The DOI matches its Crossref record; 14 of the 14 references it cites were found in a registry or an index.
Consensus definitions proposed for pediatric multiple sclerosis and related disorders
Abstract
BACKGROUND: The CNS inflammatory demyelinating disorders of childhood include both self-limited and lifelong conditions, which can be indistinguishable at the time of initial presentation. Clinical, biologic, and radiographic delineation of the various monophasic and chronic childhood demyelinating disorders requires an operational classification system to facilitate prospective research studies. METHODS: The National Multiple Sclerosis Society (NMSS) organized an International Pediatric MS Study Group (Study Group) composed of adult and pediatric neurologists and experts in genetics, epidemiology, neuropsychology, nursing, and immunology. The group met several times to develop consensus definitions regarding the major CNS inflammatory demyelinating disorders of children and adolescents. RESULTS: Clinical definitions are proposed for pediatric multiple sclerosis (MS), acute disseminated encephalomyelitis (ADEM), recurrent ADEM, multiphasic ADEM, neuromyelitis optica, and clinically isolated syndrome. These definitions are considered operational and need to be tested in future research and modified accordingly. CONCLUSION: CNS inflammatory demyelinating disorders presenting in children and adolescents can be defined and distinguished. However, prospective research is necessary to determine the validity and utility of the proposed diagnostic categories.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
New diagnostic criteria for multiple sclerosis: Guidelines for research protocols
Poser, C. M., Paty, D. W., Scheinberg, L., McDonald, W. I., Davis, F. A., Ebers, G. C., Johnson, K. P., Sibley, W. A., Silberberg, D. H., & Tourtellotte, W. W. (1983) · Annals of Neurology · doi:10.1002/ana.410130302 · Cited by 7,384
McDonald, W. I., Compston, A., Edan, G., Goodkin, D., Hartung, H., Lublin, F. D., McFarland, H. F., Paty, D. W., Polman, C. H., Reingold, S. C., et al. (2001) · Annals of Neurology · doi:10.1002/ana.1032 · Cited by 6,969
Schumacher, G. A., Beebe, G., Kibler, R. F., Kurland, L. T., Kurtzke, J. F., McDowell, F., Nagler, B., Sibley, W. A., Tourtellotte, W. W., & Willmon, T. L. (1965) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1965.tb20235.x · Cited by 1,438
Acute disseminated encephalomyelitis: A long-term follow-up study of 84 pediatric patients
Tenembaum, S., Chamoles, N., & Fejerman, N. (2002) · Neurology · doi:10.1212/wnl.59.8.1224 · Cited by 710
Self-citationDale, R. C. (2000) · Brain · doi:10.1093/brain/123.12.2407 · Cited by 703
Clinical and neuroradiologic features of acute disseminated encephalomyelitis in children
Hynson, J. L., Kornberg, A. J., Coleman, L. T., Shield, L., Harvey, A. S., & Kean, M. J. (2001) · Neurology · doi:10.1212/wnl.56.10.1308 · Cited by 539
Neuromyelitis optica: Clinical predictors of a relapsing course and survival
Wingerchuk, D. M., & Weinshenker, B. G. (2003) · Neurology · doi:10.1212/01.wnl.0000049912.02954.2c · Cited by 331
Mikaeloff, Y., Suissa, S., Vallée, L., Lubetzki, C., Ponsot, G., Confavreux, C., Tardieu, M., & KIDMUS Study Group (2004) · The Journal of Pediatrics · doi:10.1016/j.jpeds.2003.10.056 · Cited by 321
MRI prognostic factors for relapse after acute CNS inflammatory demyelination in childhood
Mikaeloff, Y. (2004) · Brain · doi:10.1093/brain/awh218 · Cited by 259
The ALSFRSr predicts survival time in an ALS clinic population
Kaufmann, P., Levy, G., Thompson, J. L. P., DelBene, M. L., Battista, V., Gordon, P. H., Rowland, L. P., Levin, B., & Mitsumoto, H. (2005) · Neurology · doi:10.1212/01.wnl.0000148648.38313.64 · Cited by 243
Cited by
Diagnostic criteria for multiple sclerosis: 2010 revisions to the McDonald criteria
Polman, C. H., Reingold, S. C., Banwell, B., Clanet, M., Cohen, J. A., Filippi, M., Fujihara, K., Havrdova, E., Hutchinson, M., Kappos, L., et al. (2011) · Annals of Neurology · doi:10.1002/ana.22366 · Cited by 9,802
Self-citationKrupp, L. B., Tardieu, M., Amato, M. P., Banwell, B., Chitnis, T., Dale, R. C., Ghezzi, A., Hintzen, R., Kornberg, A., Pohl, D., et al. (2013) · Multiple Sclerosis Journal · doi:10.1177/1352458513484547 · Cited by 1,130
Self-citationDifferential diagnosis of suspected multiple sclerosis: a consensus approach
Miller, D., Weinshenker, B., Filippi, M., Banwell, B., Cohen, J., Freedman, M., Galetta, S., Hutchinson, M., Johnson, R., Kappos, L., et al. (2008) · Multiple Sclerosis Journal · doi:10.1177/1352458508096878 · Cited by 642
Self-citationAcute disseminated encephalomyelitis
Tenembaum, S., Chitnis, T., Ness, J., & Hahn, J. S. (2007) · Neurology · doi:10.1212/01.wnl.0000259404.51352.7f · Cited by 631
Self-citationMiller, D. H., Chard, D. T., & Ciccarelli, O. (2012) · The Lancet Neurology · doi:10.1016/s1474-4422(11)70274-5 · Cited by 507
Metadata
- Authors
- Krupp, L. B., Banwell, B., & Tenembaum, S.
- Venue
- Neurology
- Published
- 2007-04-17
- Volume
- 68
- Issue
- 16_suppl_2
- Pages
- S7-12
- ISSN
- 0028-3878 (ISSN-L)
- 1526-632X
- OpenAlex
- W2161944076
- Cited by
- 755
- References
- 14
- FWCI
- 30.66
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Consensus definitions proposed for pediatric multiple sclerosis and related disorders. https://app.cochat.ai/papers/10.1212/01.wnl.0000259422.44235.a8
- The paper
- Krupp, L. B., Banwell, B., & Tenembaum, S. (2007). Consensus definitions proposed for pediatric multiple sclerosis and related disorders. Neurology. https://doi.org/10.1212/01.wnl.0000259422.44235.a8
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.