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Cited by 277

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Combined SHOOT MERISTEMLESS and WUSCHEL trigger ectopic organogenesis in Arabidopsis

Gallois, Jean-Luc, Woodward, Claire, Reddy, G. Venugopala, Sablowski, Robert·2002·Development
DOI 10.1242/dev.129.13.3207
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Abstract

Almost all aerial parts of plants are continuously generated at the shoot apical meristem (SAM). To maintain a steady pool of undifferentiated cells in the SAM while continuously generating new organs, it is necessary to balance the rate of cell division with the rate of entrance into differentiation pathways. In the Arabidopsis meristem, SHOOT MERISTEMLESS (STM) and WUSCHEL (WUS) are necessary to keep cells undifferentiated and dividing. Here, we tested whether ectopic STM and WUS functions are sufficient to revert differentiation and activate cell division in differentiating tissues. Ectopic STM and WUS functions interacted non-additively and activated a subset of meristem functions, including cell division, CLAVATA1 expression and organogenesis, but not correct phyllotaxy or meristem self-maintenance. Our results suggest that WUS produces a non-cell autonomous signal that activates cell division in combination with STM and that combined WUS/STM functions can initiate the progression from stem cells to organ initiation.

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Metadata

Authors
Gallois, J.-L., Woodward, C., Reddy, G. V., & Sablowski, R.
Venue
Development
Publisher
The Company of Biologists
Published
2002-07-01
Volume
129
Issue
13
Pages
3207-3217
ISSN
  • 0950-1991 (ISSN-L)
  • 1477-9129
DOI
10.1242/dev.129.13.3207
OpenAlex
W2124596764
Cited by
277
References
1
FWCI
20.45
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Combined SHOOT MERISTEMLESS and WUSCHEL trigger ectopic organogenesis in Arabidopsis. https://app.cochat.ai/papers/10.1242/dev.129.13.3207
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Gallois, J.-L., Woodward, C., Reddy, G. V., & Sablowski, R. (2002). Combined SHOOT MERISTEMLESS and WUSCHEL trigger ectopic organogenesis in Arabidopsis. Development. https://doi.org/10.1242/dev.129.13.3207

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