Involvement of the Wnt/β-Catenin Signaling Pathway in the Cellular and Molecular Mechanisms of Fibrosis in Endometriosis

Wnt/β-Catenin Signaling in Development and Disease

Clevers, H. (2006) · Cell · doi:10.1016/j.cell.2006.10.018 · Cited by 5,568 · see citing works

Myofibroblasts and mechano-regulation of connective tissue remodelling

Tomasek, J. J., Gabbiani, G., Hinz, B., Chaponnier, C., & Brown, R. A. (2002) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm809 · Cited by 4,290 · see citing works

Endometriosis

Giudice, L. C., & Kao, L. C. (2004) · The Lancet · doi:10.1016/s0140-6736(04)17403-5 · Cited by 3,166 · see citing works

The RIN: an RNA integrity number for assigning integrity values to RNA measurements

Schroeder, A., Mueller, O., Stocker, S., Salowsky, R., Leiber, M., Gassmann, M., Lightfoot, S., Menzel, W., Granzow, M., & Ragg, T. (2006) · BMC Molecular Biology · doi:10.1186/1471-2199-7-3 · Cited by 2,623 · see citing works

TGF-β signaling and the fibrotic response

Leask, A., & Abraham, D. J. (2004) · The FASEB Journal · doi:10.1096/fj.03-1273rev · Cited by 2,319 · see citing works

Wnt signalling and its impact on development and cancer

Klaus, A., & Birchmeier, W. (2008) · Nature Reviews Cancer · doi:10.1038/nrc2389 · Cited by 1,595 · see citing works

Peritoneal endometriosis, ovarian endometriosis, and adenomyotic nodules of the rectovaginal septum are three different entities

Nisolle, M., & Donnez, J. (1997) · Fertility and Sterility · doi:10.1016/s0015-0282(97)00191-x · Cited by 1,279 · see citing works

Induction of Epithelial-Mesenchymal Transition in Alveolar Epithelial Cells by Transforming Growth Factor-β1

Willis, B. C., Liebler, J. M., Luby‐Phelps, K., Nicholson, A. G., Crandall, E. D., du Bois, R. M., & Borok, Z. (2005) · American Journal Of Pathology · doi:10.1016/s0002-9440(10)62351-6 · Cited by 953 · see citing works

Activation of canonical Wnt signalling is required for TGF-β-mediated fibrosis

Akhmetshina, A., Palumbo, K., Dees, C., Bergmann, C., Venalis, P., Zerr, P., Horn, A., Kireva, T., Beyer, C., Zwerina, J., et al. (2012) · Nature Communications · doi:10.1038/ncomms1734 · Cited by 843 · see citing works

Aberrant Wnt/β-Catenin Pathway Activation in Idiopathic Pulmonary Fibrosis

Chilosi, M., Poletti, V., Zamò, A., Lestani, M., Montagna, L., Piccoli, P., Pedron, S., Bertaso, M., Scarpa, A., Murer, B., et al. (2003) · The American Journal of Pathology · doi:10.1016/s0002-9440(10)64282-4 · Cited by 708 · see citing works

Gene expression analysis reveals matrilysin as a key regulator of pulmonary fibrosis in mice and humans

Zuo, F., Kaminski, N., Eugui, E. M., Allard, J. D., Zohar Yakhini, B., Ben‐Dor, A., Lollini, L. O., Morris, D. G., Kim, Y., DeLustro, B., et al. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.092134099 · Cited by 620 · see citing works

Comparison of relative mRNA quantification models and the impact of RNA integrity in quantitative real-time RT-PCR

Fleige, S., Walf-Vorderwülbecke, V., Huch, S., Prgomet, C., Sehm, J., & Pfaffl, M. W. (2006) · Biotechnology Letters · doi:10.1007/s10529-006-9127-2 · Cited by 574 · see citing works

Deciphering the function of canonical Wnt signals in development and disease: conditional loss- and gain-of-function mutations of β-catenin in micePreprint

Grigoryan, T., Wend, P., Klaus‐Bergmann, A., & Birchmeier, W. (2008) · Genes & Development · doi:10.1101/gad.1686208 · Cited by 558 · see citing works

Functional Wnt Signaling Is Increased in Idiopathic Pulmonary Fibrosis

Königshoff, M., Balsara, N., Pfaff, E.-M., Kramer, M., Chrobak, I., Seeger, W., & Eickelberg, O. (2008) · PLoS ONE · doi:10.1371/journal.pone.0002142 · Cited by 507 · see citing works

Deep endometriosis: definition, diagnosis, and treatment

Koninckx, P. R., Ussia, A., Adamyan, L., Wattiez, A., & Donnez, J. (2012) · Fertility and Sterility · doi:10.1016/j.fertnstert.2012.07.1061 · Cited by 494 · see citing works

Inhibition of Wnt/β-catenin/CREB binding protein (CBP) signaling reverses pulmonary fibrosis

Henderson, W. R., Chi, E. Y., Ye, X., Nguyen, C., Tien, Y.-T., Zhou, B., Borok, Z., Knight, D. A., & Kahn, M. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1001520107 · Cited by 464 · see citing works

Relationship between endometriotic foci and nerves in rectovaginal endometriotic nodules

Anaf, V. (2000) · Human Reproduction · doi:10.1093/humrep/15.8.1744 · Cited by 333 · see citing works

Wnt-Dependent β-Catenin Signaling Is Activated after Unilateral Ureteral Obstruction, and Recombinant Secreted Frizzled-Related Protein 4 Alters the Progression of Renal Fibrosis

Surendran, K., Schiavi, S. C., & Hruska, K. A. (2005) · Journal of the American Society of Nephrology · doi:10.1681/asn.2004110949 · Cited by 258 · see citing works

Wnt signaling in stem and cancer stem cells

Wend, P., Holland, J. D., Ziebold, U., & Birchmeier, W. (2010) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2010.09.004 · Cited by 236 · see citing works

Targeting the β-catenin/TCF transcriptional complex in the treatment of multiple myeloma

Sukhdeo, K., Mani, M., Zhang, Y., Dutta, J., Yasui, H., Rooney, M., Carrasco, D. E., Zheng, M., He, H., Tai, Y., et al. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0610299104 · Cited by 219 · see citing works

Epithelial to mesenchymal transition-like and mesenchymal to epithelial transition-like processes might be involved in the pathogenesis of pelvic endometriosis†

Matsuzaki, S., & Darcha, C. (2012) · Human Reproduction · doi:10.1093/humrep/der442 · Cited by 216 · see citing works

Transcriptional Cooperation between the Transforming Growth Factor-β and Wnt Pathways in Mammary and Intestinal Tumorigenesis

Labbé, E., Lock, L. S., Letamendı́a, A., Gorska, A. E., Gryfe, R., Gallinger, S., Moses, H. L., & Attisano, L. (2007) · Cancer Research · doi:10.1158/0008-5472.can-06-2559 · Cited by 170 · see citing works

Role of TGF- s in normal human endometrium and endometriosis

Omwandho, C. O. A., Konrad, L., Halis, G., Oehmke, F., & Tinneberg, H.-R. (2009) · Human Reproduction · doi:10.1093/humrep/dep382 · Cited by 164 · see citing works

Impaired Down-Regulation of E-Cadherin and β-Catenin Protein Expression in Endometrial Epithelial Cells in the Mid-Secretory Endometrium of Infertile Patients with Endometriosis

Matsuzaki, S., Darcha, C., Maleysson, E., Canis, M. J., & Mage, G. (2010) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2009-2713 · Cited by 116 · see citing works

Host-Derived TGFB1 Deficiency Suppresses Lesion Development in a Mouse Model of Endometriosis

Hull, M. L., Johan, M. Z., Hodge, W. L., Robertson, S. A., & Ingman, W. V. (2011) · American Journal Of Pathology · doi:10.1016/j.ajpath.2011.11.013 · Cited by 81 · see citing works

In Vitro Effects of a Small-Molecule Antagonist of the Tcf/ß-Catenin Complex on Endometrial and Endometriotic Cells of Patients with Endometriosis

Matsuzaki, S., & Darcha, C. (2013) · PLoS ONE · doi:10.1371/journal.pone.0061690 · Cited by 72 · see citing works

Fibrogenesis in Peritoneal Endometriosis

Matsuzaki, S., Canis, M. J., Darcha, C., Dechelotte, P., Pouly, J. L., & Bruhat, M. (1999) · Gynecologic and Obstetric Investigation · doi:10.1159/000010094 · Cited by 52 · see citing works

The Potential for Targeting Oncogenic WNT/β -Catenin Signaling in Therapy

Ewan, K., & Dale, T. C. (2008) · Current Drug Targets · doi:10.2174/138945008784911787 · Cited by 30 · see citing works

Proteolytic activation of latent TGF‐β precedes caspase‐3 activation and enhances apoptotic death of lung epithelial cells

Solovyan, V. T., & Keski‐Oja, J. (2006) · Journal of Cellular Physiology · doi:10.1002/jcp.20607 · Cited by 28 · see citing works

Polystyrene microplastics cause granulosa cells apoptosis and fibrosis in ovary through oxidative stress in rats

An, R., Wang, X., Yang, L., Zhang, J., Wang, N., Xu, F., Hou, Y., Zhang, H., & Zhang, L. (2020) · Toxicology · doi:10.1016/j.tox.2020.152665 · Cited by 462 · see citing works

Platelets drive smooth muscle metaplasia and fibrogenesis in endometriosis through epithelial–mesenchymal transition and fibroblast-to-myofibroblast transdifferentiation

Zhang, Q., Duan, J., Liu, X., & Guo, S.-W. (2016) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2016.03.015 · Cited by 211 · see citing works

Corroborating evidence for platelet-induced epithelial-mesenchymal transition and fibroblast-to-myofibroblast transdifferentiation in the development of adenomyosis

Liu, X., Shen, M., Qi, Q., Zhang, H., & Guo, S.-W. (2016) · Human Reproduction · doi:10.1093/humrep/dew018 · Cited by 190 · see citing works

Pharmaceuticals targeting signaling pathways of endometriosis as potential new medical treatment: A review

Hung, S. W., Zhang, R., Tan, Z., Chung, J. P. W., Zhang, T., & Wang, C. C. (2021) · Medicinal Research Reviews · doi:10.1002/med.21802 · Cited by 171 · see citing works

Epithelial-to-mesenchymal transition in the development of endometriosis

Yang, Y., & Yang, W. (2017) · Oncotarget · doi:10.18632/oncotarget.16472 · Cited by 167 · see citing works

Cellular changes consistent with epithelial-mesenchymal transition and fibroblast-to-myofibroblast transdifferentiation in the progression of experimental endometriosis in baboons

Zhang, Q., Duan, J., Olson, M., Fazleabas, A., & Guo, S.-W. (2016) · Reproductive Sciences · doi:10.1177/1933719116641763 · Cited by 149 · see citing works

Endometriosis: Cellular and Molecular Mechanisms Leading to Fibrosis

Garcia, J. M. G., Vannuzzi, V., Donati, C., Bernacchioni, C., Bruni, P., & Petraglia, F. (2022) · Reproductive Sciences · doi:10.1007/s43032-022-01083-x · Cited by 145 · see citing works

The role of fibrosis in endometriosis: a systematic review

Vissers, G., Giacomozzi, M., Verdurmen, W. P. R., Peek, R., & Nap, A. W. (2024) · Human Reproduction Update · doi:10.1093/humupd/dmae023 · Cited by 130 · see citing works

Fibrogenesis resulting from cyclic bleeding: the Holy Grail of the natural history of ectopic endometrium

Guo, S.-W. (2018) · Human Reproduction · doi:10.1093/humrep/dey015 · Cited by 116 · see citing works

Molecular aspects of development and regulation of endometriosis

Aznaurova, Y. B., M.B.Zhumataev, M. B. Z., Roberts, T. K., Aliper, A. M., & Zhavoronkov, A. A. (2014) · Reproductive Biology and Endocrinology · doi:10.1186/1477-7827-12-50 · Cited by 116 · see citing works

Research advances in endometriosis-related signaling pathways: A review

Zhang, M., Xu, T., Tong, D., Li, S., Yu, X., Liu, B., Jiang, L., & Liu, K. (2023) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2023.114909 · Cited by 119 · see citing works

Histological and Immunohistochemical Characterization of the Similarity and Difference Between Ovarian Endometriomas and Deep Infiltrating Endometriosis

Liu, X., Zhang, Q., & Guo, S.-W. (2018) · Reproductive Sciences · doi:10.1177/1933719117718275 · Cited by 110 · see citing works

Exosomal miR-214 from endometrial stromal cells inhibits endometriosis fibrosis

Wu, D., Lu, P., Mi, X., & Miao, J. (2018) · Molecular Human Reproduction · doi:10.1093/molehr/gay019 · Cited by 96 · see citing works

Antifibrotic properties of epigallocatechin-3-gallate in endometriosis

Matsuzaki, S., & Darcha, C. (2014) · Human Reproduction · doi:10.1093/humrep/deu123 · Cited by 95 · see citing works

Dating endometriotic ovarian cysts based on the content of cyst fluid and its potential clinical implications

Guo, S.-W., Ding, D., Shen, M., & Liu, X. (2015) · Reproductive Sciences · doi:10.1177/1933719115570907 · Cited by 86 · see citing works

Enhancer of Zeste homolog 2 (EZH2) induces epithelial-mesenchymal transition in endometriosis

Zhang, Q., Dong, P., Liu, X., Sakuragi, N., & Guo, S. (2017) · Scientific Reports · doi:10.1038/s41598-017-06920-7 · Cited by 89 · see citing works

Co-operation between the AKT and ERK signaling pathways may support growth of deep endometriosis in a fibrotic microenvironment in vitro†

Matsuzaki, S., & Darcha, C. (2015) · Human Reproduction · doi:10.1093/humrep/dev108 · Cited by 88 · see citing works

Genome-wide enrichment analysis between endometriosis and obesity-related traits reveals novel susceptibility loci

Rahmioglu, N., Macgregor, S., Drong, A. W., Hedman, A. K., Harris, H. R., Randall, J. C., Prokopenko, I., The International Endogene Consortium (IEC), T. G. C., Nyholt, D. R., Morris, A. P., et al. (2015) · Human Molecular Genetics · doi:10.1093/hmg/ddu516 · Cited by 85 · see citing works

Neuropeptides Substance P and Calcitonin Gene Related Peptide Accelerate the Development and Fibrogenesis of Endometriosis

Yan, D., Liu, X., & Guo, S.-W. (2019) · Scientific Reports · doi:10.1038/s41598-019-39170-w · Cited by 82 · see citing works

Bioinformatic analysis reveals the importance of epithelial-mesenchymal transition in the development of endometriosis

Chen, M., Zhou, Y., Xu, H. A., Hill, C. N., Ewing, R. M., He, D., Zhang, X., & Wang, Y. (2020) · Scientific Reports · doi:10.1038/s41598-020-65606-9 · Cited by 78 · see citing works

Advanced Role of Hippo Signaling in Endometrial Fibrosis

Zhu, H.-Y., Ge, T., Pan, Y., & Zhang, S. (2017) · Chinese Medical Journal · doi:10.4103/0366-6999.218013 · Cited by 78 · see citing works

Progressive development of endometriosis and its hindrance by anti-platelet treatment in mice with induced endometriosis

Zhang, Q., Liu, X., & Guo, S.-W. (2017) · Reproductive BioMedicine Online · doi:10.1016/j.rbmo.2016.11.006 · Cited by 76 · see citing works

Endometriosis and ovarian cancer: potential benefits and harms of screening and risk-reducing surgery

Guo, S. (2015) · Fertility and Sterility · doi:10.1016/j.fertnstert.2015.08.006 · Cited by 73 · see citing works

Blocking the Wnt/β‑catenin signaling pathway to treat colorectal cancer: Strategies to improve current therapies (Review)

Chen, Y., Chen, M., & Deng, K. (2022) · International Journal of Oncology · doi:10.3892/ijo.2022.5472 · Cited by 69 · see citing works

17 β-Estradiol promotes vascular endothelial growth factor expression via the Wnt/β-catenin pathway during the pathogenesis of endometriosis

Zhang, L., Xiong, W., Xiong, Y., Liu, H., & Liu, Y. (2016) · Molecular Human Reproduction · doi:10.1093/molehr/gaw025 · Cited by 69 · see citing works

P-selectin as a potential therapeutic target for endometriosis

Guo, S., Ding, D., Geng, J.-G., Wang, L., & Liu, X. (2015) · Fertility and Sterility · doi:10.1016/j.fertnstert.2015.01.001 · Cited by 68 · see citing works

EZH2‐mediated repression of Dkk1 promotes hepatic stellate cell activation and hepatic fibrosis

Yang, Y., Chen, X., Li, W., Wu, X., Huang, C., Xie, J., Zhao, Y., Meng, X., & Li, J. (2017) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.13153 · Cited by 62 · see citing works

Cancer driver mutations in endometriosis: Variations on the major theme of fibrogenesis

Guo, S. (2018) · Reproductive Medicine and Biology · doi:10.1002/rmb2.12221 · Cited by 58 · see citing works

Endometriosis and ovarian cancer: links, risks, and challenges faced

Pavone, M. E., & Lyttle, B. (2015) · International Journal of Women s Health · doi:10.2147/ijwh.s66824 · Cited by 59 · see citing works

Molecular Characteristics of the Endometrium in Uterine Adenomyosis and Its Biochemical Microenvironment

Yen, C., Huang, S.-T. J., Lee, C., Wang, H., & Liao, S. (2017) · Reproductive Sciences · doi:10.1177/1933719117691141 · Cited by 57 · see citing works

Resistance to targeted therapy in metastatic colorectal cancer: Current status and new developments

Tang, Y., Li, D., Duan, J.-Y., Sheng, L., & Wang, X. (2023) · World Journal of Gastroenterology · doi:10.3748/wjg.v29.i6.926 · Cited by 58 · see citing works

Malignant Transformation and Associated Biomarkers of Ovarian Endometriosis: A Narrative Review

Михалева, Л. М., Davydov, A. I., Игоревна, П. О., Вячеславовна, М. Е., Nikolenko, V. N., Евгеньевна, Н. М., Klochkov, S. G., Somasundaram, S. G., Kirkland, C. E., & Aliev, G. M. (2020) · Advances in Therapy · doi:10.1007/s12325-020-01363-5 · Cited by 59 · see citing works

The elusive and controversial roles of estrogen and progesterone receptors in human endometriosis.

Shao, R., Cao, S., Wang, X., Feng, Y., & Billig, H. (2014) · Europe PMC (PubMed Central) · Cited by 55 · see citing works

Endometriotic mesenchymal stem cells significantly promote fibrogenesis in ovarian endometrioma through the Wnt/β-catenin pathway by paracrine production of TGF-β1 and Wnt1

Li, J., Dai, Y., Zhu, H., Jiang, Y., & Zhang, S. (2016) · Human Reproduction · doi:10.1093/humrep/dew058 · Cited by 55 · see citing works

MicroRNA‑326 inhibits endometrial fibrosis by regulating TGF‑β1/Smad3 pathway in intrauterine adhesions

Ning, J., Zhang, H., & Yang, H. (2018) · Molecular Medicine Reports · doi:10.3892/mmr.2018.9187 · Cited by 52 · see citing works

NR4A1 is Involved in Fibrogenesis in Ovarian Endometriosis

Zeng, X., Zhang, Y., Gao, Y., Jiang, G., Zeng, F., Shao, Y., Huang, J., Yin, M., & Li, Y. (2018) · Cellular Physiology and Biochemistry · doi:10.1159/000488838 · Cited by 51 · see citing works

Epigenetic Modulation of Collagen 1A1: Therapeutic Implications in Fibrosis and Endometriosis1

Zheng, Y., Khan, Z., Zanfagnin, V., Correa, L. F., Delaney, A. A., & Daftary, G. S. (2016) · Biology of Reproduction · doi:10.1095/biolreprod.115.138115 · Cited by 50 · see citing works

Intracellular Wnt/Beta-Catenin Signaling Underlying 17beta-Estradiol-Induced Matrix Metalloproteinase 9 Expression in Human Endometriosis1

Zhang, L., Xiong, W., Xiong, Y., Liu, H., Li, N., Du, Y., & Liu, Y. (2016) · Biology of Reproduction · doi:10.1095/biolreprod.115.135574 · Cited by 49 · see citing works

Evidence in Support for the Progressive Nature of Ovarian Endometriomas

Ding, D., Wang, X., Chen, Y.-S., Benagiano, G., Liu, X., & Guo, S. (2020) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/clinem/dgaa189 · Cited by 49 · see citing works

Effects of Pazopanib, Sunitinib, and Sorafenib, Anti-VEGF Agents, on the Growth of Experimental Endometriosis in Rats

Yıldız, Ç., Kaçan, T., Akkar, Ö. B., Karakuş, S., Kaçan, S. B., Özer, H., & Çetin, A. (2015) · Reproductive Sciences · doi:10.1177/1933719115584448 · Cited by 47 · see citing works

Effects of matrix stiffness on epithelial to mesenchymal transition-like processes of endometrial epithelial cells: Implications for the pathogenesis of endometriosis

Matsuzaki, S., Darcha, C., Pouly, J. L., & Canis, M. J. (2017) · Scientific Reports · doi:10.1038/srep44616 · Cited by 44 · see citing works

Mechanisms Underlying Adenomyosis-Related Fibrogenesis

Kobayashi, H., Kishi, Y., & Matsubara, S. (2019) · Gynecologic and Obstetric Investigation · doi:10.1159/000502822 · Cited by 44 · see citing works

Mesothelial Cells Participate in Endometriosis Fibrogenesis Through Platelet-Induced Mesothelial-Mesenchymal Transition

Yan, D., Liu, X., Xu, H., & Guo, S. (2020) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/clinem/dgaa550 · Cited by 44 · see citing works

Targeting the Wnt/β-catenin pathway in endometriosis: a potentially effective approach for treatment and prevention

Matsuzaki, S., Botchorishvili, R., Pouly, J. L., & Canis, M. J. (2014) · Molecular and Cellular Therapies · doi:10.1186/s40591-014-0036-9 · Cited by 43 · see citing works

Soft matrices inhibit cell proliferation and inactivate the fibrotic phenotype of deep endometriotic stromal cells in vitro

Matsuzaki, S., Canis, M. J., Pouly, J. L., & Darcha, C. (2016) · Human Reproduction · doi:10.1093/humrep/dev333 · Cited by 43 · see citing works

In vitro and in vivo effects of MK2206 and chloroquine combination therapy on endometriosis: autophagy may be required for regrowth of endometriosis

Matsuzaki, S., Pouly, J. L., & Canis, M. J. (2018) · British Journal of Pharmacology · doi:10.1111/bph.14170 · Cited by 41 · see citing works

IL-37 affects the occurrence and development of endometriosis by regulating the biological behavior of endometrial stromal cells through multiple signaling pathways

Jiang, J., Yu, K., Jiang, Z., & Xue, M. (2018) · Biological Chemistry · doi:10.1515/hsz-2018-0254 · Cited by 40 · see citing works

CD146 defines commitment of cultured annulus fibrosus cells to express a contractile phenotype

Nakai, T., Sakai, D., Nakamura, Y., Nukaga, T., Grad, S., Li, Z., Alini, M., Chan, D. T.-M., Masuda, K., Ando, K., et al. (2016) · Journal of Orthopaedic Research® · doi:10.1002/jor.23326 · Cited by 40 · see citing works

Platelets induce endothelial–mesenchymal transition and subsequent fibrogenesis in endometriosis

Yan, D., Liu, X., Xu, H., & Guo, S. (2020) · Reproductive BioMedicine Online · doi:10.1016/j.rbmo.2020.03.020 · Cited by 39 · see citing works

The Wnt/β-catenin signaling in endometriosis, the expression of total and active forms of β-catenin, total and inactive forms of glycogen synthase kinase-3β, WNT7a and DICKKOPF-1

Pazhohan, A., Amidi, F., Akbari-Asbagh, F., Seyedrezazadeh, E., Farzadi, L., Khodarahmin, M., Mehdinejadiani, S., & Sobhani, A. (2017) · European Journal of Obstetrics & Gynecology and Reproductive Biology · doi:10.1016/j.ejogrb.2017.10.025 · Cited by 38 · see citing works

Secreted frizzled-related protein 2 (SFRP2) expression promotes lesion proliferation via canonical WNT signaling and indicates lesion borders in extraovarian endometriosis

Heinosalo, T., Gabriel, M., Kallio, L., Adhikari, P. R., Huhtinen, K., Laajala, T. D., Kaikkonen, E., Mehmood, A., Suvitie, P. A., Kujari, H. P., et al. (2018) · Human Reproduction · doi:10.1093/humrep/dey026 · Cited by 35 · see citing works

The global burden of polycystic ovary syndrome, endometriosis, uterine fibroids, cervical cancer, uterine cancer, and ovarian cancer from 1990 to 2021

Tang, W., Cai, Q., Huang, K.-J., Xu, W., Li, J., Pan, Y.-R., Xu, J., Zhao, Y.-F., Sheng, T.-H., Li, Z., et al. (2025) · BMC Public Health · doi:10.1186/s12889-025-22881-3 · Cited by 34 · see citing works

Ginsenoside Rg3 Decreases Fibrotic and Invasive Nature of Endometriosis by Modulating miRNA-27b: In Vitro and In Vivo Studies

Kim, M. K., Lee, S. K., Park, J. H., Lee, J. H., Yun, B. H., Park, J. H., Seo, S. K., Cho, S., & Choi, Y. S. (2017) · Scientific Reports · doi:10.1038/s41598-017-17956-0 · Cited by 34 · see citing works

FOXP1 enhances fibrosis via activating Wnt/β-catenin signaling pathway in endometriosis.

Shao, X. H., & Wei, X. L. (2018) · Europe PMC (PubMed Central) · Cited by 33 · see citing works

Dose-dependent pro- or anti-fibrotic responses of endometriotic stromal cells to interleukin-1β and tumor necrosis factor α

Matsuzaki, S., Pouly, J. L., & Canis, M. J. (2020) · Scientific Reports · doi:10.1038/s41598-020-66298-x · Cited by 33 · see citing works

Vitamin D and Wnt3A have additive and partially overlapping modulatory effects on gene expression and phenotype in human colon fibroblasts

Ferrer‐Mayorga, G., Niell, N., Cantero, R., González‐Sancho, J. M., del Peso, L., Múñoz, A., & Larriba, M. J. (2019) · Scientific Reports · doi:10.1038/s41598-019-44574-9 · Cited by 30 · see citing works

β-catenin signaling inhibitors ICG-001 and C-82 improve fibrosis in preclinical models of endometriosis

Hirakawa, T., Nasu, K., Miyabe, S., Kouji, H., Katoh, A., Uemura, N., & Narahara, H. (2019) · Scientific Reports · doi:10.1038/s41598-019-56302-4 · Cited by 29 · see citing works

Molecular Mechanisms Underlying the Association between Endometriosis and Ectopic Pregnancy

Załęcka, J., Pankiewicz, K., Issat, T., & Laudański, P. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23073490 · Cited by 29 · see citing works

From 2646 to 15: differentially regulated microRNAs between progenitors from normal myometrium and leiomyoma

Lazzarini, R., Caffarini, M., Carpini, G. D., Ciavattini, A., Primio, R. D., & Orciani, M. (2019) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2019.12.016 · Cited by 27 · see citing works

The role of peripheral nerve signaling in endometriosis

Godin, S. K., Wagner, J. A., Huang, P. S., & Bree, D. (2021) · FASEB BioAdvances · doi:10.1096/fba.2021-00063 · Cited by 27 · see citing works

Circulating miRNAs Related to Epithelial–Mesenchymal Transitions (EMT) as the New Molecular Markers in Endometriosis

Zubrzycka, A., Migdalska‐Sęk, M., Jędrzejczyk, S., & Brzeziańska‐Lasota, E. (2021) · Current Issues in Molecular Biology · doi:10.3390/cimb43020064 · Cited by 26 · see citing works

WEE1 promotes endometriosis via the Wnt/β-catenin signaling pathway

Shi, L., Xue, X., Tian, H., Ye, H., Wang, H., Wang, R., Liu, Y., Zhang, C., Chen, Q., & Sun, L. (2021) · Reproductive Biology and Endocrinology · doi:10.1186/s12958-021-00844-8 · Cited by 26 · see citing works

Hypoxia Promotes Invasion of Endometrial Stromal Cells via Hypoxia-Inducible Factor 1α Upregulation-Mediated β-Catenin Activation in Endometriosis

Xiong, W., Zhang, L., Xiong, Y., Liu, H., & Liu, Y. (2015) · Reproductive Sciences · doi:10.1177/1933719115607999 · Cited by 25 · see citing works

Molecular aspects of endometriosis

Adamyan, L. V., & Aznaurova, Y. B. (2015) · Russian Journal of Human Reproduction · doi:10.17116/repro201521266-77 · Cited by 25 · see citing works

Predictive factors of endometriosis progression into ovarian cancer

Varga, J., Reviczká, A., Háková, H., Švajdler, P., Rabajdová, M., & Ostro, A. (2022) · Journal of Ovarian Research · doi:10.1186/s13048-021-00940-8 · Cited by 24 · see citing works

Endometrial Stem Cells in Farm Animals: Potential Role in Uterine Physiology and Pathology

Lara, E., Rivera, N., Cabezas, J. G., Navarrete, F., Saravia, F., Rodriguez-Alvarez, L., & Castro, F. O. (2018) · Bioengineering · doi:10.3390/bioengineering5030075 · Cited by 22 · see citing works

Endometriotic Peritoneal Fluid Promotes Myofibroblast Differentiation of Endometrial Mesenchymal Stem Cells

Zhang, Z., Suo, L., Chen, Y., Zhu, L., Wan, G., & Han, X. (2019) · Stem Cells International · doi:10.1155/2019/6183796 · Cited by 22 · see citing works

Pyrvinium pamoate induces in-vitro suppression of IL-6 and IL-8 produced by human endometriotic stromal cells

Karamian, A., Paktinat, S., Esfandyari, S., Nazarian, H., Ziai, S. A., Zarnani, A., Salehpour, S., Hosseinirad, H., Karamian, A., & Novin, M. G. (2020) · Human & Experimental Toxicology · doi:10.1177/0960327120964543 · Cited by 22 · see citing works

Synergy between Th1 and Th2 responses during endometriosis: A review of current understanding

Chang, L.-Y., Shan, J., Hou, X., Li, D., & Wang, X.-Q. (2023) · Journal of Reproductive Immunology · doi:10.1016/j.jri.2023.103975 · Cited by 24 · see citing works

In‑vitro models of human endometriosis (Review)

Fan, H. (2019) · Experimental and Therapeutic Medicine · doi:10.3892/etm.2019.8363 · Cited by 20 · see citing works

The vicious cycle of chronic endometriosis and depression—an immunological and physiological perspective

Sherwani, S., Khan, M. W. A., Rajendrasozhan, S., Al-Motair, K. A., Husain, Q., & Khan, W. A. (2024) · Frontiers in Medicine · doi:10.3389/fmed.2024.1425691 · Cited by 19 · see citing works

Curbing Inflammation in Multiple Sclerosis and Endometriosis: Should Mast Cells Be Targeted?

Hart, D. A. (2015) · International Journal of Inflammation · doi:10.1155/2015/452095 · Cited by 19 · see citing works

Reduced Expression of Eukaryotic Translation Initiation Factor 3 Subunit e and Its Possible Involvement in the Epithelial-Mesenchymal Transition in Endometriosis

Cai, X., Shen, M., Liu, X., & Guo, S. (2017) · Reproductive Sciences · doi:10.1177/1933719117702248 · Cited by 19 · see citing works

Insights into the Molecular Mechanisms and Signaling Pathways of Epithelial to Mesenchymal Transition (EMT) in the Pathophysiology of Endometriosis

Hosseinirad, H., Jeong, J., & Barrier, B. F. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26157460 · Cited by 18 · see citing works

Upregulation of miR‑33b promotes endometriosis via inhibition of Wnt/β‑catenin signaling and ZEB1 expression

Zhang, H., Li, G., Sheng, X., & Zhang, S. (2019) · Molecular Medicine Reports · doi:10.3892/mmr.2019.9870 · Cited by 18 · see citing works

LINC01541 overexpression attenuates the 17β-Estradiol-induced migration and invasion capabilities of endometrial stromal cells

Mai, H., Wei, Y.-P., Yin, Y., Huang, S., Lin, H., Liao, Y., Liu, X., Chen, X., Shi, H., Liu, C., et al. (2019) · Systems Biology in Reproductive Medicine · doi:10.1080/19396368.2018.1549290 · Cited by 18 · see citing works

Knockdown of PDIA6 Inhibits Cell Proliferation and Enhances the Chemosensitivity in Gastric Cancer Cells

Yan, C., Song, X., Wang, S., Wang, J., & Li, L. (2020) · Cancer Management and Research · doi:10.2147/cmar.s267711 · Cited by 18 · see citing works

The Role of Platelets in the Pathogenesis and Pathophysiology of Adenomyosis

Guo, S. (2023) · Journal of Clinical Medicine · doi:10.3390/jcm12030842 · Cited by 17 · see citing works

Novel Cancer Chemotherapy Hits by Molecular Topology: Dual Akt and Beta-Catenin Inhibitors

Zanni, R., Gálvez-Llompart, M., Morell, C., Rodríguez‐Henche, N., Díaz‐Laviada, I., Recio-Iglesias, M. C., García‐Domenech, R., & Gálvez, J. (2015) · PLoS ONE · doi:10.1371/journal.pone.0124244 · Cited by 16 · see citing works

Activated Platelets Induce Hypoxia-Inducible Factor-1α Expression Likely through Transforming Growth Factor-β1 in Human Endometrial Stromal Cells

Qi, Q.-M., Guo, S.-W., & Liu, X.-S. (2019) · Reproductive and Developmental Medicine · doi:10.4103/2096-2924.262390 · Cited by 15 · see citing works

Endometriosis Stem Cells as a Possible Main Target for Carcinogenesis of Endometriosis-Associated Ovarian Cancer (EAOC)

Wilczyński, J. R., Szubert, M., Paradowska, E., & Wilczyński, M. (2022) · Cancers · doi:10.3390/cancers15010111 · Cited by 15 · see citing works

Ovarian cancer in endometriosis: clinical and molecular aspects.

Lyttle, B., Bernardi, L. A., & Pavone, M. E. (2014) · PubMed · Cited by 15 · see citing works

Relaxin-2 May Suppress Endometriosis by Reducing Fibrosis, Scar Formation, and Inflammation

Yoshino, O., Ono, Y., Honda, M., Hattori, K., Sato, E., Hiraoka, T., Ito, M., Kobayashi, M., Arai, K., Katayama, H., et al. (2020) · Biomedicines · doi:10.3390/biomedicines8110467 · Cited by 14 · see citing works

Impact of Pelvic Pain and Endometriosis on Patient-Reported Outcomes and Experiences of Benign Hysterectomy: A Study from the Swedish National Register for Gynecological Surgery

Grundström, H., Alehagen, S., Berterö, C., & Kjølhede, P. (2017) · Journal of Women s Health · doi:10.1089/jwh.2017.6546 · Cited by 14 · see citing works

Uncovering Potential Roles of Differentially Expressed Genes, Upstream Regulators, and Canonical Pathways in Endometriosis Using an In Silico Genomics Approach

Mirza, Z., & Abdel-dayem, U. A. (2020) · Diagnostics · doi:10.3390/diagnostics10060416 · Cited by 14 · see citing works

Stem Cell Markers Describe a Transition From Somatic to Pluripotent Cell States in a Rat Model of Endometriosis

Othman, E. R., Meligy, F. Y., Sayed, A. A.-R., El‐Mokhtar, M. A., & Refaiy, A. M. (2017) · Reproductive Sciences · doi:10.1177/1933719117697124 · Cited by 13 · see citing works

Effects of U0126 and MK2206 on cell growth and re-growth of endometriotic stromal cells grown on substrates of varying stiffness

Matsuzaki, S., Pouly, J. L., & Canis, M. J. (2017) · Scientific Reports · doi:10.1038/srep42939 · Cited by 12 · see citing works

Identifying novel potential drug targets for endometriosis via plasma proteome screening

Tao, T., Mo, X., & Zhao, L. (2024) · Frontiers in Endocrinology · doi:10.3389/fendo.2024.1416978 · Cited by 11 · see citing works

Characterizing the Extracellular Matrix Transcriptome of Endometriosis

Cook, C. J., Wiggin, N., & Fogg, K. C. (2023) · Reproductive Sciences · doi:10.1007/s43032-023-01359-w · Cited by 11 · see citing works

Wenshen Xiaozheng Tang induces apoptosis and inhibits migration of ectopic endometriotic stromal cells

Zhang, Z., Cheng, X., Gui, T., Tao, J., Huang, M., Zhu, L., Luo, M., Cao, P., & Wan, G. (2016) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2016.07.019 · Cited by 9 · see citing works

A Review of miR-326 and Female Related Diseases

Lin, L., Zhang, Q., Ge, Y., Luo, B., & Xie, X. (2021) · ACTA HISTOCHEMICA ET CYTOCHEMICA · doi:10.1267/ahc.20-00027 · Cited by 9 · see citing works

Experimental modeling, prevention, and treatment of endometriosis-associated adhesion formation in NIH/3T3 fibroblast cell line using bovhyaluronidase azoximer (in vitro)

Adamyan, L. V., Pivazyan, L. G., Mailova, K. S., Peshkova, I. O., & Stepanian, A. A. (2024) · Russian Journal of Human Reproduction · doi:10.17116/repro20243006161 · Cited by 8 · see citing works

Advancements in Ultrasound Diagnosis of Superficial Endometriosis: Current Challenges and Emerging Techniques

Freger, S. M., & Leonardi, M. (2025) · Gynecologic and Obstetric Investigation · doi:10.1159/000543075 · Cited by 9 · see citing works

Blocking CCN2 Reduces Established Palmar Neuromuscular Fibrosis and Improves Function Following Repetitive Overuse Injury

Lambi, A. G., DeSante, R. J., Patel, P. R., Hilliard, B. A., Popoff, S. N., & Barbe, M. F. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms241813866 · Cited by 7 · see citing works

Etiopathogenesis of endometriosis-associated infertility (a review)

Adamyan, L. V., Martirosyan, Y. O., & Asaturova, A. V. (2018) · Russian Journal of Human Reproduction · doi:10.17116/repro201824228-33 · Cited by 7 · see citing works

Endometriosis of Extra-Abdominal Soft Tissues

Wang, J., Strauß, D., Messiou, C., & Thway, K. (2016) · International Journal of Surgical Pathology · doi:10.1177/1066896916644322 · Cited by 7 · see citing works

Early maternal separation accelerates the progression of endometriosis in adult mice

Long, Q., Liu, X., & Guo, S. (2020) · Reproductive Biology and Endocrinology · doi:10.1186/s12958-020-00600-4 · Cited by 7 · see citing works

Pyrvinium pamoate inhibits proliferation and invasion of human endometriotic stromal cells

Karamian, A., Nazarian, H., Ziai, S. A., Zarnani, A. H., Salehpour, S., Paktinat, S., & Novin, M. (2019) · Human & Experimental Toxicology · doi:10.1177/0960327119896612 · Cited by 7 · see citing works

Vascular endothelial growth factor receptor-2 inhibitor cediranib causes regression of endometriotic lesions in a rat model.

Liu, F., Wang, L., Zhang, X.-X., Min, S.-Y., Liu, Y.-X., Zuo, Z., Jin, Z., & Zhu, Z. (2015) · Europe PMC (PubMed Central) · Cited by 7 · see citing works

N-cadherin mechanosensing in ovarian follicles controls oocyte maturation and ovulationPreprint

Emery, A., Blaschuk, O. W., Dinh, D. T., McPhee, T. R., Becker, R., Abell, A. D., Mrozik, K. M., Zannettino, A. C. W., Robker, R. L., & Russell, D. L. (2024) · eLife · doi:10.7554/elife.92068 · Cited by 7 · see citing works

Involvement of the Wnt/β-Catenin Signaling Pathway in the Cellular and Molecular Mechanisms of Fibrosis in

Matsuzaki, S., & Darcha, C. (2016)

FOXP1 enhances fibrosis via activating Wnt/β-catenin signaling pathway in endometriosis.

Shao, X. H., & Wei, X. L. (2018) · Europe PMC (PubMed Central) · Cited by 33 · see citing works

Endometriotic mesenchymal stem cells significantly promote fibrogenesis in ovarian endometrioma through the Wnt/β-catenin pathway by paracrine production of TGF-β1 and Wnt1

Li, J., Dai, Y., Zhu, H., Jiang, Y., & Zhang, S. (2016) · Human Reproduction · doi:10.1093/humrep/dew058 · Cited by 55 · see citing works

CCN5 negatively regulates TGF-β-induced endometriosis associated fibrosis through Wnt/β-catenin signaling via Smad3-dependent mechanism

Liu, M., Gong, Y., Cai, H., Hua, R., Li, H., Wang, Z., Zhou, Y., Ma, Y., & Quan, S. (2025) · Journal of Translational Medicine · doi:10.1186/s12967-025-06804-9 · Cited by 9 · see citing works

In Vitro Effects of a Small-Molecule Antagonist of the Tcf/ß-Catenin Complex on Endometrial and Endometriotic Cells of Patients with Endometriosis

Matsuzaki, S., & Darcha, C. (2013) · PLoS ONE · doi:10.1371/journal.pone.0061690 · Cited by 72 · see citing works