The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Bone Microdamage and Skeletal Fragility in Osteoporotic and Stress Fractures
Abstract
The accumulation of bone microdamage has been proposed as one factor that contributes to increased skeletal fragility with age and that may increase the risk for fracture in older women. This paper reviews the current status and understanding of microdamage physiology and its importance to skeletal fragility. Several questions are addressed: Does microdamage exist in vivo in bone? If it does, does it impair bone quality? Does microdamage accumulate with age, and is the accumulation of damage with age sufficient to cause a fracture? The nature of the damage repair mechanism is reviewed, and it is proposed that osteoporotic fracture may be a consequence of a positive feedback between damage accumulation and the increased remodeling space associated with repair.
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Citations
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Metadata
- Authors
- Burr, D. B., Forwood, M. R., Fyhrie, D. P., Martin, R. B., Schaffler, M. B., & Turner, C. H.
- Venue
- Journal of Bone and Mineral Research
- Publisher
- Oxford University Press (OUP)
- Published
- 1997-01-01
- Volume
- 12
- Issue
- 1
- Pages
- 6-15
- ISSN
- 0884-0431 (ISSN-L)
- 1523-4681
- OpenAlex
- W2068747322
- Cited by
- 686
- References
- 3
- FWCI
- 26.93
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
