MyD88: a central player in innate immune signaling

Role of Adaptor TRIF in the MyD88-Independent Toll-Like Receptor Signaling Pathway

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CpG Motifs in Bacterial DNA and Their Immune Effects

Krieg, A. Μ. (2002) · Annual Review of Immunology · doi:10.1146/annurev.immunol.20.100301.064842 · Cited by 2,598

Unresponsiveness of MyD88-deficient mice to endotoxin.

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Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18-mediated function.

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MyD88 is an adaptor protein in the hToll/IL-1 receptor family signaling pathways.

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Oncogenically active MYD88 mutations in human lymphoma

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Toll-like Receptor Signaling

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Crystal Structure of the TLR1-TLR2 Heterodimer Induced by Binding of a Tri-Acylated Lipopeptide

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Toll-like receptors control activation of adaptive immune responses

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TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-β

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Gut Microbiota as a Trigger for Metabolic Inflammation in Obesity and Type 2 Diabetes

Scheithauer, T. P. M., Rampanelli, E., Nieuwdorp, M., Vallance, B. A., Verchere, C. B., van Raalte, D. H., & Herrema, H. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.571731 · Cited by 715

Cross Talk Pathways Between Coagulation and Inflammation

Foley, J. H., & Conway, E. M. (2016) · Circulation Research · doi:10.1161/circresaha.116.306853 · Cited by 595

Health relevance of the modification of low grade inflammation in ageing (inflammageing) and the role of nutrition

Calder, P. C., Bosco, N., Bourdet‐Sicard, R., Capuron, L., Delzenne, N. M., Dore, J. M., Franceschi, C., Lehtinen, M. J., Recker, T., Salvioli, S., et al. (2017) · Ageing Research Reviews · doi:10.1016/j.arr.2017.09.001 · Cited by 524

The emerging mechanisms and functions of microautophagy

Wang, L., Klionsky, D. J., & Shen, H. (2022) · Nature Reviews Molecular Cell Biology · doi:10.1038/s41580-022-00529-z · Cited by 495

NLRP12-PANoptosome activates PANoptosis and pathology in response to heme and PAMPs

Sundaram, B., Nagakannan, P., Mall, R., Wang, Y., Sarkar, R., Kim, H. J., Malireddi, R. K. S., Karki, R., Janke, L. J., Vogel, P., et al. (2023) · Cell · doi:10.1016/j.cell.2023.05.005 · Cited by 443

CAR T Cell Therapy for Solid Tumors: Bright Future or Dark Reality?

Wagner, J., Wickman, E., DeRenzo, C. C., & Gottschalk, S. M. (2020) · Molecular Therapy · doi:10.1016/j.ymthe.2020.09.015 · Cited by 395

Major pathways involved in macrophage polarization in cancer

Kerneur, C., Cano, C. E., & Olive, D. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.1026954 · Cited by 359

The Role of TLRs in Anti-cancer Immunity and Tumor Rejection

Urban‐Wójciuk, Z., Khan, M. M., Oyler, B. L., Fåhræus, R., Marek-Trzonkowska, N. M., Nita‐Lazar, A., Hupp, T. R., & Goodlett, D. R. (2019) · Frontiers in Immunology · doi:10.3389/fimmu.2019.02388 · Cited by 314

Recent clinical trends in Toll‐like receptor targeting therapeutics

Anwar, M. A., Shah, M., Kim, J., & Choi, S. (2018) · Medicinal Research Reviews · doi:10.1002/med.21553 · Cited by 282

Urate‐induced immune programming: Consequences for gouty arthritis and hyperuricemia

Cabău, G., Crișan, T. O., Klück, V., Popp, R. A., & Joosten, L. A. B. (2019) · Immunological Reviews · doi:10.1111/imr.12833 · Cited by 267

Molecular Mechanisms for the Vicious Cycle between Insulin Resistance and the Inflammatory Response in Obesity

Szukiewicz, D. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24129818 · Cited by 216

CAR-T Therapies in Solid Tumors: Opportunities and Challenges

Guzman, G., Reed, M. R., Bielamowicz, K., Koss, B. S., & Rodriguez, A. (2023) · Current Oncology Reports · doi:10.1007/s11912-023-01380-x · Cited by 210

Mettl14 mediates the inflammatory response of macrophages in atherosclerosis through the NF-κB/IL-6 signaling pathway

Yang, Z., Li, Y., Ran, X., Wang, D., Zheng, X., Zhang, M., Yu, B., Sun, Y., & Wu, J. (2022) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-022-04331-0 · Cited by 198

An examination of the LPS-TLR4 immune response through the analysis of molecular structures and protein–protein interactions

Luo, R., Yao, Y., Chen, Z., & Sun, X. (2025) · Cell Communication and Signaling · doi:10.1186/s12964-025-02149-4 · Cited by 207

New Aspects of Lipotoxicity in Nonalcoholic Steatohepatitis

Méndez‐Sánchez, N., Cruz-Ramón, V., Ramírez-Pérez, O., Hwang, J. P., Barranco-Fragoso, B., & Córdova‐Gallardo, J. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19072034 · Cited by 177

Toll-like receptors: potential targets for lupus treatment

Wu, Y., Tang, W., & Zuo, J. (2015) · Acta Pharmacologica Sinica · doi:10.1038/aps.2015.91 · Cited by 174

The Role of Carbohydrates in the Lipopolysaccharide (LPS)/Toll-Like Receptor 4 (TLR4) Signalling

Cochet, F., & Peri, F. (2017) · International Journal of Molecular Sciences · doi:10.3390/ijms18112318 · Cited by 168

Myeloid Differentiation Primary Response Protein 88 (MyD88): The Central Hub of TLR/IL-1R Signaling

Chen, L., Zheng, L., Chen, P., & Liang, G. (2020) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.0c00884 · Cited by 158

Inflammatory Role of TLR-MyD88 Signaling in Multiple Sclerosis

Zheng, C., Chen, J., Chu, F., Zhu, J., & Jin, T. (2020) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2019.00314 · Cited by 150

Toll-like receptor-guided therapeutic intervention of human cancers: molecular and immunological perspectives

Mukherjee, S., Patra, R., Behzadi, P., Masotti, A., Paolini, A., & Sarshar, M. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1244345 · Cited by 158

Toll-like receptors and their therapeutic potential in Parkinson’s disease and α-synucleinopathies

Kouli, A., Horne, C. B., & Williams-Gray, C. H. (2019) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2019.06.042 · Cited by 143

Rhinitis associated with asthma is distinct from rhinitis alone: The ARIA‐MeDALL hypothesis

Bousquet, J. J., Melén, E., Haahtela, T., Koppelman, G. H., Togias, A. G., Valenta, R., Akdiş, C. A., Czarlewski, W., Rothenberg, M. E., Valiulis, A., et al. (2023) · Allergy · doi:10.1111/all.15679 · Cited by 142

NF-κB Signaling in Ovarian Cancer

Harrington, B. S., & Annunziata, C. M. (2019) · Cancers · doi:10.3390/cancers11081182 · Cited by 134

Synthetic biology in the clinic: engineering vaccines, diagnostics, and therapeutics

Tan, X., Letendre, J. H., Collins, J. J., & Wong, W. W. (2021) · Cell · doi:10.1016/j.cell.2021.01.017 · Cited by 134

RIPK3/MLKL-Mediated Neuronal Necroptosis Modulates the M1/M2 Polarization of Microglia/Macrophages in the Ischemic Cortex

Yang, J., Zhao, Y., Zhang, L., Fan, H., Qi, C., Zhang, K., Liu, X., Fei, L., Chen, S., Wang, M., et al. (2018) · Cerebral Cortex · doi:10.1093/cercor/bhy089 · Cited by 129

Aflatoxin B1 Toxicity and Protective Effects of Curcumin: Molecular Mechanisms and Clinical Implications

Dai, C., Tian, E., Hao, Z., Tang, S., Wang, Z., Sharma, G., Jiang, H., & Shen, J. (2022) · Antioxidants · doi:10.3390/antiox11102031 · Cited by 122

Molecular and Cellular Mechanisms Influenced by Postbiotics

Jastrząb, R., Graczyk, D., & Siedlecki, P. S. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms222413475 · Cited by 129

A Comparative Overview of the Intracellular Guardians of Plants and Animals: NLRs in Innate Immunity and Beyond

Duxbury, Z., Wu, C., & Ding, P. (2021) · Annual Review of Plant Biology · doi:10.1146/annurev-arplant-080620-104948 · Cited by 124

Pathogenicity and virulence of Aspergillus fumigatus

Earle, K., Valero, C., Conn, D. P., Vere, G., Cook, P. C., Bromley, M., Bowyer, P., & Gago, S. (2023) · Virulence · doi:10.1080/21505594.2023.2172264 · Cited by 121

The Molecular Mechanisms of Action of Photobiomodulation Against Neurodegenerative Diseases: A Systematic Review

Bathini, M., Raghushaker, C. R., & Mahato, K. K. (2020) · Cellular and Molecular Neurobiology · doi:10.1007/s10571-020-01016-9 · Cited by 113

Ionizable lipid nanoparticles of mRNA vaccines elicit NF-κB and IRF responses through toll-like receptor 4

Zelkoski, A. E., Lu, Z., Sukumar, G., Dalgard, C. L., Said, H., Alameh, M., Mitre, E. E. S., & Malloy, A. M. W. (2025) · npj Vaccines · doi:10.1038/s41541-025-01124-x · Cited by 117

Roles of linear ubiquitinylation, a crucial regulator of NF ‐κB and cell death, in the immune system

Sasaki, K., & Iwaï, K. (2015) · Immunological Reviews · doi:10.1111/imr.12308 · Cited by 115

A Review of Traumatic Brain Injury and the Gut Microbiome: Insights into Novel Mechanisms of Secondary Brain Injury and Promising Targets for Neuroprotection

Zhu, C. S., Grandhi, R., Patterson, T. F., & Nicholson, S. E. (2018) · Brain Sciences · doi:10.3390/brainsci8060113 · Cited by 112

Foreign body response to synthetic polymer biomaterials and the role of adaptive immunity

Kyriakides, T. R., Kim, H.-J., Zheng, C., Harkins, L., Tao, W., & Deschenes, E. (2022) · Biomedical Materials · doi:10.1088/1748-605x/ac5574 · Cited by 106

The role of Interleukin 1 receptor antagonist in mesenchymal stem cell‐based tissue repair and regeneration

Harrell, C. R., Markovic, B. S., Fellabaum, C., Arsenijevic, N., Djonov, V., & Volarevic, V. (2020) · BioFactors · doi:10.1002/biof.1587 · Cited by 106

Zebrafish: an efficient vertebrate model for understanding role of gut microbiota

Xia, H., Chen, H., Cheng, X., Yin, M., Yao, X., Ma, J., Huang, M., Chen, G., & Liu, H. (2022) · Molecular Medicine · doi:10.1186/s10020-022-00579-1 · Cited by 109

Molecular definition of the endogenous Toll-like receptor signalling pathways

Fisch, D., Zhang, T., Sun, H., Ma, W., Tan, Y., Gygi, S. P., Higgins, D. E., & Kagan, J. C. (2024) · Nature · doi:10.1038/s41586-024-07614-7 · Cited by 111

The Role of Cytokines in the Pathogenesis of Schizophrenia

Dawidowski, B., Górniak, A., Podwalski, P., Lebiecka, Z., Misiak, B., & Samochowiec, J. (2021) · Journal of Clinical Medicine · doi:10.3390/jcm10173849 · Cited by 102

The innate immune response to allotransplants: mechanisms and therapeutic potentials

Ochando, J., Ordikhani, F., Boros, P., & Jordan, S. (2019) · Cellular and Molecular Immunology · doi:10.1038/s41423-019-0216-2 · Cited by 108

Local and Systemic Effects of Porphyromonas gingivalis Infection

Chen, W. A., Dou, Y., Fletcher, H. M., & Boskovic, D. S. (2023) · Microorganisms · doi:10.3390/microorganisms11020470 · Cited by 103

A TLR7-nanoparticle adjuvant promotes a broad immune response against heterologous strains of influenza and SARS-CoV-2

Yin, Q., Luo, W., Mallajosyula, V. V. A., Yang, B., Guo, J., Xie, J., Sun, M., Verma, R., Li, C., Constantz, C. M., et al. (2023) · Nature Materials · doi:10.1038/s41563-022-01464-2 · Cited by 100

Anti-Inflammatory and Antioxidant Properties of β-Sitosterol in Copper Sulfate-Induced Inflammation in Zebrafish (Danio rerio)

Zhang, P., Liu, N., Xue, M., Zhang, M., Liu, W., Xu, C., Fan, Y., Meng, Y., Zhang, Q., & Zhou, Y. K. (2023) · Antioxidants · doi:10.3390/antiox12020391 · Cited by 104

Innate Immune Receptors, Key Actors in Cardiovascular Diseases

Jaén, R. I., Val‐Blasco, A., Prieto, P., Fernández, M. G., Smani, T., Lopez-Sendon, J. L., Delgado, C., Boscá, L., & Fernández‐Velasco, M. (2020) · JACC Basic to Translational Science · doi:10.1016/j.jacbts.2020.03.015 · Cited by 101

MyD88: At the heart of inflammatory signaling and cardiovascular disease

Bayer, A. L., & Alcaide, P. (2021) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2021.08.001 · Cited by 100

Innate Immune Signaling and Its Role in Metabolic and Cardiovascular Diseases

Xu, M. M., Liu, P. P., & Li, H. (2018) · Physiological Reviews · doi:10.1152/physrev.00065.2017 · Cited by 100

Effects of Curcumin on Microglial Cells

Ghasemi, F., Bagheri, H., Barreto, G. E., Read, M. I., & Sahebkar, A. (2019) · Neurotoxicity Research · doi:10.1007/s12640-019-00030-0 · Cited by 97

A Role for IFITM Proteins in Restriction of Mycobacterium tuberculosis Infection

Ranjbar, S., Haridas, V., Jasenosky, L. D., Falvo, J. V., & Goldfeld, A. E. (2015) · Cell Reports · doi:10.1016/j.celrep.2015.09.048 · Cited by 93

Innate Immune Stimulation Using 3D Wireframe DNA Origami

Du, R. R., Cedrone, E., Romanov, A. M., Falkovich, R., Dobrovolskaia, M. A., & Bathe, M. (2022) · ACS Nano · doi:10.1021/acsnano.2c06275 · Cited by 94

Innate immune functions of avian intestinal epithelial cells: Response to bacterial stimuli and localization of responding cells in the developing avian digestive tract

Shira, E. B., & Friedman, A. (2018) · PLoS ONE · doi:10.1371/journal.pone.0200393 · Cited by 91

Innate immunity to adenovirus: lessons from mice

Atasheva, S., Yao, J., & Shayakhmetov, D. M. (2019) · FEBS Letters · doi:10.1002/1873-3468.13696 · Cited by 87

MYD88 in the driver’s seat of B-cell lymphomagenesis: from molecular mechanisms to clinical implications

de Groen, R. A. L., Schrader, A. M. R., Kersten, M. J., Pals, S. T., & Vermaat, J. S. P. (2019) · Haematologica · doi:10.3324/haematol.2019.227272 · Cited by 86

Poly- and Perfluoroalkyl Substances Induce Immunotoxicity via the TLR Pathway in Zebrafish: Links to Carbon Chain Length

Tang, L., Qiu, W., Zhang, S., Wang, J., Yang, X., Xu, B., Magnuson, J. T., Xu, E. G., Wu, M., & Zheng, C. (2023) · Environmental Science & Technology · doi:10.1021/acs.est.2c09716 · Cited by 87

Secreted fungal virulence effector triggers allergic inflammation via TLR4

Dang, E. V., Lei, S., Radkov, A. D., Volk, R. F., Zaro, B. W., & Madhani, H. D. (2022) · Nature · doi:10.1038/s41586-022-05005-4 · Cited by 83

Foundational concepts in the biology of bacterial keratitis

Ung, L., & Chodosh, J. (2021) · Experimental Eye Research · doi:10.1016/j.exer.2021.108647 · Cited by 84

Atherosclerosis: A Comprehensive Review of Molecular Factors and Mechanisms

Tasouli-Drakou, V., Ogurek, I., Shaikh, T., Ringor, M., Dicaro, M. V., & Lei, K. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26031364 · Cited by 79

Engineering sonogenetic EchoBack-CAR T cells

Liu, L., He, P., Wang, Y., Ma, F., Li, D., Bai, Z., Qu, Y., Zhu, L., Yoon, C. W., Yu, X., et al. (2025) · Cell · doi:10.1016/j.cell.2025.02.035 · Cited by 79

A review of skin immune processes in acne

Jin, Z., Song, Y., & He, L. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1324930 · Cited by 77

The therapeutic detoxification of chlorogenic acid against acetaminophen-induced liver injury by ameliorating hepatic inflammation

Zheng, Z., Sheng, Y., Lu, B., & Ji, L. (2015) · Chemico-Biological Interactions · doi:10.1016/j.cbi.2015.05.023 · Cited by 77

Neurosteroid allopregnanolone (3α,5α-THP) inhibits inflammatory signals induced by activated MyD88-dependent toll-like receptors

Balan, I. S., Aurelian, L., Schleicher, R. L., Boero, G., O’Buckley, T. K., & Morrow, A. L. (2021) · Translational Psychiatry · doi:10.1038/s41398-021-01266-1 · Cited by 81

The bioengineering application of hyaluronic acid in tissue regeneration and repair

Chang, W., Chen, L., & Chen, K. (2024) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2024.132454 · Cited by 77

The natural product bergenin ameliorates lipopolysaccharide-induced acute lung injury by inhibiting NF-kappaB activition

Yang, S., Yu, Z., Wang, L., Yuan, T., Wang, X., Zhang, X., Wang, J., Lv, Y., & Du, G. (2017) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2017.02.013 · Cited by 75

Intestinal Barrier Function and Immune Homeostasis Are Missing Links in Obesity and Type 2 Diabetes Development

Riedel, S., Pheiffer, C., Johnson, R., Louw, J., & Muller, C. J. F. (2022) · Frontiers in Endocrinology · doi:10.3389/fendo.2021.833544 · Cited by 78

Unraveling the Complexities of Toll-like Receptors: From Molecular Mechanisms to Clinical Applications

Chen, Y.-H., Wu, K., & Wu, H. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25095037 · Cited by 77

Development of 2-amino-4-phenylthiazole analogues to disrupt myeloid differentiation factor 88 and prevent inflammatory responses in acute lung injury

Chen, L., Chen, H., Chen, P., Zhang, W., Wu, C., Sun, C., Luo, W., Zheng, L., Liu, Z., & Liang, G. (2018) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2018.09.068 · Cited by 73

Advances in Chemistry and Bioactivity of Magnoflorine and Magnoflorine-Containing Extracts

Okoń, E., Kukula-Koch, W. A., Jarząb, A., Hałasa, M., Stepulak, A., & Wawruszak, A. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21041330 · Cited by 71

Polystyrene microplastics mediate inflammatory responses in the chicken thymus by Nrf2/NF-κB pathway and trigger autophagy and apoptosis

Li, J., Yin, K., Hou, L., Zhang, Y., Lu, H., Ma, C., & Xing, M. (2023) · Environmental Toxicology and Pharmacology · doi:10.1016/j.etap.2023.104136 · Cited by 71

Genetically engineered oncolytic bacteria as drug delivery systems for targeted cancer theranostics

Chen, Y., Liu, X., Guo, Y., Wang, J., Zhang, D., Yang, M. J., Shi, J., Tan, W., & Zheng, J. H. (2021) · Acta Biomaterialia · doi:10.1016/j.actbio.2021.02.006 · Cited by 69

Circulating interleukin-1β promotes endoplasmic reticulum stress-induced myocytes apoptosis in diabetic cardiomyopathy via interleukin-1 receptor-associated kinase-2

Liu, Z., Zhao, N., Zhu, H., Zhu, S., Pan, S., Xu, J., Zhang, X., Zhang, Y., & Wang, J. (2015) · Cardiovascular Diabetology · doi:10.1186/s12933-015-0288-y · Cited by 69

A Chimeric GM-CSF/IL18 Receptor to Sustain CAR T-cell Function

Lange, S., Sand, L. G. L., Bell, M., Patil, S. L., Langfitt, D., & Gottschalk, S. (2021) · Cancer Discovery · doi:10.1158/2159-8290.cd-20-0896 · Cited by 68

Cross‐talk between pathogen recognizing Toll‐like receptors and immunoglobulin Fc receptors in immunity

van Egmond, M., Vidarsson, G., & Bakema, J. E. (2015) · Immunological Reviews · doi:10.1111/imr.12333 · Cited by 69

Research progress of mechanisms for tight junction damage on blood–brain barrier inflammation

Zhao, B., Yin, Q., Fei, Y., Zhu, J., Qiu, Y.-Y., Fang, W., & Li, Y. (2020) · Archives of Physiology and Biochemistry · doi:10.1080/13813455.2020.1784952 · Cited by 68

Synbindin restrains proinflammatory macrophage activation against microbiota and mucosal inflammation during colitis

Ai, L., Ren, Y., Zhu, M., Lu, S., Qian, Y., Chen, Z., & Xu, A. (2021) · Gut · doi:10.1136/gutjnl-2020-321094 · Cited by 67

Sulfatides are endogenous ligands for the TLR4–MD-2 complex

Su, L., Athamna, M., Wang, Y., Wang, J., Freudenberg, M. A., Yue, T., Wang, J., Moresco, E. M. Y., He, H., Zor, T., et al. (2021) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2105316118 · Cited by 65

Sleep Deprivation Promotes Endothelial Inflammation and Atherogenesis by Reducing Exosomal miR-182-5p

Li, X., Cao, Y., Xu, X., Wang, C., Ni, Q., Lv, X., Yang, C., Zhang, Z., Qi, X., & Song, G. (2023) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.123.319026 · Cited by 65

Canonical and Non-canonical Inflammasome Activation by Outer Membrane Vesicles Derived From Bordetella pertussis

Elizagaray, M. L., Gomes, M. T. R., Guimarães, E. S., Rumbo, M., Hozbor, D. F., Oliveira, S. C., & Moreno, G. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.01879 · Cited by 67

MyD88/CD40 signaling retains CAR T cells in a less differentiated state

Prinzing, B. L., Schreiner, P. A., Bell, M. R., Fan, Y., Krenciute, G., & Gottschalk, S. M. (2020) · JCI Insight · doi:10.1172/jci.insight.136093 · Cited by 64

Live probiotic bacteria administered in a pathomimetic Leaky Gut Chip ameliorate impaired epithelial barrier and mucosal inflammation

Min, S., Than, N., Shin, Y. C., Hu, G., Shin, W., Ambrosini, Y. M., & Kim, H. J. (2022) · Scientific Reports · doi:10.1038/s41598-022-27300-w · Cited by 64

Molecular mechanisms underlying cyclophosphamide-induced cognitive impairment and strategies for neuroprotection in preclinical models

Ibrahim, K. M., Darwish, S. F., Mantawy, E. M., & El‐Demerdash, E. (2023) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-023-04805-0 · Cited by 66

Astroglial activation: Current concepts and future directions

Edison, P. (2024) · Alzheimer s & Dementia · doi:10.1002/alz.13678 · Cited by 67

High-capacity poly (2-oxazoline) formulation of TLR 7/8 agonist extends survival in a chemo-insensitive, metastatic model of lung adenocarcinoma

Vinod, N., Hwang, D., Azam, S. H., Van Swearingen, A. E. D., Wayne, E., Fussell, S. C., Sokolsky-Papkov, M., Pecot, C. V., & Kabanov, A. V. (2020) · Science Advances · doi:10.1126/sciadv.aba5542 · Cited by 63

Alarmin-activated B cells accelerate murine atherosclerosis after myocardial infarction via plasma cell-immunoglobulin-dependent mechanisms

Kyaw, T. S., Loveland, P. M., Kanellakis, P., Cao, A. H., Kallies, A., Huang, A. L., Peter, K., Toh, B., & Bobik, A. (2020) · European Heart Journal · doi:10.1093/eurheartj/ehaa995 · Cited by 63

Tyrosine Kinase SYK Licenses MyD88 Adaptor Protein to Instigate IL-1α-Mediated Inflammatory Disease

Gurung, P., Fan, G., Lukens, J. R., Vogel, P., Tonks, N. K., & Kanneganti, T. (2017) · Immunity · doi:10.1016/j.immuni.2017.03.014 · Cited by 64

Paradox of complex diversity: Challenges in the diagnosis and management of bacterial keratitis

Singh, R. B., Das, S. K., Chodosh, J., Sharma, N., Zegans, M. E., Kowalski, R. P., & Jhanji, V. (2021) · Progress in Retinal and Eye Research · doi:10.1016/j.preteyeres.2021.101028 · Cited by 63

Dual functional roles of the MyD88 signaling in colorectal cancer development

Wang, L., Yu, K., Zhang, X., & Yu, S. (2018) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2018.07.139 · Cited by 61

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