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Cited by 257

The DOI matches its Crossref record; 132 of the 132 references it cites were found in a registry or an index.

Maintaining embryonic stem cell pluripotency with Wnt signaling

Open access
Sokol, Sergei Y.·2011·Development

Abstract

Wnt signaling pathways control lineage specification in vertebrate embryos and regulate pluripotency in embryonic stem (ES) cells, but how the balance between progenitor self-renewal and differentiation is achieved during axis specification and tissue patterning remains highly controversial. The context- and stage-specific effects of the different Wnt pathways produce complex and sometimes opposite outcomes that help to generate embryonic cell diversity. Although the results of recent studies of the Wnt/β-catenin pathway in ES cells appear to be surprising and controversial, they converge on the same conserved mechanism that leads to the inactivation of TCF3-mediated repression.

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Metadata

Authors
Sokol, S. Y.
Venue
Development
Published
2011-10-15
Volume
138
Issue
20
Pages
4341-4350
ISSN
  • 0950-1991 (ISSN-L)
  • 1477-9129
OpenAlex
W2153004457
Cited by
257
References
132
FWCI
8.70
Type
journal article
Language
en
Open access
bronze

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