MyD88: a central player in innate immune signaling

Role of Adaptor TRIF in the MyD88-Independent Toll-Like Receptor Signaling Pathway

Yamamoto, M., Sato, S., Hemmi, H., Hoshino, K., Kaisho, T., Sanjo, H., Takeuchi, O., Sugiyama, M., Okabe, M., Takeda, K., et al. (2003) · Science · doi:10.1126/science.1087262 · Cited by 3,286

CpG Motifs in Bacterial DNA and Their Immune Effects

Krieg, A. Μ. (2002) · Annual Review of Immunology · doi:10.1146/annurev.immunol.20.100301.064842 · Cited by 2,598

Unresponsiveness of MyD88-deficient mice to endotoxin.

Kawai, T., Adachi, O., Ogawa, T., Takeda, K., & Akira, S. (1999) · Immunity · doi:10.1016/s1074-7613(00)80086-2 · Cited by 2,367

Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18-mediated function.

Adachi, O., Kawai, T., Takeda, K., Matsumoto, M., Tsutsui, H., Sakagami, M., Nakanishi, K., & Akira, S. (1998) · Immunity · doi:10.1016/s1074-7613(00)80596-8 · Cited by 2,358

MyD88 is an adaptor protein in the hToll/IL-1 receptor family signaling pathways.

Medzhitov, R., Preston-Hurlburt, P., Kopp, E., Stadlen, A., Chen, C.-Q., Ghosh, S., & Janeway, C. (1998) · Molecules and Cells · doi:10.1016/s1097-2765(00)80136-7 · Cited by 1,783

Oncogenically active MYD88 mutations in human lymphoma

Ngo, V. N., Young, R. M., Schmitz, R., Jhavar, S. G., Xiao, W., Lim, K., Kohlhammer, H., Xu, W., Yang, Y., Zhao, H., et al. (2010) · Nature · doi:10.1038/nature09671 · Cited by 1,560

Toll-like Receptor Signaling

Akira, S. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.r300028200 · Cited by 1,499

Crystal Structure of the TLR1-TLR2 Heterodimer Induced by Binding of a Tri-Acylated Lipopeptide

Jin, M. S., Kim, S. E., Heo, J. Y., Lee, M. E., Kim, H. M., Paik, S., Lee, H., & Lee, J. (2007) · Cell · doi:10.1016/j.cell.2007.09.008 · Cited by 1,391

Toll-like receptors control activation of adaptive immune responses

Schnare, M., Barton, G. M., Czopik, A. K., Takeda, K., Akira, S., & Medzhitov, R. M. (2001) · Nature Immunology · doi:10.1038/ni712 · Cited by 1,364

TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-β

Kagan, J. C., Su, T., Horng, T., Chow, A. Y., Akira, S., & Medzhitov, R. M. (2008) · Nature Immunology · doi:10.1038/ni1569 · Cited by 1,310

Yersinia pestis Exploits Early Activation of MyD88 for Growth in the Lungs during Pneumonic Plague

Olson, R. M., Dhariwala, M. O., Mitchell, W. J., & Anderson, D. M. (2019) · Infection and Immunity · doi:10.1128/iai.00757-18 · Cited by 9

Nitric oxide inhibits interleukin‐1‐mediated protection against Escherichia coli K1‐induced sepsis and meningitis in a neonatal murine model

Chambers, C. A., Lacey, C. A., Brown, D., & Skyberg, J. A. (2021) · Immunology and Cell Biology · doi:10.1111/imcb.12445 · Cited by 9

Increased MYD88 blood transcript in a mouse model of Alzheimer’s disease

Cucoș, C. A., Dobre, M., Dragnea, E. M., Manda, G., & Milanesi, E. (2022) · BMC Neuroscience · doi:10.1186/s12868-022-00699-8 · Cited by 9

Dendritic cell-based immunotherapy for head and neck squamous cell carcinoma: advances and challenges

Chen, W., Li, Z., Tang, J., & Liu, S. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1573635 · Cited by 8

Toll-like receptor-mediated immune imbalance in asthma: controversies, breakthroughs, and future directions

Xu, X., Yu, R., Yang, Z., Li, C., Xiong, H., & Li, C. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1605185 · Cited by 8

The effect of miR-1338 on the immunomodulatory activity of ophiopogon polysaccharide liposome

Duan, X., Pan, X., Cui, J., Ke, L., Liu, J., Song, X., Ma, W., Zhang, W., Liu, Y., & Fan, Y. (2021) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2021.11.019 · Cited by 8

Blood brain barrier permeability and immune function of brain in rainbow trout responding to IHNV infection

Sun, R., Chen, K.-W., Wang, Q., Huang, Z.-Y., Wang, B., Shi, Z.-C., & Ji, W. (2022) · Developmental & Comparative Immunology · doi:10.1016/j.dci.2022.104482 · Cited by 9

Serine-/Cysteine-Based sp2-Iminoglycolipids as Novel TLR4 Agonists: Evaluation of Their Adjuvancy and Immunotherapeutic Properties in a Murine Model of Asthma

González‐Cuesta, M., Lai, A. C., Chi, P., Hsu, I., Liu, N.-T., Wu, K.-C., Fernández, J. M. G., Chang, Y., & Mellet, C. O. (2023) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.2c01948 · Cited by 8

The regulation effect of Atractylodis macrocephalae polysaccharides on the growth performance, antioxidant capacity and immune function in Litopenaeus vannamei

Cui, Y., Zhang, X., Jiao, L., Tao, X., Li, M., Lu, J., Jin, M., Zhang, L., & Zhou, Q. (2023) · Aquaculture Reports · doi:10.1016/j.aqrep.2023.101641 · Cited by 8

Stress-Protective Role of Dietary α-Tocopherol Supplementation in Longfin Yellowtail (Seriola rivoliana) Juveniles

Asencio-Alcudia, G. G., Sepúlveda-Quiroz, C. A., Pérez‐Urbiola, J. C., Rodríguez-Jaramillo, M. D. C., Teles, A., Salas‐Leiva, J. S., Martínez‐García, R., Jiménez‐Martínez, L. D., Galavíz, M. A., Tovar‐Ramírez, D., et al. (2023) · Fishes · doi:10.3390/fishes8100526 · Cited by 8

Non-coding RNAs: Emerging biomarkers and therapeutic targets in ulcerative colitis

Kazmi, I. A., Altamimi, A. S. A., Afzal, M., Majami, A. A., Al-Abbasi, F. A., Almalki, W. H., Alzera, S. I., Kukreti, N., Fuloria, N. K., Fuloria, S., et al. (2023) · Pathology - Research and Practice · doi:10.1016/j.prp.2023.155037 · Cited by 8

Targeting the Innate Immune Kinase IRAK1 in Radioresistant Cancer: Double-Edged Sword or One-Two Punch?

Liu, P. H., & Sidi, S. (2019) · Frontiers in Oncology · doi:10.3389/fonc.2019.01174 · Cited by 8

Lys694Arg polymorphism leads to blunted responses to LPS by interfering TLR4 with recruitment of MyD88

Yang, Y., Hu, Y., Zhou, Y., Liang, T., Tang, H., Ju, H., Shi, Q., & Fang, H. (2020) · Innate Immunity · doi:10.1177/1753425920927479 · Cited by 8

Does oxidatively damaged DNA drive amyloid-β generation in Alzheimer’s disease? A hypothesis

Sanders, O. D., Rajagopal, L., & Rajagopal, J. A. (2021) · Journal of Neurogenetics · doi:10.1080/01677063.2021.1954641 · Cited by 8

Surgical Strikes on Host Defenses: Role of the Viral Protease Activity in Innate Immune Antagonism

Chin, C. V., & Saeed, M. (2022) · Pathogens · doi:10.3390/pathogens11050522 · Cited by 8

Deletion of MyD88 in astrocytes prevents β‐amyloid‐induced neuropathology in mice

Huat, T. J., Onraet, T., Camats‐Perna, J., Newcombe, E. A., Ngo, K. C., Sue, A. N., Mirzaei, M., LaFerla, F. M., & Medeiros, R. (2022) · Glia · doi:10.1002/glia.24285 · Cited by 8

Myeloid differentiation factor 88 expression in eyelid specimens of rosacea

Wladis, E. J., Arunachalam, T., Lajoie, J., Lau, K. W., & Adam, A. P. (2021) · Orbit · doi:10.1080/01676830.2021.1905668 · Cited by 8

Divalent Metal Transporter 1 Knock-Down Modulates IL-1β Mediated Pancreatic Beta-Cell Pro-Apoptotic Signaling Pathways through the Autophagic Machinery

Kang, T., Huang, H., Mandrup-Poulsen, T. R., & Larsen, M. R. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22158013 · Cited by 8

Stress-associated β -glucan administration stimulates the TLR – MYD88 – NFKB1 signaling pathway in Nile tilapia (Oreochromis niloticus)

Beneti, S. A. D. A., dos Reis, I. C., Fierro-Castro, C., Moromizato, B. S., Polycarpo, G. D. V., Miasaki, C. T., & Biller, J. D. (2023) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2023.109089 · Cited by 7

The inflammatory response to birth requires MyD88 and is driven by both mother and offspring

Gray, J. M., Major, K., Castillo‐Ruiz, A., Shipley, M., Gangappa, S., & Forger, N. G. (2023) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2023.11.011 · Cited by 7

The molecular mechanism of gspD gene in regulating the biological characteristics, pathogenicity and virulence gene expression of Photobacterium damselae subsp. damselae

Liu, H., Yu, Y., Wang, C., Wang, Y., Wu, R., Zhang, Z., Liu, D., Liao, M., Rong, X., Li, B., et al. (2025) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2025.141559 · Cited by 7

Thiamine Deficiency and Neuroinflammation Are Important Contributors to Alcohol Use Disorder

Kalapatapu, N., Skinner, S. G., D'Addezio, E., Ponna, S., Cadenas, E., & Davies, D. L. (2025) · Pathophysiology · doi:10.3390/pathophysiology32030034 · Cited by 7

Genomic landscape of IgM-MGUS and patients with stable or progressive asymptomatic Waldenström macroglobulinemia

Bagratuni, T., Theologi, O., Vlachos, C., Kollias, I., Maclachlan, K. H., Aktypi, F. D., Mavrianou‐Koutsoukou, N., Liacos, C., Taouxi, K., Papadimou, A., et al. (2025) · Blood · doi:10.1182/blood.2025030177 · Cited by 7

SARS-CoV-2 mediated dysregulation in cell signaling events drives the severity of COVID-19

Aktar, S., & Amin, S. (2022) · Virus Research · doi:10.1016/j.virusres.2022.198962 · Cited by 7

Immune cells and their related genes provide a new perspective on the common pathogenesis of ankylosing spondylitis and inflammatory bowel diseases

Ding, Y., Yang, Y., & Xue, L. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1137523 · Cited by 7

Thalidomide Alleviates Apoptosis, Oxidative Damage and Inflammation Induced by Pemphigus Vulgaris IgG in HaCat Cells and Neonatal Mice Through MyD88

Luan, C., Lu, Z., Chen, J., Chen, M., Zhao, R., & Li, X. (2023) · Drug Design Development and Therapy · doi:10.2147/dddt.s407242 · Cited by 7

Influence of metallic particles and TNF on the transcriptional regulation of NLRP3 inflammasome-associated genes in human osteoblasts

Sellin, M., Hansmann, D., Bader, R., & Jonitz‐Heincke, A. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1397432 · Cited by 7

Inflammasome‐related gene signatures as prognostic biomarkers in osteosarcoma

Zhang, N., Han, Y., Cao, H., & Wang, Q. (2024) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.18286 · Cited by 7

Targeting Myeloid Differentiation Primary Response Protein 88 (MyD88) and Galectin-3 to Develop Broad-Spectrum Host-Mediated Therapeutics against SARS-CoV-2

Saikh, K. U., Anam, K., Sultana, H., Ahmed, R., Kumar, S., Srinivasan, S., & Ahmed, H. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25158421 · Cited by 7

Biologically active franchetine-type diterpenoid alkaloids: Isolation, synthesis, anti-inflammatory, agalgesic activities, and molecular docking

Xiao, Y., Chang, Y., Liu, Y., Li, T., Qu, W.-R., Cheng, Y., Chen, L., Huang, S., & Zhou, X.-L. (2024) · Bioorganic Chemistry · doi:10.1016/j.bioorg.2024.107834 · Cited by 7

TNFα prevents FGF4-mediated rescue of astrocyte dysfunction and reactivity in human ALS models

Velásquez, E., Savchenko, E., Marmolejo-Martínez-Artesero, S., Challuau, D., Aebi, A., Pomeshchik, Y., Lamas, N. J., Vihinen, M., Rezeli, M., Schneider, B. L., et al. (2024) · Neurobiology of Disease · doi:10.1016/j.nbd.2024.106687 · Cited by 7

Novel Inhibitory Actions of Neuroactive Steroid [3α,5α]-3-Hydroxypregnan-20-One on Toll-like Receptor 4-Dependent Neuroimmune Signaling

Lopez, A. G., Chirasani, V. R., Balan, I. S., O’Buckley, T. K., Adelman, M. R., & Morrow, A. L. (2024) · Biomolecules · doi:10.3390/biom14111441 · Cited by 7

Rational design and therapeutic potential of MyD88 inhibitory peptide in psoriasis

Farooq, M., Ahmad, S. B., Han, J., Patra, M. C., Khan, A. W., Choi, H., Seo, H., Choi, H., Kim, M. S., Kim, W., et al. (2025) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2024.117801 · Cited by 7

Investigating the inflammatory cascade effect of basophil activation in children with allergic rhinitis or asthma, via the IgE-FcεRI-NF-κB signaling pathway

Qiao, Y., & Chen, J. (2021) · Advances in Clinical and Experimental Medicine · doi:10.17219/acem/135756 · Cited by 7

Inhibitory effect of main phenolic acid components of Jacobaea cannabifolia (Less.) on inflammation caused by PM2.5

Xu, B., Wang, Y., Jiang, L., Liu, Z., Liu, D.-R., Zhao, H., Li, S., & Wang, X. (2023) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.1096137 · Cited by 7

A hot water extract of Aralia cordata activates bone marrow‐derived macrophages via a myeloid differentiation protein 88‐dependent pathway and protects mice from bacterial infection

Seo, D., Cho, Y., Gu, S., Kim, D., Park, J., Yi, Y., & Lee, S. (2016) · Microbiology and Immunology · doi:10.1111/1348-0421.12376 · Cited by 8

Severe acute respiratory syndrome (SARS)

Beltz, L. A. (2022) · Elsevier eBooks · doi:10.1016/b978-0-323-98809-4.00004-8 · Cited by 7

Cytokine response after stimulation of culture cells by zinc and probiotic strain

Šefcová, M. A., Levkut, M., Bobíková, K., Karaffová, V., Révajová, V., Maruščáková, I. C., Levkutova, M., Ševčíková, Z., Herich, R., & Levkut, M. (2019) · In Vitro Cellular & Developmental Biology - Animal · doi:10.1007/s11626-019-00401-z · Cited by 7

Sticholysins, pore-forming proteins from a marine anemone can induce maturation of dendritic cells through a TLR4 dependent-pathway

Laborde, R. J., Ishimura, M. E., Abreu-Butin, L., Nogueira, C. V., Grubaugh, D., Cruz‐Leal, Y., Lorenzo, M. D. C. L., Fernández, A., Mesa, C., Pazos, F., et al. (2021) · Molecular Immunology · doi:10.1016/j.molimm.2020.12.032 · Cited by 7

Teleost-specific TLR25/MyD88 signaling promotes K63-linked ubiquitination of IRF1 to induce IFNa gene expression

Li, Y., Yi, S., Tang, W., Shi, L., Yan, H., Ning, L., Pu, J., Shiyi, K., Zhang, L., Chen, X., et al. (2025) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2025.110672 · Cited by 6

A Simplified Herbal Formula Improves Cardiac Function and Reduces Inflammation in Mice Through the TLR-Mediated NF-κB Signaling Pathway

Dong, X., Han, X., Zhang, X., Li, S., Li, Z., Kang, J., Jiang, J., Ni, S.-H., Lu, L., He, Z., et al. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.865614 · Cited by 6

Cytokine Dynamics in Autism: Analysis of BMAC Therapy Outcomes

Maric, D. M., Vojvodić, D., Maric, D. L., Velikic, G. S., Radomir, M., Sokolovac, I., Štefik, D., Ivkovic, N., Šušnjević, S., Puletić, M., et al. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms242015080 · Cited by 6

Toll-like Receptor 4 Signaling Mediates Gastritis and Gastric Cancer

Zhang, Z., Liu, J., Wang, Y., Zhang, L., Zhou, T., Huang, Y., & Zhu, T. (2024) · Current Molecular Medicine · doi:10.2174/0115665240276139231206071742 · Cited by 6

Exploration of the Molecular Mechanism by Which Caveolin-1 Regulates Changes in Blood–Brain Barrier Permeability Leading to Eosinophilic Meningoencephalitis

Chen, A., Lai, S., Lu, C., & Chen, K. (2024) · Tropical Medicine and Infectious Disease · doi:10.3390/tropicalmed9060124 · Cited by 6

Teleost-specific TLR23 in Takifugu rubripes recruits MyD88 to trigger ERK pathway and promotes antibacterial defense

Du, Y.-T., Zhang, H., Li, Y., Li, X.-P., Yuan, Z., & Li, M.-F. (2024) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2024.109724 · Cited by 6

MyD88 deficiency in mammary epithelial cells attenuates lipopolysaccharide (LPS)-induced mastitis in mice

Lin, X., Zhao, Z., Cai, Y., He, Y., Wang, J., Liu, N., Qin, Y., & Wu, Y. (2024) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2024.150569 · Cited by 6

Inhibition of the MyD88 signaling pathway could upregulates Ghrelin expression to synergistically regulate hepatic Echinococcus multilocularis-infected progression

Zhu, J., Zhou, T., Chen, G., Wu, Y., Chen, X., Song, Y., Tuohetali, A., Gao, H., Pang, D., Wen, H., et al. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1512180 · Cited by 6

Advancements in the treatment of cerebral ischemia-reperfusion injury: Acupuncture combined with mesenchymal stem cells transplantation

Li, H., Zhang, J., Ma, K., Ji, J., An, C., Jiang, H., Qu, H. Y., Tang, R., Ren, X., Du, Y., et al. (2025) · Medicine · doi:10.1097/md.0000000000041075 · Cited by 6

Fibroblast-specific MyD88-dependent signaling aggravates inflammation and cardiac dysfunction in the MI heart

Umbarkar, P., Tousif, S., Jaiswal, A. K., Bhati, A. S., Cora, A. T., Sethi, R., Zhang, Q., & Lal, H. (2025) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2025.167703 · Cited by 6

Structural Mechanism of Receptor-Triggered MyD88 Oligomeric Assembly in Innate Immune Signaling

Kasai, K., Imamura, K., Uno, M., Nukui, S., Sekiyama, N., Miyata, T., Makino, F., Yamada, R., Takahashi, Y., Kodera, N., et al. (2026) · Nature Communications · doi:10.1038/s41467-026-71836-8 · Cited by 6

Cytomegalovirus infection elicits a conserved chemokine response from human and guinea pig amnion cells

Putri, D. S., Berkebile, Z. W., Mustafa, H. J., Fernández-Alarcón, C., Abrahante, J. E., Schleiss, M. R., & Bierle, C. J. (2020) · Virology · doi:10.1016/j.virol.2020.06.005 · Cited by 6

BTK Inhibitors and Other Targeted Therapies in Waldenström Macroglobulinemia

Chohan, K. L., & Kapoor, P. (2023) · Hemato · doi:10.3390/hemato4020012 · Cited by 6

Evaluating Prophylactic Effect of Bovine Colostrum on Intestinal Barrier Function in Zonulin Transgenic Mice: A Transcriptomic Study

Asbjornsdottir, B., Sigurðsson, S., Miranda-Ribera, A., Fiorentino, M. R., Konno, T., Lan, J., Gudmundsson, L. S., Gottfreðsson, M., Lauth, B., Birgisdóttir, B. E., et al. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms241914730 · Cited by 6

Alleviation of experimental autoimmune encephalomyelitis by transferring low RelB expression tolerogenic dendritic cells

Zheng, C., Liu, L., Liu, C., Chu, F., Lang, Y., Liu, S., Mi, Y., Zhu, J., & Jin, T. (2023) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2023.166934 · Cited by 6

Exploring the immune interactions between Oncomelania hupensis and Schistosoma japonicum, with a cross-comparison of immunological research progress in other intermediate host snails

Li, H., Chen, Y., Zhu, Y., Feng, Y., Qian, Y., Ye, X., Xu, J., Yang, H., Yu, J., Chen, J., et al. (2023) · Parasites & Vectors · doi:10.1186/s13071-023-06011-9 · Cited by 6

Characterization of an African swine fever virus outbreak in India and comparative analysis of immune genes in infected and surviving crossbreed vs. indigenous Doom pigs

Das, P. J., Sonowal, J., Sengar, G. S., Pegu, S. R., Deb, R., Kumar, S., V, Banik, S., Rajkhowa, S., & Gupta, V. K. (2024) · Archives of Virology · doi:10.1007/s00705-024-06062-y · Cited by 6

Recent advances of adapter proteins in the regulation of heart diseases

Li, T., Jia, L., Li, Y., Song, C., & Chen, Z. (2016) · Heart Failure Reviews · doi:10.1007/s10741-016-9582-3 · Cited by 6

An analysis of the expression and function of myeloid differentiation factor 88 in human osteosarcoma

Chen, J., He, J., Yang, Y., & Jiang, J. (2018) · Oncology Letters · doi:10.3892/ol.2018.9297 · Cited by 6

Pore-forming toxins from sea anemones: from protein-membrane interaction to its implications for developing biomedical applications

Álvarez, C., Pazos, F., Soto, C., Laborde, R. J., & Lanio, M. E. (2020) · Advances in biomembranes and lipid self-assembly · doi:10.1016/bs.abl.2020.02.005 · Cited by 6

Immune dysfunction in the cerebellum of mice lacking the autism candidate gene Engrailed 2

Pangrazzi, L., Genovesi, S., Balasco, L., Cerilli, E., Robol, C., Zunino, G., Piazza, S., Provenzano, G., & Bozzi, Y. (2022) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2022.577870 · Cited by 6

Expression of cathelicidin, ERK, MyD88, and TLR-9 in the blood of women in the pre-pregnancy, pregnancy, and their infant cord blood

Madanchi, H., Danaei, N., Safarieh, E., Maleki, M. S. M., Rostamian, M., Taheri, R., & Mirmohammadkhani, M. (2022) · Human Immunology · doi:10.1016/j.humimm.2022.08.014 · Cited by 6

Intramolecular interaction suggests an autosuppression mechanism for the innate immune adaptor protein MyD88

Uno, M., Watanabe‐Nakayama, T., Konno, H., Akagi, K., Tsutsumi, N., Fukao, T., Shirakawa, M., Ohnishi, H., & Tochio, H. (2018) · Chemical Communications · doi:10.1039/c8cc06480f · Cited by 6

Plans within plans: post-transcriptional regulation governs macrophage responses

Smith, M. H., Parker, R., Patrick, K. L., & Courvan, E. M. C. (2025) · Trends in Immunology · doi:10.1016/j.it.2025.06.001 · Cited by 5

Immunological pathways triggered by Porphyromonas gingivalis in periodontitis: New insights into molecular mechanisms

Ferenc, K., Bożek, A., & Gawron, K. (2025) · Molecular Immunology · doi:10.1016/j.molimm.2025.12.001 · Cited by 5

Deletion of MyD88 in T Cells Improves Antitumor Activity in Melanoma

Bayer, A. L., Padilla-Rolon, D., Smolgovsky, S. A., Hinds, P. W., & Alcaide, P. (2024) · American Journal Of Pathology · doi:10.1016/j.ajpath.2024.02.012 · Cited by 5

Myeloid Differentiation Primary Response Protein 88: An Important Therapeutic Target for Chronic Pain

Liang, H., Fu, L., Li, Z., & Liu, Z. (2025) · Journal of Pain Research · doi:10.2147/jpr.s487685 · Cited by 5

Polymorphism in Toll interacting protein (TOLLIP) gene and its association with Visceral Leishmaniasis

Sarmah, P., Bharali, R., Khatonier, R., & Khan, A. (2020) · Gene Reports · doi:10.1016/j.genrep.2020.100705 · Cited by 5

Cobbling Together the Myddosome

Snyder, M., & Snyder, G. A. (2020) · Structure · doi:10.1016/j.str.2020.05.006 · Cited by 5

Is it possible to intervene early cirrhosis by targeting toll-like receptors to rebalance the intestinal microbiome?

Zhang, J., Zao, X., Zhang, J., Guo, Z., Jin, Q., Chen, G., Gan, D., Du, H., & Ye, Y. (2022) · International Immunopharmacology · doi:10.1016/j.intimp.2022.109627 · Cited by 5

Imperatorin inhibits LPS-induced bone marrow-derived macrophages activation by decreased NF-κB p65 phosphorylation

Jiang, Y., Fang, H., Lin, S., Chen, Y., Fu, Y., Tu, Y., Li, Q., & Hui, Z. (2023) · Immunopharmacology and Immunotoxicology · doi:10.1080/08923973.2023.2196603 · Cited by 5

Suppression of MALAT1 promotes human synovial mesenchymal stem cells enhance chondrogenic differentiation and prevent osteoarthritis of the knee in a rat model via regulating miR-212-5p/MyD88 axis

Gao, Z., Guo, C., Xiang, S., Zhang, H., Wang, Y., & Xu, H. (2024) · Cell and Tissue Research · doi:10.1007/s00441-024-03863-0 · Cited by 5

Withaferin A ameliorates ovarian cancer-induced renal damage through the regulation of expression of inflammatory cytokines

Kumar, K. S., Bosch, K. A., Vemuri, V., Kratholm, N., Rane, M. J., & Kakar, S. S. (2024) · Journal of Ovarian Research · doi:10.1186/s13048-024-01519-9 · Cited by 6

Point Mutation Specific Antibodies in B-Cell and T-Cell Lymphomas and Leukemias: Targeting IDH2, KRAS, BRAF and Other Biomarkers RHOA, IRF8, MYD88, ID3, NRAS, SF3B1 and EZH2

Singh, K., Gollapudi, S., Mittal, S., Small, C., Kumar, J., & Ohgami, R. S. (2021) · Diagnostics · doi:10.3390/diagnostics11040600 · Cited by 5

Cephalosporium curvulum lectin causes mycotic keratitis by initiating infection through MyD88 dependent cellular proliferation and apoptosis in human corneal epithelial cells

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Stage-specific coexpression network analysis of Myc in cohorts of renal cancer

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Functional Involvement of TANK‐Binding Kinase 1 in the MyD88‐Dependent NF‐ κ B Pathway Through Syk

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Immunomodulatory Gene-Splicing Dysregulation in Tumorigenesis: Unmasking the Complexity

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Ablation of myd88 alters the immune gene expression and immune cell recruitment during VHSV infection in zebrafish

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Novel immune checkpoint-related gene model to predict prognosis and treatment responsiveness in low-grade gliomas

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Nepetin Attenuates Atopic Dermatitis in HaCaT Cells and BALB/c Mice through MyD88-MKK3/6-Akt Signaling

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Nucleoredoxin Redox Interactions Are Sensitized by Aging and Potentiated by Chronic Alcohol Consumption in the Mouse Liver

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Effects of a blend of mannan and glucan on growth performance, apparent nutrient digestibility, energy status, and whole-blood immune gene expression of beef steers during a 42-d receiving period

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Elucidating the molecular landscape of tendinitis: the role of inflammasome-related genes and immune interactions

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Multi-dimensional characterization of cellular states reveals clinically relevant immunological subtypes and therapeutic vulnerabilities in ovarian cancer

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Manganese mediates antiviral effects by driving an ATM -TBK1 phosphorylation signaling pathway

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Absence of conserved immune signalling pathways and increased pathogen susceptibility associated to photosymbiosis in acoels

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