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The DOI matches its Crossref record; 14 of the 14 references it cites were found in a registry or an index.

Consensus definitions proposed for pediatric multiple sclerosis and related disorders

Krupp, Lauren B., Banwell, Brenda, Tenembaum, Silvia·2007·Neurology

Abstract

BACKGROUND: The CNS inflammatory demyelinating disorders of childhood include both self-limited and lifelong conditions, which can be indistinguishable at the time of initial presentation. Clinical, biologic, and radiographic delineation of the various monophasic and chronic childhood demyelinating disorders requires an operational classification system to facilitate prospective research studies. METHODS: The National Multiple Sclerosis Society (NMSS) organized an International Pediatric MS Study Group (Study Group) composed of adult and pediatric neurologists and experts in genetics, epidemiology, neuropsychology, nursing, and immunology. The group met several times to develop consensus definitions regarding the major CNS inflammatory demyelinating disorders of children and adolescents. RESULTS: Clinical definitions are proposed for pediatric multiple sclerosis (MS), acute disseminated encephalomyelitis (ADEM), recurrent ADEM, multiphasic ADEM, neuromyelitis optica, and clinically isolated syndrome. These definitions are considered operational and need to be tested in future research and modified accordingly. CONCLUSION: CNS inflammatory demyelinating disorders presenting in children and adolescents can be defined and distinguished. However, prospective research is necessary to determine the validity and utility of the proposed diagnostic categories.

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Metadata

Authors
Krupp, L. B., Banwell, B., & Tenembaum, S.
Venue
Neurology
Published
2007-04-17
Volume
68
Issue
16_suppl_2
Pages
S7-12
ISSN
  • 0028-3878 (ISSN-L)
  • 1526-632X
OpenAlex
W2161944076
Cited by
755
References
14
FWCI
30.66
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Consensus definitions proposed for pediatric multiple sclerosis and related disorders. https://app.cochat.ai/papers/10.1212/01.wnl.0000259422.44235.a8
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Krupp, L. B., Banwell, B., & Tenembaum, S. (2007). Consensus definitions proposed for pediatric multiple sclerosis and related disorders. Neurology. https://doi.org/10.1212/01.wnl.0000259422.44235.a8

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