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Cited by 185

The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.

β-Catenin regulates Cripto- and Wnt3-dependent gene expression programs in mouse axis and mesoderm formation

Open access
Morkel, Markus, Huelsken, Joerg, Wakamiya, Maki, Ding, Jixiang, van de Wetering, Marc, Clevers, Hans, Taketo, Makoto M., Behringer, Richard R., Shen, Michael M., Birchmeier, Walter·2003·Development

Abstract

Gene expression profiling of β-catenin, Cripto and Wnt3 mutant mouse embryos has been used to characterise the genetic networks that regulate early embryonic development. We have defined genes whose expression is regulated by β-catenin during formation of the anteroposterior axis and the mesoderm, and have identified Cripto,which encodes a Nodal co-receptor, as a primary target of β-catenin signals both in embryogenesis as well as in colon carcinoma cell lines and tissues. We have also defined groups of genes regulated by Wnt3/β-catenin signalling during primitive streak and mesoderm formation. Our data assign a key role to β-catenin upstream of two distinct gene expression programs during anteroposterior axis and mesoderm formation.

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Registry

Crossref · 10.1242/dev.00859

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Metadata

Authors
Morkel, M., Huelsken, J., Wakamiya, M., Ding, J., van de Wetering, M., Clevers, H., Taketo, M. M., Behringer, R. R., Shen, M. M., & Birchmeier, W.
Venue
Development
Published
2003-12-22
Volume
130
Issue
25
Pages
6283-6294
ISSN
  • 0950-1991 (ISSN-L)
  • 1477-9129
OpenAlex
W2132488261
Cited by
185
References
7
FWCI
3.65
Type
journal article
Language
en
Open access
green

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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