Mitotic and mitogenic Wnt signalling

Wnt/β-Catenin Signaling: Components, Mechanisms, and Diseases

MacDonald, B. T., Tamai, K., & He, X. (2009) · Developmental Cell · doi:10.1016/j.devcel.2009.06.016 · Cited by 5,583 · see citing works

Wnt/β-Catenin Signaling in Development and Disease

Clevers, H. (2006) · Cell · doi:10.1016/j.cell.2006.10.018 · Cited by 5,568 · see citing works

Identification of c- <i>MYC</i> as a Target of the APC Pathway

He, T.-C., Sparks, A. B., Rago, C., Hermeking, H., Zawel, L., da Costa, L. T., Morin, P. J., Vogelstein, B., & Kinzler, K. W. (1998) · Science · doi:10.1126/science.281.5382.1509 · Cited by 4,566 · see citing works

Activation of β-Catenin-Tcf Signaling in Colon Cancer by Mutations in β-Catenin or APC

Morin, P. J., Sparks, A. B., Kořínek, V., Barker, N., Clevers, H. C., Vogelstein, B., & Kinzler, K. W. (1997) · Science · doi:10.1126/science.275.5307.1787 · Cited by 3,983 · see citing works

Cell cycle, CDKs and cancer: a changing paradigm

Malumbres, M., & Barbacid, M. (2009) · Nature Reviews Cancer · doi:10.1038/nrc2602 · Cited by 3,957 · cited 5× · see citing works

Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology.

Grundke-Iqbal, I., Iqbal, K., Tung, Y. C., Quinlan, M., Wisniewski, H. M., & Binder, L. I. (1986) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.83.13.4913 · Cited by 3,676 · see citing works

Wnt signalling in stem cells and cancer

Reya, T., & Clevers, H. (2005) · Nature · doi:10.1038/nature03319 · Cited by 3,666 · see citing works

β-Catenin regulates expression of cyclin D1 in colon carcinoma cells

Tetsu, O., & McCormick, F. (1999) · Nature · doi:10.1038/18884 · Cited by 3,601 · see citing works

The ground state of embryonic stem cell self-renewal

Ying, Q.-L., Wray, J., Nichols, J., Batlle-Morera, L., Doble, B., Woodgett, J., Cohen, P., & Smith, A. (2008) · Nature · doi:10.1038/nature06968 · Cited by 3,442 · see citing works

β‐catenin is a target for the ubiquitin–proteasome pathway

Aberle, H., Bauer, A., Stappert, J., Kispert, A., & Kemler, R. (1997) · The EMBO Journal · doi:10.1093/emboj/16.13.3797 · Cited by 2,533 · see citing works

Integration of External Signaling Pathways with the Core Transcriptional Network in Embryonic Stem Cells

Chen, X., Han, X., Yuan, P., Fang, F., Huss, M., Vega, V. B., Wong, E., Orlov, Y. L., Zhang, W., Jiang, J., et al. (2008) · Cell · doi:10.1016/j.cell.2008.04.043 · Cited by 2,474 · see citing works

The cyclin D1 gene is a target of the β-catenin/LEF-1 pathway

Shtutman, M., Zhurinsky, J., Simcha, I., Albanese, C., D’Amico, M., Pestell, R., & Ben-Ze’ev, A. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.10.5522 · Cited by 2,230 · see citing works

p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21.

Toyoshima, H., & Hunter, T. (1994) · Cell · doi:10.1016/0092-8674(94)90573-8 · Cited by 2,208 · see citing works

A role for Wnt signalling in self-renewal of haematopoietic stem cells

Reya, T., Duncan, A. W., Ailles, L., Domen, J., Scherer, D. C., Willert, K., Hintz, L., Nusse, R., & Weissman, I. L. (2003) · Nature · doi:10.1038/nature01593 · Cited by 2,159 · see citing works

Glycogen synthase kinase-3β regulates cyclin D1 proteolysis and subcellular localization

Diehl, J. A., Cheng, M., Roussel, M. F., & Sherr, C. J. (1998) · Genes &amp; Development · doi:10.1101/gad.12.22.3499 · Cited by 2,130 · see citing works

Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor

Sato, N., Meijer, L., Skaltsounis, A., Greengard, P., & Brivanlou, A. H. (2003) · Nature Medicine · doi:10.1038/nm979 · Cited by 2,107 · see citing works

The β-Catenin/TCF-4 Complex Imposes a Crypt Progenitor Phenotype on Colorectal Cancer Cells

van de Wetering, M., Sancho, E., Verweij, C., de Lau, W., Oving, I., Hurlstone, A., van der Horn, K., Batlle, E., Coudreuse, D., Haramis, A.-P., et al. (2002) · Cell · doi:10.1016/s0092-8674(02)01014-0 · Cited by 2,030 · see citing works

MECHANISMS OF WNT SIGNALING IN DEVELOPMENT

Wodarz, A., & Nusse, R. (1998) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cellbio.14.1.59 · Cited by 2,017 · see citing works

Many tumors induced by the mouse mammary tumor virus contain a provirus integrated in the same region of the host genome

Nusse, R., & VARMUS, H. E. (1982) · Cell · doi:10.1016/0092-8674(82)90409-3 · Cited by 1,864 · see citing works

Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4

Kořínek, V., Barker, N., Moerer, P., van Donselaar, E. V., Huls, G., Peters, P., & Clevers, H. (1998) · Nature Genetics · doi:10.1038/1270 · Cited by 1,704 · see citing works

Cyclin D1 is a nuclear protein required for cell cycle progression in G1

Baldin, V, Lukas, J., Marcote, M. J., Pagano, M., & Draetta, G. (1993) · Genes &amp; Development · doi:10.1101/gad.7.5.812 · Cited by 1,614 · see citing works

Linking Colorectal Cancer to Wnt Signaling

Bienz, M., & Clevers, H. C. (2000) · Cell · doi:10.1016/s0092-8674(00)00122-7 · Cited by 1,516 · see citing works

Small molecule–mediated disruption of Wnt-dependent signaling in tissue regeneration and cancer

Chen, B., Dodge, M. E., Tang, W., Lü, J., Ma, Z., Fan, C.-W., Wei, S., Hao, W., Kilgore, J. A., Williams, N. S., et al. (2009) · Nature Chemical Biology · doi:10.1038/nchembio.137 · Cited by 1,385 · see citing works

TSC2 Integrates Wnt and Energy Signals via a Coordinated Phosphorylation by AMPK and GSK3 to Regulate Cell Growth

Inoki, K., Ouyang, H., Zhu, T., Lindvall, C., Wang, Y., Zhang, X., Yang, Q., Bennett, C., Harada, Y., Stankunas, K., et al. (2006) · Cell · doi:10.1016/j.cell.2006.06.055 · Cited by 1,377 · see citing works

Hematopoietic Stem Cell Quiescence Maintained by p21 ^cip1/waf1

Cheng, T., Rodrigues, N., Shen, H., Yang, Y.-G., Dombkowski, D., Sykes, M., & Scadden, D. T. (2000) · Science · doi:10.1126/science.287.5459.1804 · Cited by 1,339 · see citing works

LDL-receptor-related proteins in Wnt signal transduction

Tamai, K., Semënov, M. V., Kato, Y., Spokony, R. F., Liu, C., Katsuyama, Y., Hess, F. J., Saint‐Jeannet, J., & He, X. (2000) · Nature · doi:10.1038/35035117 · Cited by 1,334 · see citing works

Conservation of the Chk1 Checkpoint Pathway in Mammals: Linkage of DNA Damage to Cdk Regulation Through Cdc25

Sanchez, Y., Wong, C., Thoma, R. S., Richman, R., Wu, Z., Piwnica-Worms, H., & Elledge, S. J. (1997) · Science · doi:10.1126/science.277.5331.1497 · Cited by 1,320 · see citing works

Epidermal homeostasis: a balancing act of stem cells in the skin

Blanpain, C., & Fuchs, E. (2009) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2636 · Cited by 1,270 · see citing works

G1 cell-cycle control and cancer

Massagué, J. (2004) · Nature · doi:10.1038/nature03094 · Cited by 1,217 · see citing works

c-MYC: more than just a matter of life and death

Pelengaris, S., Khan, M., & Evan, G. I. (2002) · Nature reviews. Cancer · doi:10.1038/nrc904 · Cited by 1,172 · see citing works

Towards an integrated view of Wnt signaling in development

van Amerongen, R., & Nusse, R. (2009) · Development · doi:10.1242/dev.033910 · Cited by 1,168 · see citing works

WNT Signals Are Required for the Initiation of Hair Follicle Development

Andl, T., Reddy, S. T., Gaddapara, T., & Millar, S. E. (2002) · Developmental Cell · doi:10.1016/s1534-5807(02)00167-3 · Cited by 1,088 · see citing works

Multiple roles for activated LEF/TCF transcription complexes during hair follicle development and differentiation

DasGupta, R., & Fuchs, E. V. (1999) · Development · doi:10.1242/dev.126.20.4557 · Cited by 995 · see citing works

Modulation of the dynamic instability of tubulin assembly by the microtubule-associated protein tau.

Drechsel, D. N., Hyman, A. A., Cobb, M. H., & Kirschner, M. W. (1992) · Molecular Biology of the Cell · doi:10.1091/mbc.3.10.1141 · Cited by 971 · see citing works

The Fbw7 tumor suppressor regulates glycogen synthase kinase 3 phosphorylation-dependent c-Myc protein degradation

Welcker, M., Orian, A., Jin, J., Grim, J. A., Harper, J. W., Eisenman, R. N., & Clurman, B. E. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0402770101 · Cited by 942 · see citing works

Wnt Induces LRP6 Signalosomes and Promotes Dishevelled-Dependent LRP6 Phosphorylation

Bilić, J., Huang, Y., Davidson, G. R., Zimmermann, T., Cruciat, C., Bienz, M., & Niehrs, C. (2007) · Science · doi:10.1126/science.1137065 · Cited by 923 · see citing works

Abnormal tau phosphorylation at Ser396 in Alzheimer's disease recapitulates development and contributes to reduced microtubule binding

Bramblett, G. T., Goedert, M., Jakes, R., Merrick, S. E., Trojanowski, J. Q., & Lee, V. M. Y. (1993) · Neuron · doi:10.1016/0896-6273(93)90057-x · Cited by 903 · see citing works

Inactivation of glycogen synthase kinase-3 <i>β</i> by phosphorylation: new kinase connections in insulin and growth-factor signalling

Sutherland, C., Leighton, I. A., & Cohen, P. (1993) · Biochemical Journal · doi:10.1042/bj2960015 · Cited by 903 · see citing works

Association of human cyclin E with a periodic G1-S phase protein kinase

Dulić, V., Lees, E. M., & Reed, S. I. (1992) · Science · doi:10.1126/science.1329201 · Cited by 882 · see citing works

arrow encodes an LDL-receptor-related protein essential for Wingless signalling

Wehrli, M., Dougan, S. T., Caldwell, K. A., O’Keefe, L. V., Schwartz, S. L., Vaizel-Ohayon, D., Schejter, E. D., Tomlinson, A., & DiNardo, S. (2000) · Nature · doi:10.1038/35035110 · Cited by 871 · see citing works

c-Myc is an important direct target of Notch1 in T-cell acute lymphoblastic leukemia/lymphomaPreprint

Weng, A. P., Millholland, J. M., Yashiro–Ohtani, Y., Arcangeli, M.-L., Lau, A. N., Wai, C., Bianco, C. D., Rodríguez, C. G., Sai, H., Tobias, J. W., et al. (2006) · Genes & Development · doi:10.1101/gad.1450406 · Cited by 863 · see citing works

Deconstructing stem cell self-renewal: genetic insights into cell-cycle regulation

Orford, K. W., & Scadden, D. T. (2008) · Nature Reviews Genetics · doi:10.1038/nrg2269 · Cited by 851 · see citing works

A dual-kinase mechanism for Wnt co-receptor phosphorylation and activation

Zeng, X., Tamai, K., Doble, B. W., Li, S., Huang, H., Habas, R., Okamura, H., Woodgett, J. R., & He, X. (2005) · Nature · doi:10.1038/nature04185 · Cited by 849 · see citing works

A Two-Step Mechanism for Stem Cell Activation during Hair Regeneration

Greco, V., Chen, T., Rendl, M., Schober, M., Pasolli, H. A., Stokes, N., dela Cruz-Racelis, J., & Fuchs, E. (2009) · Cell Stem Cell · doi:10.1016/j.stem.2008.12.009 · Cited by 800 · see citing works

LIF/STAT3 controls ES cell self-renewal and pluripotency by a Myc-dependent mechanism

Cartwright, P., McLean, C. A., Sheppard, A. M., Rivett, D., Jones, K., & Dalton, S. (2005) · Development · doi:10.1242/dev.01670 · Cited by 758 · see citing works

Mining the Wnt pathway for cancer therapeutics

Barker, N., & Clevers, H. C. (2006) · Nature Reviews Drug Discovery · doi:10.1038/nrd2154 · Cited by 746 · see citing works

Glycogen synthase kinase-3 induces Alzheimer's disease-like phosphorylation of tau: Generation of paired helical filament epitopes and neuronal localisation of the kinase

Hanger, D. P., Hughes, K., Woodgett, J. R., Brion, J.-P., & Anderton, B. H. (1992) · Neuroscience Letters · doi:10.1016/0304-3940(92)90774-2 · Cited by 737 · see citing works

MAD2 haplo-insufficiency causes premature anaphase and chromosome instability in mammalian cells

Michel, L. S., Liberal, V., Chatterjee, A., Kirchwegger, R., Pasche, B., Gerald, W. L., Dobles, M., Sorger, P. K., Murty, V. V. V. S., & Benezra, R. (2001) · Nature · doi:10.1038/35053094 · Cited by 725 · see citing works

Mutations in the APC tumour suppressor gene cause chromosomal instability

Fodde, R., Kuipers, J., Rosenberg, C., Smits, R., Kielman, M. F., Gaspar, C., van Es, J. H., Breukel, C., Wiegant, J. C. A. G., Giles, R. H., et al. (2001) · Nature Cell Biology · doi:10.1038/35070129 · Cited by 722 · see citing works

Wnt Signaling Requires Sequestration of Glycogen Synthase Kinase 3 inside Multivesicular Endosomes

Taelman, V. F., Dobrowolski, R., Plouhinec, J.-L., Fuentealba, L. C., Vorwald, P. P., Gumper, I., Sabatini, D. D., & Robertis, E. M. D. (2010) · Cell · doi:10.1016/j.cell.2010.11.034 · Cited by 715 · see citing works

Signalling, cell cycle and pluripotency in embryonic stem cells

Burdon, T., Smith, A. T., & Savatier, P. (2002) · Trends in Cell Biology · doi:10.1016/s0962-8924(02)02352-8 · Cited by 710 · see citing works

Axonal Remodeling and Synaptic Differentiation in the Cerebellum Is Regulated by WNT-7a Signaling

Hall, A. C., Lucas, F. R., & Salinas, P. C. (2000) · Cell · doi:10.1016/s0092-8674(00)80689-3 · Cited by 687 · see citing works

A mitogen gradient of dorsal midline Wnts organizes growth in the CNS

Megason, S. G., & McMahon, A. P. (2002) · Development · doi:10.1242/dev.129.9.2087 · Cited by 681 · see citing works

Essential requirement for Wnt signaling in proliferation of adult small intestine and colon revealed by adenoviral expression of Dickkopf-1

Kuhnert, F., Davis, C. R., Wang, H.-T., Chu, P., Lee, M. A., Yuan, J., Nusse, R., & Kuo, C. J. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2536800100 · Cited by 638 · see citing works

Active cyclin B1–Cdk1 first appears on centrosomes in prophase

Jackman, M. R., Lindon, C., Nigg, E. A., & Pines, J. (2003) · Nature Cell Biology · doi:10.1038/ncb918 · Cited by 614 · see citing works

Myc deletion rescues Apc deficiency in the small intestine

Sansom, O. J., Méniel, V. S., Muncan, V., Phesse, T. J., Wilkins, J. A., Reed, K. R., Vass, J. K., Athineos, D., Clevers, H. C., & Clarke, A. R. (2007) · Nature · doi:10.1038/nature05674 · Cited by 614 · see citing works

A common human skin tumour is caused by activating mutations in β-catenin

Chan, E., Gat, U., McNiff, J. M., & Fuchs, E. (1999) · Nature Genetics · doi:10.1038/7747 · Cited by 612 · see citing works

Nanog and transcriptional networks in embryonic stem cell pluripotency

Pan, G., & Thomson, J. A. (2007) · Cell Research · doi:10.1038/sj.cr.7310125 · Cited by 606 · see citing works

Casein kinase 1 γ couples Wnt receptor activation to cytoplasmic signal transduction

Davidson, G. R., Wu, W., Shen, J., Bilić, J., Fenger, U., Stannek, P., Glinka, A., & Niehrs, C. (2005) · Nature · doi:10.1038/nature04170 · Cited by 581 · see citing works

Genes involved in sister chromatid separation are needed for b-type cyclin proteolysis in budding yeast

Irniger, S., Piatti, S., Michaelis, C., & Nasmyth, K. (1995) · Cell · doi:10.1016/0092-8674(95)90337-2 · Cited by 560 · see citing works

Requirement of Prorenin Receptor and Vacuolar H + -ATPase–Mediated Acidification for Wnt Signaling

Cruciat, C., Ohkawara, B., Acebrón, S. P., Karaulanov, E., Reinhard, C., Ingelfinger, D., Boutros, M., & Niehrs, C. (2010) · Science · doi:10.1126/science.1179802 · Cited by 548 · see citing works

Apc Tumor Suppressor Gene Is the “Zonation-Keeper” of Mouse Liver

Benhamouche, S., Decaens, T., Godard, C., Chambrey, R., Rickman, D. S., Moinard, C., Vasseur-Cognet, M., Kuo, C. J., Kahn, A., Perret, C., et al. (2006) · Developmental Cell · doi:10.1016/j.devcel.2006.03.015 · Cited by 543 · see citing works

Distinct Wnt signaling pathways have opposing roles in appendage regeneration

Stoick-Cooper, C. L., Weidinger, G., Riehle, K. J., Hubbert, C. C., Major, M. B., Fausto, N., & Moon, R. T. (2006) · Development · doi:10.1242/dev.001123 · Cited by 533 · see citing works

Inhibition of glycogen synthase kinase-3 alleviates Tcf3 repression of the pluripotency network and increases embryonic stem cell resistance to differentiation

Wray, J. P., Kalkan, T., Gómez‐López, S., Eckardt, D., Cook, A. S., Kemler, R., & Smith, A. G. (2011) · Nature Cell Biology · doi:10.1038/ncb2267 · Cited by 525 · see citing works

Synthesis of RNA and protein during mitosis in mammalian tissue culture cells

Prescott, D. M., & Bender, M. A. (1962) · Experimental Cell Research · doi:10.1016/0014-4827(62)90176-3 · Cited by 520 · see citing works

Tcf3 is an integral component of the core regulatory circuitry of embryonic stem cellsPreprint

Cole, M. F., Johnstone, S. E., Newman, J. J., Kagey, M. H., & Young, R. A. (2008) · Genes & Development · doi:10.1101/gad.1642408 · Cited by 514 · see citing works

Control of Cyclin Ubiquitination by CDK-Regulated Binding of Hct1 to the Anaphase Promoting Complex

Zachariae, W., Schwab, M., Nasmyth, K., & Seufert, W. (1998) · Science · doi:10.1126/science.282.5394.1721 · Cited by 511 · see citing works

Embryonic stem cells require Wnt proteins to prevent differentiation to epiblast stem cells

ten Berge, D., Kurek, D., Blauwkamp, T. A., Koole, W., Maas, A., Eroğlu, E., Siu, R. K., & Nusse, R. (2011) · Nature Cell Biology · doi:10.1038/ncb2314 · Cited by 462 · see citing works

Self‐renewal of human embryonic stem cells is supported by a shortened G1 cell cycle phase

Becker, K. A., Ghule, P. N., Therrien, J. A., Lian, J. B., Stein, J. L., van Wijnen, A. J., & Stein, G. S. (2006) · Journal of Cellular Physiology · doi:10.1002/jcp.20776 · Cited by 460 · see citing works

Translation of cyclin mRNA is necessary for extracts of activated Xenopus eggs to enter mitosis

Minshull, J., Blow, J. J., & Hunt, T. (1989) · Cell · doi:10.1016/0092-8674(89)90628-4 · Cited by 440 · see citing works

The DIX domain of Dishevelled confers Wnt signaling by dynamic polymerization

Schwarz, T., Fiedler, M., Shibata, N., Butler, P. J. G., Kikuchi, A., Higuchi, Y., & Bienz, M. (2007) · Nature Structural & Molecular Biology · doi:10.1038/nsmb1247 · Cited by 429 · see citing works

Myc represses the p21 (WAF1/CIP1) promoter and interacts with Sp1/Sp3

Gartel, A. L., Ye, X., Goufman, E., Shiyanov, P. A., Hay, N., Najmabadi, F., & Tyner, A. L. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.081074898 · Cited by 416 · see citing works

β-Catenin Is Dispensable for Hematopoiesis and Lymphopoiesis

Cobas, M., Wilson, A., Ernst, B., Mancini, S., Macdonald, H., Kemler, R., & Radtke, F. (2004) · Journal of Experimental Medicine · doi:10.1084/jem.20031615 · Cited by 401 · see citing works

Wnt5aandWnt5bexhibit distinct activities in coordinating chondrocyte proliferation and differentiation

Yang, Y., Topol, L. Z., Lee, H., & Wu, J. (2003) · Development · doi:10.1242/dev.00324 · Cited by 398 · see citing works

Control of mitosis by changes in the subcellular location of cyclin-B1–Cdk1 and Cdc25C

Takizawa, C. G., & Morgan, D. O. (2000) · Current Opinion in Cell Biology · doi:10.1016/s0955-0674(00)00149-6 · Cited by 390 · see citing works

Pluripotent cell division cycles are driven by ectopic Cdk2, cyclin A/E and E2F activities

Stead, E., White, J., Faast, R., Conn, S. J., Goldstone, S. D., Rathjen, J., Dhingra, U., Rathjen, P. D., Walker, D., & Dalton, S. (2002) · Oncogene · doi:10.1038/sj.onc.1206015 · Cited by 389 · see citing works

Proteolysis of the Hedgehog Signaling Effector Cubitus interruptus Requires Phosphorylation by Glycogen Synthase Kinase 3 and Casein Kinase 1

Price, M. A., & Kalderon, D. (2002) · Cell · doi:10.1016/s0092-8674(02)00664-5 · Cited by 381 · see citing works

Regulation of cyclin E transcription by E2Fs and retinoblastoma protein.

Geng, Y., Eaton, E. N., Picón, M., Roberts, J. M., Lundberg, A. S., Gifford, A. M., Sardet, C., & Weinberg, R. A. (1996) · PubMed · Cited by 378 · see citing works

Mitotic repression of the transcriptional machinery

Gottesfeld, J. M. (1997) · Trends in Biochemical Sciences · doi:10.1016/s0968-0004(97)01045-1 · Cited by 368 · see citing works

Multisite Phosphorylation by Cdk2 and GSK3 Controls Cyclin E Degradation

Welcker, M., Singer, J. D., Loeb, K. R., Grim, J. A., Bloecher, A., Gurian-West, M., Clurman, B. E., & Roberts, J. M. (2003) · Molecular Cell · doi:10.1016/s1097-2765(03)00287-9 · Cited by 364 · see citing works

Apc modulates embryonic stem-cell differentiation by controlling the dosage of β-catenin signaling

Kielman, M. F., Rindapää, M., Gaspar, C., van Poppel, N., Breukel, C., van Leeuwen, S., Taketo, M. M., Roberts, S., Smits, R., & Fodde, R. (2002) · Nature Genetics · doi:10.1038/ng1045 · Cited by 362 · see citing works

Wnt Signaling, Lgr5, and Stem Cells in the Intestine and Skin

Haegebarth, A., & Clevers, H. C. (2009) · American Journal Of Pathology · doi:10.2353/ajpath.2009.080758 · Cited by 360 · see citing works

Ubiquitination by the anaphase-promoting complex drives spindle checkpoint inactivation

Reddy, S., Rapé, M., Marganski, W. A., & Kirschner, M. W. (2007) · Nature · doi:10.1038/nature05734 · Cited by 356 · see citing works

TERT Promotes Epithelial Proliferation through Transcriptional Control of a Myc- and Wnt-Related Developmental Program

Choi, J., Southworth, L. K., Sarin, K. Y., Venteicher, A. S., Ma, W., Chang, W., Cheung, P., Jun, S., Artandi, M. K., Shah, N., et al. (2008) · PLoS Genetics · doi:10.1371/journal.pgen.0040010 · Cited by 336 · see citing works

Canonical Wnt Signaling Regulates Hematopoiesis in a Dosage-Dependent Fashion

Luis, T. C., Naber, B. A. E., Roozen, P. P. C., Brugman, M. H., de Haas, E. F. E., Ghazvini, M., Fibbe, W. E., van Dongen, J. J. M., Fodde, R., & Staal, F. J. T. (2011) · Cell stem cell · doi:10.1016/j.stem.2011.07.017 · Cited by 323 · see citing works

Coordinated Activation of Wnt in Epithelial and Melanocyte Stem Cells Initiates Pigmented Hair Regeneration

Rabbani, P. S., Takeo, M., Chou, W. C., Myung, P. S., Bosenberg, M., Chin, L., Taketo, M. M., & Ito, M. (2011) · Cell · doi:10.1016/j.cell.2011.05.004 · Cited by 322 · see citing works

Wnt/β-catenin/CBP signaling maintains long-term murine embryonic stem cell pluripotency

Miyabayashi, T., Teo, J.-L., Yamamoto, M., McMillan, M., Nguyen, C., & Kahn, M. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0701331104 · Cited by 310 · see citing works

Advances in signaling in vertebrate regeneration as a prelude to regenerative medicinePreprint

Stoick-Cooper, C. L., Moon, R. T., & Weidinger, G. (2007) · Genes & Development · doi:10.1101/gad.1540507 · Cited by 304 · see citing works

Opposing effects of Tcf3 and Tcf1 control Wnt stimulation of embryonic stem cell self-renewal

Yi, F., Pereira, L., Hoffman, J. A., Shy, B. R., Yuen, C. M., Liu, D. R., & Merrill, B. J. (2011) · Nature Cell Biology · doi:10.1038/ncb2283 · Cited by 303 · see citing works

Regulation of eukaryotic initiation factor eIF2B: glycogen synthase kinase‐3 phosphorylates a conserved serine which undergoes dephosphorylation in response to insulin

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WNT/β-catenin pathway up-regulates Stat3 and converges on LIF to prevent differentiation of mouse embryonic stem cells

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Repression of transcription of the p27Kip1 cyclin-dependent kinase inhibitor gene by c-Myc

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Normal Hematopoiesis Is a Balancing Act of Self-Renewal and RegenerationPreprint

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Thermodynamics in cancers: opposing interactions between PPAR gamma and the canonical WNT/beta‐catenin pathway

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Overexpression of KRT17 promotes proliferation and invasion of non-small cell lung cancer and indicates poor prognosis

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Context Matters: NOTCH Signatures and Pathway in Cancer Progression and Metastasis

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The Wnt cries many: Wnt regulation of neurogenesis through tissue patterning, proliferation, and asymmetric cell division

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miR-142-3pbalances proliferation and differentiation of mesenchymal cells during lung development

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Curcumin suppresses proliferation and induces apoptosis of human hepatocellular carcinoma cells via the wnt signaling pathway

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Expression of Ferritin Light Chain (FTL) Is Elevated in Glioblastoma, and FTL Silencing Inhibits Glioblastoma Cell Proliferation via the GADD45/JNK Pathway

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Complexity of the Wnt/β‑catenin pathway: Searching for an activation model

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The role of Wnt signaling in skin fibrosis

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Primary Cilia Integrate Hedgehog and Wnt Signaling during Tooth Development

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Molecular Profiles of Parvalbumin-Immunoreactive Neurons in the Superior Temporal Cortex in Schizophrenia

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The connections of Wnt pathway components with cell cycle and centrosome: side effects or a hidden logic?

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Inactivation of Lrp5 in osteocytes reduces Young's modulus and responsiveness to the mechanical loading

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Thermodynamics in Gliomas: Interactions between the Canonical WNT/Beta-Catenin Pathway and PPAR Gamma

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A Review of the Role of Wnt in Cancer Immunomodulation

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Dual role of quercetin in enhancing the efficacy of cisplatin in chemotherapy and protection against its side effects: a review

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Maternal Wnt/STOP signaling promotes cell division during early Xenopus embryogenesis

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Wnt meets Warburg: another piece in the puzzle?

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Wnt6 Is Essential for Stromal Cell Proliferation During Decidualization in Mice1

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WNT/β-catenin signaling regulates mitochondrial activity to alter the oncogenic potential of melanoma in a PTEN-dependent manner

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Opposite Interplay Between the Canonical WNT/β-Catenin Pathway and PPAR Gamma: A Potential Therapeutic Target in Gliomas

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Hepatocyte organoids and cell transplantation: What the future holds

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Inhibition of nuclear Wnt signalling: challenges of an elusive target for cancer therapy

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Cytoneme-mediated transport of active Wnt5b–Ror2 complexes in zebrafish

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Significance of miRNAs on the thyroid cancer progression and resistance to treatment with special attention to the role of cross-talk between signaling pathways

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Regulation of influenza virus replication by Wnt/β-catenin signaling

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Targeting phospholipase D1 attenuates intestinal tumorigenesis by controlling β-catenin signaling in cancer-initiating cells

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CTNNB1 mutation associated with familial exudative vitreoretinopathy (FEVR) phenotype

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Wnt/Tcf1 pathway restricts embryonic stem cell cycle through activation of the Ink4/Arf locus

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Activation of STING by cGAMP Regulates MDSCs to Suppress Tumor Metastasis via Reversing Epithelial-Mesenchymal Transition

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DAAM1 and DAAM2 are co-required for myocardial maturation and sarcomere assembly

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Wnt/β-catenin signaling enables developmental transitions during valvulogenesis

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Inflammatory responses in primary muscle cell cultures in Atlantic salmon (Salmo salar)

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Vitamin K3 (menadione) suppresses epithelial-mesenchymal-transition and Wnt signaling pathway in human colorectal cancer cells

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The Krüppel-like factor 9 cistrome in mouse hippocampal neurons reveals predominant transcriptional repression via proximal promoter binding

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How cancer cells remodel lipid metabolism: strategies targeting transcription factors

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Lung fibrosis: Post-COVID-19 complications and evidences

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A Human Pleiotropic Multiorgan Condition Caused by Deficient Wnt Secretion

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Wnt Signaling and Its Contribution to Craniofacial Tissue Homeostasis

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The Wnt Target Protein Peter Pan Defines a Novel p53-independent Nucleolar Stress-Response Pathway

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β-catenin contributes to cordycepin-induced MGMT inhibition and reduction of temozolomide resistance in glioma cells by increasing intracellular reactive oxygen species

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Reduce, reuse, recycle – Developmental signals in spinal cord regeneration

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Regulation and mechanism of YAP/TAZ in the mechanical microenvironment of stem cells (Review)

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Emerging roles of Cdk8 in cell cycle control

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CDK8/19 inhibition induces premature G1/S transition and ATR-dependent cell death in prostate cancer cells

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R-spondin2 signaling is required for oocyte-driven intercellular communication and follicular growth

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Introduction of hsa‐miR‐103a and hsa‐miR‐1827 and hsa‐miR‐137 as new regulators of Wnt signaling pathway and their relation to colorectal carcinoma

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Progranulin gene delivery reduces plaque burden and synaptic atrophy in a mouse model of Alzheimer's disease

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Wnt signalling in cell division: from mechanisms to tissue engineering

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Cyclin‐dependent kinases: Masters of the eukaryotic universe

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MeCP2 modulates the canonical Wnt pathway activation by targeting SFRP4 in rheumatoid arthritis fibroblast-like synoviocytes in rats

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Wnt‐mediated protein stabilization ensures proper mitotic microtubule assembly and chromosome segregation

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Emerging links between CDK cell cycle regulators and Wnt signaling

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Wnt Signaling in Mitosis

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Wnt signalling in cell division: from mechanisms to tissue engineering

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WNT Signaling-Cell Cycle: Regulator of Cancer

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Fresh WNT into the regulation of mitosis

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