a registry or an index.

Relationship of Adolescent Polycystic Ovary Syndrome to Parental Metabolic Syndrome

Leibel, Natasha I., Baumann, Elizabeth E., Kocherginsky, Masha, Rosenfield, Robert L.·2006·The Journal of Clinical Endocrinology & Metabolism

DOI 10.1210/jc.2005-1707

Open this paper in CoChat — free account

Abstract

CONTEXT: We determined the relationship of metabolic syndrome (MBS) to polycystic ovary syndrome (PCOS). OBJECTIVE: We tested the hypothesis that parental MBS is related to the PCOS phenotype in their offspring. DESIGN/SETTING: We phenotyped for MBS and PCOS in our General Clinical Research Center. PATIENTS: Girls with PCOS, 12-19 yr old (n = 36, including one pair of siblings), and their parents (35 mothers, 19 fathers) were recruited from the Pediatric Endocrinology Clinic. Healthy girls, 12-19 yr old (n = 21), were recruited as a reference population. INTERVENTIONS: We measured anthropometrics, blood pressure, fasting lipids and androgens, oral glucose tolerance, and ultrasonographically determined polycystic ovary status. MAIN OUTCOME MEASURES: MBS in parents, and PCOS features in mothers, were related to the presence of PCOS features in probands. RESULTS: Fathers had strikingly high prevalence of excess adiposity (94% were obese or overweight) and MBS (79%). Premenopausal mothers more commonly had MBS (36%) than features of PCOS (< or =22%). Polycystic ovaries in proband offspring of premenopausal mothers were associated with maternal polycystic ovaries only in a minority of cases. Proband polycystic ovary status was completely concordant to fathers' MBS status (P = 0.008), but not their own or their mothers' MBS status, in families whose premenopausal mothers lacked polycystic ovaries. Proband prevalence of MBS was 27.8%, 3-fold greater than expected for obesity status. CONCLUSION: Familial factors related to paternal MBS seem to be fundamental to the pathogenesis of PCOS.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1210/jc.2005-1707

Cites

82 of 82 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Homeostasis model assessment: insulin resistance and ?-cell function from fasting plasma glucose and insulin concentrations in man
Matthews, D. R., Hosker, J. P., Rudenski, A. S., Naylor, B. A., Treacher, D. F., & Turner, R. C. (1985) · Diabetologia · doi:10.1007/bf00280883 · Cited by 31,502
Summary of the second report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel II)
Grundy, S. M., Bilheimer, D. W., Chait, A., Clark, L. T., Denke, M. A., Havel, R. J., Hazzard, W. R., Hulley, S. B., Hunninghake, D. B., Kreisberg, R. A., et al. (1993) · JAMA · doi:10.1001/jama.269.23.3015 · Cited by 27,944
Practical Statistics for Medical Research
Altman, D. G. (1990) · doi:10.1201/9780429258589 · Cited by 10,668
Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome
(2004) · Fertility and Sterility · doi:10.1016/j.fertnstert.2003.10.004 · Cited by 9,050
The metabolic syndrome
Eckel, R. H., Alberti, K., Grundy, S. M., & Zimmet, P. (2010) · The Lancet · doi:10.1016/s0140-6736(09)61794-3 · Cited by 6,317
Definition of Metabolic Syndrome: Report of the National Heart, Lung, and Blood Institute/American Heart Association Conference on Scientific Issues Related to Definition
Grundy, S. M., Brewer, H. B., Cleeman, J. I., Smith, S. C., & Lenfant, C. (2004) · Circulation · doi:10.1161/01.cir.0000111245.75752.c6 · Cited by 5,982
Prevalence of obesity, diabetes, and obesity-related health risk factors, 2001
Mokdad, A. H., Ford, E. S., Bowman, B. A., Dietz, W. H., Vinicor, F., Bales, V. S., & Marks, J. S. (2003) · JAMA · doi:10.1001/jama.289.1.76 · Cited by 5,866
Practical Statistics for Medical Research.
Bartko, J. J., & Altman, D. G. (1992) · Journal of the American Statistical Association · doi:10.2307/2290246 · Cited by 4,834
Prevalence of overweight and obesity among US children, adolescents, and adults, 1999-2002.
Hedley, A. A., Ogden, C., Johnson, C. L., Carroll, M., Curtin, L. R., & Flegal, K. (2004) · Journal of the American Medical Association (JAMA) · doi:10.1001/jama.291.23.2847 · Cited by 4,670
The Prevalence and Features of the Polycystic Ovary Syndrome in an Unselected Population
Azziz, R., Woods, K. S., Reyna, R., Key, T. J., Knochenhauer, E. S., & Yıldız, B. O. (2004) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2003-032046 · Cited by 2,715

Show all 83 references

Sorted by citations

The Diagnosis of Polycystic Ovary Syndrome during Adolescence
Witchel, S. F., Oberfield, S., Rosenfield, R. L., Codner, E., Bonny, A., Ibáñez, L., Pena, A., Horikawa, R., Gomez-Lobo, V., Joel, D., et al. (2015) · Hormone Research in Paediatrics · doi:10.1159/000375530 · Cited by 3,113
Self-citation
The pathogenesis of polycystic ovary syndrome (PCOS): the hypothesis of PCOS as functional ovarian hyperandrogenism revisited
Rosenfield, R. L., & Ehrmann, D. A. (2016) · Endocrine Reviews · doi:10.1210/er.2015-1104 · Cited by 1,603
Self-citation
Polycystic ovary syndrome
Norman, R. J., Dewailly, D., Legro, R. S., & Hickey, T. E. (2007) · The Lancet · doi:10.1016/s0140-6736(07)61345-2 · Cited by 1,360
Chronic high-fat diet in fathers programs β-cell dysfunction in female rat offspring
Ng, S.-F., Lin, R. C. Y., Laybutt, D. R., Barres, R., Owens, J. A., & Morris, M. J. (2010) · Nature · doi:10.1038/nature09491 · Cited by 1,327
Impaired Glucose Tolerance, Type 2 Diabetes and Metabolic Syndrome in Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis
Moran, L. J., Misso, M. L., Wild, R. A., & Norman, R. J. (2010) · Human Reproduction Update · doi:10.1093/humupd/dmq001 · Cited by 1,108
Polycystic ovary syndrome
Franks, S. (1997) · Archives of Disease in Childhood · doi:10.1136/adc.77.1.89 · Cited by 802
Paternal obesity initiates metabolic disturbances in two generations of mice with incomplete penetrance to the F 2 generation and alters the transcriptional profile of testis and sperm microRNA content
Fullston, T., Teague, E. M. C. O., Palmer, N. O., DeBlasio, M. J., Mitchell, M., Corbett, M., Print, C. G., Owens, J. A., & Lane, M. (2013) · The FASEB Journal · doi:10.1096/fj.12-224048 · Cited by 600
Ethnicity, Obesity and the Prevalence of Impaired Glucose Tolerance and Type 2 Diabetes in PCOS: A Systematic Review and Meta-Regression
Kakoly, N. S., Khomami, M. B., Joham, A. E., Cooray, S. D., Misso, M. L., Norman, R. J., Harrison, C. L., Ranasinha, S., Teede, H. J., & Moran, L. J. (2018) · Human Reproduction Update · doi:10.1093/humupd/dmy007 · Cited by 384
Testosterone, sex hormone-binding globulin and the metabolic syndrome: A systematic review and meta-analysis of observational studies
Brand, J. S., van der Tweel, I., Grobbee, D. E., Emmelot-Vonk, M. H., & van der Schouw, Y. T. (2011) · International Journal of Epidemiology · doi:10.1093/ije/dyq158 · Cited by 334
Metabolic syndrome in polycystic ovary syndrome: a systematic review, meta‐analysis and meta‐regression
Lim, S. S., Kakoly, N. S., Tan, J. W. J., Fitzgerald, G., Bahri Khomami, M., Joham, A. E., Cooray, S. D., Misso, M. L., Norman, R. J., Harrison, C. L., et al. (2019) · Obesity Reviews · doi:10.1111/obr.12762 · Cited by 316
Identifying Children at Risk for Polycystic Ovary Syndrome
Rosenfield, R. L. (2007) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2006-2012 · Cited by 288
Self-citation
The Diagnosis of Polycystic Ovary Syndrome in Adolescents
Rosenfield, R. L. (2015) · PEDIATRICS · doi:10.1542/peds.2015-1430 · Cited by 201
Self-citation
Metabolic complications of obesity in childhood and adolescence: more than just diabetes
Nathan, B. M., & Moran, A. (2008) · Current Opinion in Endocrinology Diabetes and Obesity · doi:10.1097/med.0b013e3282f43d19 · Cited by 174
Adolescent Anovulation: Maturational Mechanisms and Implications
Rosenfield, R. L. (2013) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2013-1770 · Cited by 139
Self-citation
Prevalence of Metabolic Syndrome and Related Characteristics in Obese Adolescents with and without Polycystic Ovary Syndrome
Rossi, B., Sukalich, S., Droz, J., Griffin, A., Cook, S., Blumkin, A., Guzick, D. S., & Hoeger, K. M. (2008) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2008-1198 · Cited by 120
Adverse effects of the common treatments for polycystic ovary syndrome: a systematic review and meta-analysis
Domecq, J. P., Prutsky, G., Mullan, R. J., Sundaresh, V., Wang, A. T., Erwin, P. J., Welt, C., Ehrmann, D., Montori, V. M., & Murad, M. H. (2013) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2013-2374 · Cited by 115
The Metabolic Syndrome in Polycystic Ovary Syndrome
Essah, P. A., Wickham, E. P., & Nestler, J. E. (2007) · Clinical Obstetrics & Gynecology · doi:10.1097/grf.0b013e31802f3547 · Cited by 113
Evidence that obesity and androgens have independent and opposing effects on gonadotropin production from puberty to maturity
Rosenfield, R. L., & Bordini, B. (2010) · Brain Research · doi:10.1016/j.brainres.2010.08.088 · Cited by 101
Self-citation
Metabolic syndrome, hypertension, and hyperlipidemia in mothers, fathers, sisters, and brothers of women with polycystic ovary syndrome: a systematic review and meta-analysis
Yılmaz, B., Vellanki, P., Ata, B., & Yıldız, B. O. (2018) · Fertility and Sterility · doi:10.1016/j.fertnstert.2017.10.018 · Cited by 101
The risk of metabolic syndrome in polycystic ovary syndrome: A systematic review and meta‐analysis
Behboudi‐Gandevani, S., Amiri, M., Yarandi, R. B., Noroozzadeh, M., Farahmand, M., Dovom, M. R., & Tehrani, F. R. (2017) · Clinical Endocrinology · doi:10.1111/cen.13477 · Cited by 89
Microcirculation and the Metabolic Syndrome
Wiernsperger, N. F., Nivoit, P., Kraemer‐Aguiar, L. G., & Bouskela, E. (2007) · Microcirculation · doi:10.1080/10739680701285617 · Cited by 81
Current concepts of polycystic ovary syndrome pathogenesis
Rosenfield, R. L. (2020) · Current Opinion in Pediatrics · doi:10.1097/mop.0000000000000945 · Cited by 77
Self-citation
Age of Onset of Polycystic Ovarian Syndrome in Girls May Be Earlier Than Previously Thought
Bronstein, J. Z., Tawdekar, S., Liu, Y., Pawelczak, M., DAVID, R. R., & Shah, B. C. (2011) · Journal of Pediatric and Adolescent Gynecology · doi:10.1016/j.jpag.2010.06.003 · Cited by 76
High Prevalence of Metabolic Syndrome in First-Degree Male Relatives of Women with Polycystic Ovary Syndrome Is Related to High Rates of Obesity
Coviello, A. D., Sam, S., Legro, R. S., & Dunaif, A. E. (2009) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2009-1333 · Cited by 77
Using the Androgen Excess–PCOS Society Criteria to Diagnose Polycystic Ovary Syndrome and the Risk of Metabolic Syndrome in Adolescents
Roe, A. H., Prochaska, E. C., Smith, M. E., Sammel, M. D., & Dokras, A. (2012) · The Journal of Pediatrics · doi:10.1016/j.jpeds.2012.11.019 · Cited by 74
Brothers of women with polycystic ovary syndrome are characterised by impaired glucose tolerance, reduced insulin sensitivity and related metabolic defects
Baillargeon, J., & Carpentier, A. C. (2007) · Diabetologia · doi:10.1007/s00125-007-0831-9 · Cited by 72
Early origins of polycystic ovary syndrome
Dumesic, D. A., Schramm, R. D., & Abbott, D. H. (2005) · Reproduction Fertility and Development · doi:10.1071/rd04092 · Cited by 67
Puberty and its disorders in the female
Rosenfield, R. L., Cooke, D. W., & Radovick, S. (2014) · Elsevier eBooks · doi:10.1016/b978-1-4557-4858-7.00024-x · Cited by 67
Self-citation
Identification and treatment of metabolic complications in pediatric obesity
Ode, K. L., Frohnert, B. I., & Nathan, B. M. (2009) · Reviews in Endocrine and Metabolic Disorders · doi:10.1007/s11154-009-9115-7 · Cited by 64
Polycystic ovary syndrome and its impact on women’s quality of life: More than just an endocrine disorder
Mousa, S., Brady, Mousa, S., & Mousa (2009) · Drug Healthcare and Patient Safety · doi:10.2147/dhps.s4388 · Cited by 63
Polycystic ovary syndrome in obese adolescents
Stanley, T. L., & Misra, M. (2008) · Current Opinion in Endocrinology Diabetes and Obesity · doi:10.1097/med.0b013e3282f41d55 · Cited by 62
Presence of polycystic ovary syndrome is associated with longer anogenital distance in adult Mediterranean women
Sánchez-Ferrer, M. L., Mendiola, J., Peñalver, A. I. H., Corbalán‐Biyang, S., Carmona‐Barnosi, A., Prieto‐Sánchez, M. T., Nieto, A., & Torres-Cantero, A. M. (2017) · Human Reproduction · doi:10.1093/humrep/dex274 · Cited by 64
Metabolic syndrome and its components among women with polycystic ovary syndrome: a systematic review and meta-analysis
Hallajzadeh, J., Khoramdad, M., Karamzad, N., Almasi‐Hashiani, A., Janati, A., Ayubi, E., Pakzad, R., Sullman, M. J. M., & Safiri, S. (2018) · Journal of Cardiovascular and Thoracic Research · doi:10.15171/jcvtr.2018.10 · Cited by 59
Associations of Birthweight and Gestational Age with Reproductive and Metabolic Phenotypes in Women with Polycystic Ovarian Syndrome and Their First-Degree Relatives
Legro, R. S., Roller, R. L., Dodson, W. C., Stetter, C. M., Kunselman, A. R., & Dunaif, A. E. (2009) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2009-1849 · Cited by 54
31. Polycystic ovary syndrome and the metabolic syndrome
Hunter, T., & Hart, R. J. (2014) · Wageningen Academic Publishers eBooks · doi:10.3920/978-90-8686-767-7.031 · Cited by 51
Diabetes mellitus and insulin resistance in mothers, fathers, sisters, and brothers of women with polycystic ovary syndrome: a systematic review and meta-analysis
Yılmaz, B., Vellanki, P., Ata, B., & Yıldız, B. O. (2018) · Fertility and Sterility · doi:10.1016/j.fertnstert.2018.04.024 · Cited by 53
Diagnosis and Challenges of Polycystic Ovary Syndrome in Adolescence
Agapova, S. E., Cameo, T., Sopher, A. B., & Oberfield, S. E. (2014) · Seminars in Reproductive Medicine · doi:10.1055/s-0034-1371091 · Cited by 44
Puberty and Its Disorders in the Female
Rosenfield, R. L., Cooke, D. W., & Radovick, S. (2008) · Elsevier eBooks · doi:10.1016/b978-141604090-3.50019-3 · Cited by 44
Self-citation
Menstrual Health and the Metabolic Syndrome in Adolescents
Tfayli, H. M., & Arslanian, S. A. (2008) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1429.024 · Cited by 40
Cardiometabolic abnormalities in the polycystic ovary syndrome: Pharmacotherapeutic insights
Westerveld, H. E., Hoogendoorn, M., de Jong, A. W. F., Goverde, A. J., Fauser, B. C. J. M., & Dallinga‐Thie, G. M. (2008) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2008.04.009 · Cited by 38
What do we know about metabolic syndrome in adolescents with PCOS?
Cırık, D. A., & Dilbaz, B. (2014) · Journal of the Turkish-German Gynecological Association · doi:10.5152/jtgga.2014.95776 · Cited by 38
Features of Polycystic Ovary Syndrome in adolescence.
Tsikouras, P. N., Liatsikos, S. A., Manav, B., Zervoudis, S., Poiană, C., Nikolaos, T. P., Petros, P., Dimitraki, M., Koukouli, C., Galazios, G. C., et al. (2015) · Europe PMC (PubMed Central) · Cited by 36
Insulin resistance and its relationship with high molecular weight adiponectin in adolescents with polycystic ovary syndrome and a maternal history of polycystic ovary syndrome
Cankaya, S., Demir, B., Aksakal, S. E., Dilbaz, B., Demirtas, C., & Göktolga, Ü. (2014) · Fertility and Sterility · doi:10.1016/j.fertnstert.2014.05.032 · Cited by 33
Female offspring sired by diet induced obese male mice display impaired blastocyst development with molecular alterations to their ovaries, oocytes and cumulus cells
Fullston, T., Shehadeh, H., Sandeman, L., Kang, W. X., Wu, L., Robker, R. L., McPherson, N. O., & Lane, M. (2015) · Journal of Assisted Reproduction and Genetics · doi:10.1007/s10815-015-0470-x · Cited by 33
Polycystic Ovary Syndrome in Adolescents
O'Brien, R. F., & Emans, S. J. (2008) · Journal of Pediatric and Adolescent Gynecology · doi:10.1016/j.jpag.2007.07.007 · Cited by 32
Prevalence of metabolic syndrome in the family members of women with polycystic ovary syndrome from North India
Ganie, M., Shabir, I., Zargar, M. A., Bhat, D., Mir, R., Jan, A., Shah, Z. A., Jan, V., Rasool, R., & Naqati, A. (2014) · Indian Journal of Endocrinology and Metabolism · doi:10.4103/2230-8210.131186 · Cited by 29
Prevalence and risk of metabolic syndrome in adolescent Indian girls with polycystic ovary syndrome using the 2009 ‘joint interim criteria’
Bhattacharya, S. M., & Jha, A. (2011) · Journal of obstetrics and gynaecology research · doi:10.1111/j.1447-0756.2010.01516.x · Cited by 28
Intergenerational Associations of Chronic Disease and Polycystic Ovary Syndrome
Davies, M. J., Marino, J. L., Willson, K. J., March, W. A., & Moore, V. (2011) · PLoS ONE · doi:10.1371/journal.pone.0025947 · Cited by 23
Puberty in the Female and Its Disorders
Rosenfield, R. L., Cooke, D. W., & Radovick, S. (2021) · Elsevier eBooks · doi:10.1016/b978-0-323-62520-3.00016-6 · Cited by 23
Self-citation
Early onset adiposity: a pathway to polycystic ovary syndrome in adolescents?
Diamanti‐Kandarakis, E., Christakou, C. D., Kandaraki, E., & Alexandraki, K. (2007) · PubMed · Cited by 20
Pregnancy complications and metabolic disease in women with clomiphene citrate-resistant anovulation randomized to receive laparoscopic electrocautery of the ovaries or ovulation induction with gonadotropins: a 10-year follow-up
Nahuis, M. J., Oude Lohuis, E. J., Bayram, N., Hompes, P. G. A., Oosterhuis, G. J. E., van der Veen, F., Mol, B. W. J., & van Wely, M. (2014) · Fertility and Sterility · doi:10.1016/j.fertnstert.2013.09.004 · Cited by 18
The expression profile of WNT/β-catanin signalling genes in human oocytes obtained from polycystic ovarian syndrome (PCOS) patients
Ismail, A. B., Naji, M. ’. S., Nebih, İ., Tuncel, G., Özbakır, B., Temel, Ş. G., Tulay, P., Mocan, G., & Ergören, M. Ç. (2022) · Zygote · doi:10.1017/s0967199422000028 · Cited by 18
Family background of Diabetes Mellitus, obesity and hypertension affects the phenotype and first symptom of patients with PCOS
Kulshreshtha, B., Singh, S., & Arora, A. (2013) · Gynecological Endocrinology · doi:10.3109/09513590.2013.829446 · Cited by 18
Comparison of metabolic and obesity biomarkers between adolescent and adult women with polycystic ovary syndrome
de Medeiros, S. F., de Medeiros, M. A. S., Barbosa, B. B., Yamamoto, M. M. W., & Maciel, G. A. R. (2020) · Archives of Gynecology and Obstetrics · doi:10.1007/s00404-020-05867-x · Cited by 18
Chronic anovulation and the polycystic ovary syndrome
KASE, N. G. (2013) · Cambridge University Press eBooks · doi:10.1017/cbo9781139003254.012 · Cited by 16
Single‐cell transcriptome analysis reveals that maternal obesity affects DNA repair, histone methylation, and autophagy level in mouse embryos
Pan, M., Zhu, C., Ju, J., Xu, Y., Luo, S., Sun, S., & Ou, X. (2020) · Journal of Cellular Physiology · doi:10.1002/jcp.30201 · Cited by 16
Hyperandrogenism, Hirsutism, and Polycystic Ovary Syndrome
Rosenfield, R. L., Barnes, R. B., & Ehrmann, D. A. (2015) · Elsevier eBooks · doi:10.1016/b978-0-323-18907-1.00133-5 · Cited by 17
Self-citation
The Search for the Causes of Common Hyperandrogenism, 1965 to Circa 2015
Rosenfield, R. L. (2024) · Endocrine Reviews · doi:10.1210/endrev/bnae007 · Cited by 16
Self-citation
Interventional Studies for Polycystic Ovarian Syndrome in Children and Adolescents
Vuguin, P. M. (2010) · Pediatric Health · doi:10.2217/phe.09.69 · Cited by 14
Arterial hypertension and metabolic profile in patients with polycystic ovary syndrome
de Oliveira, R. D. S. M., Redorat, R. G., Ziehe, G. H., Mansur, V. A., & Conceição, F. L. (2013) · Revista Brasileira Ginecologia e Obstetrícia · doi:10.1590/s0100-72032013000100005 · Cited by 12
Gonadal dysfunction in morbidly obese adolescent girls
Chin, V. L., Censani, M., Lerner, S. E., Conroy, R., Oberfield, S. E., McMahon, D. J., Zitsman, J. L., & Fennoy, I. (2014) · Fertility and Sterility · doi:10.1016/j.fertnstert.2013.12.046 · Cited by 12
Analyzing the Impact of FSHR Variants on Polycystic Ovary Syndrome—a Case-Control Study in Punjab
Kaur, M., Singh, S., Kaur, R., Beri, A., & Kaur, A. (2023) · Reproductive Sciences · doi:10.1007/s43032-023-01194-z · Cited by 11
Metabolic and reproductive characteristics of first-degree relatives of women with self-reported oligo-amenorrhoea and hirsutism
Torvinen, A., Koivunen, R. M., Pouta, A. M., Franks, S., Martikainen, H. K., Bloigu, A. H., Hartikainen, A., McCarthy, M. I., Ruokonen, A., Järvelin, M., et al. (2010) · Gynecological Endocrinology · doi:10.3109/09513590.2010.520375 · Cited by 11
Le syndrome des ovaires polykystiques (SOPK)
Torre, A., & Fernandez, H. (2007) · Journal de gynécologie, obstétrique et biologie de la reproduction. Supplément/Journal de gynécologie obstétrique et biologie de la reproduction · doi:10.1016/j.jgyn.2007.04.002 · Cited by 11
The assessment of thyroid autoantibody levels in euthyroid polycystic ovary syndrome patients
Hepşen, S., Karaköse, M., Çakal, E., Öztekin, S., Ünsal, İ. Ö., Akhanlı, P., Uçan, B., & Özbek, M. (2018) · Journal of the Turkish-German Gynecological Association · doi:10.4274/jtgga.2018.0001 · Cited by 10
On the Intimate Relationship of Adiposity to Polycystic Ovary Syndrome
Rosenfield, R. L., & Dumesic, D. A. (2025) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/clinem/dgaf527 · Cited by 11
Self-citation
Can a mother’s polycystic ovary syndrome (PCOS)-related symptoms be used to predict the future clinical profile of PCOS in her adolescent daughter? A pilot study
Līdaka, L., Grasmane, A., Lazdāne, G., Dzīvīte-Krišāne, I., Gailīte, L., & Vīberga, I. (2020) · The European Journal of Contraception & Reproductive Health Care · doi:10.1080/13625187.2020.1795118 · Cited by 9
An Ecosocial Perspective on Barriers to the Management of Polycystic Ovary Syndrome Among Women in Urban India
Pathak, G. (2021) · Journal of Health Management · doi:10.1177/09720634211011558 · Cited by 8
Sentiment Analysis and Topic Modeling on Polycystic Ovary Syndrome from Online Forum Using Deep Learning Approach
Raagel, K. G., Mappillairaju, B., Sharma, K. S. N., Manikandan, P., & Muthu, C. (2023) · Wireless Personal Communications · doi:10.1007/s11277-023-10795-5 · Cited by 7
The role of family history in clinical symptoms and therapeutic outcomes of women with polycystic ovary syndrome
Hu, Z., Wang, Y., Qiao, J., Li, M., Chi, H., & Chen, X. (2009) · International Journal of Gynecology & Obstetrics · doi:10.1016/j.ijgo.2009.08.004 · Cited by 7
Polycystic Ovarian Syndrome
Hernández, M. I., & Verónica Mericq, G. (2009) · doi:10.1002/9781444316728.ch21 · Cited by 7
Impact of CYP19A1 genetic variations on polycystic ovary syndrome: findings from a case-control study
Chaudhary, H., Patel, J. K., Jain, N. K., Panchal, S., Nanavati, P., Singh, M., Laddha, N. C., & Joshi, R. G. (2025) · F&S Science · doi:10.1016/j.xfss.2025.03.005 · Cited by 6
Prevalance and role of Melatonin on PCOS in its treatment using Herbal Drugs
Ahamed, S., Sumitra, M., & Chitra, V. (2021) · Research Journal of Pharmacy and Technology · doi:10.52711/0974-360x.2021.00877 · Cited by 6
Phenotypic Characterization of Polycystic Ovary Syndrome in Adolescents Based on Menstrual Irregularity
Javed, A., Kumar, S., Simmons, P. S., & Lteif, A. N. (2015) · Hormone Research in Paediatrics · doi:10.1159/000435883 · Cited by 6
Family history of menstrual irregularity or diabetes mellitus enhances the susceptibility to polycystic ovary syndrome among subjects harboring rs7903146 genetic variant of TCF7L2
Rashid, R., Shah, I. A., Asrar, M. M., Godha, M., Ganai, B. A., & Ganie, M. A. (2022) · Journal of Diabetes & Metabolic Disorders · doi:10.1007/s40200-022-01050-y · Cited by 6
EFFECT OF METFORMIN THERAPY IN FEMALE VISITING DERMATOLOGIST FOR ACNE VULGARIS HAVING ENDOCRINE AND SONOGRAPHIC CHARACTERISTICS OF POLYCYSTIC OVARY SYNDROME (PCOS)
Ty, M., Shah, & Rk, G. (2013) · Cited by 6
Hyperandrogenism, Hirsutism, and Polycystic Ovary Syndrome
Barnes, R. B., Ehrmann, D. A., & Rosenfield, R. L. (2010) · Elsevier eBooks · doi:10.1016/b978-1-4160-5583-9.00132-5 · Cited by 6
Self-citation
Diabetes advice for women with polycystic ovary syndrome: prevention, prevention, prevention
Mani, H., Khunti, K., Levy, M. J., & Davies, M. J. (2013) · Diabetes Management · doi:10.2217/dmt.13.54 · Cited by 5
The prevalence of metabolic syndrome in clomiphene citrate resistant polycystic ovary syndrome
Verit, F. F. (2012) · Gynecological Endocrinology · doi:10.3109/09513590.2011.593931 · Cited by 5
Polycystic ovary syndrome
Ahonen, K. A. (2010) · The Nurse Practitioner · doi:10.1097/01.npr.0000387144.87541.c4 · Cited by 5
Single Nucleotide Polymorphisms (SNPs) and Variable Number Tandem Repeats (VNTRs) in mtDNA D-loop and CO II- tRNALys Intergenic Region with PCOS
Zhi-ping, H. U., Ying, W. A. N. G., Mao, W., Zhang, X., Qiao, J., & Zhang, Q. (2011) · Chin J Reprod Contracep · doi:10.1016/s1001-7844(12)60008-x · Cited by 4
The metabolic effects of drugs used for the treatment of polycystic ovary syndrome
Karaköse, M., Çakal, E., Ertan, K., & Delibaşı, T. (2013) · Journal of the Turkish-German Gynecological Association · doi:10.5152/jtgga.2013.57701 · Cited by 3
The link between polycystic ovary syndrome and Type 2 diabetes: what do we know today?
Sathyapalan, T., & Atkin, S. L. (2011) · Diabetes Management · doi:10.2217/dmt.11.59 · Cited by 3
Clinical utility of FAI and SHBG in differentiating PCOS from anovulatory cycles in adolescent girls
Özer, E., Taş, D., Gündoğan, S. Ç., Boyraz, M., & Gürbüz, F. (2025) · Frontiers in Pediatrics · doi:10.3389/fped.2025.1581060 · Cited by 2
Menstrual Disorders and Hyperandrogenism in Adolescence
DiVall, S. A., & Rosenfield, R. L. (2013) · Humana Press eBooks · doi:10.1007/978-1-60761-395-4_25 · Cited by 2
Self-citation
A Study on the Pattern of Genetic Inheritance of Polycystic Ovarian Syndrome
Muralidhara, K. D., Adhikari, P., & Dv, M. (2014) · Journal of Advances in Medicine and Medical Research · doi:10.9734/bjmmr/2015/13461 · Cited by 2
Fetal Origins of Polycystic Ovary Syndrome
Abbott, D. H., Bruns, C. M., Barnett, D. K., Tarantal, A. F., Hoffmann, S. M., Zhou, R., Levine, J. E., & Dumesic, D. A. (2008) · Humana Press eBooks · doi:10.1007/978-1-59745-108-6_6 · Cited by 2
Menstrual Disorders and Hyperandrogenism in Adolescence
DiVall, S. A., & Rosenfield, R. L. (2018) · Springer eBooks · doi:10.1007/978-3-319-73782-9_28 · Cited by 2
Self-citation
Polycystic Ovarian Syndrome
Christou, M., Mintziori, G., Goulis, D. G., & Tarlatzis, B. C. (2023) · ISGE series · doi:10.1007/978-3-031-22378-5_8 · Cited by 2
Adolescent polycystic ovary syndrome: pathophysiology and implications of the disease
Gupta, S., Chen, D. K., Chandra, A., Metterle, L., Kesavan, S., & Agarwal, A. K. (2009) · Cited by 1
Clinical Features
Stracquadanio, M., & Ciotta, L. (2015) · Springer eBooks · doi:10.1007/978-3-319-16760-2_3 · Cited by 1
Adolesanda Polikistik Over Sendromu
Şahi̇n, L., & Aygün, B. (2013) · DergiPark (Istanbul University) · Cited by 1
Epidemiological investigation and economic analysis of Polycystic Ovary Syndrome (PCOS) for women in the UK
Ding, T. (2018) · UCL Discovery (University College London) · Cited by 1
Skin Manifestations of Paediatric Metabolic Syndrome
Holzer, G., & Volc‐Platzer, B. (2019) · Harper's Textbook of Pediatric Dermatology · doi:10.1002/9781119142812.ch72 · Cited by 1
Differentiating PCOS from Anovulatory Cycles in Adolescents: A Comprehensive Evaluation of FAI, SHBG, and LH/FSH RatioPreprint
Özer, E., Taş, D., Gündoğan, S. Ç., Boyraz, M., & GÜRBÜZ, F. (2024) · Research Square · doi:10.21203/rs.3.rs-4945396/v1 · Cited by 1
Gynäkologische Erkrankungen
Raile, V., & Wachter, I. (2007) · Elsevier eBooks · doi:10.1016/b978-343723200-8.50035-4
Pregnancy in PCOS Women and their History of Diabetes
Lauszus, M. G. F. F. (2014) · Journal of Metabolic Syndrome · doi:10.4172/2167-0943.1000163
The Diagnosis of Polycystic Ovary Syndrome during Adolescence
Marina, P., & Beirut, L. (2016)
Avaliação da prevalência e das características da síndrome dos ovários policísticos em adolescentes obesas
Ybarra, M. (2016) · doi:10.11606/d.5.2016.tde-23082016-105819
14.9 Polyzystisches Ovarsyndrom
Merki-Feld, G. S. (2015) · Thieme eBooks · doi:10.1055/b-0035-104189

Authors: Leibel, N. I., Baumann, E. E., Kocherginsky, M., & Rosenfield, R. L.
Affiliations: University of Chicago (US)
Corresponding author: Rosenfield, Robert L.
ORCID: Kocherginsky, Masha
Rosenfield, Robert L.
Venue: The Journal of Clinical Endocrinology & Metabolism
Publisher: The Endocrine Society
Published: 2006-04
Volume: 91
Issue: 4
Pages: 1275-1283
ISSN: 0021-972X (ISSN-L)
1945-7197
DOI: 10.1210/jc.2005-1707
OpenAlex: W2129794022
Cited by: 118
References: 83
Citations by year: 2026: 1 · 2025: 4 · 2024: 3 · 2023: 4 · 2022: 6 · 2021: 5 · 2020: 4 · 2019: 1 · 2018: 10 · 2017: 2 · 2016: 3 · 2015: 8 · 2014: 9 · 2013: 12 · 2012: 2
FWCI: 9.85
Type: journal article
Language: en
Open access: closed
Locations: The Journal of Clinical Endocrinology & Metabolism (publishedVersion)
PubMed (publishedVersion)
Funders: Pfizer
University of Chicago
U.S. Public Health Service (U54-041859)
Pfizer Pharmaceuticals
National Center for Research Resources (RR-00055)
Eunice Kennedy Shriver National Institute of Child Health and Human Development (HD-39267, R01HD039267)
Topics: Health Sciences › Medicine › Reproductive Medicine › Ovarian function and disorders
Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic and Kidney Cyst Diseases
Keywords: polycystic ovary syndrome, metabolic syndrome, adolescent girls, parental influence, paternal obesity, family transmission, maternal metabolic syndrome, androgens, insulin resistance, hyperandrogenism
MeSH terms: Adolescent, Adult, Androgens, Anthropometry, Blood Pressure, Child, Fathers, Female, Glucose Tolerance Test, Humans, Insulin Resistance, Male, Middle Aged, Obesity, Parents, Phenotype, Polycystic Ovary Syndrome, Metabolic Syndrome, Dyslipidemias, Lipid Metabolism

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Relationship of Adolescent Polycystic Ovary Syndrome to Parental Metabolic Syndrome

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks