Functions of heparan sulfate proteoglycans in cell signaling during development

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QSulf1 remodels the 6-O sulfation states of cell surface heparan sulfate proteoglycans to promote Wnt signaling

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The cell-surface proteoglycan Dally regulates Wingless signalling in Drosophila

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Crystal structure of human bone morphogenetic protein-2 at 2.7 Å resolution 1 1Edited by R. Huber

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Heparan sulfate proteoglycan as a plasma membrane carrier

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Glycosaminoglycans can modulate extracellular localization of the wingless protein and promote signal transduction.

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Structural Analysis of Glycosaminoglycans inDrosophila and Caenorhabditis elegans and Demonstration That tout-velu, a Drosophila Gene Related to EXT Tumor Suppressors, Affects Heparan Sulfate in Vivo

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ThreeDrosophilaEXT genes shape morphogen gradients through synthesis of heparan sulfate proteoglycans

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Loss of HSulf-1 Up-regulates Heparin-binding Growth Factor Signaling in Cancer

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dally, a Drosophila glypican, controls cellular responses to the TGF-β-related morphogen, Dpp

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Drosophila glypicans control the cell-to-cell movement of Hedgehog by a dynamin-independent process

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Distinct and collaborative roles ofDrosophilaEXT family proteins in morphogen signalling and gradient formation

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Targeted Disruption of a Murine Glucuronyl C5-epimerase Gene Results in Heparan Sulfate Lacking l-Iduronic Acid and in Neonatal Lethality

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Dally regulates Dpp morphogen gradient formation in the Drosophila wing

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Heparan Sulfate Proteoglycan Syndecan Promotes Axonal and Myotube Guidance by Slit/Robo Signaling

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QSulf1, a heparan sulfate 6- O -endosulfatase, inhibits fibroblast growth factor signaling in mesoderm induction and angiogenesis

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Defects in glucuronate biosynthesis disrupt Wingless signaling in Drosophila

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The Molecular Phenotype of Heparan Sulfate in theHs2st−/− Mutant Mouse

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Shaping Morphogen Gradients

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Drosophila Perlecan modulates FGF and Hedgehog signals to activate neural stem cell division

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Spatial Regulation of Wingless Morphogen Distribution and Signaling by Dally-like Protein

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Heparan sulfate proteoglycan modulation of developmental signaling in Drosophila

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The glypican Dally-like is required for Hedgehog signalling in the embryonic epidermis ofDrosophila

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The role of glypicans in mammalian development

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Essential Role of Glycosaminoglycans in Fgf Signaling during Mouse Gastrulation

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Wingful, an extracellular feedback inhibitor of WinglessPreprint

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Perlecan participates in proliferation activation of quiescent Drosophila neuroblasts

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UDP–sugar transporter implicated in glycosylation and processing of Notch

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Drosophila Heparan Sulfate 6-O-Sulfotransferase (dHS6ST) Gene

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Dual role of the fringe connection gene in both heparan sulphate and fringe-dependent signalling events

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Creation of a Sog Morphogen Gradient in the Drosophila Embryo

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Producing Cells Retain and Recycle Wingless in Drosophila Embryos

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Cholesterol modification of Hedgehog family proteins

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Identification of a novel nonlysosomal sulphatase expressed in the floor plate, choroid plexus and cartilage

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Cholesterol modification of Hedgehog family proteins

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Mechanisms Underlying Preferential Assembly of Heparan Sulfate on Glypican-1

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Glypican 4 modulates FGF signalling and regulates dorsoventral forebrain patterning inXenopusembryos

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slalom encodes an adenosine 3′‐phosphate 5′‐phosphosulfate transporter essential for development in Drosophila

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