Understanding the cause of sporadic Alzheimer’s disease

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Alzheimer's disease: the amyloid cascade hypothesis

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Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade

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Phases of Aβ-deposition in the human brain and its relevance for the development of AD

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Apolipoprotein E and Alzheimer disease: risk, mechanisms and therapy

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Identification of a specific telomere terminal transferase activity in tetrahymena extracts

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Alzheimer’s disease

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<i>TREM2</i> Variants in Alzheimer's Disease

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Regional Brain Changes in Aging Healthy Adults: General Trends, Individual Differences and Modifiers

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Alzheimer disease in the United States (2010–2050) estimated using the 2010 census

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Variant of <i>TREM2</i> Associated with the Risk of Alzheimer's Disease

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Amyloid deposition as the central event in the aetiology of Alzheimer’s disease

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Observations on the brains of demented old people

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Mixed brain pathologies account for most dementia cases in community-dwelling older persons

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Two Phase 3 Trials of Bapineuzumab in Mild-to-Moderate Alzheimer's Disease

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The Pathobiology of Vascular Dementia

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A mutation in APP protects against Alzheimer’s disease and age-related cognitive decline

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Phase 3 Trials of Solanezumab for Mild-to-Moderate Alzheimer's Disease

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Frequency of Stages of Alzheimer-Related Lesions in Different Age Categories

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Human ApoE isoforms differentially regulate brain amyloid-β peptide clearance

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A Phase 3 Trial of Semagacestat for Treatment of Alzheimer's Disease

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Alzheimer disease: Epidemiology, diagnostic criteria, risk factors and biomarkers

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A two-decade comparison of prevalence of dementia in individuals aged 65 years and older from three geographical areas of England: results of the Cognitive Function and Ageing Study I and II

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[ ¹¹ C]PIB in a nondemented population: Potential antecedent marker of Alzheimer disease

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11C PiB and structural MRI provide complementary information in imaging of Alzheimer's disease and amnestic mild cognitive impairment

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The neuropathology of probable Alzheimer disease and mild cognitive impairment

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<i>APOE</i> predicts amyloid‐beta but not tau Alzheimer pathology in cognitively normal aging

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The pathological process underlying Alzheimer’s disease in individuals under thirty

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Fibrillar amyloid-β burden in cognitively normal people at 3 levels of genetic risk for Alzheimer's disease

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apoE isoform–specific disruption of amyloid β peptide clearance from mouse brain

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One-Year Brain Atrophy Evident in Healthy Aging

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Episodic memory loss is related to hippocampal-mediated -amyloid deposition in elderly subjects

Mormino, E. C., Kluth, J. T., Madison, C. M., Rabinovici, G. D., Baker, S. L., Miller, B. L., Koeppe, R. A., Mathis, C. A., Weiner, M. W., Jagust, W. J., et al. (2009) · Brain · doi:10.1093/brain/awn320 · Cited by 684 · see citing works

Cerebrospinal Fluid Levels ofβ-Amyloid 1-42, but Not of Tau, Are Fully Changed Already 5 to 10 Years Before the Onset of Alzheimer Dementia

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Apolipoprotein E (APOE) allele distribution in the world. Is APOE*4 a ‘thrifty’ allele?

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Clinical, genetic, and neuropathologic characteristics of posterior cortical atrophy

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Genetic evidence implicates the immune system and cholesterol metabolism in the aetiology of Alzheimer’s disease

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Posterior cortical atrophy

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Preclinical Alzheimer's disease and its outcome: a longitudinal cohort study

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Amyloidosis

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Midlife Serum Cholesterol and Increased Risk of Alzheimer’s and Vascular Dementia Three Decades Later

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The mechanism of γ‐Secretase dysfunction in familial Alzheimer disease

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Clinicopathological correlations in corticobasal degeneration

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Clinical and Pathological Evidence for a Frontal Variant of Alzheimer Disease

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Primary progressive aphasia: clinicopathological correlations

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Two faces of p53: aging and tumor suppression

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CSF biomarker variability in the Alzheimer's Association quality control program

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Relationship between atrophy and β‐amyloid deposition in Alzheimer disease

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Vascular risk factors promote conversion from mild cognitive impairment to Alzheimer disease

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Diverging patterns of amyloid deposition and hypometabolism in clinical variants of probable Alzheimer's disease

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Rare variants in APP, PSEN1 and PSEN2 increase risk for AD in late-onset Alzheimer’s disease families

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Twenty-year changes in dementia occurrence suggest decreasing incidence in central Stockholm, Sweden

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Cognitive decline is faster in Lewy body variant than in Alzheimer's disease

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Human<i>APOE</i>Isoform-Dependent Effects on Brain β-Amyloid Levels in PDAPP Transgenic Mice

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Brain Differences in Infants at Differential Genetic Risk for Late-Onset Alzheimer Disease: A Cross-sectional Imaging Study

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Generation of amyloid β protein from its precursor is sequence specific

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Clinical syndromes associated with posterior atrophy

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The up‐regulation of BACE1 mediated by hypoxia and ischemic injury: role of oxidative stress and HIF1α

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Meta-Analysis of APOE 4 Allele and Outcome after Traumatic Brain Injury

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Plaque-Only Alzheimer Disease is Usually the Lewy Body Variant, and Vice Versa

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Brain Changes in Older Adults at Very Low Risk for Alzheimer's Disease

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Political drive to screen for pre-dementia: not evidence based and ignores the harms of diagnosis

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Cerebrospinal fluid -amyloid 1-42 concentration may predict cognitive decline in older women

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CSF Biomarkers in Prediction of Cerebral and Clinical Change in Mild Cognitive Impairment and Alzheimer's Disease

Fjell, A. M., Walhovd, K. B., Fennema‐Notestine, C., McEvoy, L. K., Hagler, D. J., Holland, D., Brewer, J. B., Dale, A. M., & Initiative, A. D. N. (2010) · Journal of Neuroscience · doi:10.1523/jneurosci.3785-09.2010 · Cited by 209 · see citing works

Amyloid-first and neurodegeneration-first profiles characterize incident amyloid PET positivity

Jack, C. R., Wiste, H. J., Weigand, S. D., Knopman, D. S., Lowe, V. J., Vemuri, P., Mielke, M. M., Jones, D. T., Senjem, M. L., Gunter, J. L., et al. (2013) · Neurology · doi:10.1212/01.wnl.0000435556.21319.e4 · Cited by 200 · see citing works

Dementia From Alzheimer Disease and Mixed Pathologies in the Oldest Old

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The paradox of syndromic diversity in Alzheimer disease

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Brain injury biomarkers are not dependent on β‐amyloid in normal elderly

Knopman, D. S., Jack, C. R., Wiste, H. J., Weigand, S. D., Vemuri, P., Lowe, V. J., Kantarci, K., Gunter, J. L., Senjem, M. L., Mielke, M. M., et al. (2013) · Annals of Neurology · doi:10.1002/ana.23816 · Cited by 183 · see citing works

Deciphering logopenic primary progressive aphasia: a clinical, imaging and biomarker investigation

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Hypoxia Due to Cardiac Arrest Induces a Time-Dependent Increase in Serum Amyloid β Levels in Humans

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Accelerated cortical atrophy in cognitively normal elderly with high β-amyloid deposition

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Associations Between Alzheimer Disease Biomarkers, Neurodegeneration, and Cognition in Cognitively Normal Older People

Wirth, M., Villeneuve, S., Haase, C. M., Madison, C. M., Oh, H., Landau, S. M., Rabinovici, G. D., & Jagust, W. J. (2013) · JAMA Neurology · doi:10.1001/jamaneurol.2013.4013 · Cited by 171 · see citing works

Clinical and multimodal biomarker correlates of ADNI neuropathological findings

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Apolipoprotein E, not fibrillar β-amyloid, reduces cerebral glucose metabolism in normal aging

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Larger temporal volume in elderly with high versus low beta-amyloid deposition

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Amyloid Imaging With Carbon 11–Labeled Pittsburgh Compound B for Traumatic Brain Injury

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TDP-43 pathological changes in early onset familial and sporadic Alzheimer’s disease, late onset Alzheimer’s disease and Down’s Syndrome: association with age, hippocampal sclerosis and clinical phenotype

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Common Variants in Psychiatric Risk Genes Predict Brain Structure at Birth

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Revision of the apolipoprotein E compensatory mechanism recruitment hypothesis

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Increased brain atrophy rates in cognitively normal older adults with low cerebrospinal fluid Aβ1‐42

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Anatomically-distinct genetic associations of APOE ɛ4 allele load with regional cortical atrophy in Alzheimer's disease

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Dominantly Inherited Alzheimer Network: facilitating research and clinical trials

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