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Maturation of Oral Microbiota in Children with or without Dental Caries

Lif Holgerson, Pernilla, Öhman, Carina, Rönnlund, Agneta, Johansson, Ingegerd·2015·PLOS ONE
DOI 10.1371/journal.pone.0128534PMC PMC4447273
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Figures

Fig 1 Flow chart diagram. Description of number of study participants and dropouts, data collection and analyses and caries status at 3 years of age.
Fig 1 Flow chart diagram. Description of number of study participants and dropouts, data collection and analyses and caries status at 3 years of age.CC BY · PubMed Central
Fig 2 Phyla prevalence. Prevalence at 3-months and 3-years of age of detected phyla.
Fig 2 Phyla prevalence. Prevalence at 3-months and 3-years of age of detected phyla.CC BY · PubMed Central
Fig 3 Genera prevalence. Prevalence at 3-months and 3-years of age of genera detected in >50% of the children at 3 years of age.
Fig 3 Genera prevalence. Prevalence at 3-months and 3-years of age of genera detected in >50% of the children at 3 years of age.CC BY · PubMed Central
Fig 4 Species/phylotype prevalence. Prevalence at 3-months and 3-years of age of species/phylotypes detected in all (100%) of the children at 3 years of age.
Fig 4 Species/phylotype prevalence. Prevalence at 3-months and 3-years of age of species/phylotypes detected in all (100%) of the children at 3 years of age.CC BY · PubMed Central
Fig 5 Species/phylotype prevalence. Prevalence at 3-months and 3-years of age of species/phylotypes detected in >50% but <100% of the children at 3 years of age.
Fig 5 Species/phylotype prevalence. Prevalence at 3-months and 3-years of age of species/phylotypes detected in >50% but <100% of the children at 3 years of age.CC BY · PubMed Central
Fig 6 Rarefaction curves. Curves from children at 3 months and 3 years of age, stratified by caries development at 3 years of age. Comparisons include 11 children with caries, and 11 caries-free children.
Fig 6 Rarefaction curves. Curves from children at 3 months and 3 years of age, stratified by caries development at 3 years of age. Comparisons include 11 children with caries, and 11 caries-free children.CC BY · PubMed Central
Fig 7 PCoA clustering analysis by age. Red dots indicate samples from the 3-month-old infants, and blue dots indicate samples from the 3-year-olds.
Fig 7 PCoA clustering analysis by age. Red dots indicate samples from the 3-month-old infants, and blue dots indicate samples from the 3-year-olds.CC BY · PubMed Central
Fig 8 PCoA clustering analysis by caries status. The upper figure (A) shows the microbiota variation between 3-month-old infants who developed caries at 3 years of age (red dots) and those who did not (blue dots). The lower figure (B) shows the microbiota variation between 3-year-old children who had caries (red dots) and those who did not (blue dots).
Fig 8 PCoA clustering analysis by caries status. The upper figure (A) shows the microbiota variation between 3-month-old infants who developed caries at 3 years of age (red dots) and those who did not (blue dots). The lower figure (B) shows the microbiota variation between 3-year-old children who had caries (red dots) and those who did not (blue dots).CC BY · PubMed Central
Fig 9 Partial least-squares analysis (PLS) of microbiota associated with having caries or not at 3 years of age (A) Scatter-loading plot illustrating clustering of children having caries or being caries-free. (B) Column loading plot illustrating taxa associated with having caries or not (caries-free). The PLS model employed caries and caries-free allocations as y, and pyrosequencing and HOMIM taxa as the x-block.
Fig 9 Partial least-squares analysis (PLS) of microbiota associated with having caries or not at 3 years of age (A) Scatter-loading plot illustrating clustering of children having caries or being caries-free. (B) Column loading plot illustrating taxa associated with having caries or not (caries-free). The PLS model employed caries and caries-free allocations as y, and pyrosequencing and HOMIM taxa as the x-block.CC BY · PubMed Central

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Citations

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Metadata

Authors
Lif Holgerson, P., Öhman, C., Rönnlund, A., & Johansson, I.
Venue
PLOS ONE
Publisher
Public Library of Science (PLoS)
Published
2015-05-28
Volume
10
Issue
5
Pages
e0128534
ISSN
1932-6203
DOI
10.1371/journal.pone.0128534
PMC
PMC4447273
Cited by
97
References
4
Language
en
Licence
creativecommons.org/licenses/by/4.0/ (vor)

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Lif Holgerson, P., Öhman, C., Rönnlund, A., & Johansson, I. (2015). Maturation of Oral Microbiota in Children with or without Dental Caries. PLOS ONE. https://doi.org/10.1371/journal.pone.0128534