The DOI matches its Crossref record; 159 of the 159 references it cites were found in a registry or an index.
Pancreas and beta-cell development: from the actual to the possible
Abstract
The development of insulin-producing pancreatic beta (β)-cells represents the culmination of a complex developmental program. Cells of the posterior foregut assume a pancreatic identity, cells within the expanding pancreatic primordia adopt an endocrine fate, and a subset of these precursors becomes competent to generate β-cells. Postnatally, β-cells are primarily maintained by self-duplication rather than new differentiation. Although major gaps in our knowledge still persist, experiments across several organisms have shed increasing light on the steps of β-cell specification and differentiation. Increasing our understanding of the extrinsic, as well as intrinsic, mechanisms that control these processes should facilitate efforts to regenerate this important cell type in humans.
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Cites
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Cited by
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Vertebrate Endoderm Development and Organ Formation
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Development of the Human Pancreas From Foregut to Endocrine Commitment
Jennings, R. E., Berry, A. A., Kirkwood-Wilson, R., Roberts, N. A., Hearn, T., Salisbury, R. J., Blaylock, J., Piper Hanley, K., & Hanley, N. A. (2013) · Diabetes · doi:10.2337/db12-1479 · Cited by 310
Genetic programming of liver and pancreas progenitors: lessons for stem-cell differentiation
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Metadata
- Authors
- Murtaugh, L. C.
- Venue
- Development
- Publisher
- The Company of Biologists
- Published
- 2007-02-01
- Volume
- 134
- Issue
- 3
- Pages
- 427-438
- ISSN
- 0950-1991 (ISSN-L)
- 1477-9129
- OpenAlex
- W2091152603
- Cited by
- 289
- References
- 159
- FWCI
- 24.31
- Type
- journal article
- Language
- en
- Open access
- closed
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- Murtaugh, L. C. (2007). Pancreas and beta-cell development: from the actual to the possible. Development. https://doi.org/10.1242/dev.02770
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
