The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Shaping the zebrafish notochord
Open accessAbstract
Promptly after the notochord domain is specified in the vertebrate dorsal mesoderm, it undergoes dramatic morphogenesis. Beginning during gastrulation,convergence and extension movements change a squat cellular array into a narrow, elongated one that defines the primary axis of the embryo. Convergence and extension might be coupled by a highly organized cellular intermixing known as mediolateral intercalation behavior (MIB). To learn whether MIB drives early morphogenesis of the zebrafish notochord, we made 4D recordings and quantitatively analyzed both local cellular interactions and global changes in the shape of the dorsal mesodermal field. We show that MIB appears to mediate convergence and can account for extension throughout the dorsal mesoderm. Comparing the notochord and adjacent somitic mesoderm reveals that extension can be regulated separately from convergence. Moreover, mutational analysis shows that extension does not require convergence. Hence, a cellular machine separate from MIB that can drive dorsal mesodermal extension exists in the zebrafish gastrula. The likely redundant control of morphogenesis may provide for plasticity at this critical stage of early development.
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Citations
Cites
Silberblick/Wnt11 mediates convergent extension movements during zebrafish gastrulation
Heisenberg, C.-P., Tada, M., Rauch, G.-J., Saúde, L., Concha, M. L., Geisler, R., Stemple, D. L., Smith, J. C., & Wilson, S. W. (2000) · Nature · doi:10.1038/35011068 · Cited by 1,013
Dishevelled controls cell polarity during Xenopus gastrulation
Wallingford, J. B., Rowning, B. A., Vogeli, K. M., Rothbächer, U., Fraser, S. E., & Harland, R. M. (2000) · Nature · doi:10.1038/35011077 · Cited by 751
A homeobox gene essential for zebrafish notochord development
Talbot, W. S., Trevarrow, B., Halpern, M. E., Melby, A. E., Farr, G., Postlethwait, J. H., Jowett, T., Kimmel, C. B., & Kimelman, D. (1995) · Nature · doi:10.1038/378150a0 · Cited by 465 · cited 2×
“The notochord domain is about 20 cells wide in the early gastrula (as determined from expression of the Not gene floating headat 6 hpf) (see Melby et al., 1996; Talbot et al., 1995).”
BackgroundSelf-citation
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Frizzled/PCP signalling: a conserved mechanism regulating cell polarity and directed motility
Seifert, J. R. K., & Mlodzik, M. (2007) · Nature Reviews Genetics · doi:10.1038/nrg2042 · Cited by 513
How we are shaped: The biomechanics of gastrulation
Keller, R., Davidson, L. A., & Shook, D. R. (2003) · Differentiation · doi:10.1046/j.1432-0436.2003.710301.x · Cited by 494
Conserved Patterns of Cell Movements during Vertebrate Gastrulation
Solnica-Krezel, L. (2005) · Current Biology · doi:10.1016/j.cub.2005.03.016 · Cited by 391
Tissue tectonics: morphogenetic strain rates, cell shape change and intercalation
Blanchard, G. B., Kabla, A. J., Schultz, N. L., Butler, L. C., Sanson, B., Gorfinkiel, N., Mahadevan, L., & Adams, R. J. (2009) · Nature Methods · doi:10.1038/nmeth.1327 · Cited by 302
Self-citationThe amniote primitive streak is defined by epithelial cell intercalation before gastrulation
Voiculescu, O., Bertocchini, F., Wolpert, L., Keller, R. E., & Stern, C. D. (2007) · Nature · doi:10.1038/nature06211 · Cited by 261
Development of the annelid axochord: Insights into notochord evolution
Lauri, A., Brunet, T., Handberg-Thorsager, M., Fischer, A. H. L., Simakov, O., Steinmetz, P. R. H., Tomer, R., Keller, P. J., & Arendt, D. (2014) · Science · doi:10.1126/science.1253396 · Cited by 104
Weiser, D. C., Pyati, U. J., & Kimelman, D. (2007) · Genes & Development · doi:10.1101/gad.1535007 · Cited by 62
Spatiotemporal resolution of the Ntla transcriptome in axial mesoderm development
Shestopalov, I. A., Pitt, C. L. W., & Chen, J. K. (2012) · Nature Chemical Biology · doi:10.1038/nchembio.772 · Cited by 42
Gag proteins encoded by endogenous retroviruses are required for zebrafish development
Chang, N.-C., Wells, J. N., Wang, A. Y., Schofield, P., Huang, Y.-C., Truong, V. H., Simoes-Costa, M., & Feschotte, C. (2025) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2411446122 · Cited by 27
Metadata
- Authors
- Glickman, N. S., Kimmel, C. B., Jones, M. A., & Adams, R. J.
- Venue
- Development
- Publisher
- The Company of Biologists
- Published
- 2003-03-01
- Volume
- 130
- Issue
- 5
- Pages
- 873-887
- ISSN
- 0950-1991 (ISSN-L)
- 1477-9129
- OpenAlex
- W2085966480
- Cited by
- 216
- References
- 3
- FWCI
- 4.93
- Type
- journal article
- Language
- en
- Open access
- bronze
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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