Cited by 351Bone health and osteoporosis researchHIV-related health complications and treatmentsBody Composition Measurement Techniques

The DOI matches its Crossref record; 46 of the 46 references it cites were found in a registry or an index.

Reciprocal Relations of Subcutaneous and Visceral Fat to Bone Structure and Strength

Open access

Gilsanz, Vicente, Chalfant, James, Mo, Ashley O., Lee, David C., Dorey, Frederick J., Mittelman, Steven D.·2009·The Journal of Clinical Endocrinology & Metabolism

DOI 10.1210/jc.2008-2422PMC PMC2741723

Open this paper in CoChat — free account Open PDF

Abstract

CONTEXT: Increased body fat is a risk factor for cardiovascular and metabolic disease, yet it is uncertain whether obesity protects against osteoporosis or adiposity is harmful to bone. OBJECTIVE: The aim of the study was to assess whether the pattern of adipose tissue deposition influences bone structure and strength. DESIGN: The relations between sc and visceral adiposity and the cross-sectional dimensions and polar and principal moments of the femur in 100 healthy women ages 15 to 25 years were obtained using computed tomography. RESULTS: Multiple linear regression analyses indicated that, after adjusting for leg length and thigh musculature, both sc and visceral fat had strong and independent associations with femoral cross-sectional area, cortical bone area, principal moment maximum, principal moment minimum, and polar moment (all P values < 0.03). However, whereas sc fat had a positive predictive value with all femoral bone phenotypes, a similar but negative effect was observed between visceral fat and these measures (all P values < 0.01). CONCLUSIONS: We found that visceral and sc fat have opposite effects on the appendicular skeleton; whereas sc fat is beneficial to bone structure and strength, visceral fat serves as an unique pathogenic fat depot.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1210/jc.2008-2422

Cites

46 of 46 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

1 retracted

Body fat distribution, the menopause transition, and hormone replacement therapy.
Tchernof, A., Poehlman, É. T., & Després, J. (2000) · PubMed · Cited by 124
Retracted
Regression Diagnostics: Identifying Influential Data and Sources of Collinearity
Belsley, D. A., Kuh, E., & Welsch, R. E. (1980) · Wiley Series in Probability and Statistics · doi:10.1002/0471725153 · Cited by 7,297
RADIOGRAPHIC ATLAS OF SKELETAL DEVELOPMENT OF THE HAND AND WRIST
GREULICH, W. W., & Pyle, S. I. (1959) · The American Journal of the Medical Sciences · doi:10.1097/00000441-195909000-00030 · Cited by 5,562
Abdominal Visceral and Subcutaneous Adipose Tissue Compartments: Association With Metabolic Risk Factors in the Framingham Heart Study
Fox, C. S., Massaro, J. M., Hoffmann, U., Pou, K. M., Maurovich-Horvat, P., Liu, C.-Y., Vasan, R. S., Murabito, J. M., Meigs, J. B., Cupples, L. A., et al. (2007) · Circulation · doi:10.1161/circulationaha.106.675355 · Cited by 2,882
Increased visceral fat and decreased energy expenditure during the menopausal transition
Lovejoy, J. C., Champagne, C. M., de Jonge, L., Xie, H., & Smith, S. R. (2008) · International Journal of Obesity · doi:10.1038/ijo.2008.25 · Cited by 1,020
Mechanisms of Disease: is osteoporosis the obesity of bone?
Rosen, C. J., & Bouxsein, M. (2006) · Nature Clinical Practice Rheumatology · doi:10.1038/ncprheum0070 · Cited by 974
Visceral and Subcutaneous Adipose Tissue Volumes Are Cross-Sectionally Related to Markers of Inflammation and Oxidative Stress
Pou, K. M., Massaro, J. M., Hoffmann, U., Vasan, R. S., Maurovich‐Horvat, P., Larson, M. G., Keaney, J. F., Meigs, J. B., Lipinska, I., Kathiresan, S., et al. (2007) · Circulation · doi:10.1161/circulationaha.107.710509 · Cited by 915
Biochemical Markers of Bone Turnover, Endogenous Hormones and the Risk of Fractures in Postmenopausal Women: The OFELY Study
Garnero, P., Sornay-Rendu, E., Claustrat, B., & Delmas, P. D. (2000) · Journal of Bone and Mineral Research · doi:10.1359/jbmr.2000.15.8.1526 · Cited by 709
Relationships among body mass, its components, and bone11Published simultaneously at BoneKEy-Osteovision (http://www.bonekey-ibms.org), a Web site sponsored by the International Bone and Mineral Society.
Reid, I. R. (2002) · Bone · doi:10.1016/s8756-3282(02)00864-5 · Cited by 625
Association Between Regional Adipose Tissue Distribution and Both Type 2 Diabetes and Impaired Glucose Tolerance in Elderly Men and Women
Goodpaster, B. H., Krishnaswami, S., Resnick, H., Kelley, D. E., Haggerty, C., Harris, T. B., Schwartz, A. V., Kritchevsky, S., & Newman, A. B. (2003) · Diabetes Care · doi:10.2337/diacare.26.2.372 · Cited by 619

Flagged first, then by citations

Show all 45 references

Research works printed but not linked: 1

Belsley, 1980, Regression diagnostics, Hoboken,, NJ, Wiley

Sorted by citations

Items 101–200 of 351

Associations of Body Mass Index With Incident Fractures and Hip Structural Parameters in a Large Canadian Cohort
Shen, J., Leslie, W. D., Nielson, C. M., Majumdar, S. R., Morin, S. N., & ORWOLL, E. S. (2015) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2015-3123 · Cited by 38
Muscle mass is associated with incident fracture in postmenopausal women: The OFELY study
Sornay‐Rendu, E., Duboeuf, F., Boutroy, S., & Chapurlat, R. D. (2016) · Bone · doi:10.1016/j.bone.2016.10.024 · Cited by 38
Bone Density in the Obese Child: Clinical Considerations and Diagnostic Challenges
Kelley, J. C., Crabtree, N. J., & Zemel, B. S. (2017) · Calcified Tissue International · doi:10.1007/s00223-016-0233-4 · Cited by 38
Total and Visceral Adiposity Are Associated With Prevalent Vertebral Fracture in Women but Not Men at Age 62 Years: The Newcastle Thousand Families Study
Hind, K., Pearce, M. S., & Birrell, F. N. (2017) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.3085 · Cited by 38
Fibroblast Growth Factor 23, Mineral Metabolism, and Adiposity in Normal Kidney Function
Zaheer, S., de Boer, I. H., Allison, M., Brown, J. M., Psaty, B. M., Robinson‐Cohen, C., Michos, E. D., Ix, J. H., Kestenbaum, B. R., Siscovick, D. S., et al. (2017) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2016-3563 · Cited by 38
Cortical Bone Size Deficit in Adult Patients With Type 1 Diabetes Mellitus
Verroken, C., Pieters, W., Beddeleem, L., Goemaere, S., Zmierczak, H., Shadid, S., Kaufman, J., & Lapauw, B. (2017) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2017-00620 · Cited by 37
Visceral Fat Is a Negative Determinant of Bone Health in Obese Postmenopausal Women
Sharma, D., Anderson, P., Morris, H. A., & Clifton, P. M. (2020) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph17113996 · Cited by 41
Longitudinal relationships between whole body and central adiposity on weight-bearing bone geometry, density, and bone strength: a pQCT study in young girls
Laddu, D., Farr, J. N., Laudermilk, M., Lee, V. R., Blew, R. M., Stump, C. S., HOUTKOOPER, L. B., Lohman, T. G., & Going, S. B. (2013) · Archives of Osteoporosis · doi:10.1007/s11657-013-0156-x · Cited by 37
Effects of growth hormone administration for 6months on bone turnover and bone marrow fat in obese premenopausal women
Bredella, M. A., Gerweck, A. V., Barber, L. A., Breggia, A., Rosen, C. J., Torriani, M., & Miller, K. K. (2014) · Bone · doi:10.1016/j.bone.2014.01.022 · Cited by 36
Relationships of percent body fat and percent trunk fat with bone mineral density among Chinese, black, and white subjects
Lu, H., Fu, X., Ma, X., Wu, Z., He, W., Wang, Z., Allison, D. B., Heymsfield, S. B., & Zhu, S. (2011) · Osteoporosis International · doi:10.1007/s00198-010-1522-9 · Cited by 36
The Association Between BMI and QCT-Derived Proximal Hip Structure and Strength in Older Men: A Cross-Sectional Study
Shen, J., Nielson, C. M., Marshall, L. M., Lee, D. C., Keaveny, T. M., & ORWOLL, E. S. (2015) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.2450 · Cited by 36
Self-citation
Relative Importance of Lean Mass and Fat Mass on Bone Mineral Density in a Group of Lebanese Postmenopausal Women
Hage, R. E., Jacob, C., Moussa, E., & Baddoura, R. (2011) · Journal of Clinical Densitometry · doi:10.1016/j.jocd.2011.04.002 · Cited by 35
Exercise, Hormones, and Skeletal Adaptations During Childhood and Adolescence
Farr, J. N., Laddu, D., & Going, S. B. (2014) · Pediatric Exercise Science · doi:10.1123/pes.2014-0077 · Cited by 35
Femoral Bone Marrow Adiposity and Cortical Bone Cross‐Sectional Areas in Men With Motor Complete Spinal Cord Injury
Gorgey, A. S., Poarch, H. J., Adler, R. A., Khalil, R. E., & Gater, D. R. (2013) · PM&R · doi:10.1016/j.pmrj.2013.05.006 · Cited by 35
Body Composition and Skeletal Health: Too Heavy? Too Thin?
Faje, A. T., & Klibanski, A. (2012) · Current Osteoporosis Reports · doi:10.1007/s11914-012-0106-3 · Cited by 34
DXA surrogates for visceral fat are inversely associated with bone density measures in adolescent athletes with menstrual dysfunction
Ackerman, K. E., Davis, B., Jacoby, L., & Misra, M. (2011) · Journal of Pediatric Endocrinology and Metabolism · doi:10.1515/jpem.2011.208 · Cited by 34
Association of adiposity indices with bone density and bone turnover in the Chinese population
Wang, J., Yan, D., Hou, X., Chen, P., Sun, Q., Bao, Y., Hu, C., Zhang, Z., & Jia, W. (2017) · Osteoporosis International · doi:10.1007/s00198-017-4081-5 · Cited by 34
Advances in Osteoimmunology: Pathophysiologic Concepts and Treatment Opportunities
Rauner, M., Sipos, W., Thiele, S., & Pietschmann, P. (2012) · International Archives of Allergy and Immunology · doi:10.1159/000342426 · Cited by 34
Visceral fat measured by DXA is associated with increased risk of non-spine fractures in nonobese elderly women: a population-based prospective cohort analysis from the São Paulo Ageing & Health (SPAH) Study
Machado, L. G., Domiciano, D. S., Figueiredo, C. P., Caparbo, V. F., Takayama, L., Oliveira, R. M., Lopes, J., Menezes, P. R., & Pereira, R. M. R. (2016) · Osteoporosis International · doi:10.1007/s00198-016-3682-8 · Cited by 34
Chronic Central Administration of Ghrelin Increases Bone Mass through a Mechanism Independent of Appetite Regulation
Choi, H. J., Ki, K. H., Yang, J.-Y., Jang, B. Y., Song, J. A., Baek, W., Kim, J. H., An, J. H., Kim, S. W., Kim, S. Y., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0065505 · Cited by 33
The Skeletal Consequences of Bariatric Surgery
Krez, A. N., & Stein, E. M. (2020) · Current Osteoporosis Reports · doi:10.1007/s11914-020-00579-2 · Cited by 35
Ethnic and sex differences in bone marrow adipose tissue and bone mineral density relationship
Shen, W., Chen, J., Gantz, M., Punyanitya, M., Heymsfield, S. B., Gallagher, D., Albu, J., Engelson, E. S., Kotler, D. P., Pi-Sunyer, X., et al. (2011) · Osteoporosis International · doi:10.1007/s00198-011-1873-x · Cited by 35
Trabecular Bone Score in Obese and Nonobese Subjects With Primary Hyperparathyroidism Before and After Parathyroidectomy
Tay, D., Cusano, N. E., Rubin, M. R., Williams, J. M., Omeragic, B., & Bilezikian, J. P. (2018) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2017-02169 · Cited by 32
Fracture Risk and Bone Mineral Density in Metabolic Syndrome: A Meta-Analysis
Esposito, K., Chiodini, P., Capuano, A., Colao, A. A. L., & Giugliano, D. (2013) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2013-1775 · Cited by 31
Visceral Adipose Tissue is Negatively Associated With Bone Mineral Density in NHANES 2011-2018
Jain, R. K., & Vokes, T. (2023) · Journal of the Endocrine Society · doi:10.1210/jendso/bvad008 · Cited by 31
Abdominal adiposity, insulin and bone quality in young male rats fed a high-fat diet containing soybean or canola oil
da Costa, C. A. S., Carlos, A. S., dos Santos, A. D. S., Monteiro, A. M. V., de Moura, E. G., & do Nascimento‐Saba, C. C. A. (2011) · Clinics · doi:10.1590/s1807-59322011001000022 · Cited by 31
Association between dietary fat intake and bone mineral density in Korean adults: data from Korea National Health and Nutrition Examination Survey IV (2008∼2009)
Kwon, Y.-M., Kim, G. W., Yim, H. W., Paek, Y., & Lee, K.-S. (2014) · Osteoporosis International · doi:10.1007/s00198-014-2977-x · Cited by 30
Bone marrow fat contributes to insulin sensitivity and adiponectin secretion in premenopausal women
Ermetici, F., Briganti, S., Delnevo, A., Cannaò, P. M., Leo, G. D., Benedini, S., Terruzzi, I. M., Sardanelli, F., & Luzi, L. (2017) · Endocrine · doi:10.1007/s12020-017-1349-7 · Cited by 30
Association of Insulin Resistance with Lower Bone Volume and Strength Index of the Proximal Femur in Nondiabetic Postmenopausal Women
Yang, J. W., Hong, N., Shim, J., Rhee, Y., & Kim, H. C. (2018) · Journal of Bone Metabolism · doi:10.11005/jbm.2018.25.2.123 · Cited by 30
Sex-specific and age-specific characteristics of body composition and its effect on bone mineral density in adults in southern China: a cross-sectional study
Xiao, Z., Tan, Z., Shang, J., Cheng, Y., Tang, Y., Guo, B., Gong, J., & Xu, H. (2020) · BMJ Open · doi:10.1136/bmjopen-2019-032268 · Cited by 29
Bone Mass and Density in Youth With Type 2 Diabetes, Obesity, and Healthy Weight
Kindler, J. M., Kelly, A. T., Khoury, P. R., Katz, L. E. L., Urbina, E. M., & Zemel, B. S. (2020) · Diabetes Care · doi:10.2337/dc19-2164 · Cited by 31
Association of Regional Body Composition With Bone Mineral Density in HIV-Infected and HIV-Uninfected Women
Sharma, A., Tian, F., Yin, M. T., Keller, M. J., Cohen, M. H., & Tien, P. C. (2012) · JAIDS Journal of Acquired Immune Deficiency Syndromes · doi:10.1097/qai.0b013e31826cba6c · Cited by 29
Associations of Fat Mass and Fat Distribution With Bone Mineral Density in Chinese Obese Population
Zhang, J., Jin, Y., Xu, S., Zheng, J., Zhang, Q., Chen, J., Huang, Y., Shao, H., Yang, D., & Ying, Q. (2014) · Journal of Clinical Densitometry · doi:10.1016/j.jocd.2014.03.001 · Cited by 29
The Association Between Body Composition, 25(OH)D, and PTH and Bone Mineral Density in Black African and Asian Indian Population Groups
George, J. A., Micklesfield, L. K., Norris, S. A., & Crowther, N. J. (2014) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2013-3968 · Cited by 29
Diet, weight, cytokines and bone health in postmenopausal women
Gunn, C. A., Weber, J. L., & Kruger, M. C. (2014) · The journal of nutrition health & aging · doi:10.1007/s12603-014-0002-x · Cited by 28
Bone Response to Weight Loss Following Bariatric Surgery
Mele, C., Caputo, M., Ferrero, A., Daffara, T., Cavigiolo, B., Spadaccini, D., Nardone, A., Prodam, F., Aimaretti, G., & Marzullo, P. (2022) · Frontiers in Endocrinology · doi:10.3389/fendo.2022.921353 · Cited by 37
Association between Lean and Fat Mass and Indicators of Bone Health in Prepubertal Caucasian Children
Kâ, K., Rousseau, M., Lambert, M. A., O’Loughlin, J. L., Henderson, M., Tremblay, A., Alos, N., & Nicolau, B. F. (2013) · Hormone Research in Paediatrics · doi:10.1159/000354043 · Cited by 29
Fat and bone in children – where are we now?
Dimitri, P. (2018) · Annals of Pediatric Endocrinology & Metabolism · doi:10.6065/apem.2018.23.2.62 · Cited by 28
Effects of Exercise Training on Bone Health Parameters in Individuals With Obesity: A Systematic Review and Meta-Analysis
Zouhal, H., Berro, A. J., Kazwini, S., Saeidi, A., Jayavel, A., Clark, C. C. T., Hackney, A. C., VanDusseldorp, T. A., Abderrahman, A. B., & Hage, R. E. (2022) · Frontiers in Physiology · doi:10.3389/fphys.2021.807110 · Cited by 27
Association of visceral and subcutaneous fat with bone mineral density in US adults: a cross-sectional study
Lin, Y., Zhong, X., Lu, D., Yao, W., Zhou, J., Wu, R., & Feng, F. (2023) · Scientific Reports · doi:10.1038/s41598-023-37892-6 · Cited by 27
Fat and Bone: An Odd Couple
Kremer, R. B., & Gilsanz, V. (2016) · Frontiers in Endocrinology · doi:10.3389/fendo.2015.00190 · Cited by 29
Self-citation
The association between major depressive disorder, use of antidepressants and bone mineral density (BMD) in men.
Rauma, P. H., Pasco, J., Berk, M., Stuart, A., Koivumaa-Honkanen, H. T., Honkanen, R., Hodge, J. M., & Williams, L. J. (2015) · PubMed Central · Cited by 27
A randomized controlled trial testing an adherence-optimized Vitamin D regimen to mitigate bone change in adolescents being treated for acute lymphoblastic leukemia
Orgel, E., Mueske, N. M., Sposto, R., Gilsanz, V., Wren, T. A. L., Freyer, D. R., Butturini, A. M., & Mittelman, S. D. (2017) · Leukemia & lymphoma/Leukemia and lymphoma · doi:10.1080/10428194.2017.1289526 · Cited by 26
Self-citation
Adiposity and bone accrual—still an established paradigm?
Kawai, M., & Rosen, C. J. (2010) · Nature Reviews Endocrinology · doi:10.1038/nrendo.2009.249 · Cited by 26
Adipose tissue and volumetric bone mineral density of older Afro-Caribbean men
Yerges-Armstrong, L. M., Miljkovic, I., Cauley, J. A., Sheu, Y., Gordon, C. L., Wheeler, V. W., Bunker, C. H., Patrick, A. L., & Zmuda, J. M. (2010) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.107 · Cited by 26
Body composition assessment in the prediction of osteoporotic fractures
Hars, M., & Trombetti, A. (2017) · Current Opinion in Rheumatology · doi:10.1097/bor.0000000000000406 · Cited by 29
Musculoskeletal phenotype through the life course: the role of nutrition
Ward, K. A. (2011) · Proceedings of The Nutrition Society · doi:10.1017/s0029665111003375 · Cited by 27
Central and peripheral fat body mass have a protective effect on osteopenia or osteoporosis in adults and elderly?
Freitas, P. M. S. S., Rosa, M. L. G., Gomes, A. M., Wahrlich, V., Luca, D. G. D., Filho, R. A. D. C., Correia, D. M. D. S., Faria, C. A., & Yokoo, E. M. (2015) · Osteoporosis International · doi:10.1007/s00198-015-3414-5 · Cited by 25
The Relationship Between Greater Prepubertal Adiposity, Subsequent Age of Maturation, and Bone Strength During Adolescence
Glass, N. A., Torner, J. C., Letuchy, E. M., Burns, T. L., Janz, K. F., Gilmore, J. M. E., Schlechte, J., & Levy, S. M. (2016) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.2809 · Cited by 25
Insulin Resistance Is Associated With Smaller Cortical Bone Size in Nondiabetic Men at the Age of Peak Bone Mass
Verroken, C., Zmierczak, H., Goemaere, S., Kaufman, J., & Lapauw, B. (2016) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2016-3609 · Cited by 25
Associations Between Ethnicity, Body Composition, and Bone Mineral Density in a Southeast Asian Population
Yang, S. P., Lu, Y.-C., Khoo, C.-S., Leow, M. K., Khoo, E. Y. H., Teo, A. E. D., Lee, Y. S., De, S. D., Chong, Y. S., Gluckman, P. D., et al. (2013) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2013-2454 · Cited by 25
Anthropometric Predictors of Geometric Indices of Hip Bone Strength in a Group of Lebanese Postmenopausal Women
Hage, R. E., & Baddoura, R. (2012) · Journal of Clinical Densitometry · doi:10.1016/j.jocd.2011.11.003 · Cited by 25
Role of Adipose Tissue in Metabolic System Disorders
Rezaee, F. (2013) · Journal of Diabetes & Metabolism · doi:10.4172/2155-6156.s13-008 · Cited by 30
Anorexia nervosa, obesity and bone metabolism.
Misra, M., & Klibanski, A. (2013) · PubMed · Cited by 24
Fat, adipokines, bone structure and bone regulatory factors associations in obesity
Vilaça, T., Evans, A. L., Gossiel, F., Paggiosi, M., Eastell, R., & Walsh, J. (2022) · European Journal of Endocrinology · doi:10.1530/eje-22-0530 · Cited by 24
Dairy product intake decreases bone resorption following a 12-week diet and exercise intervention in overweight and obese adolescent girls
Josse, A. R., Ludwa, I. A., Kouvelioti, R., Calleja, M., Falk, B., Ward, W. E., & Klentrou, P. (2020) · Pediatric Research · doi:10.1038/s41390-020-0834-5 · Cited by 24
Relationships between Obesity and Incidence of Fractures in a Middle‐Aged Population: A Study from the CARTaGENE Cohort
Turcotte, A., Jean, S., Morin, S. N., Mac‐Way, F., & Gagnon, C. (2023) · JBMR Plus · doi:10.1002/jbm4.10730 · Cited by 23
Distinct Relationships of Intramuscular and Subcutaneous Fat With Cortical Bone: Findings From a Cross-Sectional Study of Young Adult Males and Females
Deere, K. C., Sayers, A. E., Viljakainen, H. T., Lawlor, D. A., Sattar, N. A., Kemp, J. P., Fraser, W. D., & Tobias, J. H. (2013) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2013-1272 · Cited by 23
The relationship between body fat and bone mineral density in Korean men and women
Kim, W. D., Chung, S. G., Kim, K., Seo, H. G., Oh, B., Yi, Y., & Kim, M. J. (2013) · Journal of Bone and Mineral Metabolism · doi:10.1007/s00774-013-0545-7 · Cited by 23
Update on Body Composition and Bone Density in Children with Prader-Willi Syndrome
Rubin, D. A., Sokoloff, N. C., Castner, D. M., Judelson, D. A., Wright, P., Duran, A. T., & Haqq, A. M. (2013) · Hormone Research in Paediatrics · doi:10.1159/000350525 · Cited by 23
Associação entre o índice de massa corporal e osteoporose em mulheres da região noroeste do Rio Grande do Sul
Mazocco, L., & Chagas, P. (2016) · Revista Brasileira de Reumatologia · doi:10.1016/j.rbr.2016.07.009 · Cited by 22
Obesity, bariatric surgery, and bone
Soleymani, T., Tejavanija, S., & Morgan, S. (2011) · Current Opinion in Rheumatology · doi:10.1097/bor.0b013e328346f832 · Cited by 22
Correlation of obesity and osteoporosis: Effect of free fatty acids on bone marrow-derived mesenchymal stem cell differentiation
Lv, S., WU, L., CHENG, P., Yu, J., Zhang, A., Zha, J., LIU, J., Wang, L., Di, W., Hu, M., et al. (2010) · Experimental and Therapeutic Medicine · doi:10.3892/etm_00000095 · Cited by 21
Body composition predictors of skeletal integrity in obesity
Haines, M. S., Dichtel, L. E., Gerweck, A. V., Torriani, M., Miller, K. K., & Bredella, M. A. (2016) · Skeletal Radiology · doi:10.1007/s00256-016-2363-1 · Cited by 21
Bone Variables in Active Overweight/Obese Men and Sedentary Overweight/Obese Men
Khoury, G. E., Zouhal, H., Cabagno, G., Khoury, C. E., Rizkallah, M., Maalouf, G., & Hage, R. E. (2016) · Journal of Clinical Densitometry · doi:10.1016/j.jocd.2016.10.009 · Cited by 21
Does Visceral or Subcutaneous Fat Influence Peripheral Cortical Bone Strength During Adolescence? A Longitudinal Study
Glass, N. A., Torner, J. C., Letuchy, E. M., Burns, T. L., Janz, K. F., Gilmore, J. M. E., Schlechte, J., & Levy, S. M. (2017) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.3325 · Cited by 20
Adiposity reduces the risk of osteoporosis in Chinese rural population: the Henan rural cohort study
Tian, H., Pan, J., Qiao, D., Dong, X., Li, R., Wang, Y., Tu, R., Abdulai, T., Liu, X., Hou, J., et al. (2020) · BMC Public Health · doi:10.1186/s12889-020-8379-4 · Cited by 20
Bone Characteristics and Their Determinants in Adolescents and Young Adults with Early-Onset Severe Obesity
Viljakainen, H. T., Valta, H., Lipsanen‐Nyman, M., Saukkonen, T. T., Kajantie, E., Andersson, S., & Mäkitie, O. (2015) · Calcified Tissue International · doi:10.1007/s00223-015-0031-4 · Cited by 20
Is waist circumference a negative predictor of calcaneal bone mineral density in adult Chinese men with normal weight?
Ling, C., Liang, J., Wen, J., Huang, H., Li, L., Lin, W., Zong, L., Wang, N., Cai, L., Tang, K., et al. (2019) · Annals of Translational Medicine · doi:10.21037/atm.2019.04.71 · Cited by 19
Differential Effects of Dietary Fat Content and Protein Source on Bone Phenotype and Fatty Acid Oxidation in Female C57Bl/6 Mice
Sawin, E. A., Stroup, B. M., Murali, S. G., O’Neill, L. M., Ntambi, J. M., & Ney, D. M. (2016) · PLoS ONE · doi:10.1371/journal.pone.0163234 · Cited by 19
Does Muscular Power Predict Bone Mineral Density in Young Adults?
Khawaja, A., Sabbagh, P., Prioux, J., Zunquin, G., Baquet, G., Maalouf, G., & Hage, R. E. (2019) · Journal of Clinical Densitometry · doi:10.1016/j.jocd.2019.01.005 · Cited by 19
Fat as a Friend or Foe of the Bone
Gruneisen, E., Kremer, R. B., & Duque, G. (2024) · Current Osteoporosis Reports · doi:10.1007/s11914-024-00864-4 · Cited by 20
The relationship between adiposity, bone density and microarchitecture is maintained in young women irrespective of diabetes status
Abdalrahaman, N., McComb, C., Foster, J. E., Lindsay, R. S., Drummond, R. S., McKay, G. A., Perry, C. G., & Ahmed, S. F. (2017) · Clinical Endocrinology · doi:10.1111/cen.13410 · Cited by 18
Bone mineral density saturation as influenced by the visceral adiposity index in adults older than 20 years: a population-based study
Chen, Z.-H., Zhou, T., Bu, Y., & Yang, L. (2023) · Lipids in Health and Disease · doi:10.1186/s12944-023-01931-y · Cited by 17
Estimation of Trochanteric Soft Tissue Thickness From Dual-Energy X-ray Absorptiometry
Schacter, I., & Leslie, W. D. (2013) · Journal of Clinical Densitometry · doi:10.1016/j.jocd.2013.01.007 · Cited by 17
Reduction of visceral fat could be related to the improvement of TBS in diabetes mellitus
Moon, H. U., Lee, N., Chung, Y., & Choi, Y. J. (2020) · Journal of Bone and Mineral Metabolism · doi:10.1007/s00774-020-01107-z · Cited by 17
Relationship between body composition and bone mineral density in postmenopausal women with type 2 diabetes mellitus
Gao, L., Ping, Z., Wang, Y., Zhang, W., Zhao, J. H., Liu, Y., Liu, J., & He, S. (2022) · BMC Musculoskeletal Disorders · doi:10.1186/s12891-022-05814-8 · Cited by 17
Percent fat mass is inversely associated with bone mass and hip geometry in rural Chinese adolescents
Hong, X., Arguelles, L., Liu, X., Tsai, H., Hsu, Y., Wang, B., Zhang, S., Li, Z., Tang, G., Liu, X., et al. (2010) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.40 · Cited by 17
Effects of a Randomized Weight Loss Intervention Trial in Obese Adolescents on Tibia and Radius Bone Geometry and Volumetric Density
Kelley, J. C., Stettler-Davis, N., Leonard, M. B., Hill, D. L., Wrotniak, B. H., Justine Shults, A., Stallings, V. A., Berkowitz, R. I., Xanthopoulos, M. S., Prout, E. P., et al. (2017) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.3288 · Cited by 17
Perspective: the bone-fat connection
Bredella, M. A. (2010) · Skeletal Radiology · doi:10.1007/s00256-010-0936-y · Cited by 17
Visceral fat metabolic activity evaluated by 18F-FDG PET/CT is associated with osteoporosis in healthy postmenopausal Korean women
Pahk, K., Kwon, Y., Kim, M.-K., Park, S. S., & Kim, S. (2020) · Obesity Research & Clinical Practice · doi:10.1016/j.orcp.2020.05.008 · Cited by 16
Increased Glycemic Variability Evaluated by Continuous Glucose Monitoring is Associated with Osteoporosis in Type 2 Diabetic Patients
Huang, R., Wang, H., Shen, Z., Cai, T., Zhou, Y., Wang, Y., Xia, W., Ding, B., Yan, R., Li, H., et al. (2022) · Frontiers in Endocrinology · doi:10.3389/fendo.2022.861131 · Cited by 16
Osteoporosis: From Bone Biology to Individual Treatment Decision
Gonçalves, M. J., Rodrigues, A. M., Canhão, H. M., & Fonseca, J. E. (2013) · Acta Médica Portuguesa · doi:10.20344/amp.4271 · Cited by 16
Obesity and its relationship with falls, fracture site and bone mineral density in postmenopausal women
3rd Orthopaedic Department, K. G. H., & Sotiriadi-Vlachou, S. (2017) · Journal of Frailty, Sarcopenia and Falls · doi:10.22540/jfsf-02-028 · Cited by 16
The association between paraspinal muscle parameters and vertebral pedicle microstructure in patients undergoing lumbar fusion surgery
Muellner, M., Chiapparelli, E. A., Haffer, H. P. H., Dodo, Y., Salzmann, S. N., Amini, D. A., Moser, M., Zhu, J., Carrino, J. A., Tan, E. T., et al. (2022) · International Orthopaedics · doi:10.1007/s00264-022-05659-9 · Cited by 15
Impact of Age, Anthropometric Data and Body Composition on Calcaneal Bone Characteristics, as Measured by Quantitative Ultrasound (QUS) in an Older German Population
Brunner, C., Pons‐Kühnemann, J., & Neuhäuser‐Berthold, M. (2011) · Ultrasound in Medicine & Biology · doi:10.1016/j.ultrasmedbio.2011.09.015 · Cited by 15
Relation Between Serum Osteocalcin Levels and Body Composition in Obese Children
Wang, J., Tang, Q., Ruan, H., & Cai, W. (2013) · Journal of Pediatric Gastroenterology and Nutrition · doi:10.1097/mpg.0000000000000243 · Cited by 15
Muscle density predicts changes in bone density and strength: a prospective study in girls.
Laddu, D., Farr, J. N., Lee, V. R., Blew, R. M., Stump, C. S., HOUTKOOPER, L. B., Lohman, T. G., & Going, S. B. (2014) · PubMed · Cited by 15
Inducible Models of Bone Loss
Doucette, C. R., & Rosen, C. J. (2014) · Current Protocols in Mouse Biology · doi:10.1002/9780470942390.mo140071 · Cited by 16
Exploring the Interplay between Vitamin D, Insulin Resistance, Obesity and Skeletal Health
Abed, M. N., Alassaf, F. A., & Qazzaz, M. E. (2024) · Journal of Bone Metabolism · doi:10.11005/jbm.2024.31.2.75 · Cited by 14
The role of PPARγ in childhood obesity-induced fractures
McCann, M. R., & Ratneswaran, A. (2019) · Genes & Nutrition · doi:10.1186/s12263-019-0653-7 · Cited by 14
Obesity, vitamin D status and physical activity: 1,25(OH)2D as a potential marker of vitamin D deficiency in obese subjects
Valentini, A., Perrone, M. A., Cianfarani, M. A., Tarantino, U., Massoud, R., Merra, G., Bernardini, S., Morris, H. A., & Bertoli, A. (2020) · Panminerva Medica · doi:10.23736/s0031-0808.20.03770-2 · Cited by 13
In premenopausal women with idiopathic osteoporosis, lower bone formation rate is associated with higher body fat and higher IGF-1
Goetz, T. G., Nair, N., Shiau, S., Recker, R. R., Lappe, J. M., Dempster, D. W., Zhou, H., Zhao, B., Guo, X.-D. E., Shen, W., et al. (2021) · Osteoporosis International · doi:10.1007/s00198-021-06196-8 · Cited by 13
Ischemic heart disease is associated with vertebral fractures in patients with type 2 diabetes mellitus
Muñoz‐Torres, M., Reyes‐García, R., García‐Martin, A., Jiménez‐Moleón, J. J., Ramírez, A. R. G., Lara-Villoslada, M. J., & Moreno, P. R. (2013) · Journal of Diabetes Investigation · doi:10.1111/jdi.12034 · Cited by 13
The impact of obesity on bone health: molecular pathways, metabolic interactions, and associated pathologies
Bagherifard, A., Hemmatyar, A., Khosravi, K., Rouzbahani, A., Mokhtari, K., Yahyazedeh, H., & Tanzadehpanah, H. (2025) · International Journal of Obesity · doi:10.1038/s41366-025-01907-1 · Cited by 16
Sarcopenia negatively affects hip structure analysis variables in a group of Lebanese postmenopausal women
Saddik, H., Nasr, R., Pinti, A., Watelain, É., Fayad, I., Baddoura, R., Berro, A.-J., Rassy, N., Lespessailles, É., Toumi, H., et al. (2020) · BMC Bioinformatics · doi:10.1186/s12859-020-3353-9 · Cited by 11
Sarcopenic obesity defined by visceral adiposity was associated with osteoporotic vertebral fracture
Chen, H., Yi, Y., Zhang, S., Xu, H.-W., Fang, X., Tao-Hu, Wu, D., & Wang, S. (2022) · Archives of Osteoporosis · doi:10.1007/s11657-022-01087-9 · Cited by 12
The impact of obesity on bone health: an overview
Mendonça, F. M., Soares, R. A., Carvalho, D. M., & Freitas, P. (2022) · Endokrynologia Polska · doi:10.5603/ep.a2022.0063 · Cited by 14
Geometric Indices of Hip Bone Strength in Overweight and Control Elderly Men
Hage, R. E., Theunynck, D., & Rocher, E. (2014) · Lebanese Medical Journal · doi:10.12816/0006216 · Cited by 12
Epicardial fat is a negative predictor of spine volumetric bone mineral density and trabecular bone score in acromegaly
Valassi, E., Crespo, I., Malouf, J., Viladés, D., Leta, R., Llauger, J., Urgell, E., Aulinas, A., Marín, A. M., Biagetti, B., et al. (2016) · Endocrine · doi:10.1007/s12020-016-0945-2 · Cited by 12

Authors: Gilsanz, V., Chalfant, J., Mo, A. O., Lee, D. C., Dorey, F. J., & Mittelman, S. D.
Affiliations: University of Southern California (US)
Corresponding author: Gilsanz, Vicente
ORCID: Gilsanz, Vicente
Chalfant, James
Lee, David C.
Mittelman, Steven D.
Venue: The Journal of Clinical Endocrinology & Metabolism
Publisher: The Endocrine Society
Published: 2009-09-01
Volume: 94
Issue: 9
Pages: 3387-3393
ISSN: 0021-972X (ISSN-L)
1945-7197
DOI: 10.1210/jc.2008-2422
PMC: PMC2741723
OpenAlex: W1971193583
Cited by: 351
References: 45
Citations by year: 2026: 5 · 2025: 12 · 2024: 18 · 2023: 19 · 2022: 23 · 2021: 14 · 2020: 23 · 2019: 13 · 2018: 17 · 2017: 29 · 2016: 26 · 2015: 17 · 2014: 30 · 2013: 37 · 2012: 23
FWCI: 23.82
Type: journal article
Language: en
Open access: bronze
doi.org
Locations: The Journal of Clinical Endocrinology & Metabolism (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
Funders: National Institute of Arthritis and Musculoskeletal and Skin Diseases (R01AR052744)
Topics: Health Sciences › Medicine › Orthopedics and Sports Medicine › Bone health and osteoporosis research
Health Sciences › Medicine › Infectious Diseases › HIV-related health complications and treatments
Health Sciences › Medicine › Physiology (medical) › Body Composition Measurement Techniques
Keywords: subcutaneous adipose tissue, visceral fat, body fat distribution, bone structure, bone strength, femur, cortical bone area, cross-sectional area, young women, osteoporosis risk
MeSH terms: Adolescent, Adult, Bone and Bones, Female, Humans, Tomography, X-Ray Computed, Linear Models, Subcutaneous Fat, Intra-Abdominal Fat

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Reciprocal Relations of Subcutaneous and Visceral Fat to Bone Structure and Strength

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks