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Association between APOC1 Polymorphism and Alzheimer’s Disease: A Case-Control Study and Meta-Analysis
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These variants have been reported in previous studies to exhibit strong associations with AD risk.
“and have been reported in previous studies to exhibit strong associations with AD risk [4, 12, 77–80].”
From Association of APOC1 with cortical atrophy during conversion to Alzheimer’s disease (2025) · cites this paper as [4]
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Systematic meta-analyses of Alzheimer disease genetic association studies: the AlzGene database
Bertram, L., McQueen, M. B., Mullin, K., Blacker, D., & Tanzi, R. E. (2007) · Nature Genetics · doi:10.1038/ng1934 · Cited by 1,857
Expression of Novel Alzheimer’s Disease Risk Genes in Control and Alzheimer’s Disease Brains
Karch, C. M., Jeng, A. T., Nowotny, P., Cady, J., Cruchaga, C., & Goate, A. M. (2012) · PLoS ONE · doi:10.1371/journal.pone.0050976 · Cited by 328
Apolipoprotein CI Knock-Out Mice Display Impaired Memory Functions
Berbée, J. F. P., Vanmierlo, T., Abildayeva, K., Blokland, A., Jansen, P. J., Lütjohann, D., Gautier, T., Sijbrands, E., Prickaerts, J., Hadfoune, M., et al. (2011) · Journal of Alzheimer's Disease · doi:10.3233/jad-2010-100576 · Cited by 25
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Research works printed but not linked: 29
- HP Qi, 2012, IL-6-174 G/C and -572 C/G polymorphisms and risk of Alzheimer's disease, PLoS One, 7, e37858, 10.1371/journal.pone.0037858 · DOI
- N Takei, 2009, Genetic association study on in and around the APOE in late-onset Alzheimer disease in Japanese, Genomics, 93, 441, 10.1016/j.ygeno.2009.01.003 · DOI
- WJ Devan, 2013, Heritability estimates identify a substantial genetic contribution to risk and outcome of intracerebral hemorrhage, Stroke, 44, 1578, 10.1161/STROKEAHA.111.000089 · DOI
- P Olgiati, 2012, Association of SORL1 alleles with late-onset Alzheimer's disease. findings from the GIGAS_LOAD study and mega-analysis, Curr Alzheimer Res, 9, 491, 10.2174/156720512800492431 · DOI
- S Majumder, 2011, Inducing autophagy by rapamycin before, but not after, the formation of plaques and tangles ameliorates cognitive deficits, PLoS One, 6, e25416, 10.1371/journal.pone.0025416 · DOI · Paper page
- V Leduc, 2010, APOE and cholesterol homeostasis in Alzheimer's disease, Trends Mol Med, 16, 469, 10.1016/j.molmed.2010.07.008 · DOI
- M Vestergaard, 2010, Cholesterol, lipids, amyloid Beta, and Alzheimer's, Curr Alzheimer Res, 7, 262, 10.2174/156720510791050821 · DOI
- JF Lucatelli, 2011, Genetic influences on Alzheimer's disease: evidence of interactions between the genes APOE, APOC1 and ACE in a sample population from the South of Brazil, Neurochem Res, 36, 1533, 10.1007/s11064-011-0481-7 · DOI
- CS Ki, 2002, Genetic association of an apolipoprotein C-I (APOC1) gene polymorphism with late-onset Alzheimer's disease, Neurosci Lett, 319, 75, 10.1016/S0304-3940(01)02559-9 · DOI · Paper page
- B Tycko, 2004, APOE and APOC1 promoter polymorphisms and the risk of Alzheimer disease in African American and Caribbean Hispanic individuals, Arch Neurol, 61, 1434, 10.1001/archneur.61.9.1434 · DOI
- C Petit-Turcotte, 2001, Apolipoprotein C-I expression in the brain in Alzheimer's disease, Neurobiol Dis, 8, 953, 10.1006/nbdi.2001.0441 · DOI · Paper page
- JD Yang, 2003, Apolipoprotein E -491 promoter polymorphism is an independent risk factor for Alzheimer's disease in the Chinese population, Neurosci Lett, 350, 25, 10.1016/S0304-3940(03)00815-2 · DOI
- MC Chartier-Harlin, 1994, Apolipoprotein E, epsilon 4 allele as a major risk factor for sporadic early and late-onset forms of Alzheimer's disease: analysis of the 19q13.2 chromosomal region, Hum Mol Genet, 3, 569, 10.1093/hmg/3.4.569 · DOI
- J Shi, 2004, Association between apolipoprotein CI HpaI polymorphism and sporadic Alzheimer's disease in Chinese, Acta Neurol Scand, 109, 140, 10.1034/j.1600-0404.2003.00193.x · DOI
- WL Chuang, 2010, Association of apolipoproteins e4 and c1 with onset age and memory: a study of sporadic Alzheimer disease in Taiwan, J Geriatr Psychiatry Neurol, 23, 42, 10.1177/0891988709351804 · DOI · Paper page
- M Mullan, 1996, Familial and population-based studies of apolipoprotein E and Alzheimer's disease, Ann N Y Acad Sci, 802, 16, 10.1111/j.1749-6632.1996.tb32594.x · DOI
- K Kamino, 1996, Genetic association study between senile dementia of Alzheimer's type and APOE/C1/C2 gene cluster, Gerontology, 42, 12, 10.1159/000213820 · DOI
- E Drigalenko, 1998, Interaction of the apolipoprotein E and CI loci in predisposing to late-onset Alzheimer's disease, Neurology, 51, 131, 10.1212/WNL.51.1.131 · DOI
- R Scacchi, 1999, Plasma levels of apolipoprotein E and genetic markers in elderly patients with Alzheimer's disease, Neurosci Lett, 259, 33, 10.1016/S0304-3940(98)00889-1 · DOI · Paper page
- W Retz, 2001, Potential genetic markers of sporadic Alzheimer's dementia, Psychiatr Genet, 11, 115, 10.1097/00041444-200109000-00002 · DOI · Paper page
- SE Poduslo, 1998, The apolipoprotein CI A allele as a risk factor for Alzheimer's disease, Neurochem Res, 23, 361, 10.1023/A:1022409617539 · DOI
- VC Hachinski, 1975, Cerebral blood flow in dementia, Arch Neurol, 32, 632, 10.1001/archneur.1975.00490510088009 · DOI · Paper page
- VN Loparev, 1991, An efficient and simple method of DNA extraction from whole blood and cell lines to identify infectious agents, J Virol Methods, 34, 105, 10.1016/0166-0934(91)90126-K · DOI
- YY Shi, 2005, SHEsis, a powerful software platform for analyses of linkage disequilibrium, haplotype construction, and genetic association at polymorphism loci, Cell Res, 15, 97, 10.1038/sj.cr.7290272 · DOI
- SL Zheng, 2008, Cumulative association of five genetic variants with prostate cancer, N Engl J Med, 358, 910, 10.1056/NEJMoa075819 · DOI
- CC Liu, 2013, Apolipoprotein E and Alzheimer disease: risk, mechanisms and therapy, Nat Rev Neurol, 9, 106, 10.1038/nrneurol.2012.263 · DOI · Paper page
- C Dou, 2013, The association of ACT -17 A/T polymorphism with Alzheimer's disease: a meta-analysis, Curr Alzheimer Res, 10, 63
- K Abildayeva, 2008, Human apolipoprotein C-I expression in mice impairs learning and memory functions, J Lipid Res, 49, 856, 10.1194/jlr.M700518-JLR200 · DOI · Paper page
- JM Serra-Grabulosa, 2003, Apolipoproteins E and C1 and brain morphology in memory impaired elders, Neurogenetics, 4, 141, 10.1007/s10048-002-0142-8 · DOI · Paper page
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Hersi, M., Irvine, B., Gupta, P., Gomes, J., Birkett, N., & Krewski, D. (2017) · NeuroToxicology · doi:10.1016/j.neuro.2017.03.006 · Cited by 332
Duara, R., & Barker, W. (2022) · Neurotherapeutics · doi:10.1007/s13311-022-01185-z · Cited by 187
Functional Roles of the Interaction of APP and Lipoprotein Receptors
Pohlkamp, T., Wasser, C. R., & Herz, J. (2017) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2017.00054 · Cited by 92
Bae, J., Logan, P. E., Acri, D. J., Bharthur, A., Nho, K., Saykin, A. J., Risacher, S. L., Nudelman, K., Polsinelli, A. J., Pentchev, V., et al. (2023) · Alzheimer's & Dementia · doi:10.1002/alz.13319 · Cited by 14
“37–40 In terms of the interactive effects between SNPs in APOC1 and TOMM40 (Figure S6), Prendecki et al. reported that defects in APOC1 , in addition to the TOMM40 gene, increase oxidative stress and have an APOE ε 4 – independent effect on AD progression.”
BackgroundAssociation of APOC1 with cortical atrophy during conversion to Alzheimer’s disease
Oh, S., Kim, S., Kim, J. P., Seo, S. W., Park, B.-Y., & Park, H. (2025) · GeroScience · doi:10.1007/s11357-025-01695-6 · Cited by 4
Metadata
- Authors
- Zhou, Q., Zhao, F., Lv, Z.-P., Zheng, C.-G., Zheng, W.-D., Sun, L., Wang, N.-N., Pang, S., de Andrade, F. M., Fu, M., He, X.-H., Hui, J., Jiang, W.-Y., Yang, C.-Y., Shi, X.-H., Zhu, X.-Q., Pang, G.-F., Yang, Y.-G., Xie, H.-Q., Zhang, W.-D., Hu, C.-Y., & Yang, Z.
- Venue
- PLoS ONE
- Publisher
- Public Library of Science (PLoS)
- Published
- 2014-01-31
- Volume
- 9
- Issue
- 1
- Pages
- e87017
- ISSN
- 1932-6203
- PMC
- PMC3909044
- Cited by
- 76
- References
- 3
- Language
- en
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