MyD88: a central player in innate immune signaling

Role of Adaptor TRIF in the MyD88-Independent Toll-Like Receptor Signaling Pathway

Yamamoto, M., Sato, S., Hemmi, H., Hoshino, K., Kaisho, T., Sanjo, H., Takeuchi, O., Sugiyama, M., Okabe, M., Takeda, K., et al. (2003) · Science · doi:10.1126/science.1087262 · Cited by 3,286

CpG Motifs in Bacterial DNA and Their Immune Effects

Krieg, A. Μ. (2002) · Annual Review of Immunology · doi:10.1146/annurev.immunol.20.100301.064842 · Cited by 2,598

Unresponsiveness of MyD88-deficient mice to endotoxin.

Kawai, T., Adachi, O., Ogawa, T., Takeda, K., & Akira, S. (1999) · Immunity · doi:10.1016/s1074-7613(00)80086-2 · Cited by 2,367

Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18-mediated function.

Adachi, O., Kawai, T., Takeda, K., Matsumoto, M., Tsutsui, H., Sakagami, M., Nakanishi, K., & Akira, S. (1998) · Immunity · doi:10.1016/s1074-7613(00)80596-8 · Cited by 2,358

MyD88 is an adaptor protein in the hToll/IL-1 receptor family signaling pathways.

Medzhitov, R., Preston-Hurlburt, P., Kopp, E., Stadlen, A., Chen, C.-Q., Ghosh, S., & Janeway, C. (1998) · Molecules and Cells · doi:10.1016/s1097-2765(00)80136-7 · Cited by 1,783

Oncogenically active MYD88 mutations in human lymphoma

Ngo, V. N., Young, R. M., Schmitz, R., Jhavar, S. G., Xiao, W., Lim, K., Kohlhammer, H., Xu, W., Yang, Y., Zhao, H., et al. (2010) · Nature · doi:10.1038/nature09671 · Cited by 1,560

Toll-like Receptor Signaling

Akira, S. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.r300028200 · Cited by 1,499

Crystal Structure of the TLR1-TLR2 Heterodimer Induced by Binding of a Tri-Acylated Lipopeptide

Jin, M. S., Kim, S. E., Heo, J. Y., Lee, M. E., Kim, H. M., Paik, S., Lee, H., & Lee, J. (2007) · Cell · doi:10.1016/j.cell.2007.09.008 · Cited by 1,388

Toll-like receptors control activation of adaptive immune responses

Schnare, M., Barton, G. M., Czopik, A. K., Takeda, K., Akira, S., & Medzhitov, R. M. (2001) · Nature Immunology · doi:10.1038/ni712 · Cited by 1,364

TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-β

Kagan, J. C., Su, T., Horng, T., Chow, A. Y., Akira, S., & Medzhitov, R. M. (2008) · Nature Immunology · doi:10.1038/ni1569 · Cited by 1,310

Fucoidan alleviated colitis aggravated by fiber deficiency through protecting the gut barrier, suppressing the MAPK/NF-κB pathway, and modulating gut microbiota and metabolites

Zheng, W., Tang, S., Ren, X., Song, S., & Ai, C. (2025) · Frontiers in Nutrition · doi:10.3389/fnut.2024.1462584 · Cited by 15

Immunosuppression by Intestinal Stromal Cells

Pinchuk, I. V., & Powell, D. W. (2018) · Advances in experimental medicine and biology · doi:10.1007/978-3-319-78127-3_7 · Cited by 17

Anti-Inflammatory Effects of Licania macrocarpa Cuatrec Methanol Extract Target Src- and TAK1-Mediated Pathways

Shin, K. K., Park, J. G., Hong, Y. H., Aziz, N., Park, S. H., Kim, S.-G., Kim, E., & Cho, J. Y. (2019) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2019/4873870 · Cited by 15

Dysregulated NADPH Oxidase Promotes Bone Damage in Murine Model of Autoinflammatory Osteomyelitis

Kralova, J. S., Drobek, A., Procházka, J., Špoutil, F., Fabišik, M., Glatzová, D., Borna, Š., Pokorna, J., Skopcova, T., Angelisová, P., et al. (2020) · The Journal of Immunology · doi:10.4049/jimmunol.1900953 · Cited by 16

Distinct Single Cell Gene Expression in Peripheral Blood Monocytes Correlates With Tumor Necrosis Factor Inhibitor Treatment Response Groups Defined by Type I Interferon in Rheumatoid Arthritis

Muskardin, T. W., Fan, W., Jin, Z., Jensen, M. A., Dorschner, J. M., Ghodke‐Puranik, Y., Dicke, B. A., Vsetecka, D. M., Wright, K., Mason, T., et al. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.01384 · Cited by 15

B-Cell-Specific Myd88 L252P Expression Causes a Premalignant Gammopathy Resembling IgM MGUS

Schmidt, K., Sack, U., Graf, R., Winkler, W., Popp, O., Mertins, P., Sommermann, T. G., Kocks, C., & Rajewsky, K. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.602868 · Cited by 15

Toll-Like Receptors, Associated Biochemical Signaling Networks, and S100 Ligands

Gupta, S., Tsoporis, J. N., Jia, S., dos Santos, C. C., Parker, T. G., & Marshall, J. C. (2020) · Shock · doi:10.1097/shk.0000000000001704 · Cited by 16

Bleeding Propensity in Waldenström Macroglobulinemia: Potential Causes and Evaluation

Brysland, S. A., Maqbool, M. G., Talaulikar, D., & Gardiner, E. E. (2022) · Thrombosis and Haemostasis · doi:10.1055/a-1896-7092 · Cited by 15

The anti-inflammatory effect of lutein in broilers is mediated by regulating Toll-like receptor 4/myeloid-differentiation-factor 88 signaling pathway

Lin, Z., Zhang, M., Yang, R., Min, Y., Guo, P., Zhang, J., Wang, C., Jin, L., & Gao, Y.-Y. (2023) · Poultry Science · doi:10.1016/j.psj.2023.102622 · Cited by 15

Beyond knockout: A novel homodimerization-targeting MyD88 inhibitor prevents and cures type 1 diabetes in NOD mice

Zhang, X., Xing, S., Li, M., Zhang, L., Xie, L., He, W., Liu, J., Chang, S., Jiang, F., & Zhou, P. (2016) · Metabolism · doi:10.1016/j.metabol.2016.05.005 · Cited by 16

Macrophage-Derived IL-1β Regulates Emergency Myelopoiesis via the NF-κB and C/ebpβ in Zebrafish

Wei, Z., Li, C., Zhang, Y., Lin, C., Zhang, Y., Shu, L., Luo, L., Zhuo, J., & Li, L. (2020) · The Journal of Immunology · doi:10.4049/jimmunol.2000473 · Cited by 16

Macrophage polarization in disease therapy: insights from astragaloside IV and cycloastragenol

Xiong, B.-B., Zhuo, Y.-M., Wang, H., Zheng, Q.-L., Tang, F. R., Huang, Q., & Yao, J. Q. (2025) · Frontiers in Pharmacology · doi:10.3389/fphar.2025.1598022 · Cited by 15

Decoding inflammatory signaling networks: From molecular mechanisms to therapeutic targets

Satapathy, T., Patel, N. T., Sahu, P., & Satapathy, A. (2025) · Advances in Biomarker Sciences and Technology · doi:10.1016/j.abst.2025.07.002 · Cited by 14

CIRC_0003907 MODULATES SEPSIS-INDUCED MYOCARDIAL INJURY VIA ENHANCING MYD88/NLRP3/NF-ΚB AXIS BY SPONGING MIR-944

Lv, W., Liu, H., Wang, X., & Hao, R. (2023) · Shock · doi:10.1097/shk.0000000000002271 · Cited by 14

The role of immune system in atherosclerosis: Molecular mechanisms, controversies, and future possibilities

Zhang, T., Pang, C., Xu, M., Zhao, Q., Hu, Z., Jiang, X., & Guo, M. (2024) · Human Immunology · doi:10.1016/j.humimm.2024.110765 · Cited by 14

A model of alcoholic liver disease based on different hepatotoxics leading to liver cancer

Alarcón‐Sánchez, B. R., Idelfonso-García, O. G., Guerrero‐Escalera, D., Piña‐Vázquez, C., de Anda‐Jáuregui, G., Pérez-Hernández, J. L., de la Garza, M., García‐Sierra, F., Sánchez-Pérez, Y., Baltiérrez‐Hoyos, R., et al. (2024) · Biochemical Pharmacology · doi:10.1016/j.bcp.2024.116209 · Cited by 14

The immune interactions of gut glycans and microbiota in health and disease

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The cGAS-STING axis: a comprehensive review from immune defense to disease pathogenesis

Sood, A. (2025) · Immunologic Research · doi:10.1007/s12026-025-09648-z · Cited by 14

The categorization and mutual modulation of expanded MyD88s in Crassostrea gigas

Xin, L., Wang, M., Zhang, H., Li, M., Wang, H., Wang, L., & Song, L. (2016) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2016.04.014 · Cited by 14

A recombinant herpes virus expressing influenza hemagglutinin confers protection and induces antibody-dependent cellular cytotoxicity

Kaugars, K. E., Dardick, J. M., de Oliveira, A. P., Weiss, K. A., Lukose, R., Kim, J., Leung, L. W., Saranathan, R., Wolin, S., Akabas, L. H., et al. (2021) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2110714118 · Cited by 14

TLR/MyD88-Mediated Inflammation Induced in Porcine Intestinal Epithelial Cells by Ochratoxin A Affects Intestinal Barrier Function

Yoon, J. W., Shin, S., Park, J., Lee, B. R., & Lee, S. I. (2023) · Toxics · doi:10.3390/toxics11050437 · Cited by 14

Transcriptional and proteomic analysis of the innate immune response to microbial stimuli in a model invertebrate chordate

Liberti, A., Pollastro, C., Pinto, G., Illiano, A., Marino, R., Amoresano, A., Spagnuolo, A., & Sordino, P. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1217077 · Cited by 15

Unveiling Integrated Functional Pathways Leading to Enhanced Respiratory Disease Associated With Inactivated Respiratory Syncytial Viral Vaccine

Russell, M. S., Creskey, M., Muralidharan, A., Li, C., Gao, J., Chen, W., Larocque, L., Lavoie, J. R., Farnsworth, A., Rosu‐Myles, M., et al. (2019) · Frontiers in Immunology · doi:10.3389/fimmu.2019.00597 · Cited by 14

Mycobacterium indicus pranii therapy induces tumor regression in MyD88- and TLR2-dependent manner

Kumar, P., Das, G., & Bhaskar, S. (2019) · BMC Research Notes · doi:10.1186/s13104-019-4679-0 · Cited by 14

Guttiferone K Exerts the Anti-inflammatory Effect on Mycobacterium Tuberculosis- (H37Ra-) Infected Macrophages by Targeting the TLR/IRAK-1 Mediated Akt and NF-κB Pathway

Zhang, Q., Sun, J., Fu, Y., He, W., Li, Y., Tan, H., Xu, H., & Jiang, X. (2020) · Mediators of Inflammation · doi:10.1155/2020/8528901 · Cited by 14

Whole-genome comparative analysis reveals genetic mechanisms of disease resistance and heat tolerance of tropical Bos indicus cattle breeds

Vijayakumar, P., Singaravadivelan, A., Mishra, A., Jagadeesan, K., Bakyaraj, S., Suresh, R., & Sivakumar, T. (2021) · Genome · doi:10.1139/gen-2021-0030 · Cited by 13

miRNA and mRNA Expression Profiles Associated with Lymph Node Metastasis and Prognosis in Penile Carcinoma

Murta, C. B., Furuya, T. K., Carrasco, A. G. M., Uno, M., Sichero, L. C., Villa, L. L., Faraj, S. F., Coelho, R. F., Guglielmetti, G., Cordeiro, M., et al. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23137103 · Cited by 13

Circ_0138960 knockdown alleviates lipopolysaccharide-induced inflammatory response and injury in human dental pulp cells by targeting miR-545-5p/MYD88 axis in pulpitis

Liang, C., Wu, W., He, X., Xue, F., & Feng, D. (2022) · Journal of Dental Sciences · doi:10.1016/j.jds.2022.06.012 · Cited by 13

Exosomes derived from bone marrow mesenchymal stem cells regulate pyroptosis via the miR-143-3p/myeloid differentiation factor 88 axis to ameliorate intestinal ischemia-reperfusion injury

Wan, Z., Zhang, Y., Zhang, Y., Lv, J., Yuan, Y., Guo, W., & Leng, Y. (2023) · Bioengineered · doi:10.1080/21655979.2023.2253414 · Cited by 13

Interferon signaling drives epithelial metabolic reprogramming to promote secondary bacterial infection

Carreño-Flórez, G. P., Kocak, B. R., Hendricks, M. R., Melvin, J. A., Mar, K. B., Kosanovich, J. L., Cumberland, R. L., Delgoffe, G. M., Shiva, S., Empey, K. M., et al. (2023) · PLoS Pathogens · doi:10.1371/journal.ppat.1011719 · Cited by 13

Integrated compact regulators of protein activity enable control of signaling pathways and genome-editing in vivo

Franko, N., Santinha, A. J., Xue, S., Zhao, H., Hamri, G. C., Platt, R. J., Teixeira, A. P., & Fussenegger, M. (2024) · Cell Discovery · doi:10.1038/s41421-023-00632-1 · Cited by 13

Regulation of immune responses to infection through interaction between stem cell-derived exosomes and toll-like receptors mediated by microRNA cargoes

Moghaddam, M. M., Behzadi, E., Sedighian, H., Goleij, Z., Kachuei, R., Heiat, M., & Fooladi, A. A. I. (2024) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2024.1384420 · Cited by 14

The Improvement and Related Mechanism of Microecologics on the Sports Performance and Post-Exercise Recovery of Athletes: A Narrative Review

Yang, K., Chen, Y., Wang, M., Zhang, Y., Yuan, Y. J., Hou, H., & Mao, Y.-H. (2024) · Nutrients · doi:10.3390/nu16111602 · Cited by 14

Modulation of Neuroinflammation in Poststroke Rehabilitation: The Role of 12/15-Lipoxygenase Inhibition and Baicalein

Tajbakhsh, A., Hosseinpour-Soleimani, F., Abedi, M., Hashempur, M. H., & Negahdaripour, M. (2025) · Stroke · doi:10.1161/strokeaha.124.049048 · Cited by 13

Acute Bacterial Meningitis: Challenges to Better Antibiotic Therapy

Kietzman, C. C., & TUOMANEN, E. I. (2019) · ACS Infectious Diseases · doi:10.1021/acsinfecdis.9b00122 · Cited by 13

Suppressive Effect of Two Cucurbitane-Type Triterpenoids from Momordica charantia on Cutibacterium acnes-Induced Inflammatory Responses in Human THP-1 Monocytic Cell and Mouse Models

Chuang, L., Huang, W.-C., Hou, Y.-C., Chyuan, J., Chang, H., Chang, C., Tsai, T., & Tsai, P. (2021) · Molecules · doi:10.3390/molecules26030579 · Cited by 13

The Astrogenic Balance in the Aging Brain

Andromidas, F., Atashpanjeh, S., Myers, A. J., MacKinnon, B., Shaffer, M. M., & Koob, A. O. (2021) · Current Neuropharmacology · doi:10.2174/1570159x19666210420095118 · Cited by 13

Bacillus subtilis BN strain promotes Th1 response via Toll‐like receptor 2 in polarized mouse M1 macrophage

Tobita, K., & Meguro, R. (2022) · Journal of Food Biochemistry · doi:10.1111/jfbc.14046 · Cited by 13

Curcumin ameliorates oxidized low-density lipoprotein (ox-LDL)-caused damage in human umbilical vein endothelial cells (HUVECs) through the miR-599/MYD88/NF-κB axis

Chen, D., Zhu, C., Ye, S., & Yang, Q. (2022) · Toxicology in Vitro · doi:10.1016/j.tiv.2022.105481 · Cited by 13

Regulation of immune response by S‑1‑propenylcysteine through autophagy‑mediated protein degradation (Review)

Suzuki, J., Miki, S., Ushijima, M., & Kodera, Y. (2019) · Experimental and Therapeutic Medicine · doi:10.3892/etm.2019.8392 · Cited by 13

Overexpression of TOLLIP Protects against Acute Kidney Injury after Paraquat Intoxication through Inhibiting NLRP3 Inflammasome Activation Modulated by Toll‐Like Receptor 2/4 Signaling

Zheng, Q., Zhao, H., Jia, D., Han, X., Liu, Z., & Zhao, M. (2021) · Mediators of Inflammation · doi:10.1155/2021/5571272 · Cited by 13

Adapter proteins regulate insulin resistance and lipid metabolism in obesity

Chen, Z. (2016) · 中国科学通报：英文版 · doi:10.1007/s11434-016-1058-2 · Cited by 13

Evidence-based review of genomic aberrations in diffuse large B cell lymphoma, not otherwise specified (DLBCL, NOS): Report from the cancer genomics consortium lymphoma working group

Yenamandra, A. K., Smith, R. B., Senaratne, T. N., Kang, S.-H. L., Fink, J. M., Corboy, G., Hodge, C. A., Lu, X. Y., Mathew, S., Crocker, S. F., et al. (2022) · Cancer Genetics · doi:10.1016/j.cancergen.2022.07.006 · Cited by 12

Characterization of the Immune-Modulating Properties of Different β-Glucans on Myeloid Dendritic Cells

Rainer, H., Goretzki, A., Lin, Y., Schiller, H. R., Krause, M., Döring, S., Strecker, D., Junker, A., Wolfheimer, S., Toda, M., et al. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25189914 · Cited by 15

Investigation of paeonol in dermatological diseases: an animal study review

Ju, J., Song, T., Shi, J., & Li, J. (2024) · Frontiers in Pharmacology · doi:10.3389/fphar.2024.1450816 · Cited by 12

Discovery of Novel MyD88 Inhibitor A5S to Alleviate Acute Lung Injury with Favorable Drug-like Properties

Chen, P., Zou, Y., Wang, X., Chen, Z., Dong, K., Yang, J., Cui, Y., Gu, J., Wu, X., Li, X., et al. (2024) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.4c02401 · Cited by 12

Role of microRNAs in immunoregulatory functions of epithelial cells

Jafari, N., & Abediankenari, S. (2024) · BMC Immunology · doi:10.1186/s12865-024-00675-3 · Cited by 12

Distinct impacts of aging on the immune responses to extracellular matrix-based versus synthetic biomaterials

Kulkarni, M. M., Popovic, B., Nolfi, A. L., Skillen, C. D., & Brown, B. N. (2025) · Biomaterials · doi:10.1016/j.biomaterials.2025.123204 · Cited by 12

A multiomic analysis of Waldenström macroglobulinemia defines distinct disease subtypes

Gagler, D. C., Ghamlouch, H., Zhang, D., Blaney, P., Tenenbaum, A., Langton, J., Armand, M., Eeckhoutte, A., Joudat, A., Degaud, M., et al. (2025) · Blood · doi:10.1182/blood.2024028164 · Cited by 12

Engineering Supramolecular Organizing Centers for Optogenetic Control of Innate Immune Responses

Tan, P., He, L., & Zhou, Y. (2020) · Advanced Biology · doi:10.1002/adbi.202000147 · Cited by 13

Inflammation plays a causal role in fatigue-like behavior induced by pelvic irradiation in mice

Wolff, B. S., Alshawi, S. A., Feng, L., Juneau, P. L., & Saligan, L. N. (2021) · Brain Behavior & Immunity - Health · doi:10.1016/j.bbih.2021.100264 · Cited by 12

Gossypol ameliorates the IL-1β-induced apoptosis and inflammation in chondrocytes by suppressing the activation of TLR4/MyD88/NF-κB pathway via downregulating CX43

Li, S., Xie, F., Shi, K., Wang, J., Cao, Y. P., & Li, Y. (2021) · Tissue and Cell · doi:10.1016/j.tice.2021.101621 · Cited by 12

Inhibition of LPS-mediated TLR4 activation abrogates gastric adenocarcinoma-associated peritoneal metastasis

Sangwan, V., Al-Marzouki, L., Pal, S., Stavrakos, V., Alzahrani, M. A., Antonatos, D., Nevo, Y., Camilleri‐Broët, S., Rayes, R. F., Bourdeau, F., et al. (2021) · Clinical & Experimental Metastasis · doi:10.1007/s10585-021-10133-8 · Cited by 12

In search of the Aplysia immunome: an in silico study

Kron, N. S. (2022) · BMC Genomics · doi:10.1186/s12864-022-08780-6 · Cited by 12

Early pregnancy affects the expression of toll-like receptor pathway in ovine thymus

Li, N., Wang, L., Cao, N., Zhang, L., Han, X., & Yang, L. (2020) · Reproductive Biology · doi:10.1016/j.repbio.2020.10.003 · Cited by 12

Low-Dose Lipopolysaccharide Protects from Lethal Paramyxovirus Infection in a Macrophage- and TLR4-Dependent Process

Resiliac, J., Rohlfing, M. M., Santoro, J. L., Hussain, S.-R. A., & Grayson, M. H. (2023) · The Journal of Immunology · doi:10.4049/jimmunol.2200604 · Cited by 11

Chlojaponilactone B Attenuates THP-1 Macrophage Pyroptosis by Inhibiting the TLR/MyD88/NF-κB Pathway

Wen, Q., Zhan, B., Jin, L., Peng, Z., Liu, J., Zhu, L., Yang, D., Xu, X., Zhang, L., Li, G., et al. (2024) · Pharmaceuticals · doi:10.3390/ph17030402 · Cited by 11

Both IRAK3 and IRAK1 Activate the MyD88–TRAF6 Pathway in Zebrafish

Weng, P., Lan, M., Zhang, H., Fan, H., Wang, X., Ran, C., Yue, Z., Hu, J., Xu, A., & Huang, S. (2024) · The Journal of Immunology · doi:10.4049/jimmunol.2400054 · Cited by 11

In Vivo Effects of Bay 11-7082 on Fibroid Growth and Gene Expression: A Preclinical Study

Chuang, T., Ton, N., Rysling, S., & Khorram, O. (2024) · Cells · doi:10.3390/cells13131091 · Cited by 11

Interferon Epsilon-Mediated Antiviral Activity Against Human Metapneumovirus and Respiratory Syncytial Virus

Martínez-Espinoza, I., Babawale, P. I., Miletello, H., Cheemarla, N. R., & Guerrero-Plata, A. (2024) · Vaccines · doi:10.3390/vaccines12101198 · Cited by 11

Dietary chlorogenic acid supplementation protects against lipopolysaccharide-induced oxidative stress, inflammation and apoptosis in intestine of amur ide (Leuciscus waleckii)

Wang, Y., Meng, S., Li, D., Liu, S., Li, L., & Wu, L. (2024) · Aquatic Toxicology · doi:10.1016/j.aquatox.2024.107223 · Cited by 11

10 things you wish you knew about inflammatory caspases: A holistic review of their biochemistry, activation, and signalling

Grant, S., & Boucher, D. (2025) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2025.110557 · Cited by 11

Protein overexpression of toll‑like receptor 4 and myeloid differentiation factor 88 in oral squamous cell carcinoma and clinical significance

Li, L., Zhou, Z., Mai, K., Li, P., Wang, Z., Wang, Y., Cao, Y., Ma, X., Zhang, T., & Wang, D. (2021) · Oncology Letters · doi:10.3892/ol.2021.13047 · Cited by 11

Zw10 negatively regulates the MyD88-mediated NF-κB signaling through autophagy in teleost fish

Cao, B., Chen, Y., Cui, J., Sun, Y., & Xu, T. (2022) · Developmental & Comparative Immunology · doi:10.1016/j.dci.2022.104401 · Cited by 11

Tocotrienol in the Management of Nonalcoholic Fatty Liver Disease: A Systematic Review

Chin, K., Ekeuku, S. O., Chew, D. C. H., & Trias, A. (2023) · Nutrients · doi:10.3390/nu15040834 · Cited by 11

Implication of myddosome complex genetic variants in outcome severity of COVID-19 patients

Martínez-Gómez, L. E., Martínez-Armenta, C., Medina-Luna, D., Ordóñez-Sánchez, M. L., Tusié‐Luna, T., Ortega‐Peña, S., Herrera-López, B., Suárez-Ahedo, C., Jiménez-Gutiérrez, G. E., Hidalgo‐Bravo, A., et al. (2023) · Journal of Microbiology Immunology and Infection · doi:10.1016/j.jmii.2023.06.002 · Cited by 11

Role of toll-like receptor in the pathogenesis of oral cancer

Bhardwaj, A., Prasad, D., & Mukherjee, S. (2023) · Cell Biochemistry and Biophysics · doi:10.1007/s12013-023-01191-8 · Cited by 11

MyD88 exacerbates inflammation‐induced bone loss by modulating dynamic equilibrium between Th17/Treg cells and subgingival microbiota dysbiosis

Hsiao, P., Huang, R., Huang, L., Chu, C., Dyke, T. E. V., Mau, L., Cheng, C., Sung, C., Weng, P., Wu, Y., et al. (2024) · Journal of Periodontology · doi:10.1002/jper.23-0561 · Cited by 11

MYD88 L265P mutation promoted malignant B cell resistance against T cell-mediated cytotoxicity via upregulating the IL-10/STAT3 cascade

Qiu, H., Gong, S., Xu, L., Cheng, H., Gao, L., Chen, J., Hu, X., & Yang, J. (2018) · International Immunopharmacology · doi:10.1016/j.intimp.2018.09.024 · Cited by 11

Borrelia burgdorferi basic membrane protein A initiates proinflammatory chemokine storm in THP 1-derived macrophages via the receptors TLR1 and TLR2

Zhao, H., Dai, X., Han, X., Liu, A., Bao, F., Bai, R., Ji, Z., Jian, M., Ding, Z., Abi, M.-E., et al. (2019) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2019.108874 · Cited by 11

Interleukin-1 Receptor-Associated Kinase (IRAK) Signaling in Kaposi Sarcoma-Associated Herpesvirus-Induced Primary Effusion Lymphoma

Seltzer, J., Moorad, R., Schifano, J. M., Landis, J. T., & Dittmer, D. P. (2020) · Journal of Virology · doi:10.1128/jvi.02123-19 · Cited by 11

Upregulated NORAD is implicated in apoptosis, inflammation, and oxidative stress in ulcerative colitis through the nuclear factor-κappaB signaling

Lei, N., Kong, P., Chen, S., Wang, Q., Tang, X., & Liu, F. (2022) · European Journal of Gastroenterology & Hepatology · doi:10.1097/meg.0000000000002370 · Cited by 11

Osteopontin in Alzheimer's disease: A double-edged sword in neurodegeneration and neuroprotection-A systematic review

Azizan, Z., Bazrgar, M., Bazgir, N., Moini, S. H., Ghaseminejad‐Kermani, S., Safa, K., Eshaghian‐dorcheh, A., & Harirchian, M. H. (2025) · CNS Neuroscience & Therapeutics · doi:10.1111/cns.70269 · Cited by 10

Innate immune modulation in transplantation: mechanisms, challenges, and opportunities

Praska, C. E., Tamburrini, R., & Danobeitia, J. S. (2023) · Frontiers in Transplantation · doi:10.3389/frtra.2023.1277669 · Cited by 10

Immunomodulatory effects of a probiotic combination treatment to improve the survival of Pacific oyster (Crassostrea gigas) larvae against infection by Vibrio coralliilyticus

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MyD88: an adapter that recruits IRAK to the IL-1 receptor complex.

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