The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Microvesicles: mediators of extracellular communication during cancer progression
Open accessAbstract
Microvesicles are generated by the outward budding and fission of membrane vesicles from the cell surface. Recent studies suggest that microvesicle shedding is a highly regulated process that occurs in a spectrum of cell types and, more frequently, in tumor cells. Microvesicles have been widely detected in various biological fluids including peripheral blood, urine and ascitic fluids, and their function and composition depend on the cells from which they originate. By facilitating the horizontal transfer of bioactive molecules such as proteins, RNAs and microRNAs, they are now thought to have vital roles in tumor invasion and metastases, inflammation, coagulation, and stem-cell renewal and expansion. This Commentary summarizes recent literature on the properties and biogenesis of microvesicles and their potential role in cancer progression.
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Cites
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Wysoczynski, M., & Ratajczak, M. Z. (2009) · International Journal of Cancer · doi:10.1002/ijc.24479 · Cited by 216 · cited 3×
“Microvesicles released by lung cancer cells also activate and chemoattract stromal fibroblasts as well as endothelial cells to facilitate tumor cell growth (Wysoczynski and Ratajczak, 2009).”
Background
Cited by
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Tumor microenvironment differences between primary tumor and brain metastases
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Extracellular Vesicles in Liver Pathobiology: Small Particles With Big Impact
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Wang, Y., Yin, K., Tian, J., Xia, X., Ma, J., Tang, X., Xu, H., & Wang, S. (2019) · Advanced Science · doi:10.1002/advs.201901278 · Cited by 211
Proteomic analysis of urinary extracellular vesicles reveal biomarkers for neurologic disease
Wang, S., Kojima, K., Mobley, J. A., & West, A. B. (2019) · EBioMedicine · doi:10.1016/j.ebiom.2019.06.021 · Cited by 145
Elevated concentration of microvesicles isolated from peripheral blood in breast cancer patients
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Metadata
- Authors
- Muralidharan-Chari, V., Clancy, J. W., Sedgwick, A., & D'Souza-Schorey, C.
- Venue
- Journal of Cell Science
- Publisher
- The Company of Biologists
- Published
- 2010-05-15
- Volume
- 123
- Issue
- 10
- Pages
- 1603-1611
- ISSN
- 0021-9533 (ISSN-L)
- 1477-9137
- OpenAlex
- W1969002010
- Cited by
- 950
- References
- 2
- FWCI
- 17.72
- Type
- journal article
- Language
- en
- Open access
- green
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