Epidemiology of amyotrophic lateral sclerosis: 1. A case‐control comparison based on ALS deaths
Abstract
Deaths coded to amyotrophic lateral sclerosis (ALS) for the years 1963 to 1967 among U.S. males were matched against military files to identify 504 World War II veterans. Military controls for these 504 men were matched for year of birth, date of entry into military service, and branch of service. Hospital records of 37 representative deaths coded as ALS among veterans were reviewed, and 36 were accepted as definite ALS. Military records were abstracted for information about preservice demographic and other factors, the physical examination for entry into service, and the medical history and factors characterizing the military career during World War II. There was a deficit of blacks with ALS, which did not attain statistical significance (p = 0.08). Several differences in preservice occupations were found: Truck drivers and “operatives” were in excess. There was no significant difference between ALS cases and controls in aggregate scores on sports activity before service, although baseball was more often listed by the ALS cases than by controls. The ALS patients significantly more often gave histories of trauma or surgical operations before service, and during service had a significant excess of hospitalizations for trauma and in particular for fractures of the limbs.
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Sport participation has been supposed a risk factor for ALS since at least the 1970s.
“Although sport participation has been supposed a risk factor for ALS since at least the 1970s (Kurtzke and Beebe, 1980)”
From Severely increased risk of amyotrophic lateral sclerosis among Italian professional football players (2005) · cites this paper as Kurtzke and Beebe, 1980
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- Authors
- Kurtzke, J. F., & Beebe, G. W.
- Affiliations
- Departments of Neurology and Community Medicine. Georgetown University School of Medicine, and the Neurology Service, Veterans Administration Medical Center, Washington, DC (Dr. Kurtzke), and the Medical Follow-up Agency, National Academy of sciences-National Research Council, Washington, DC (Dr. Beebe).
- Venue
- Neurology
- Published
- 1980-05
- Volume
- 30
- Issue
- 5
- Pages
- 453-453
- ISSN
- 0028-3878
- 1526-632X
- Cited by
- 107
- References
- 0
- Language
- en
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