Cited by 385Dementia and Cognitive Impairment ResearchTreatment of Major DepressionCancer-related cognitive impairment studies

The DOI matches its Crossref record; 38 of the 38 references it cites were found in a registry or an index.

Recurrent depressive symptoms and the incidence of dementia and mild cognitive impairment

Open access

Dotson, Vonetta M., Beydoun, May A., Zonderman, Alan B.·2010·Neurology

DOI 10.1212/wnl.0b013e3181e62124PMC PMC2906403

Open this paper in CoChat — free account

Abstract

OBJECTIVE: A history of depression has been linked to an increased dementia risk. This risk may be particularly high in recurrent depression due to repeated brain insult. We investigated whether there is a dose-dependent relationship between the number of episodes of elevated depressive symptoms (EDS) and the risk for mild cognitive impairment (MCI) and dementia. METHODS: A total of 1,239 older adults from the Baltimore Longitudinal Study of Aging were followed for a median of 24.7 years. Diagnoses of MCI and dementia were made based on prospective data. Participants completed the Center for Epidemiologic Studies Depression Scale at 1- to 2-year intervals and were considered to have an EDS if their score was > or = 16. Kaplan-Meier survival curves, log-rank test for trend for survivor functions, and Cox proportional hazards models were conducted to examine the risk of MCI and dementia by number of EDS. RESULTS: We observed a monotonic increase in risk for all-cause dementia and Alzheimer disease as a function of the number of EDS. Each episode was associated with a 14% increase in risk for all-cause dementia. Having 1 EDS conferred an 87%-92% increase in dementia risk, while having 2 or more episodes nearly doubled the risk. Recurrence of EDS did not increase the risk of incident MCI. CONCLUSIONS: Our findings support the hypothesis that depression is a risk factor for dementia and suggest that recurrent depression is particularly pernicious. Preventing the recurrence of depression in older adults may prevent or delay the onset of dementia.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1212/wnl.0b013e3181e62124

Cites

38 of 38 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Clinical diagnosis of Alzheimer's disease: Report of the NINCDS‐ADRDA Work Group* under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease
McKhann, G., Drachman, D., Folstein, M., Katzman, R., Price, D., & Stadlan, E. M. (1984) · Neurology · doi:10.1212/wnl.34.7.939 · Cited by 27,915
Mild cognitive impairment as a diagnostic entity
Petersen, R. C. (2004) · Journal of Internal Medicine · doi:10.1111/j.1365-2796.2004.01388.x · Cited by 7,864
The Association Between Quantitative Measures of Dementia and of Senile Change in the Cerebral Grey Matter of Elderly Subjects
Blessed, G., Tomlinson, B. E., & Roth, M. (1968) · British Journal of Psychiatry · doi:10.1192/bjp.114.512.797 · Cited by 4,117
Prevalence of Neuropsychiatric Symptoms in Dementia and Mild Cognitive Impairment: Results From the Cardiovascular Health Study
Lyketsos, C. G., Lopez, O., Jones, B., Fitzpatrick, A. L., Breitner, J., & DeKosky, S. (2002) · JAMA · doi:10.1001/jama.288.12.1475 · Cited by 2,049
Clinical Dementia Rating: A Reliable and Valid Diagnostic and Staging Measure for Dementia of the Alzheimer Type
Morris, J. C. (1997) · International Psychogeriatrics · doi:10.1017/s1041610297004870 · Cited by 1,641
Risk Factors for Depression Among Elderly Community Subjects: A Systematic Review and Meta-Analysis
Cole, M. G., & Dendukuri, N. (2003) · American Journal of Psychiatry · doi:10.1176/appi.ajp.160.6.1147 · Cited by 1,368
Why stress is bad for your brain
Sapolsky, R. M. (1996) · Science · doi:10.1126/science.273.5276.749 · Cited by 1,306
Prodromal Alzheimer's disease: successive emergence of the clinical symptoms
Amieva, H., Le Goff, M., Millet, X., Orgogozo, J. M., Pérès, K., Barberger‐Gateau, P., Jacqmin‐Gadda, H., & Dartigues, J. F. (2008) · Annals of Neurology · doi:10.1002/ana.21509 · Cited by 737
Tables of the number of patients required in clinical trials using the logrank test
Freedman, L. S. (1982) · Statistics in Medicine · doi:10.1002/sim.4780010204 · Cited by 722
Poststroke dementia
Leys, D., Hénon, H., Mackowiak-Cordoliani, M.-A., & Pasquier, F. (2005) · The Lancet Neurology · doi:10.1016/s1474-4422(05)70221-0 · Cited by 609

Show all 38 references

Research works printed but not linked: 2

Radloff LS. The CES-D Scale: a self-report depression scale for research in the general population. Appl Psychol Meas 1977;1:385–401.
10.1097/00019442-200411000-00012 · DOI

Sorted by citations

Items 201–300 of 385

Changes in neighborhood-level socioeconomic disadvantage and older Americans’ cognitive functioning
Settels, J., & Leist, A. K. (2021) · Health & Place · doi:10.1016/j.healthplace.2021.102510 · Cited by 14
Neurodegeneration, β‐amyloid and mood disorders: state of the art and future perspectives
Piccinni, A., Origlia, N., Veltri, A., Vizzaccaro, C., Marazziti, D., Vanelli, F., Moroni, I., Domenici, L., & Dell’Osso, L. (2012) · International Journal of Geriatric Psychiatry · doi:10.1002/gps.3879 · Cited by 14
Changes in dementia risk along with onset age of depression: a longitudinal cohort study of elderly depressed patients
Jang, Y. J., Kim, M.-J., Moon, Y. K., Lim, S., & Kim, D. K. (2025) · BMC Psychiatry · doi:10.1186/s12888-025-06683-w · Cited by 13
Neuropsychology of Alzheimer’s disease: From preclinical phase to dementia
Buyukiscan, E. S. (2025) · Applied Neuropsychology Adult · doi:10.1080/23279095.2025.2469236 · Cited by 15
Midlife risk factors for late-life cognitive decline
Carroll, S. L., & Turkheimer, E. N. (2018) · Developmental Review · doi:10.1016/j.dr.2018.01.001 · Cited by 15
Recurrent stress across life may improve cognitive performance in individual rats, suggesting the induction of resilience
Hadar, R., Edemann-Callesen, H., Hlusicka, E. B., Wieske, F., Vogel, M., Günther, L., Vollmayr, B., Hellweg, R., Heinz, A., Garthe, A., et al. (2019) · Translational Psychiatry · doi:10.1038/s41398-019-0523-5 · Cited by 14
Dementia: Psychosocial/Mental Health Risk Factors
Nasisi, C. R. (2020) · The Journal for Nurse Practitioners · doi:10.1016/j.nurpra.2020.03.013 · Cited by 17
Mild Cognitive Impairment in the Elderly
Энгманн, Б. (2011) · GeroPsych · doi:10.1024/1662-9647/a000036 · Cited by 15
Cognitive impairment without dementia: A current view of the problem
Starchina, Y. A. (2017) · Neurology neuropsychiatry Psychosomatics · doi:10.14412/2074-2711-2017-2-71-76 · Cited by 13
Association between dementia and psychiatric disorders in long-term care residents
Tori, K., Kalligeros, M., Nanda, A., Shehadeh, F., van Aalst, R., Chit, A., & Mylonakis, E. E. (2020) · Medicine · doi:10.1097/md.0000000000021412 · Cited by 15
Detection and Prediction of Incident Alzheimer Dementia over a 10-Year or Longer Medical History: A Population-Based Study in Primary Care
Grande, G., Vetrano, D. L., Mazzoleni, F., Lovato, V., Pata, M., Cricelli, C. A., & Lapi, F. (2020) · Dementia and Geriatric Cognitive Disorders · doi:10.1159/000509379 · Cited by 13
An analysis of dynamic, bidirectional associations between memory and verbal fluency with depressive symptoms in middle- and older-aged adults: A cohort study
Best, J. R., & Cosco, T. D. (2022) · Journal of Affective Disorders · doi:10.1016/j.jad.2022.09.019 · Cited by 12
Modifiable Risk Factors Associated With Cognitive Decline in Late Life Depression: Findings From the Canadian Longitudinal Study on Aging: Facteurs de risque modifiables associés au déclin cognitif dans la dépression en fin de vie : constatations de l'Étude longitudinale canadienne sur le vieillissement
Wong, M. F., Kiss, A., Herrmann, N., Lanctôt, K. L., & Gallagher, D. (2024) · The Canadian Journal of Psychiatry · doi:10.1177/07067437241255095 · Cited by 14
The association between ‘weekend warrior’, regular exercise, and cognitive function in elderly individuals with and without depressive symptoms: A cross-sectional analysis from NHANES 2011–2014
Wu, J., Qiu, P., & Li, Y. (2024) · Journal of Affective Disorders · doi:10.1016/j.jad.2024.08.184 · Cited by 12
A long-term longitudinal follow-up of depressed patients treated with ECT with special focus on development of dementia
Berggren, Å., Gustafson, L., Höglund, P., & Johanson, A. M. (2016) · Journal of Affective Disorders · doi:10.1016/j.jad.2016.04.004 · Cited by 12
Depression is a major risk factor for the development of dementia in people with lower urinary tract symptoms: A nationwide population-based study
Ou, M.-J., Huang, C., Wang, Y.-C., Chen, Y., Ho, C., Wu, M., Huang, Y., Wu, C., & Chen, P. (2019) · PLoS ONE · doi:10.1371/journal.pone.0217984 · Cited by 13
Apolipoprotein E4 increases the risk of depression recurrence
Obinata, M., Maeshima, H., Yoshinari, N., Natume, S., Saida, T., Yasuda, S., Ichikawa, T., Suzuki, T., & Baba, H. (2021) · Journal of Affective Disorders · doi:10.1016/j.jad.2021.08.089 · Cited by 12
Risk assessment and stratification of mild cognitive impairment among the Chinese elderly: attention to modifiable risk factors
Wang, Q., Zhou, S., Zhang, J., Wáng, Q., Hou, F., Han, X., Shen, G., & Zhang, Y. (2023) · Journal of Epidemiology & Community Health · doi:10.1136/jech-2022-219952 · Cited by 13
Adverse life event and risk of cognitive impairment: a 5‐year prospective longitudinal study in Chongqing, China
Deng, J., Lian, Y., Shen, C., Chen, Y., Zhang, M., Wang, Y.-J., & Zhou, H.-D. (2012) · European Journal of Neurology · doi:10.1111/j.1468-1331.2011.03599.x · Cited by 13
Depression and dementia
Beal, E. (2010) · Nature Reviews Neurology · doi:10.1038/nrneurol.2010.123 · Cited by 12
Depression in dementia patients: issues and challenges for a physician.
Deep, R., & Sagar, R. (2011) · PubMed · Cited by 12
Severity and treatment of cognitive impairment
Starchina, Y. A., & Zakharov, V. V. (2021) · Neurology neuropsychiatry Psychosomatics · doi:10.14412/2074-2711-2021-3-119-124 · Cited by 15
Depression in Mid- and Later-Life and Risk of Dementia in Women: A Prospective Study within the Danish Nurses Cohort
Hickey, M., Hueg, T. K., Priskorn, L., Uldbjerg, C. S., Beck, A. L., Anstey, K. J., Lim, Y., & Bräuner, E. V. (2023) · Journal of Alzheimer s Disease · doi:10.3233/jad-230091 · Cited by 11
Constricting Life Space and Likelihood of Neurodegenerative Disease in Community-Dwelling Older Men
Bock, M., Hoang, T. D. M., Cawthon, P. M., Mackey, D. C., Patel, S., Hillier, T. A., & Yaffe, K. S. (2023) · JAMA Network Open · doi:10.1001/jamanetworkopen.2023.42670 · Cited by 11
The prevalence of mild cognitive impairment in Gulf War veterans: a follow-up study
Chao, L. L., Sullivan, K. A., Krengel, M., Killiany, R., Steele, L., Klimas, N. G., & Koo, B. (2024) · Frontiers in Neuroscience · doi:10.3389/fnins.2023.1301066 · Cited by 11
Vascular Burden and Cognitive Function in Late-Life Depression
Zuidersma, M., Izaks, G. J., Naarding, P., Comijs, H. C., & Voshaar, R. C. O. (2014) · American Journal of Geriatric Psychiatry · doi:10.1016/j.jagp.2014.06.010 · Cited by 11
Prevalence of neuropsychiatric conditions and cognitive impairment in two parallel, aging study cohorts from rural and urban India
Sundarakumar, J. S., Abhishek, M. L., Jain, S., Hameed, S. K. S., Teams, S. &. T. S., & Ravindranath, V. (2022) · Alzheimer s & Dementia · doi:10.1002/alz.12741 · Cited by 13
The impact of Alzheimer’s disease risk factors on the pupillary light response
Sparks, S., Pinto, J., Hayes, G., Spitschan, M., & Bulte, D. P. (2023) · Frontiers in Neuroscience · doi:10.3389/fnins.2023.1248640 · Cited by 10
Plasma levels of Interleukin 18 but not amyloid-β or Tau are elevated in female depressive patients
Liu, F., Yang, L., Zheng, H. S., Zhou, Y., Chen, B.-B., Xu, H., Zhang, Y., & Shen, D. (2020) · Comprehensive Psychiatry · doi:10.1016/j.comppsych.2020.152159 · Cited by 12
Cognitive Impairment in Old Age
Nuovo, S. D., Béni, R. D., Borella, E., Marková, H., Laczó, J., & Vyhnálek, M. (2020) · European Psychologist · doi:10.1027/1016-9040/a000391 · Cited by 11
Different Sides of Depression in the Elderly: An In-depth View on the Role of Aβ Peptides
Pagni, G., Tagliarini, C., Carbone, M. G., Imbimbo, B. P., Marazziti, D., & Pomara, N. (2021) · Current Medicinal Chemistry · doi:10.2174/0929867328666210921164816 · Cited by 10
Geriatric impairments were directly and indirectly associated with mortality in older patients with cancer: a structural equation analysis
Canouï‐Poitrine, F., Martinez‐Tapia, C., Paillaud, É., Mathoulin‐Pélissier, S., Pamoukdjian, F., Frasca, M., Tolppanen, A., Bringuier, M., Brain, E. G. C., Broussier, A., et al. (2022) · Journal of Clinical Epidemiology · doi:10.1016/j.jclinepi.2022.04.004 · Cited by 10
Depressive symptoms as predictor of dementia versus continuous cognitive decline: a 3-year prospective study
Neubauer, A. B., Wahl, H., & Bickel, H. (2012) · European Journal of Ageing · doi:10.1007/s10433-012-0246-4 · Cited by 11
The Short- and Long-Term Effects of Psychobehavioral Correlates in Buffering Diabetes-Related Cognitive Decline
Chiu, C., Hu, S. C., Wray, L. A., & Wu, S.-T. (2016) · Annals of Behavioral Medicine · doi:10.1007/s12160-016-9770-3 · Cited by 10
Differentiating Alzheimer’s disease from mild cognitive impairment: a quick screening tool based on machine learning
Lü, W., Zhang, M., Yu, W., Kuang, W., Chen, L., Zhang, W., Yu, J., & Lü, Y. (2023) · BMJ Open · doi:10.1136/bmjopen-2023-073011 · Cited by 9
Diligent for better or worse: Conscientiousness is associated with higher likelihood of suicidal behavior and more severe suicidal intent in later life
Szücs, A., Galfalvy, H., Alessi, M. G., Kenneally, L. B., Valderas, J. M., Maier, A. B., & Szántó, K. (2024) · Comprehensive Psychiatry · doi:10.1016/j.comppsych.2024.152523 · Cited by 12
The prevalence and clinical correlation factors of cognitive impairment in patients with major depressive disorder hospitalized during the acute phase
Zhao, H., & Chen, J. (2024) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2024.1497658 · Cited by 9
Depression in Older Adults
Casey, D. (2018) · Physician Assistant Clinics · doi:10.1016/j.cpha.2018.05.009 · Cited by 9
Determinants of poor cognitive function using A-IQCODE among Lebanese older adults: a cross-sectional study
Bou-Orm, I. R., Khamis, A. M., & Chaaya, M. (2017) · Aging & Mental Health · doi:10.1080/13607863.2017.1301879 · Cited by 9
Development and internal validation of a prognostic model for 15-year risk of Alzheimer dementia in primary care patients
Grande, G., Vetrano, D. L., Marconi, E., Bianchini, E., Cricelli, I., Lovato, V., Guglielmini, L., Taddeo, D., Cappa, S. F., Cricelli, C. A., et al. (2022) · Neurological Sciences · doi:10.1007/s10072-022-06258-7 · Cited by 9
Influence of Depressive Symptoms on Dopaminergic Treatment of Parkinson’s Disease
Hanganu, A., Degroot, C., Monchi, O., Bedetti, C., Mejia‐Constain, B., Lafontaine, A., Chouinard, S., & Bruneau, M. (2014) · Frontiers in Neurology · doi:10.3389/fneur.2014.00188 · Cited by 11
Serious games for ageing: a pilot interventional study in a cohort of heterogeneous cognitive impairment
Simões, M. A., Abreu, R., Gonçalves, H., Rodrigues, A. P., Bernardino, I., & Castelo-Branco, M. S. (2019) · SeGAH ... IEEE ... International Conference on Serious Games and Applications for Health/IEEE International Conference on Serious Games and Applications for Health · doi:10.1109/segah.2019.8882431 · Cited by 8
Association between caring for grandchildren based on living arrangements and cognitive function among Chinese middle-aged and older adults: The mediating roles of social activities and depressive symptoms
Hou, X., Yuan, X., Qiao, G., & Zhou, J. W. (2023) · Frontiers in Public Health · doi:10.3389/fpubh.2023.1105066 · Cited by 11
Trastornos del Ánimo y Demencia. Aspectos clínicos y estudios complementarios en el diagnóstico diferencial
Iribarne, C., Renner, V., Pérez, C., & David Ladrón de Guevara, H. (2020) · Revista Médica Clínica Las Condes · doi:10.1016/j.rmclc.2020.02.001 · Cited by 15
Prevalence of Depressive Symptoms in a Memory Clinic Cohort: A Retrospective Study
Loreto, F., Fitzgerald, A., Golemme, M., Gunning, S., Win, Z., Patel, N., Carswell, C. J., Perry, R. J., Kennedy, A. M., Edison, P., et al. (2022) · Journal of Alzheimer s Disease · doi:10.3233/jad-220170 · Cited by 8
Dementia
Kaufman, D. M., Geyer, H. L., & Milstein, M. J. (2017) · Elsevier eBooks · doi:10.1016/b978-0-323-41559-0.00007-1 · Cited by 8
Long-term outcome following electroconvulsive therapy for late-life depression: five-year follow-up data from the MODECT study
Lambrichts, S., Wagenmakers, M. J., Vansteelandt, K., Obbels, J., Schouws, S. N. T. M., Verwijk, E., van Exel, E., Bouckaert, F., Vandenbulcke, M., Schrijvers, D., et al. (2022) · The American Journal of Geriatric Psychiatry · doi:10.1016/j.jagp.2022.05.010 · Cited by 7
Non-cognitive psychopathological symptoms in mild cognitive impairment
Cherkasov, N. S., & Колыхалов, И. В. (2021) · S S Korsakov Journal of Neurology and Psychiatry · doi:10.17116/jnevro202112110241 · Cited by 7
The Role of Depression and Anxiety in the Relationship Between Arthritis and Cognitive Impairment in Chinese Older Adults
He, Y., Ding, K., Tan, W., Ke, Y.-F., Hou, C., Jia, F., & Wang, S.-B. (2024) · American Journal of Geriatric Psychiatry · doi:10.1016/j.jagp.2024.01.228 · Cited by 7
Association between concurrent antidepressant and hypnotic treatment and the risk of dementia: A nationwide cohort study
Lin, C., Lee, M., Kao, S., Chung, C., Chen, L., Chou, P., Lee, J.-F., & Chien, W. (2020) · Journal of Affective Disorders · doi:10.1016/j.jad.2020.08.025 · Cited by 8
Longitudinal Predictors of Informant-Rated Everyday Function in Mild Cognitive Impairment
Divers, R. M., Vito, A. N. D., Pugh, E., Robinson, A. D., Weitzner, D. S., & Calamia, M. R. (2022) · Journal of Geriatric Psychiatry and Neurology · doi:10.1177/08919887221093360 · Cited by 8
Common Neuropsychiatric Symptoms in Alzheimer’s Disease, Mild Cognitive Impairment, and Subjective Memory Complaints: A Unified Framework
Warren, S. L., Hamza, E. A., Tindle, R., Reid, E., Whitfield, P., Doumit, A., & Moustafa, A. A. (2023) · Current Alzheimer Research · doi:10.2174/0115672050255489231012072014 · Cited by 7
Patterns of late‐life depressive symptoms and subsequent declines in cognitive domains
Gillis, J. C., Chang, S., Devore, E. E., ROSNER, B. A., Grodstein, F., & Okereke, O. I. (2016) · International Journal of Geriatric Psychiatry · doi:10.1002/gps.4618 · Cited by 7
Relationship between depressive symptomatology and cognitive performance in older people
Izquierdo-Guerra, K. I., Montoya-Arenas, D., Franco, J., & Gaviria, A. (2018) · International Journal of Psychological Research · doi:10.21500/20112084.3520 · Cited by 6
Dementia
Kaufman, D. M., Geyer, H. L., Milstein, M. J., & Rosengard, J. L. (2022) · Elsevier eBooks · doi:10.1016/b978-0-323-79680-4.00007-3 · Cited by 6
The relationship between depressive symptoms and subtypes of mild cognitive impairment in post‐menopausal women: Results from the Women's Health Initiative Memory Study
Korthauer, L. E., Goveas, J. S., Rapp, S. R., Espeland, M. A., Shumaker, S. A., Garcia, K. R., Rossom, R. C., García, L., Tindle, H. A., Salmoirago‐Blotcher, E., et al. (2022) · International Journal of Geriatric Psychiatry · doi:10.1002/gps.5817 · Cited by 6
Long-Term Depressive Symptom Trajectories and Midlife Cognition
Grasset, L., Hazzouri, A. Z. A., Milazzo, F., Lu, P., Elfassy, T., Elbejjani, M., Vittinghoff, E., & Yaffe, K. S. (2024) · Neurology · doi:10.1212/wnl.0000000000209510 · Cited by 6
BPEN: Brain Posterior Evidential Network for trustworthy brain imaging analysis
Ye, K., Tang, H., Dai, S., Fortel, I., Thompson, P. M., Mackin, R. S., Leow, A., Huang, H., & Zhan, L. (2024) · Neural Networks · doi:10.1016/j.neunet.2024.106943 · Cited by 6
Exploring the Complex Relationship Between Antidepressants, Depression and Neurocognitive Disorders
Neațu, M., Ioniță, I., Jugurt, A., Davidescu, E. I., & Popescu, B. O. (2024) · Biomedicines · doi:10.3390/biomedicines12122747 · Cited by 7
Sex‐specific association of depressive symptom trajectories with cognitive decline and clinical progression in mild cognitive impairment
Wang, X., Ye, T., Initiative, A. D. N., Zhou, W., & Zhang, J. (2025) · Alzheimer s & Dementia · doi:10.1002/alz.70548 · Cited by 6
Cognitive performance among older adults with psychotic depression compared to non-psychotic depression
Vermeulen, T., Sabbe, B., Østergaard, S. D., Giltay, E. J., & van der Mast, R. C. (2022) · Psychiatry Research · doi:10.1016/j.psychres.2022.114996 · Cited by 6
Approaches to engage an aging, rural cohort in southern India during the COVID‐19 crisis and the psychological impact of COVID‐19 in this cohort
Sundarakumar, J. S., Hameed, S. K. S., Dilip, B., Deepak, S., Kumar, B. R., & Ravindranath, V. (2022) · Alzheimer s & Dementia · doi:10.1002/alz.12726 · Cited by 7
A Study on Occupational Reminiscence Therapy(ORT) Program for the Elderly with Mild Cognitive Impairment(MCI) in Local Community
Cha, Y.-J. (2016) · Journal of the Korea Academia-Industrial cooperation Society · doi:10.5762/kais.2016.17.8.605 · Cited by 6
The N-3 polyunsaturated fatty acids supplementation to prevent depression recurrence in patients with late-life depression: a 52-week double-blind, placebo-controlled trial
Cheng, Y.-C., Chen, W.-Y., Lin, C., Lee, S.-H., Chiu, C.-C., & Kuo, P.-H. (2025) · Journal of Affective Disorders · doi:10.1016/j.jad.2024.09.129 · Cited by 5
Cortical thickness and low-grade inflammation moderate the association between depressive symptoms and cognitive function in early widowhood: A preliminary study
Wu‐Chung, E. L., Kennedy, K. M., Medina, L. D., Schulz, P. E., Oswald, F. L., Heijnen, C. J., Leal, S. L., Denny, B. T., & Fagundes, C. P. (2025) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2025.06.027 · Cited by 6
Anxious–depressive symptoms and sleep disturbances across the Alzheimer disease spectrum
Chai, Y., Kojori, E. S., Saykin, A. J., & Yu, M. (2025) · Nature Mental Health · doi:10.1038/s44220-025-00416-4 · Cited by 8
Prevalence and Associated Factors of Cognitive Impairment and Poor Sleep Quality among Community-Dwelling Older Adults in Northern Thailand
Nanthakwang, N., Siviroj, P., Matanasarawoot, A., Sapbamrer, R., Lerttrakarnnon, P., & Awiphan, R. (2020) · The Open Public Health Journal · doi:10.2174/1874944502013010815 · Cited by 5
Unpacking the Specific Associations Between Adverse Childhood Experiences and Depressive Symptoms among the Middle-Aged and Elderly Chinese Populations: A Dimensional Approach and Latent Class Analysis in a Cohort Study
Wei, M., Wang, M., Chang, R., Li, C., Xu, K., Jiang, Y., Wang, Y., Tuerxun, P., & Zhang, J. (2023) · Depression and Anxiety · doi:10.1155/2023/8439527 · Cited by 5
Depressionen im höheren Lebensalter, Teil 1: Entstehung, klinische Symptome, Diagnose und Wechselwirkung zwischen Depression und Demenz
Wolter, D. K. (2016) · Zeitschrift für Gerontologie und Geriatrie · Cited by 5
Dynamic interplay of cognitive functioning and depressive symptoms in patients with Parkinson’s disease.
Schroeders, U., Zimmermann, J., Wicke, T., Schaumburg, M., Lang, E., Trenkwalder, C., & Mollenhauer, B. (2022) · Neuropsychology · doi:10.1037/neu0000795 · Cited by 5
Fluctuation of depressive symptoms in cognitively unimpaired participants and the risk of mild cognitive impairment 5 years later: Results of the Heinz Nixdorf Recall study
Jokisch, M., Schramm, S. H., Weimar, C., Moebus, S., Gronewold, J., Dragano, N., & Jöckel, K. (2022) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2022.988621 · Cited by 5
Updates in Vascular Dementia
Eizaguirre, N. O., Rementería, G. P., Torres, M. Á. G., & Gaviria, M. (2017) · Heart and Mind · doi:10.4103/hm.hm_4_16 · Cited by 5
The role of lifestyle factors in primary prevention of dementia
Deckers (2017) · Research Publications (Maastricht University) · doi:10.26481/dis.20170511kd · Cited by 6
Late-Onset Depression in an Aging World: A Multidimensional Perspective on Risks, Mechanisms, and Treatment
D’Onofrio, A. M., Ferrajoli, G. F., Balzoni, L. M., Massetti, M., Zanzarri, A., Marano, G., Mazza, M., Koukopoulos, A. E., Kotzalidis, G. D., Moccia, L., et al. (2026) · Geriatrics · doi:10.3390/geriatrics11010013 · Cited by 4
Depression, Vascular Burden, and Dementia Prevalence in Late Middle-Aged and Older Black Adults
Levy, S.-A. T., Misiura, M. B., Grant, J. G., Adrien, T. V., Taiwo, Z., Armstrong, R., & Dotson, V. M. (2024) · The Journals of Gerontology Series B · doi:10.1093/geronb/gbae009 · Cited by 4
Self-citation
Affective symptoms across the life course and resilience in cognitive function
Bell, G., John, A., & Gaysina, D. (2020) · Annals of Human Biology · doi:10.1080/03014460.2020.1745886 · Cited by 4
Exploring the Impact of Cognitive Dysfunction During Recurrent Depression in a Sample of Mid‐to‐Older Age British South Asians: A Qualitative Study
Akhtar, A., Shafiq, S., Parveen, S., Nwofe, E. S., & Windle, K. (2024) · Journal of Psychiatric and Mental Health Nursing · doi:10.1111/jpm.13113 · Cited by 5
Changes in the distribution of elements in the liver and various brain regions in suicides from southeastern Poland
Baj, J., Forma, A., Karakuła, K. H., Flieger, W., Flieger, M., Kowalska, B., Kamińska, I., Majerek, D., Teresiński, G., Maciejewski, R., et al. (2025) · Scientific Reports · doi:10.1038/s41598-025-03283-2 · Cited by 4
Cognitive Functioning in Late-life Depression: A Critical Review of Sociodemographic, Neurobiological, and Treatment Correlates
Dotson, V. M., Szymkowicz, S. M., Kim, J. U., & McClintock, S. M. (2018) · Current Behavioral Neuroscience Reports · doi:10.1007/s40473-018-0159-4 · Cited by 3
Self-citation
Combining artificial neural networks and a marginal structural model to predict the progression from depression to Alzheimer's disease
Orimaye, S. O., & Schmidtke, K. A. (2024) · Frontiers in Dementia · doi:10.3389/frdem.2024.1362230 · Cited by 3
Experimental laboratory models as tools for understanding modifiable dementia risk
Sinclair, D., Canty, A. J., Ziebell, J. M., Woodhouse, A., Collins, J. M., Perry, S. E., Roccati, E., Kuruvilla, M. V., Leung, J. Y. K., Atkinson, R. A. K., et al. (2024) · Alzheimer s & Dementia · doi:10.1002/alz.13834 · Cited by 2
Depression in Alzheimer's Disease
Kwak, Y. T., Yang, Y., & Koo, M. (2014) · Dementia and Neurocognitive Disorders · doi:10.12779/dnd.2014.13.2.27 · Cited by 3
Psychotherapy for Depression With Executive Dysfunction
Wetherell, J. L. (2010) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2010.10081161 · Cited by 3
Understanding the Bidirectional Relationship between Alzheimer's and Depression
Pannu, A. S., & Goyal, R. K. (2024) · Current Psychiatry Research and Reviews · doi:10.2174/0126660822303361240903075653 · Cited by 4
Electroconvulsive therapy for neuropsychiatric symptoms in a patient with posterior cortical atrophy associated with Alzheimer's disease and a history of depression: A case report and review of the literature
Moyano, B. P., Swierkosz-Lenart, K., Schuster, J., Garcia, N. R. P., Rouaud, O., Vandel, P., & von Gunten, A. (2025) · Psychiatry Research Case Reports · doi:10.1016/j.psycr.2025.100256 · Cited by 2
Relationship among number of close friends, subclinical geriatric depression, and subjective cognitive decline based on regional homogeneity of functional magnetic resonance imaging data
Zhang, Z., Li, G., Song, Z., Han, Y., & Tang, X. (2022) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2022.978611 · Cited by 2
Evaluation of the Influence of Clinical History on the Occurrence of Dementia Using the Database of National Health Insurance in Japan
Tamaki, Y., Hiratsuka, Y., & Kumakawa, T. (2023) · Journal of Ageing and Longevity · doi:10.3390/jal3040025 · Cited by 2
Depression and Dementia in Elderly People
Preçi, G., Zekja, I., Kruja, J., & Abazaj, E. (2022) · Open Access Macedonian Journal of Medical Sciences · doi:10.3889/oamjms.2022.7972 · Cited by 3
Depression, the Metabolic Syndrome and Neurodegeneration
Leonard, B. E. (2015) · Current topics in neurotoxicity · doi:10.1007/978-3-319-13602-8_11 · Cited by 2
Expressed emotion
Leff, J. (2013) · The British Journal of Psychiatry · doi:10.1192/bjp.bp.112.108548 · Cited by 2
Récurrence dépressive chez la personne âgée : quel pronostic cognitif ?
Benoît, M. (2010) · L Encéphale · doi:10.1016/s0013-7006(10)70045-2 · Cited by 2
Treatment opportunities for ameliorating cognitive dysfunction in major depressive disorder
Cha, D. S. (2015) · Cambridge University Press eBooks · doi:10.1017/cbo9781139860567.019 · Cited by 2
Moving Beyond Mood: Is it Time to Recommend Cognitive Training for Depression in Older Adults?
Naismith, S. L., & Mowszowski, L. (2016) · Springer eBooks · doi:10.1007/978-3-319-32480-7_21 · Cited by 2
Facteurs de risque de la maladie d’Alzheimer et des maladies apparentées : approche parcours de vie
Singh‐Manoux, A., & Sabia, S. (2020) · Bulletin de l Académie Nationale de Médecine · doi:10.1016/j.banm.2020.01.015 · Cited by 4
A Single-Case Design Investigation for Measuring the Efficacy of Gestalt Therapy to Treat Depression in Older Adults with Dementia in Italy and in Mexico: A Research Protocol
Merizzi, A., Biasi, R., Zamudio, J. F. Á., Lobb, M. S., Rosa, M. D., & Santini, S. (2022) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph19063260 · Cited by 2
Prevention of dementia by targeting risk factors – Authors' reply
Livingston, G., Sommerlad, A., Schneider, L. S. S., Mukadam, N., & Costafreda, S. G. (2018) · The Lancet · doi:10.1016/s0140-6736(18)30570-1 · Cited by 2
Comparison of Word Reading between Cognitively Normal Elderly and Elderly with Mild Cognitive Impairment according to Word Condition
Lee, S. J., Yeon, E. J., & Yoon, J. H. (2021) · Audiology and Speech Research · doi:10.21848/asr.210003 · Cited by 1
Cognitive Decline and Self Rated Health Among Older Adults in Lebanon
Moubasher, Y., Chaaya, M., Abdulrahim, S., Jaffa, M. A., & Sibai, A. M. (2022) · Lebanese Science Journal · doi:10.22453/lsj-023.1.099-110 · Cited by 1
Organized Registration for the Assessment of Dementia by the Nationwide General Consortium Toward Effective Treatment (ORANGE) Registry: Current Status and Perspectives of Mild Cognitive Impairment
Tsujimoto, M., Suzuki, K., Saji, N., Sakurai, T., Ito, K., Toba, K., & Registry Study Group ORANGE (2022) · Journal of Alzheimer s Disease · doi:10.3233/jad-220039 · Cited by 2
Network models of late life depression symptoms and cognitive impairments across time
Whiston, A., Semkovska, M., Boland, P., Cassidy, I., Cremona, A., Dillon, S., Hayes, S., Kearns, Á., Larkin, E., Tuohy, D., et al. (2025) · Aging & Mental Health · doi:10.1080/13607863.2025.2458075 · Cited by 1

Authors: Dotson, V. M., Beydoun, M. A., & Zonderman, A. B.
Affiliations: National Institutes of Health (US)
ORCID: Dotson, Vonetta M.
Beydoun, May A.
Zonderman, Alan B.
Venue: Neurology
Publisher: Ovid Technologies (Wolters Kluwer Health)
Published: 2010-07-06
Volume: 75
Issue: 1
Pages: 27-34
ISSN: 0028-3878 (ISSN-L)
1526-632X
DOI: 10.1212/wnl.0b013e3181e62124
PMC: PMC2906403
OpenAlex: W2062539816
Cited by: 385
References: 38
Citations by year: 2026: 12 · 2025: 19 · 2024: 26 · 2023: 17 · 2022: 33 · 2021: 31 · 2020: 37 · 2019: 17 · 2018: 19 · 2017: 24 · 2016: 21 · 2015: 26 · 2014: 19 · 2013: 23 · 2012: 28
FWCI: 18.37
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Locations: Neurology (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
Funders: National Institute on Aging (P30AG028740)
Topics: Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
Health Sciences › Medicine › Pharmacology (medical) › Treatment of Major Depression
Health Sciences › Medicine › Oncology › Cancer-related cognitive impairment studies
Keywords: recurrent depression, dementia risk, mild cognitive impairment, Alzheimer's disease, older adults, dose-response relationship, depression recurrence, dementia prevention
MeSH terms: Aged, Aged, 80 and over, Aging, Cognition Disorders, Dementia, Depression, Female, Follow-Up Studies, Humans, Longitudinal Studies, Male, Middle Aged, Prospective Studies, Incidence, Secondary Prevention

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Recurrent depressive symptoms and the incidence of dementia and mild cognitive impairment

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks