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Liver organoid culture methods

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Generation of Budding-Like Intestinal Organoids from Human Induced Pluripotent Stem Cells

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Spheres of Influence: Insights into Salmonella Pathogenesis from Intestinal Organoids

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Examining the Characteristics and Applications of Mesenchymal, Induced Pluripotent, and Embryonic Stem Cells for Tissue Engineering Approaches across the Germ Layers

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Building gut from scratch — progress and update of intestinal tissue engineering

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Inflammatory Bowel Disease: Pathophysiology, Treatment, and Disease Modeling

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Advances in the Development and Application of Human Organoids: Techniques, Applications, and Future Perspectives

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Farm Animal-derived Models of the Intestinal Epithelium: Recent Advances and Future Applications of Intestinal Organoids

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Engineering mechanobiology through organoids‐on‐chip: A strategy to boost therapeutics

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Tissue engineering of the gastrointestinal tract: the historic path to translation

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LGR4 and LGR5 Function Redundantly During Human Endoderm Differentiation

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Composite Scaffolds Based on Intestinal Extracellular Matrices and Oxidized Polyvinyl Alcohol: A Preliminary Study for a New Regenerative Approach in Short Bowel Syndrome

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Taming the Wild West of Organoids, Enteroids, and Mini-Guts

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Towards better models and mechanistic biomarkers for drug-induced gastrointestinal injury

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From Static to Dynamic: A Review on the Role of Mucus Heterogeneity in Particle and Microbial Transport

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Synergistic modulation of signaling pathways to expand and maintain the bipotency of human hepatoblasts

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Regenerative medicine technologies applied to transplant medicine. An update

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Spray Delivery of Intestinal Organoids to Reconstitute Epithelium on Decellularized Native Extracellular Matrix

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A Comparison of Sterilization Techniques for Production of Decellularized Intestine in Mice

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Stem Cell-Derived Models of Viral Infections in the Gastrointestinal Tract

Lanik, W. E., Mara, M., Mihi, B., Coyne, C. B., & Good, M. L. (2018) · Viruses · doi:10.3390/v10030124 · Cited by 18

Patient‐derived organoid culture in epithelial ovarian cancers—Techniques, applications, and future perspectives

Chan, W. S., Mo, X.-T., Ip, P. P. C., & Tse, K. Y. (2023) · Cancer Medicine · doi:10.1002/cam4.6521 · Cited by 20

Intestinal organoids: roadmap to the clinic

Kasendra, M. J., Troutt, M. L., Broda, T. R., Bacon, W. C., Wang, T. C., Niland, J. C., & Helmrath, M. A. (2021) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00425.2020 · Cited by 18

Induced pluripotent stem cells for disease modeling, cell therapy and drug discovery in genetic autonomic disorders: a review

Saito‐Diaz, K., & Zeltner, N. (2019) · Clinical Autonomic Research · doi:10.1007/s10286-018-00587-4 · Cited by 18

Chromatin regulatory dynamics of early human small intestinal development using a directed differentiation model

Hung, Y.-H., Huang, S., Dame, M. K., Yu, Q., Yu, Q. C., Zeng, Y. A., Camp, J. G., Spence, J. R., & Sethupathy, P. (2020) · Nucleic Acids Research · doi:10.1093/nar/gkaa1204 · Cited by 18

Materials and Microenvironments for Engineering the Intestinal Epithelium

Snyder, J. R., Wang, C.-M., Zhang, A. Q., Li, Y., Luchan, J., Hosic, S., Koppes, R. A., Carrier, R. L., & Koppes, A. N. (2020) · Annals of Biomedical Engineering · doi:10.1007/s10439-020-02470-8 · Cited by 19

Induced pluripotent stem cell-derived enteric neural crest cells repopulate human aganglionic tissue-engineered intestine to form key components of the enteric nervous system

Chang, D. F., Zuber, S. M., Gilliam, E. A., Nucho, L.-M. A., Levin, G., Wang, F., Squillaro, A. I., Huang, S., Spence, J. R., & Grikscheit, T. C. (2020) · Journal of Tissue Engineering · doi:10.1177/2041731420905701 · Cited by 15

Focus on organoids: cooperation and interconnection with extracellular vesicles – Is this the future of in vitro modeling?

Jurj, A. M., Paşca, S., Braicu, C., Rusu, I., Korban, S. S., & Berindan‐Neagoe, I. (2021) · Seminars in Cancer Biology · doi:10.1016/j.semcancer.2021.12.002 · Cited by 15

Bioengineering toolkits for potentiating organoid therapeutics

Park, S., & Cho, S. (2024) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2024.115238 · Cited by 18

Engineering the Future of Regenerative Medicines in Gut Health with Stem Cell-Derived Intestinal Organoids

Kumar, D., Gupta, S., Gupta, V., Tanwar, R., & Chandel, A. (2025) · Stem Cell Reviews and Reports · doi:10.1007/s12015-025-10893-w · Cited by 17

Tissue Engineering for Gastrointestinal and Genitourinary Tracts

Elia, E., Brownell, D., Chabaud, S., & Bolduc, S. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms24010009 · Cited by 13

R-Spondin 1 (RSPO1) Increases Mouse Intestinal Organoid Unit Size and Survival in vitro and Improves Tissue-Engineered Small Intestine Formation in vivo

Levin, G., Zuber, S. M., Squillaro, A. I., Sogayar, M. C., Grikscheit, T. C., & Carreira, A. C. O. (2020) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2020.00476 · Cited by 14

Combating COVID-19 with tissue engineering: a review

Aydin, A., Çebi, G., Demirtas, Z. E., Erkus, H., Kucukay, A., Ok, M., Sakalli, L., Alpdağtaş, S., Gündüz, O., & Üstündağ, C. B. (2020) · Emergent Materials · doi:10.1007/s42247-020-00138-6 · Cited by 13

Plumbing our organs: Lessons from vascular development to instruct lab generated tissues

Ryan, A. R., & Cleaver, O. B. (2022) · Current topics in developmental biology/Current Topics in Developmental Biology · doi:10.1016/bs.ctdb.2022.02.013 · Cited by 12

Advancing intestinal organoid technology to decipher nano-intestine interactions and treat intestinal disease

Bao, L., Cui, X., Bai, R., & Chen, C. (2022) · Nano Research · doi:10.1007/s12274-022-5150-4 · Cited by 12

Using 3D Organoid Cultures to Model Intestinal Physiology and Colorectal Cancer

Short, S. P., Costacurta, P. W., & Williams, C. S. (2017) · Current Colorectal Cancer Reports · doi:10.1007/s11888-017-0363-8 · Cited by 14

Short‐term and long‐term human or mouse organoid units generate tissue‐engineered small intestine without added signalling molecules

Hou, X., Chang, D. F., Trecartin, A., Barthel, E. R., Schlieve, C. R., Frey, M. R., Fowler, K. L., & Grikscheit, T. C. (2018) · Experimental Physiology · doi:10.1113/ep086990 · Cited by 13

An in vivo model of human small intestine using pluripotent stem cells

Watson, C. L., Mahé, M. M., Múnera, J. O., Howell, J. C., Sundaram, N., Poling, H. M., Schweitzer, J. I., Vallance, J. E., Mayhew, C. N., Sun, Y., et al. (2014) · Nature Medicine · doi:10.1038/nm.3737 · Cited by 561

Short Bowel Syndrome and Tissue Engineering: a preliminary study towards the development of a new regenerative approach in paediatric patients

Stocco, E., Porzionato, A., Grandi, F., Barbon, S., Macchi, V., Rambaldo, A., Contran, M., Gamba, P., Parnigotto, P. P., Caro, R. D., et al. (2017) · Italian Journal of Anatomy and Embryology · doi:10.36253/ijae-2105

Human tissue-engineered small intestine forms from postnatal progenitor cells

Levin, D. E., Barthel, E. R., Speer, A. L., Sala, F. G., Hou, X., Torashima, Y., & Grikscheit, T. C. (2013) · Journal of Pediatric Surgery · doi:10.1016/j.jpedsurg.2012.10.029 · Cited by 76

In Vivo Model of Small Intestine

Mahé, M. M., Brown, N. E., Poling, H. M., & Helmrath, M. A. (2017) · Methods in molecular biology · doi:10.1007/978-1-4939-6949-4_17 · Cited by 24

Human pluripotent stem cell-derived organoids repair damaged bowel in vivo

Poling, H. M., Sundaram, N., Fisher, G. W., Singh, A., Shiley, J. R., Nattamai, K., Govindarajah, V., Cortez, A. R., Krutko, M., Ménoret, S., et al. (2024) · Cell stem cell · doi:10.1016/j.stem.2024.08.009 · Cited by 28