Circulating microRNA profile throughout the menstrual cycle
Open accessAbstract
Normal physiological variables, such as age and gender, contribute to alterations in circulating microRNA (miRNA) expression levels. The changes in the female body during the menstrual cycle can also be reflected in plasma miRNA expression levels. Therefore, this study aimed to determine the plasma miRNA profile of healthy women during the menstrual cycle and to assess which circulating miRNAs are derived from blood cells. The plasma miRNA expression profiles in nine healthy women were determined by quantitative real time PCR using Exiqon Human Panel I assays from four time-points of the menstrual cycle. This platform was also used for studying miRNAs from pooled whole blood RNA samples at the same four time-points. Our results indicated that circulating miRNA expression levels in healthy women were not significantly altered by the processes occurring during the menstrual cycle. No significant differences in plasma miRNA expression levels were observed between the menstrual cycle time-points, but the number of detected miRNAs showed considerable variation among the studied individuals. miRNA analysis from whole blood samples revealed that majority of miRNAs in plasma are derived from blood cells. The most abundant miRNA in plasma and blood was hsa-miR-451a, but a number of miRNAs were only detected in one or the other sample type. In conclusion, our data suggest that the changes in the female body during the menstrual cycle do not affect the expression of circulating miRNAs at measurable levels.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
A few miRNAs were reported to fluctuate during circadian rhythm, menstrual cycle, or exercise.
“A few miRNAs were reported to fluctuate during circadian rhythm30, menstrual cycle35 or exercise36.”
From Intra- and Inter-individual Variability of microRNA Levels in Human Cerebrospinal Fluid: Critical Implications for Biomarker Discovery (2017) · cites this paper as [35]
MicroRNA expression in normal endometrium exhibits dynamic changes across the menstrual cycle.
“MicroRNA expression in normal endometrium exhibits dynamic changes across the menstrual cycle (105), where their involvement in nonpathologic mechanisms can be used to understand physiologic systems that have derailed into pathologic phenotypes.”
From Biomarkers in endometriosis: Challenges and opportunities (2017) · cites this paper as [105]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
1 retracted
Pan, Q., Luo, X., Toloubeydokhti, T., & Chegini, N. (2007) · Molecular Human Reproduction · doi:10.1093/molehr/gam063 · Cited by 261 · see citing works
RetractedAnalysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method
Livak, K. J., & Schmittgen, T. D. (2001) · Methods · doi:10.1006/meth.2001.1262 · Cited by 180,860 · see citing works
Bartel (2004) · doi:10.1016/s0092-8674(04)00045-5 · Cited by 34,714 · see citing works
Valadi, H., Ekström, K., Bossios, A., Sjöstrand, M., Lee, J. J., & Lötvall, J. O. (2007) · Nature Cell Biology · doi:10.1038/ncb1596 · Cited by 12,834 · see citing works
Circulating microRNAs as stable blood-based markers for cancer detection
Mitchell, P. S., Parkin, R. K., Kroh, E. M., Fritz, B. R., Wyman, S. K., Pogosova-Agadjanyan, E. L., Peterson, A., Noteboom, J., O'Briant, K. C., Allen, A., et al. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0804549105 · Cited by 7,969 · see citing works
Chen, X., Ba, Y., Ma, L., Cai, X., Yin, Y., Wang, K., Guo, J., Zhang, Y., Chen, J., Guo, X., et al. (2008) · Cell Research · doi:10.1038/cr.2008.282 · Cited by 4,560 · see citing works
Characterization of extracellular circulating microRNA
Turchinovich, A., Weiz, L., Langheinz, A., & Burwinkel, B. (2011) · Nucleic Acids Research · doi:10.1093/nar/gkr254 · Cited by 1,941 · see citing works
MicroRNA Signatures in Human Ovarian Cancer
Iorio, M. V., Visone, R., Leva, G. D., Donati, V. L., Petrocca, F., Casalini, P., Taccioli, C., Volinia, S., Liu, C.-G., Alder, H., et al. (2007) · Cancer Research · doi:10.1158/0008-5472.can-07-1936 · Cited by 1,396 · see citing works
A novel and universal method for microRNA RT-qPCR data normalization
Mestdagh, P., Van Vlierberghe, P., De Weer, A., Muth, D., Westermann, F., Speleman, F., & Vandesompele, J. (2009) · Genome Biology · doi:10.1186/gb-2009-10-6-r64 · Cited by 924 · see citing works
Blood Cell Origin of Circulating MicroRNAs: A Cautionary Note for Cancer Biomarker Studies
Pritchard, C. C., Kroh, E., Wood, B., Arroyo, J. D., Dougherty, K. J., Miyaji, M. M., Tait, J. F., & Tewari, M. (2012) · Cancer Prevention Research · doi:10.1158/1940-6207.capr-11-0370 · Cited by 879 · see citing works
Salivary microRNA: Discovery, Characterization, and Clinical Utility for Oral Cancer Detection
Park, N. J., Zhou, H., Elashoff, D. A., Henson, B. S., Kastratović, D. A., Abemayor, E., & Wong, D. T. (2009) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-09-0736 · Cited by 845 · see citing works
Comparing the MicroRNA Spectrum between Serum and Plasma
Wang, K., Yuan, Y., Cho, J., McClarty, S., Baxter, D. H., & Galas, D. J. (2012) · PLoS ONE · doi:10.1371/journal.pone.0041561 · Cited by 657 · see citing works
Hanke, M., Hoefig, K. P., Merz, H., Feller, A. C., Kausch, I., Jocham, D., Warnecke, J. M., & Sczakiel, G. (2009) · Urologic Oncology Seminars and Original Investigations · doi:10.1016/j.urolonc.2009.01.027 · Cited by 638 · see citing works
Haemolysis during sample preparation alters microRNA content of plasma
Kirschner, M. B., Kao, S. C., Edelman, J. J., Armstrong, N. J., Vallely, M. P., van Zandwijk, N., & Reid, G. (2011) · PLoS ONE · doi:10.1371/journal.pone.0024145 · Cited by 498 · see citing works
Circulating microRNAs: Association with disease and potential use as biomarkers
Reid, G., Kirschner, M. B., & van Zandwijk, N. (2010) · Critical Reviews in Oncology/Hematology · doi:10.1016/j.critrevonc.2010.11.004 · Cited by 465 · see citing works
Sabapatha, A., Gercel‐Taylor, C., & Taylor, D. D. (2006) · American Journal of Reproductive Immunology · doi:10.1111/j.1600-0897.2006.00435.x · Cited by 333 · see citing works
The role of microRNAs in endometriosis and associated reproductive conditions
Ohlsson Teague, E. M. C., Print, C. G., & Hull, M. L. (2010) · Human Reproduction Update · doi:10.1093/humupd/dmp034 · Cited by 309 · see citing works
Impact of Cellular miRNAs on Circulating miRNA Biomarker Signatures
Duttagupta, R., Jiang, R., Gollub, J., Getts, R. C., & Jones, K. W. (2011) · PLoS ONE · doi:10.1371/journal.pone.0020769 · Cited by 307 · see citing works
Kuokkanen, S., Chen, B., Ojalvo, L., Benard, L., Santoro, N., & Pollard, J. W. (2010) · Biology of Reproduction · doi:10.1095/biolreprod.109.081059 · Cited by 288 · see citing works
The efficiency of pooling mRNA in microarray experiments
Kendziorski, C. M. (2003) · Biostatistics · doi:10.1093/biostatistics/4.3.465 · Cited by 258 · see citing works
Wu, X., Somlo, G., Yu, Y., Palomares, M. R., Li, A. X., Zhou, W., Chow, A. Y., Yen, Y., Rossi, J. J., Gao, H., et al. (2012) · Journal of Translational Medicine · doi:10.1186/1479-5876-10-42 · Cited by 247 · see citing works
The Genomic Analysis of Erythrocyte microRNA Expression in Sickle Cell Diseases
Chen, S., Wang, Y., Telen, M. J., & Chi, J. (2008) · PLoS ONE · doi:10.1371/journal.pone.0002360 · Cited by 198 · see citing works
Identification of miRNAs associated with the follicular–luteal transition in the ruminant ovary
McBride, D., Carré, W., Sontakke, S. D., Hogg, C. O., Law, A., Donadeu, F. X., & Clinton, M. (2012) · Reproduction · doi:10.1530/rep-12-0025 · Cited by 198 · see citing works
Wang, W.-T., Zhao, Y.-N., Han, B.-W., Hong, S.-J., & Chen, Y.-Q. (2013) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2012-2415 · Cited by 193 · see citing works
MicroRNAs miR-30b, miR-30d, and miR-494 Regulate Human Endometrial Receptivity
Altmäe, S., Martínez-Conejero, J. A., Esteban, F. J., Ruíz-Alonso, M., Stavreus-Evers, A. C., Horcajadas, J. A., & Salumets, A. (2012) · Reproductive Sciences · doi:10.1177/1933719112453507 · Cited by 190 · see citing works
Plasma miR-17-5p, miR-20a and miR-22 are down-regulated in women with endometriosis
Jia, S.-Z., Yang, Y., Lang, J., Sun, P., & Leng, J. (2013) · Human Reproduction · doi:10.1093/humrep/des413 · Cited by 172 · see citing works
Plasma Components Affect Accuracy of Circulating Cancer-Related MicroRNA Quantitation
Kim, D.-J., Linnstaedt, S. D., Palma, J., Park, J. C., Ntrivalas, E. I., Kwak-Kim, J. Y.-H., Gilman‐Sachs, A., Beaman, K. D., Hastings, M. L., Martin, J. N., et al. (2011) · Journal of Molecular Diagnostics · doi:10.1016/j.jmoldx.2011.09.002 · Cited by 171 · see citing works
Population differences in microRNA expression and biological implications
Huang, R. S., Gamazon, E. R., Ziliak, D., Wen, Y., Im, H. K., Zhang, W., Wing, C., Duan, S., Bleibel, W. K., Cox, N. J., et al. (2011) · RNA Biology · doi:10.4161/rna.8.4.16029 · Cited by 171 · see citing works
Expression profile of mammalian microRNAs in endometrioid adenocarcinoma
Wu, W., Lin, Z., Zhuang, Z., & Liang, X. (2008) · European Journal of Cancer Prevention · doi:10.1097/cej.0b013e328305a07a · Cited by 167 · see citing works
Circulating MicroRNA Is a Biomarker of Pediatric Crohn Disease
Zahm, A. M., Thayu, M., Hand, N. J., Horner, A. M., Leonard, M. B., & Friedman, J. R. (2011) · Journal of Pediatric Gastroenterology and Nutrition · doi:10.1097/mpg.0b013e31822200cc · Cited by 165 · see citing works
MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing.
Ahn, H., Morin, R. D., Zhao, H., Harris, R. A., Coarfa, C., Chen, Z.-J., Milosavljevic, A., Marra, M., & Rajkovic, A. (2010) · Molecular human reproduction · doi:10.1093/molehr/gaq017 · Cited by 149 · see citing works
MicroRNA 135 regulates HOXA10 expression in endometriosis
Petracco, R., Grechukhina, O., Popkhadze, S., Massasa, E., Zhou, Y., & Taylor, H. S. (2011) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2011-1231 · Cited by 138 · see citing works
Sha, A., Liu, J., Jiang, X., Ren, J., Ma, C.-H., Lei, W., Su, R., & Yang, Z. (2011) · Fertility and Sterility · doi:10.1016/j.fertnstert.2011.04.072 · Cited by 104 · see citing works
Circulating MicroRNA miR-323-3p as a Biomarker of Ectopic Pregnancy
Zhao, Z., Zhao, Q., Warrick, J. I., Lockwood, C. M., Woodworth, A. L., Moley, K. H., & Gronowski, A. M. (2012) · Clinical Chemistry · doi:10.1373/clinchem.2011.179283 · Cited by 100 · see citing works
MicroRNA signatures differentiate uterine cancer tumor subtypes
Ratner, E., Tuck, D. P., Richter, C. E., Nallur, S. V., Patel, R., Schultz, V., Hui, P., Schwartz, P. E., Rutherford, T., & Weidhaas, J. B. (2010) · Gynecologic Oncology · doi:10.1016/j.ygyno.2010.05.010 · Cited by 93 · see citing works
A Parallel Study of mRNA and microRNA Profiling of Peripheral Blood in Young Adult Women
Sredni, S. T., Gadd, S., Jafari, N., & Huang, C. (2011) · Frontiers in Genetics · doi:10.3389/fgene.2011.00049 · Cited by 24 · see citing works
Rhodes, W. (2012) · Journal of Translational Medicine · doi:10.1186/1479-5876-10-s2-a42 · Cited by 5 · see citing works
Ebbel, E. E., & Katz, A. (2011) · Fertility and Sterility · doi:10.1016/j.fertnstert.2011.07.591 · Cited by 1 · see citing works
Flagged first, then by citations
1 of the 39 references couldn’t be matched to a known paper.
Cited by
Sorted by citations
Biomarkers in endometriosis: Challenges and opportunities
Ahn, S. H., Singh, V., & Tayade, C. (2017) · Fertility and Sterility · doi:10.1016/j.fertnstert.2017.01.009 · Cited by 242 · see citing works
Circulating microRNAs as potential biomarkers for endometriosis
Cho, S., Mutlu, L., Grechukhina, O., & Taylor, H. S. (2015) · Fertility and Sterility · doi:10.1016/j.fertnstert.2015.02.013 · Cited by 181 · see citing works
Non-coding RNAs in endometriosis: a narrative review
Panir, K., Schjenken, J. E., Robertson, S. A., & Hull, M. L. (2018) · Human Reproduction Update · doi:10.1093/humupd/dmy014 · Cited by 151 · see citing works
Agrawal, S., Tapmeier, T. T., Rahmioğlu, N., Kirtley, S., Zondervan, K. T., & Becker, C. M. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19020599 · Cited by 132 · see citing works
Measurements Methods for the Development of MicroRNA-Based Tests for Cancer Diagnosis
Precazzini, F., Detassis, S., Imperatori, A. S., Denti, M. A., & Campomenosi, P. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22031176 · Cited by 89 · see citing works
The role of epigenetic mechanisms in the regulation of gene expression in the cyclical endometrium
Retis-Resendiz, A. M., González-García, I. N., León‐Juárez, M., Camacho‐Arroyo, I., Cerbón, M. A., & Vázquez-Martínez, E. R. (2021) · Clinical Epigenetics · doi:10.1186/s13148-021-01103-8 · Cited by 81 · see citing works
The Importance of Standardization on Analyzing Circulating RNA
Lee, I., Baxter, D. H., Lee, M. Y., Scherler, K., & Wang, K. (2016) · Molecular Diagnosis & Therapy · doi:10.1007/s40291-016-0251-y · Cited by 70 · see citing works
miRNAs Regulation and Its Role as Biomarkers in Endometriosis
Marí‐Alexandre, J., Sánchez-Izquierdo, D., Gilabert–Estellés, J., Barceló‐Molina, M., Braza‐Boïls, A., & Sandoval, J. (2016) · International Journal of Molecular Sciences · doi:10.3390/ijms17010093 · Cited by 71 · see citing works
Qattan, A. T., Intabli, H., Alkhayal, W., Eltabache, C., Taher, T., & Amer, S. M. B. (2017) · BMC Cancer · doi:10.1186/s12885-017-3776-5 · Cited by 68 · see citing works
Traver, S., Assou, S., Scalici, E., Haouzi, D., Al-Edani, T., Belloc, S., & Hamamah, S. (2014) · Human Reproduction Update · doi:10.1093/humupd/dmu031 · Cited by 66 · see citing works
Plasma miRNAs Display Limited Potential as Diagnostic Tools for Endometriosis
Nisenblat, V., Sharkey, D. J., Wang, Z., Evans, S., Healey, M., Teague, E., Print, C. G., Robertson, S. A., & Hull, M. L. (2019) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2018-01464 · Cited by 63 · see citing works
Marí‐Alexandre, J., Barceló‐Molina, M., Belmonte-López, E., García-Oms, J., Estellés, A., Braza‐Boïls, A., & Gilabert–Estellés, J. (2018) · Fertility and Sterility · doi:10.1016/j.fertnstert.2017.11.036 · Cited by 56 · see citing works
Vanhaverbeke, M., Attard, R., Barteková, M., Ben‐Aicha, S., Brandenburger, T., de Gonzalo‐Calvo, D., Emanueli, C., Farrugia, R. C., Grillari, J., Hackl, M., et al. (2021) · Cardiovascular Research · doi:10.1093/cvr/cvab327 · Cited by 54 · see citing works
El‐Daly, S. M., Gouhar, S. A., & Elmageed, Z. Y. A. (2022) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.121.000896 · Cited by 53 · see citing works
Circulating microRNA Profiles during the Bovine Oestrous Cycle
Ioannidis, J., & Donadeu, F. X. (2016) · PLoS ONE · doi:10.1371/journal.pone.0158160 · Cited by 51 · see citing works
Rekker, K., Altmäe, S., Suhorutshenko, M., Peters, M., Martínez-Blanch, J. F., Codoñer, F. M., Vilella, F., Simón, C., Salumets, A., & Velthut‐Meikas, A. (2018) · Genes · doi:10.3390/genes9120574 · Cited by 42 · see citing works
miR-205-5p inhibits human endometriosis progression by targeting ANGPT2 in endometrial stromal cells
Zhou, C.-F., Liu, M.-J., Wang, W., Wu, S., Huang, Y., Chen, G.-B., Liu, L.-M., Peng, D., Wang, X., Cai, X., et al. (2019) · Stem Cell Research & Therapy · doi:10.1186/s13287-019-1388-5 · Cited by 40 · see citing works
Estrogen-regulated miRNA-27b is altered by bisphenol A in human endometrial stromal cells
Reed, B. G., Babayev, S. N., Chen, L. X., Carr, B. R., Word, R. A., & Jimenez, P. T. (2018) · Reproduction · doi:10.1530/rep-18-0041 · Cited by 38 · see citing works
Zafari, N., Tarafdari, A. M., Izadi, P., Noruzinia, M., Yekaninejad, M. S., Bahramy, A., & Mohebalian, A. (2021) · Reproductive Sciences · doi:10.1007/s43032-020-00415-z · Cited by 36 · see citing works
Discordant Expression of Circulating microRNA from Cellular and Extracellular Sources
Shah, R. V., Tanrıverdi, K., Levy, D. A., Larson, M. G., Gerstein, M., Mick, E. O., Rozowsky, J. S., Kitchen, R. R., Murthy, V. L., Mikalev, E., et al. (2016) · PLoS ONE · doi:10.1371/journal.pone.0153691 · Cited by 35 · see citing works
Mooney, C., Raoof, R. M., Naggar, H. E., Sanz‐Rodriguez, A., Jimenez-Mateos, E. M., & Henshall, D. C. (2015) · PLoS ONE · doi:10.1371/journal.pone.0145316 · Cited by 35 · see citing works
Ma, H., Gong, F., Tang, Y., Li, X., Li, X., Yang, X., & Lu, G. (2015) · Biology of Reproduction · doi:10.1095/biolreprod.115.128603 · Cited by 32 · see citing works
Zhong, Z., Rosenow, M. A., Xiao, N., & Spetzler, D. B. (2018) · Journal of Extracellular Vesicles · doi:10.1080/20013078.2018.1458574 · Cited by 30 · see citing works
Circulating MicroRNAs: Methodological Aspects in Detection of These Biomarkers
Hruštincová, A., Votavová, H., & Merkerová, M. D. (2015) · Folia Biologica · doi:10.14712/fb2015061060203 · Cited by 28 · see citing works
Yoon, H., Belmonte, K. C., Kasten, T., Bateman, R., & Kim, J. (2017) · Scientific Reports · doi:10.1038/s41598-017-13031-w · Cited by 26 · see citing works
Hiskens, M. I., Mengistu, T. S., Li, K. M., & Fenning, A. S. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms232113160 · Cited by 29 · see citing works
Holtkötter, H., Schwender, K., Wiegand, P., Peiffer, H., & Vennemann, M. (2017) · International Journal of Legal Medicine · doi:10.1007/s00414-017-1724-1 · Cited by 26 · see citing works
The role of the serum exosomal and endometrial microRNAs in recurrent implantation failure
Azhari, F., Pençe, S., Hosseini, M. K., Balcı, B. K., Çevik, N., Baştu, E., & Günel, T. (2020) · The Journal of Maternal-Fetal & Neonatal Medicine · doi:10.1080/14767058.2020.1849095 · Cited by 22 · see citing works
The effect of the menstrual cycle on the circulating microRNA pool in human plasma: a pilot study
Lamon, S., Carré, J. L., Petito, G., Duong, H. P., Lüthi, F., Hiam, D., & Léger, B. (2022) · Human Reproduction · doi:10.1093/humrep/deac243 · Cited by 21 · see citing works
MicroRNAs as Biomarkers and Therapeutic Targets in Female Infertility
Chico-Sordo, L., & García-Velasco, J. A. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms252312979 · Cited by 19 · see citing works
Breast Cancer Response to Therapy: Can microRNAs Lead the Way?
Petrović, N., Nakashidze, I., & Nedeljković, M. (2021) · Journal of Mammary Gland Biology and Neoplasia · doi:10.1007/s10911-021-09478-3 · Cited by 16 · see citing works
Chemonges, S., Tung, J., & Fraser, J. F. (2014) · Proteome Science · doi:10.1186/1477-5956-12-12 · Cited by 14 · see citing works
Dini, P., Loux, S. C., Scoggin, K. E. S., Esteller‐Vico, A., Squires, E. L., Troedsson, M. H. T., Daels, P. F., & Ball, B. A. (2017) · Molecular Biotechnology · doi:10.1007/s12033-017-0047-2 · Cited by 14 · see citing works
miRNAs: Perspective towards the use for body fluid identification
Praihirunkit, P. (2020) · Siriraj Medical Journal/San Sirirat · doi:10.33192/smj.2020.70 · Cited by 10 · see citing works
Insenser, M. R., Quintero, A., Quiñones, S. D. L., Álvarez-Blasco, F., Martínez-García, M. Á., Luque‐Ramírez, M., & Escobar-Morreale, H. F. (2023) · Human Reproduction · doi:10.1093/humrep/dead043 · Cited by 8 · see citing works
Timmermans, S., Hauwermeiren, F. V., Puimège, L., Dejager, L., Wonterghem, E. V., Vanhooren, V., Mestdagh, P., Libert, C., & Vandenbroucke, R. E. (2014) · Mammalian Genome · doi:10.1007/s00335-014-9550-y · Cited by 7 · see citing works
MacGregor, K. A., Rodríguez-Sánchez, N., Virgilio, T. G. D., Barwell, N. D., Gallagher, I. J., & Moran, C. N. (2021) · Physiological Genomics · doi:10.1152/physiolgenomics.00088.2021 · Cited by 7 · see citing works
Role of microRNAs in embryo–endometrial interactions: biological functions and clinical applications
Qi, S., Kodithuwakku, S., Pang, R. T., Chiu, P. C. N., Tang, M. Y., & Lee, K.-F. (2023) · Reproductive and Developmental Medicine · doi:10.1097/rd9.0000000000000073 · Cited by 6 · see citing works
Vaidyanathan, V., Krishnamoorthy, V., Karunasinghe, N., Jabed, A., Pallati, R., Kao, C., Wang, A., Marlow, G., & Ferguson, L. R. (2016) · Non-Coding RNA · doi:10.3390/ncrna2020002 · Cited by 4 · see citing works
Acides nucléiques circulants et fécondation in vitro
Scalici, E., Traver, S., Mullet, T., Ferrières, A., Monforte, M., Vintéjoux, E., & Hamamah, S. (2014) · Gynécologie Obstétrique & Fertilité · doi:10.1016/j.gyobfe.2014.07.014 · Cited by 5 · see citing works
Sapp, R. M., Landers‐Ramos, R. Q., Shill, D. D., Springer, C. B., & Hagberg, J. M. (2020) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00292.2020 · Cited by 5 · see citing works
miRNA in Endometriosis—A New Hope or an Illusion?
Dryja-Brodowska, A., Obrzut, B., Obrzut, M., & Darmochwał-Kolarz, D. (2025) · Journal of Clinical Medicine · doi:10.3390/jcm14144849 · Cited by 4 · see citing works
MicroRNAs as Next Generation Therapeutics in Osteoporosis
Kaur, T., Kapila, R., & Kapila, S. (2020) · IntechOpen eBooks · doi:10.5772/intechopen.91223 · Cited by 4 · see citing works
Clinical Implementation of Bone Regeneration and Maintenance
Barbeck, M., Rosenberg, N., Kačarević, Ž. P., Jung, O., & Rider, P. (2019) · IntechOpen eBooks · doi:10.5772/intechopen.85328 · Cited by 4 · see citing works
Serum miRNA-based diagnostic models for endometriosis: from discovery to validation
Ravaggi, A., Bergamaschi, C., Conforti, J., Ciravolo, G., Zanotti, L., Fabricio, A. S. C., Gion, M., Cappelletto, E., Leon, A. E., Rossetti, D. O., et al. (2025) · Human Reproduction · doi:10.1093/humrep/deaf221 · Cited by 4 · see citing works
Okamoto, K., Sone, M., Taura, D., Ohno, Y., Yamauchi, I., Ueda, Y., Hakata, T., Tsuiki, M., Murakami, M., Yabe, D., et al. (2025) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/clinem/dgaf408 · Cited by 3 · see citing works
Differential microRNA expression in adolescent anxiety proneness
van Rensburg, D. J., Womersley, J. S., Martin, L. I., Seedat, S., & Hemmings, S. M. J. (2024) · European Journal of Neuroscience · doi:10.1111/ejn.16523 · Cited by 2 · see citing works
miRNA expression haplotype in Hispanics with endometriosis
Alday-Montañez, F. D., Lariz-Nevárez, B. D., Carrasco-Urrutia, V. J., Dickens-Terrazas, D., Barragán-Farías, A., Mejía-Carmona, G. E., Kirken, R. A., Bencomo-Alvarez, A. E., Lobo-Galo, N., Vargas-Caraveo, A., et al. (2025) · Frontiers in Reproductive Health · doi:10.3389/frph.2025.1663755 · Cited by 1 · see citing works
Circulating Molecular Biomarkers in Thyroid Cancer
Durante, C., Rosignolo, F., Sponziello, M., Verrienti, A., & Filetti, S. (2018) · Springer eBooks · doi:10.1007/978-3-319-62506-5_6 · Cited by 1 · see citing works
Molecular Biology Techniques for Endometrial Gene Expression: Recent Technological Advances
Ni, K., & Ma, L. (2019) · Springer eBooks · doi:10.1007/978-3-030-28584-5_2
Bergström, H., Heiland, C. E., Björkhem‐Bergman, L., & Ekström, L. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.11.05.467468
- Authors
- Rekker, K., Saare, M., Roost, A. M., Salumets, A., & Peters, M.
- Affiliations
- Competence Centre on Health Technologies (Estonia) (EE)
- Corresponding author
- Rekker, Kadri
- Venue
- PLoS ONE
- Publisher
- Public Library of Science (PLoS)
- Published
- 2013-11-14
- Volume
- 8
- Issue
- 11
- Pages
- e81166
- ISSN
- 1932-6203 (ISSN-L)
- PMC
- PMC3828277
- OpenAlex
- W2071871693
- Cited by
- 52
- References
- 39
- Citations by year
- 2025: 4 · 2024: 2 · 2023: 2 · 2022: 3 · 2021: 7 · 2020: 4 · 2019: 4 · 2018: 7 · 2017: 6 · 2016: 5 · 2015: 4 · 2014: 4
- FWCI
- 1.52
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- PLoS ONE (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Figshare (submittedVersion, cc-by)
- Funders
- Ettevõtluse Arendamise Sihtasutus (EU30020, SF0180044s09)
- European Regional Development Fund (EU30020)
- Eurostars
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cancer Research › MicroRNA in disease regulation
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Extracellular vesicles in disease
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Plant Molecular Biology Research
- Keywords
- circulating microRNAs, menstrual cycle, plasma microRNA expression, whole blood RNA, healthy women, biomarkers
- MeSH terms
- Adult, Female, Humans, Menstrual Cycle, Gene Expression Profiling, MicroRNAs, Young Adult, Real-Time Polymerase Chain Reaction
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
