Cited by 122Folate and B Vitamins ResearchDementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

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Homocysteine and holotranscobalamin and the risk of Alzheimer disease: A longitudinal study

Hooshmand, B., Solomon, A., Kåreholt, I., Leiviskä, J., Rusanen, M., Ahtiluoto, S., Winblad, B., Laatikainen, T., Soininen, H., Kivipelto, M.·2010·Neurology

DOI 10.1212/wnl.0b013e3181f88162

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Abstract

An investigation has been undertaken to determine the effects of fenfluramine on glucose tolerance, insulin, fasting lipid and lipoprotein levels, in a series of twenty-five patients suffering from peripheral arterial disease. The results indicate that fenfluramine significantly improved glucose tolerance and that this was not the result of increased insulin production. Small but significant reduction in fasting cholesterol and β lipoprotein levels also occurred in most of the patients. Fenfluramine had no consistent effect on fasting nonesterified fatty acid, glycerides or pre-β lipoproteins.

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Authors: Hooshmand, B., Solomon, A., Kåreholt, I., Leiviskä, J., Rusanen, M., Ahtiluoto, S., Winblad, B., Laatikainen, T., Soininen, H., & Kivipelto, M.
Affiliations: University of Eastern Finland (FI)
ORCID: Hooshmand, B.
Solomon, A.
Kåreholt, I.
Winblad, B.
Laatikainen, T.
Soininen, H.
Kivipelto, M.
Venue: Neurology
Publisher: Ovid Technologies (Wolters Kluwer Health)
Published: 2010-10-19
Volume: 75
Issue: 16
Pages: 1408-1414
ISSN: 0028-3878 (ISSN-L)
1526-632X
DOI: 10.1212/wnl.0b013e3181f88162
OpenAlex: W1979444541
Cited by: 122
References: 43
Citations by year: 2026: 2 · 2025: 6 · 2024: 5 · 2023: 2 · 2022: 6 · 2021: 7 · 2020: 5 · 2019: 10 · 2018: 8 · 2017: 5 · 2016: 10 · 2015: 10 · 2014: 10 · 2013: 11 · 2012: 13
FWCI: 8.04
Type: journal article
Language: en
Open access: closed
Locations: Neurology (publishedVersion)
Topics: Health Sciences › Nursing › Nutrition and Dietetics › Folate and B Vitamins Research
Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Alzheimer's disease research and treatments
Keywords: homocysteine, holotranscobalamin, Alzheimer's disease, fenfluramine, glucose tolerance, insulin, peripheral arterial disease, fasting lipids, cholesterol, low-density lipoprotein, free fatty acids

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Homocysteine and holotranscobalamin and the risk of Alzheimer disease: A longitudinal study

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