Cited by 232Stress Responses and CortisolTreatment of Major DepressionPituitary Gland Disorders and Treatments

The DOI matches its Crossref record; 9 of the 9 references it cites were found in a registry or an index.

Pituitary Size in Depression*

KRISHNAN, K. RANGA RAMA, DORAISWAMY, P. MURALI, LURIE, SCOTT N., FIGIEL, GARY S., HUSAIN, MUSTAFA M., BOYKO, OREST B., ELLINWOOD, EVERETT H., NEMEROFF, CHARLES B.·1991·The Journal of Clinical Endocrinology & Metabolism

DOI 10.1210/jcem-72-2-256

Open this paper in CoChat — free account

Abstract

Magnetic resonance images centered at the pituitary stalk were used to measure pituitary gland size in 19 patients with major depression compared with that in age- and sex-matched controls. Depressed patients had significantly greater pituitary cross-sectional area (P = 0.0009) and volume (P = 0.007) than the controls. This difference was particularly prominent in elderly depressed patients compared to elderly controls. These results provide the first demonstration of structural alterations in the pituitary gland in major depression.

Integrity signals

Registry

Crossref · 10.1210/jcem-72-2-256

Cites

9 of 9 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

A Specific Laboratory Test for the Diagnosis of Melancholia: Standardization, Validation, and Clinical Utility
Carroll, B. J. (1981) · Archives of General Psychiatry · doi:10.1001/archpsyc.1981.01780260017001 · Cited by 2,243
Elevated Concentrations of CSF Corticotropin-Releasing Factor-Like Immunoreactivity in Depressed Patients
Nemeroff, C. B., Widerlöv, E., Bissette, G., Walléus, H., Karlsson, I., Eklund, K., Kilts, C. D., Loosen, P. T., & Vale, W. (1984) · Science · doi:10.1126/science.6334362 · Cited by 1,485
Self-citation
Psychiatric implications of basic and clinical studies with corticotropin-releasing factor.
Gold, P., Chrousos, G., Kellner, C., Post, R., Roy, A., Augerinos, P., Schulte, H., Oldfield, E., & Loriaux, D. (1984) · American Journal of Psychiatry · doi:10.1176/ajp.141.5.619 · Cited by 460
Development and aging of brain midline structures: assessment with MR imaging.
Hayakawa, K., Konishi, Y., MATSUDA, T., Kuriyama, M., Konishi, K., Yamashita, K., Okumura, R., & Hamanaka, D. (1989) · Radiology · doi:10.1148/radiology.172.1.2740500 · Cited by 168
Quantification of Morphological Changes in Pituitary Corticotropes Produced byin VivoCorticotropin-Releasing Factor Stimulation and Adrenalectomy*
Westlund, K. N., Aguilera, G., & Childs, G. V. (1985) · Endocrinology · doi:10.1210/endo-116-1-439 · Cited by 99
Blunting of ACTH response to human CRH in depressed patients is avoided by metyrapone pretreatment
von Bardeleben, U., Stalla, G. K., Müller, O. A., & Holsboer, F. (1988) · Biological Psychiatry · doi:10.1016/0006-3223(88)90254-5 · Cited by 81
Augmented Pituitary Corticotropin Response to a Threshold Dosage of Human Corticotropin-Releasing Hormone in Depressives Pretreated With Metyrapone
Lisansky, J. (1989) · Archives of General Psychiatry · doi:10.1001/archpsyc.1989.01810070067011 · Cited by 72
A brain magnetic resonance imaging study of pituitary gland morphology in anorexia nervosa and bulimia
Doraiswamy, P. M., Krishnan, K. R. R., Figiel, G. S., Husain, M. M., Boyko, O. B., Rockwell, W. J. K., & Ellinwood, E. H. (1990) · Biological Psychiatry · doi:10.1016/0006-3223(90)90628-f · Cited by 68
Self-citation
Magnetic Resonance Imaging of Pituitary and Parasellar Abnormalities
Chakeres, D. W., Curtin, A., & Ford, G. (1989) · Radiologic Clinics of North America · doi:10.1016/s0033-8389(22)00875-2 · Cited by 65

Show all 9 references

Sorted by citations

Brain structural and functional abnormalities in mood disorders: implications for neurocircuitry models of depression
Drevets, W. C., Price, J. L., & Furey, M. L. (2008) · Brain Structure and Function · doi:10.1007/s00429-008-0189-x · Cited by 2,241
“For example Krishnan et al. (1991) showed that MRI-based measures of cross-sectional area and volume of the pituitary were increased (by 34 and 41%, respectively) in depressives versus controls.”
BackgroundResult
Neurocircuitry of Mood Disorders
Price, J. L., & Drevets, W. C. (2010) · Neuropsychopharmacology · doi:10.1038/npp.2009.104 · Cited by 1,606
The role of corticotropin-releasing factor in depression and anxiety disorders
Arborelius, L., Owens, M., Plotsky, P., & Nemeroff, C. (1999) · Journal of Endocrinology · doi:10.1677/joe.0.1600001 · Cited by 1,378
Self-citation
Neuroimaging studies of mood disorders
Drevets, W. C. (2000) · Biological Psychiatry · doi:10.1016/s0006-3223(00)01020-9 · Cited by 1,334
The stress system in the human brain in depression and neurodegeneration
Swaab, D. F., Bao, A.-M., & Lucassen, P. J. (2005) · Ageing Research Reviews · doi:10.1016/j.arr.2005.03.003 · Cited by 984
The anatomy of mood disorders—review of structural neuroimaging studies
Soares, J. C., & Mann, J. J. (1997) · Biological Psychiatry · doi:10.1016/s0006-3223(96)00006-6 · Cited by 760
PSYCHONEUROENDOCRINOLOGY OF DEPRESSION
Plotsky, P. M., Owens, M. J., & Nemeroff, C. B. (1998) · Psychiatric Clinics of North America · doi:10.1016/s0193-953x(05)70006-x · Cited by 672
Self-citation
The stress system in depression and neurodegeneration: Focus on the human hypothalamus
Bao, A., Meynen, G., & Swaab, D. F. (2007) · Brain Research Reviews · doi:10.1016/j.brainresrev.2007.04.005 · Cited by 565
Depression in Patients With Cancer
McDaniel, J. S. (1995) · Archives of General Psychiatry · doi:10.1001/archpsyc.1995.03950140007002 · Cited by 541
The impact of early adverse experiences on brain systems involved in the pathophysiology of anxiety and affective disorders
Heim, C., & Nemeroff, C. B. (1999) · Biological Psychiatry · doi:10.1016/s0006-3223(99)00224-3 · Cited by 502
Self-citation
Magnetic resonance imaging studies in unipolar depression: Systematic review and meta-regression analyses
Arnone, D., McIntosh, A. M., Ebmeier, K. P., Munafò, M. R., & Anderson, I. M. (2012) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2011.05.003 · Cited by 495
Chronic pain, chronic stress and depression: Coincidence or consequence?
Blackburn‐Munro, G., & Blackburn‐Munro, R. E. (2001) · Journal of Neuroendocrinology · doi:10.1046/j.0007-1331.2001.00727.x · Cited by 493
Glucose metabolism in the amygdala in depression: relationship to diagnostic subtype and plasma cortisol levels
Drevets, W. C., Price, J. L., Bardgett, M. E., Reich, T., Todd, R. D., & Raichle, M. E. (2002) · Pharmacology Biochemistry and Behavior · doi:10.1016/s0091-3057(01)00687-6 · Cited by 457
Structural neuroimaging and mood disorders: Recent findings, implications for classification, and future directions
Steffens, D. C., & Krishnan, K. (1998) · Biological Psychiatry · doi:10.1016/s0006-3223(98)00084-5 · Cited by 392
Self-citation
Can stress cause depression?
van Praag, H. M. (2004) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2004.05.031 · Cited by 398
The neuroendocrinology of depression and chronic stress
Checkley, S. A. (1996) · British Medical Bulletin · doi:10.1093/oxfordjournals.bmb.a011570 · Cited by 323
Pathophysiology of hypercortisolism in depression
Carroll, B. J., Cassidy, F., Naftolowitz, D., Tatham, N. E., Wilson, W. H., Iranmanesh, A., Liu, P. Y., & Veldhuis, J. D. (2007) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.2007.00967.x · Cited by 317
Pituitary volumes in pediatric maltreatment-related posttraumatic stress disorder
Thomas, L. A., & Bellis, M. D. D. (2004) · Biological Psychiatry · doi:10.1016/j.biopsych.2003.11.021 · Cited by 267
The Hypothalamic-Pituitary-Adrenal Axis in Major Depressive Disorder
Varghese, F. P., & Brown, E. S. (2001) · The Primary Care Companion For CNS Disorders · doi:10.4088/pcc.v03n0401 · Cited by 245
Volumetric brain imaging findings in mood disorders
Beyer, J. L., & Krishnan, K. (2002) · Bipolar Disorders · doi:10.1034/j.1399-5618.2002.01157.x · Cited by 234
Self-citation
MRI findings in patients with affective disorder: a meta‐analysis
Videbech, P. (1997) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.1997.tb10146.x · Cited by 226
The effects of neonatal stress on brain development: implications for psychopathology
GRAHAM, Y. P., HEIM, C., GOODMAN, S. H., MILLER, A. H., & NEMEROFF, C. B. (1999) · Development and Psychopathology · doi:10.1017/s0954579499002205 · Cited by 197
Self-citation
The potential role of excessive cortisol induced by HPA hyperfunction in the pathogenesis of depression
Stokes, P. E. (1995) · European Neuropsychopharmacology · doi:10.1016/0924-977x(95)00039-r · Cited by 188
Invited review: the evolution of antidepressant mechanisms
Slattery, D. A., Hudson, A. L., & Nutt, D. (2004) · Fundamental and Clinical Pharmacology · doi:10.1111/j.1472-8206.2004.00195.x · Cited by 185
Can stress cause depression?
van Praag, H. M. (2005) · The World Journal of Biological Psychiatry · doi:10.1080/15622970510030018 · Cited by 189
Risk Factors for Development of Depression and Psychosis
Pariante, C. M. (2009) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2009.04978.x · Cited by 186
The Role of Corticotropin‐Releasing Factor in the Pathophysiology of Affective and Anxiety Disorders: Laboratory and Clinical Studies
Owens, M. J., & Nemeroff, C. B. (2007) · Novartis Foundation symposium · doi:10.1002/9780470514368.ch15 · Cited by 181
Self-citation
Pituitary volume in psychosis
Pariante, C. M., Vassilopoulou, K., Velakoulis, D., Phillips, L., Soulsby, B., Wood, S. J., Brewer, W., Smith, D., Dazzan, P., Yung, A. R., et al. (2004) · British Journal of Psychiatry · doi:10.1192/bjp.185.1.5 · Cited by 180
Elevated neuron number in the limbic thalamus in major depression
Young, K. A., Holcomb, L. A., Yazdani, U., Hicks, P. B., & German, D. C. (2004) · American Journal of Psychiatry · doi:10.1176/appi.ajp.161.7.1270 · Cited by 169
Mood and neuropsychological function in depression: the role of corticosteroids and serotonin
McAllister-Williams, H., Ferrier, I. N., & Young, A. H. (1998) · Psychological Medicine · doi:10.1017/s0033291798006680 · Cited by 165
Assessment and treatment of depression in the cancer patient
Newport, D. J., & Nemeroff, C. B. (1998) · Journal of Psychosomatic Research · doi:10.1016/s0022-3999(98)00011-7 · Cited by 167
Self-citation
The hypothalamic-pituitary-adrenal axis and serotonin abnormalities: a selective overview for the implications of suicide prevention
Pompili, M., Serafini, G., Innamorati, M., Möller-Leimkühler, A. M., Giupponi, G., Girardi, P., Tatarelli, R., & Lester, D. (2010) · European Archives of Psychiatry and Clinical Neuroscience · doi:10.1007/s00406-010-0108-z · Cited by 164
Chapter 21 The role of corticotropin-releasing hormone in the pathogenesis of Cushing's disease, anorexia nervosa, alcoholism, affective disorders and dementia
Holsboer, F., Spengler, D., & Heuser, I. (1992) · Progress in brain research · doi:10.1016/s0079-6123(08)64586-0 · Cited by 159
Depression and Endocrine Disorders: Focus on the Thyroid and Adrenal System
Musselman, D. L., & Nemeroff, C. B. (1996) · The British Journal of Psychiatry · doi:10.1192/s0007125000298504 · Cited by 156
Self-citation
Increased Pituitary Volume in Antipsychotic-Free and Antipsychotic-Treated Patients of the Æsop First-Onset Psychosis Study
Pariante, C. M., Dazzan, P., Danese, A., Morgan, K. D., Brudaglio, F., Morgan, C., Fearon, P., Orr, K., Hutchinson, G., Pantelis, C., et al. (2005) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300766 · Cited by 152
In vivo assessment of pituitary volume with magnetic resonance imaging and systematic stereology: Relationship to dexamethasone suppression test results in patients
Axelson, D., Doraiswamy, P. M., Boyko, O. B., Escalona, P. R., McDonald, W. M., Ritchie, J., Patterson, L. J., Ellinwood, E. H., Nemeroff, C. B., & Krishnan, K. (1992) · Psychiatry Research · doi:10.1016/0165-1781(92)90070-j · Cited by 147
Self-citation
Atypical Antipsychotics and Pituitary Tumors: A Pharmacovigilance Study
Szarfman, A., Tonning, J. M., Levine, J. G., & Doraiswamy, P. M. (2006) · Pharmacotherapy The Journal of Human Pharmacology and Drug Therapy · doi:10.1592/phco.26.6.748 · Cited by 144
Self-citation
The neuropsychology of mood disorders
Chamberlain, S. R., & Sahakian, B. J. (2006) · Current Psychiatry Reports · doi:10.1007/s11920-006-0051-x · Cited by 140
Decreased pituitary volume in patients with bipolar disorder
Sassi, R. B., Nicoletti, M., Brambilla, P., Harenski, K. A., Mallinger, A. G., Frank, E., Kupfer, D. J., Keshavan, M. S., & Soares, J. C. (2001) · Biological Psychiatry · doi:10.1016/s0006-3223(01)01086-1 · Cited by 135
Brain Systems Underlying Susceptibility to Helplessness and Depression
Shumake, J., & Gonzalez-Lima, F. (2003) · Behavioral and Cognitive Neuroscience Reviews · doi:10.1177/1534582303259057 · Cited by 139
Brain-immune interactions and disease susceptibility
Marques-Deak, A., Cizza, G., & Sternberg, E. M. (2005) · Molecular Psychiatry · doi:10.1038/sj.mp.4001643 · Cited by 134
Brain Structural Effects of Antidepressant Treatment in Major Depression
Dusi, N., Barlati, S., Vita, A., & Brambilla, P. (2015) · Current Neuropharmacology · doi:10.2174/1570159x1304150831121909 · Cited by 140
The role of Corticotropin Releasing Factor in Depressive Illness: a Critical Review
Mitchell, A. J. (1998) · Neuroscience & Biobehavioral Reviews · doi:10.1016/s0149-7634(97)00059-6 · Cited by 115
Endocrine disturbances in depression
Tichomirowa, M. A., Keck, M. E., Schneider, H. J., Páez-Pereda, M., Renner, U., Holsboer, F., & Stalla, G. K. (2005) · Journal of Endocrinological Investigation · doi:10.1007/bf03345535 · Cited by 111
Anatomical MRI findings in mood and anxiety disorders
Brambilla, P., Barale, F., Caverzasi, E., & Soares, J. C. (2002) · Epidemiologia e Psichiatria Sociale · doi:10.1017/s1121189x00005558 · Cited by 104
Normal development of the pituitary gland: assessment with three-dimensional MR volumetry.
Takano, K., Utsunomiya, H., Ono, H., Ohfu, M., & Okazaki, M. (1999) · PubMed Central · Cited by 103
The Neuroendocrinology of Mood Disorders
Rubín, R. T., & Carroll, B. J. (2009) · Elsevier eBooks · doi:10.1016/b978-008088783-8.00092-9 · Cited by 104
HPA Axis Interactions with Behavioral Systems
Packard, A. E. B., Egan, A. E., & Ulrich‐Lai, Y. M. (2016) · Comprehensive physiology · doi:10.1002/cphy.c150042 · Cited by 138
MR assessment of pituitary gland morphology in healthy volunteers: age- and gender-related differences.
Doraiswamy, P. M., Potts, J., Axelson, D., Husain, M. M., Lurie, S. N., Na, C., Escalona, P. R., McDonald, W. M., Figiel, G. S., & Ellinwood, E. H. (1992) · PubMed Central · Cited by 99
Self-citation
The Association between Regular Cannabis Exposure and Alterations of Human Brain Morphology: An Updated Review of the Literature
Lorenzetti, V., Solowij, N., Fornito, A., Lubman, D. I., & Yücel, M. (2014) · Current Pharmaceutical Design · doi:10.2174/13816128113199990435 · Cited by 99
Basal Hypothalamo-Pituitary-Adrenal Axis Activity and Corticotropin Feedback in Young and Older Men: Relationships to Magnetic Resonance Imaging-Derived Hippocampus and Cingulate Gyrus Volumes
Wolf, O. T., Convit, A. J., de Leon, M. J., Caraos, C., & Qadri, S. F. (2002) · Neuroendocrinology · doi:10.1159/000054715 · Cited by 95
Changes in the immune system in depression and dementia: causal or co‐incidental effects?
Leonard, B. E. (2001) · International Journal of Developmental Neuroscience · doi:10.1016/s0736-5748(01)00014-4 · Cited by 91
Corticotropin-releasing hormone and the hypothalamic–pituitary–adrenal axis in psychiatric disease
Naughton, M., Dinan, T. G., & Scott, L. V. (2014) · Handbook of clinical neurology · doi:10.1016/b978-0-444-59602-4.00005-8 · Cited by 97
Adrenal Size Is Increased in Multiple Sclerosis
Reder, A. T., Makowiec, R. L., & Lowy, M. T. (1994) · Archives of Neurology · doi:10.1001/archneur.1994.00540140057015 · Cited by 89
Structural Changes in the Brain in Depression and Relationship to Symptom Recurrence
Bremner, J. D. (2002) · CNS Spectrums · doi:10.1017/s1092852900017442 · Cited by 89
MRI study of the pituitary gland in adolescent depression
MacMaster, F. P., & Kusumakar, V. (2004) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2003.11.001 · Cited by 85
Interaction of prefrontal cortical and hypothalamic systems in the pathogenesis of depression
Swaab, D. F., Fliers, E., Hoogendijk, W. J. G., Veltman, D. J., & Zhou, J. (2000) · Progress in brain research · doi:10.1016/s0079-6123(00)26025-1 · Cited by 81
PITUITARY INCIDENTALOMAS
Molitch, M. E. (1997) · Endocrinology and Metabolism Clinics of North America · doi:10.1016/s0889-8529(05)70279-6 · Cited by 81
Vasopressin as a target for antidepressant development: an assessment of the available evidence
Scott, L. V., & Dinan, T. G. (2002) · Journal of Affective Disorders · doi:10.1016/s0165-0327(02)00026-5 · Cited by 78
An MRI study of pituitary volume and parasuicidal behavior in teenagers with first-presentation borderline personality disorder
Jovev, M., Garner, B., Phillips, L., Velakoulis, D., Wood, S. J., Jackson, H. J., Pantelis, C., McGorry, P. D., & Chanen, A. M. (2008) · Psychiatry Research Neuroimaging · doi:10.1016/j.pscychresns.2007.12.003 · Cited by 76
Pituitary volume in psychosis: the first review of the evidence
Pariante, C. M. (2008) · Journal of Psychopharmacology · doi:10.1177/0269881107084020 · Cited by 73
Neuroplasticity in mood disorders
Drevets, W. C. (2004) · Dialogues in Clinical Neuroscience · doi:10.31887/dcns.2004.6.2/wdrevets · Cited by 75
Pituitary volume in unaffected relatives of patients with schizophrenia and bipolar disorder
Mondelli, V., Dazzan, P., Gabilondo, A., Tournikioti, K., Walshe, M., Marshall, N., Schulze, K. K., Murray, R. M., McDonald, C., & Pariante, C. M. (2008) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2008.05.010 · Cited by 72
Enhanced adrenal sensitivity to adrenocorticotrophic hormone (ACTH) is evidence of HPA axis hyperactivity in Alzheimer's disease
O'Brien, J. T., Ames, D. J., Schweitzer, I., Mastwyk, M., & Colman, P. G. (1996) · Psychological Medicine · doi:10.1017/s0033291700033675 · Cited by 70
Hypothesis: Cytokines may be activated to cause depressive illness and chronic fatigue syndrome
Ur, E., White, P. D., & Grossman, A. B. (1992) · European Archives of Psychiatry and Clinical Neuroscience · doi:10.1007/bf02195983 · Cited by 68
The three-way interactions between the hypothalamic-pituitary-adrenal and gonadal axes and the immune system
Torpy, D. J., & Chrousos, G. P. (1996) · Baillière s Clinical Rheumatology · doi:10.1016/s0950-3579(96)80014-8 · Cited by 68
Pituitary gland volume in adolescent and young adult bipolar and unipolar depression
MacMaster, F. P., Leslie, R. A., Rosenberg, D. R., & Kusumakar, V. (2008) · Bipolar Disorders · doi:10.1111/j.1399-5618.2008.00476.x · Cited by 65
Volume of the adrenal and pituitary glands in depression
Kessing, L. V., Willer, I. S., & Knorr, U. B. (2010) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2010.05.007 · Cited by 63
Development and sexual dimorphism of the pituitary gland
MacMaster, F. P., Keshavan, M., Mirza, Y., Carrey, N., Upadhyaya, A. R., El-Sheikh, R., Buhagiar, C. J., Taormina, S. P., Boyd, C., Lynch, M., et al. (2007) · Life Sciences · doi:10.1016/j.lfs.2006.11.040 · Cited by 63
Meta-analyses Indicate Associations between Neuroendocrine Activation, Deactivation in Neurotrophic and Neuroimaging Markers in Depression after Stroke
Noonan, K., Carey, L. M., & Crewther, S. G. (2012) · Journal of Stroke and Cerebrovascular Diseases · doi:10.1016/j.jstrokecerebrovasdis.2012.09.008 · Cited by 63
Workshop report: the effects of psychological variables on the progression of HIV-1 disease
Kopnisky, K. L., Stoff, D. M., & Rausch, D. M. (2003) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2003.08.003 · Cited by 64
Pituitary Volume in Treatment-Naïve Pediatric Major Depressive Disorder
MacMaster, F. P., Russell, A., Mirza, Y., Keshavan, M. S., Taormina, S. P., Bhandari, R., Boyd, C., Lynch, M., Rose, M., Ivey, J., et al. (2006) · Biological Psychiatry · doi:10.1016/j.biopsych.2006.04.013 · Cited by 61
Childhood maltreatment, pituitary volume and adolescent hypothalamic-pituitary-adrenal axis – Evidence for a maltreatment-related attenuation
Kaess, M., Whittle, S., O’Brien-Simpson, L., Allen, N. B., & Simmons, J. G. (2018) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2018.08.004 · Cited by 64
A role for life events in the pathogenesis of Cushing's disease
Sonino, N., Fava, G. A., & Boscaro, M. (1993) · Clinical Endocrinology · doi:10.1111/j.1365-2265.1993.tb01004.x · Cited by 58
Estimating volumes of the pituitary gland from T1-weighted magnetic-resonance images: Effects of age, puberty, testosterone, and estradiol
Wong, A. P., Pipitone, J., Park, M. T. M., Dickie, E. W., Leonard, G. T., Perron, M., Pike, G. B., Richer, L., Veillette, S., Chakravarty, M. M., et al. (2014) · NeuroImage · doi:10.1016/j.neuroimage.2014.02.030 · Cited by 58
Novel Insights into Depression and Antidepressants: A Synergy Between Synaptogenesis and Neurogenesis?
Bambico, F. R., & Belzung, C. (2012) · Current topics in behavioral neurosciences · doi:10.1007/7854_2012_234 · Cited by 61
Cognition in mania and depression: Psychological models and clinical implications
Chamberlain, S. R., & Sahakian, B. J. (2004) · Current Psychiatry Reports · doi:10.1007/s11920-004-0010-3 · Cited by 60
Pituitary Volume in Pediatric Obsessive-Compulsive Disorder
MacMaster, F. P., Russell, A., Mirza, Y., Keshavan, M. S., Banerjee, S. P., Bhandari, R. P., Boyd, C. C., Lynch, M. A., Rose, M., Ivey, J., et al. (2005) · Biological Psychiatry · doi:10.1016/j.biopsych.2005.06.028 · Cited by 55
Hyperprolactinemia: Evaluation and Management
Blackwell, R. E. (1992) · Endocrinology and Metabolism Clinics of North America · doi:10.1016/s0889-8529(18)30234-2 · Cited by 55
Pathophysiology of hypercortisolism in depression: pituitary and adrenal responses to low glucocorticoid feedback
Carroll, B. J., Iranmanesh, A., Keenan, D. M., Cassidy, F., Wilson, W. H., & Veldhuis, J. D. (2011) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.2011.01821.x · Cited by 61
Imaging serotonergic neurotransmission in depression: hippocampal pathophysiology may mirror global brain alterations
Fujita, M., Charney, D. S., & Innis, R. B. (2000) · Biological Psychiatry · doi:10.1016/s0006-3223(00)00960-4 · Cited by 53
Changes in the immune system in depression and dementia: causal or coincidental effects?
Leonard, B. E., & Myint, A.-M. (2006) · Dialogues in Clinical Neuroscience · doi:10.31887/dcns.2006.8.2/bleonard · Cited by 52
Pituitary volume in neuroleptic-naïve schizophrenia: A structural MRI study
UPADHYAYA, A., ELSHEIKH, R., MACMASTER, F., DIWADKAR, V, & KESHAVAN, M. (2007) · Schizophrenia Research · doi:10.1016/j.schres.2006.09.033 · Cited by 51
Comparison of three methods for the estimation of the pituitary gland volume using magnetic resonance imaging: a stereological study
Ertekın, T., Acer, N., Turgut, A. T., Aycan, K., Özçelik, Ö., & Turgut, M. (2010) · Pituitary · doi:10.1007/s11102-010-0254-3 · Cited by 50
Pituitary volume mediates the relationship between pubertal timing and depressive symptoms during adolescence
Whittle, S., Yücel, M., Lorenzetti, V., Byrne, M. L., Simmons, J. G., Wood, S. J., Pantelis, C., & Allen, N. B. (2011) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2011.10.004 · Cited by 52
Structural studies of the hypothalamus and its nuclei in mood disorders
Schindler, S., Geyer, S., Strauß, M., Anwander, A., Hegerl, U., Turner, R., & Schönknecht, P. (2012) · Psychiatry Research Neuroimaging · doi:10.1016/j.pscychresns.2011.06.005 · Cited by 51
A unifying framework for depression: Bridging the major biological and psychosocial theories through stress
Roy, A., & Campbell, M. K. (2013) · Clinical and investigative medicine · doi:10.25011/cim.v36i4.19951 · Cited by 51
Cytokines and depression
Clow, A. (2002) · International review of neurobiology · doi:10.1016/s0074-7742(02)52012-2 · Cited by 48
Pituitary volume in patients with bipolar disorder and their first-degree relatives
Takahashi, T., Walterfang, M., Wood, S. J., Kempton, M. J., Jogia, J., Lorenzetti, V., Soulsby, B., Suzuki, M., Velakoulis, D., Pantelis, C., et al. (2009) · Journal of Affective Disorders · doi:10.1016/j.jad.2009.12.002 · Cited by 45
Abnormalities of the HPA axis in affective disorders: clinical subtypes and potential treatments
Porter, R., & Gallagher, P. (2006) · Acta Neuropsychiatrica · doi:10.1111/j.1601-5215.2006.00152.x · Cited by 47
Categorical prevalence and severity of hyperprolactinaemia in two UK cohorts of patients with severe mental illness during treatment with antipsychotics
Bushe, C., Yeomans, D., Floyd, T., & Smith, S. M. (2008) · Journal of Psychopharmacology · doi:10.1177/0269881107088436 · Cited by 45
Postmortem and Cerebrospinal Fluid Studies of Corticotropin‐releasing Factor in Humansa
HARTLINE, K. M., Owens, M. J., & Nemeroff, C. B. (1996) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1996.tb15114.x · Cited by 44
Self-citation
Antistress properties of antidepressant drugs and their clinical implications
Calabrese, F., Molteni, R., & Riva, M. A. (2011) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2011.05.007 · Cited by 42
Affective Disorders and Endocrine Disease
Fava, G. A. (1994) · Psychosomatics · doi:10.1016/s0033-3182(94)71755-2 · Cited by 42
Normal pituitary volumes in children and adolescents with bipolar disorder: A magnetic resonance imaging study
Chen, H. H., Nicoletti, M., Sanches, M., Hatch, J. P., Sassi, R. B., Axelson, D., Brambilla, P., Keshavan, M. S., Ryan, N. D., Birmaher, B. B., et al. (2004) · Depression and Anxiety · doi:10.1002/da.20044 · Cited by 39
Longitudinal volume changes of the pituitary gland in patients with schizotypal disorder and first-episode schizophrenia
Takahashi, T., Zhou, S.-Y., Nakamura, K., Tanino, R., Furuichi, A., Kido, M., Kawasaki, Y., Noguchi, K., Seto, H., Kurachi, M., et al. (2010) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2010.10.023 · Cited by 38
Increased pituitary volume in schizophrenia spectrum disorders
Takahashi, T., Suzuki, M., Velakoulis, D., Lorenzetti, V., Soulsby, B., Zhou, S.-Y., Nakamura, K., Seto, H., Kurachi, M., & Pantelis, C. (2009) · Schizophrenia Research · doi:10.1016/j.schres.2008.12.016 · Cited by 37
Corticotropin-releasing factor-binding protein, stress and major depression
Eede, F. V. D., Broeckhoven, C. V., & Claes, S. J. (2005) · Ageing Research Reviews · doi:10.1016/j.arr.2005.02.002 · Cited by 37
Smaller pituitary volume in adult patients with obsessive–compulsive disorder
Atmaca, M., Yıldırım, H., Özler, S., Koç, M., Kara, B., & Seç, S. (2009) · Psychiatry and Clinical Neurosciences · doi:10.1111/j.1440-1819.2009.01981.x · Cited by 37
Pituitary gland volume in currently depressed and remitted depressed patients
Lorenzetti, V., Allen, N. B., Fornito, A., Pantelis, C., De Plato, G., Ang, A., & Yücel, M. (2009) · Psychiatry Research: Neuroimaging · doi:10.1016/j.pscychresns.2008.06.006 · Cited by 37

Authors: KRISHNAN, K. R. R., DORAISWAMY, P. M., LURIE, S. N., FIGIEL, G. S., HUSAIN, M. M., BOYKO, O. B., ELLINWOOD, E. H., & NEMEROFF, C. B.
Affiliations: Duke University (US)
ORCID: KRISHNAN, K. RANGA RAMA
DORAISWAMY, P. MURALI
HUSAIN, MUSTAFA M.
BOYKO, OREST B.
NEMEROFF, CHARLES B.
Venue: The Journal of Clinical Endocrinology & Metabolism
Publisher: The Endocrine Society
Published: 1991-02
Volume: 72
Issue: 2
Pages: 256-259
ISSN: 0021-972X (ISSN-L)
1945-7197
DOI: 10.1210/jcem-72-2-256
OpenAlex: W2051225255
Cited by: 232
References: 9
Citations by year: 2026: 1 · 2024: 1 · 2023: 3 · 2022: 2 · 2020: 2 · 2019: 1 · 2018: 1 · 2017: 3 · 2016: 5 · 2015: 7 · 2014: 7 · 2013: 4 · 2012: 6
FWCI: 4.74
Type: journal article
Language: en
Open access: closed
Locations: The Journal of Clinical Endocrinology & Metabolism (publishedVersion)
PubMed (publishedVersion)
Funders: National Institutes of Health (5r01mh044716-06)
National Institute of Mental Health (R01MH042088, MH-44716, MH 40159, MH42088)
Topics: Life Sciences › Neuroscience › Behavioral Neuroscience › Stress Responses and Cortisol
Health Sciences › Medicine › Pharmacology (medical) › Treatment of Major Depression
Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Pituitary Gland Disorders and Treatments
Keywords: major depressive disorder, pituitary volume, pituitary stalk, brain structural changes, geriatric depression, neuroimaging of depression
MeSH terms: Adult, Aged, Aged, 80 and over, Aging, Depressive Disorder, Female, Humans, Magnetic Resonance Imaging, Middle Aged, Pituitary Gland

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Pituitary Size in Depression*

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks