The DOI matches its Crossref record; 74 of the 74 references it cites were found in a registry or an index.
The Relationship between Health Literacy and Health Disparities: A Systematic Review
Open accessAbstract
OBJECTIVES: Health literacy is commonly associated with many of the antecedents of health disparities. Yet the precise nature of the relationship between health literacy and disparities remains unclear. A systematic review was conducted to better understand in how far the relationship between health literacy and health disparities has been systematically studied and which potential relationships and pathways have been identified. METHODS: Five databases, including PubMed/MEDLINE and CINAHL, were searched for peer-reviewed studies. Publications were included in the review when they (1) included a valid measure of health literacy, (2) explicitly conceived a health disparity as related to a social disparity, such as race/ethnicity or education and (3) when results were presented by comparing two or more groups afflicted by a social disparity investigating the effect of health literacy on health outcomes. Two reviewers evaluated each study for inclusion and abstracted relevant information. Findings were ordered according to the disparities identified and the role of health literacy in explaining them. RESULTS: 36 studies were included in the final synthesis. Most of the studies investigated racial/ethnic disparities, followed by some few studies that systematically investigated educational disparities. Some evidence was found on the mediating function of health literacy on self-rated health status across racial/ethnic and educational disparities, as well as on the potential effect of health literacy and numeracy on reducing racial/ethnic disparities in medication adherence and understanding of medication intake. CONCLUSION: Overall the evidence on the relationship between health literacy and disparities is still mixed and fairly limited. Studies largely varied with regard to health(-related) outcomes under investigation and the health literacy assessments used. Further, many studies lacked a specific description of the nature of the disparity that was explored and a clear account of possible pathways tested.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Figures



Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The cited source says what the claim attributes to it.
In the citing paper
“Language barriers are not the only issue that contributes to health inequities, and much has been written about these factors that are collectively known as social determinants of health [59-62]”
From Technology enabled clinical care (TECC): Protocol for a prospective longitudinal cohort study of smartphone-augmented mental health treatment (2021) · cites this paper as [61]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Preferred Reporting Items for Systematic Reviews and Meta-Analyses: the PRISMA statement
Moher, D., Liberati, A., Tetzlaff, J., Altman, D. G., & for the PRISMA Group (2009) · BMJ · doi:10.1136/bmj.b2535 · Cited by 83,823
Preferred reporting items for systematic reviews and meta-analyses: the PRISMA Statement.
(2009) · PubMed Central · Cited by 44,859
Preferred reporting items for systematic reviews and meta-analyses: The PRISMA statement
Moher, D., Liberati, A., Tetzlaff, J., Altman, D. G., & the PRISMA Group* (2009) · Annals of Internal Medicine · doi:10.7326/0003-4819-151-4-200908180-00135 · Cited by 37,554
Low Health Literacy and Health Outcomes: An Updated Systematic Review
Berkman, N. D., Sheridan, S. L., Donahue, K. E., Halpern, D. J., & Crotty, K. (2011) · Annals of Internal Medicine · doi:10.7326/0003-4819-155-2-201107190-00005 · Cited by 5,505
Health Literacy: A Prescription to End Confusion
Committee on Health Literacy, Board on Neuroscience and Behavioral Health, & Institute of Medicine (2004) · doi:10.17226/10883 · Cited by 3,444
Quick Assessment of Literacy in Primary Care: The Newest Vital Sign
Weiss, B. (2005) · The Annals of Family Medicine · doi:10.1370/afm.405 · Cited by 2,222
Rapid estimate of adult literacy in medicine: a shortened screening instrument.
Davis, T. C., Long, S. W., Jackson, R. H., Mayeaux, E. J., George, R. B., Murphy, P. W., & Crouch, M. A. (1993) · PubMed · Cited by 1,597
Health disparities and health equity: Concepts and measurement
Braveman, P. (2006) · Annual Review of Public Health · doi:10.1146/annurev.publhealth.27.021405.102103 · Cited by 1,570
Socioeconomic Disparities in Health in the United States: What the Patterns Tell Us
Braveman, P. A., Cubbin, C., Egerter, S., Williams, D. R., & Pamuk, E. (2010) · American Journal of Public Health · doi:10.2105/ajph.2009.166082 · Cited by 1,548
Kutner, M. A., Greenburg, E., Jin, Y., & Paulsen, C. A. (2006) · National Center for Education Statistics · Cited by 1,545
Development of a brief test to measure functional health literacy
Baker, D. W., Williams, M. V., Parker, R. M., Gazmararian, J. A., & Nurss, J. R. (1999) · Patient Education and Counseling · doi:10.1016/s0738-3991(98)00116-5 · Cited by 1,545
Validation of Screening Questions for Limited Health Literacy in a Large VA Outpatient Population
Chew, L. D., Griffin, J. M., Partin, M. R., Noorbaloochi, S., Grill, J. P., Snyder, A., Bradley, K. A., Nugent, S. M., Simon, A. B., & van Ryn, M. (2008) · Journal of General Internal Medicine · doi:10.1007/s11606-008-0520-5 · Cited by 1,432
Functional Health Literacy and the Risk of Hospital Admission Among Medicare Managed Care Enrollees
Baker, D. W., Gazmararian, J. A., Williams, M. V., Scott, T. L., Parker, R. M., Green, D., Ren, J., & Peel, J. L. (2002) · American Journal of Public Health · doi:10.2105/ajph.92.8.1278 · Cited by 1,004
What are Health Disparities and Health Equity? We Need to Be Clear
Braveman, P. (2014) · Public Health Reports® · doi:10.1177/00333549141291s203 · Cited by 860
van der Heide, I., Wang, J., Droomers, M., Spreeuwenberg, P. M. M., Rademakers, J. J. D. J. M., & Uiters, E. (2013) · Journal of Health Communication · doi:10.1080/10810730.2013.825668 · Cited by 857
Kennedy, B. P., Kawachi, I. I., Glass, R. J., & Prothrow‐Stith, D. (1998) · BMJ · doi:10.1136/bmj.317.7163.917 · Cited by 810
Health Literacy and Functional Health Status Among Older Adults
Wolf, M. S., Gazmararian, J. A., & Baker, D. W. (2005) · Archives of Internal Medicine · doi:10.1001/archinte.165.17.1946 · Cited by 787
Functional health literacy and health-promoting behaviour in a national sample of British adults
von Wagner, C., Knight, K. M., Steptoe, A., & Wardle, J. (2007) · Journal of Epidemiology & Community Health · doi:10.1136/jech.2006.053967 · Cited by 592
Bennett, I. M., Chen, J., Soroui, J., & White, S. (2009) · The Annals of Family Medicine · doi:10.1370/afm.940 · Cited by 538
Sentell, T. L., & Braun, K. L. (2012) · Journal of Health Communication · doi:10.1080/10810730.2012.712621 · Cited by 512
Schulz, P. J., & Nakamoto, K. (2012) · Patient Education and Counseling · doi:10.1016/j.pec.2012.09.006 · Cited by 503
Self-citationLindau, S. T., Tomori, C., Lyons, T., Langseth, L., Bennett, C. L., & Garcia, P. (2002) · American Journal of Obstetrics and Gynecology · doi:10.1067/mob.2002.122091 · Cited by 483
Health Disparities By Race And Class: Why Both Matter
Kawachi, I., Daniels, N., & Robinson, D. E. (2005) · Health Affairs · doi:10.1377/hlthaff.24.2.343 · Cited by 439
Limited Literacy in Older People and Disparities in Health and Healthcare Access
Sudore, R. L., Mehta, K. M., Simonsick, E. M., Harris, T. B., Newman, A. B., Satterfield, S., Rosano, C., Rooks, R. N., Rubin, S. M., Ayonayon, H. N., et al. (2006) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2006.00691.x · Cited by 429
Bennett, C. L., Ferreira, M. R., Davis, T. C., Kaplan, J., Weinberger, M., Kuzel, T. M., Seday, M. A., & Sartor, O. A. (1998) · Journal of Clinical Oncology · doi:10.1200/jco.1998.16.9.3101 · Cited by 376
Sarkar, U., Karter, A. J., Liu, J. Y., Adler, N. E., Nguyen, R., López, A., & Schillinger, D. (2010) · Journal of Health Communication · doi:10.1080/10810730.2010.499988 · Cited by 367
The Health Literacy of Parents in the United States: A Nationally Representative Study
Yin, H. S., Johnson, M., Mendelsohn, A. L., Abrams, M. A., Sanders, L., & Dreyer, B. P. (2009) · PEDIATRICS · doi:10.1542/peds.2009-1162e · Cited by 365
Defining and measuring health literacy: what can we learn from literacy studies?
Nutbeam, D. (2009) · International Journal of Public Health · doi:10.1007/s00038-009-0050-x · Cited by 339
Impact of health literacy on socioeconomic and racial differences in health in an elderly population
Howard, D. H., Sentell, T. L., & Gazmararian, J. A. (2006) · Journal of General Internal Medicine · doi:10.1111/j.1525-1497.2006.00530.x · Cited by 334
Health Literacy Skills of U.S. Adults
Rudd, R. E. (2007) · American Journal of Health Behavior · doi:10.5993/ajhb.31.s1.3 · Cited by 325
The Mechanisms Linking Health Literacy to Behavior and Health Status
Osborn, C. Y. (2011) · American Journal of Health Behavior · doi:10.5993/ajhb.35.1.11 · Cited by 314
Schillinger, D., Barton, L. R., Karter, A. J., Wang, F. M., & Adler, N. E. (2006) · Public Health Reports · doi:10.1177/003335490612100305 · Cited by 295
Literacy, self-efficacy, and HIV medication adherence
Wolf, M. S., Davis, T. C., Osborn, C. Y., Skripkauskas, S., Bennett, C. L., & Makoul, G. (2007) · Patient Education and Counseling · doi:10.1016/j.pec.2006.08.006 · Cited by 292
Patterson, A. (2004) · Routledge eBooks · doi:10.4324/9780203168073 · Cited by 291
Methodological issues in measuring health disparities.
Keppel, K. G., Pamuk, E. R., Lynch, J. W., Carter‐Pokras, O., Insun, K., Mays, V. M., Pearcy, J. N., Schoenbach, V. J., & Weissman, J. S. (2005) · PubMed · Cited by 290
Koh, H. K., Berwick, D. M., Clancy, C. M., Baur, C., Brach, C., Harris, L. M., & Zerhusen, E. (2012) · Health Affairs · doi:10.1377/hlthaff.2011.1169 · Cited by 244
Health Literacy Explains Racial Disparities in Diabetes Medication Adherence
Osborn, C. Y., Cavanaugh, K. L., Wallston, K. A., Kripalani, S. B., Elasy, T. A., Rothman, R. L., & White, R. O. (2011) · Journal of Health Communication · doi:10.1080/10810730.2011.604388 · Cited by 238
Health Literacy not Race Predicts End-of-Life Care Preferences
Volandes, A. E., Paasche‐Orlow, M. K., Gillick, M. R., Cook, E. F., Shaykevich, S., Abbo, E. D., & Lehmann, L. S. (2008) · Journal of Palliative Medicine · doi:10.1089/jpm.2007.0224 · Cited by 231
Osborn, C. Y., Paasche‐Orlow, M. K., Davis, T. C., & Wolf, M. S. (2007) · American Journal of Preventive Medicine · doi:10.1016/j.amepre.2007.07.022 · Cited by 214
Perspective: The Role of Numeracy in Health Care
Rothman, R. L., Montori, V. M., Cherrington, A., & Pignone, M. P. (2008) · Journal of Health Communication · doi:10.1080/10810730802281791 · Cited by 196
Education, literacy, and health: Mediating effects on hypertension knowledge and control
Pandit, A. U., Tang, J. W., Bailey, S. C., Davis, T. C., Bocchini, M. V., Persell, S. D., Federman, A. D., & Wolf, M. S. (2009) · Patient Education and Counseling · doi:10.1016/j.pec.2009.04.006 · Cited by 159
Racial Disparities in Health Literacy and Access to Care Among Patients With Heart Failure
Chaudhry, S. I., Herrin, J. S., Phillips, C., Butler, J., Mukerjhee, S., Murillo, J. E., Onwuanyi, A., Seto, T. B., Spertus, J. A., & Krumholz, H. M. (2010) · Journal of Cardiac Failure · doi:10.1016/j.cardfail.2010.09.016 · Cited by 131
Osborn, C. Y., Cavanaugh, K. L., Wallston, K. A., White, R. O., & Rothman, R. L. (2009) · Diabetes Care · doi:10.2337/dc09-0425 · Cited by 128
Towards understanding the links between health literacy and physical health.
Mõttus, R., Johnson, W., Murray, C. L., Wolf, M. S., Starr, J. M., & Deary, I. J. (2013) · Health Psychology · doi:10.1037/a0031439 · Cited by 125
Health literacy skills of U.S. adults.
Rudd, R. E. (2007) · PubMed · doi:10.5555/ajhb.2007.31.supp.s8 · Cited by 120
Lee, H. Y., Rhee, T. G., Kim, N. K., & Ahluwalia, J. S. (2015) · Journal of General Internal Medicine · doi:10.1007/s11606-015-3217-6 · Cited by 119
The Impact of Health Literacy and Socioeconomic Status on Asthma Disparities
Curtis, L. M., Wolf, M. S., Weiss, K. B., & Grammer, L. C. (2012) · Journal of Asthma · doi:10.3109/02770903.2011.648297 · Cited by 105
Education level, not health literacy, associated with information needs for patients with cancer
Matsuyama, R. K., Wilson-Genderson, M., Kuhn, L., Moghanaki, D. M., Vachhani, H. R., & Paasche‐Orlow, M. K. (2011) · Patient Education and Counseling · doi:10.1016/j.pec.2011.03.022 · Cited by 103
Sentell, T. L., Braun, K. L., Davis, J. W., & Davis, T. C. (2013) · Journal of Health Communication · doi:10.1080/10810730.2013.825669 · Cited by 95
Bakker, J. P., O'Keeffe, K. M., Neill, A. M., & Campbell, A. J. (2011) · Sleep · doi:10.5665/sleep.1404 · Cited by 93
Predictors of misunderstanding pediatric liquid medication instructions.
Bailey, S. C., Pandit, A. U., Yin, H. S., Federman, A. D., Davis, T. C., Parker, R. M., & Wolf, M. S. (2009) · PubMed · Cited by 92
Literacy, race, and PSA level among low-income men newly diagnosed with prostate cancer
Wolf, M. S., Knight, S. J., Lyons, E. A., Durazo-Arvizú, R., Pickard, A. S., Arseven, A., Arozullah, A. M., Colella, K. M., Ray, P., & Bennett, C. L. (2006) · Urology · doi:10.1016/j.urology.2006.01.064 · Cited by 92
Numeracy Skills Explain Racial Differences in HIV Medication Management
Waldrop‐Valverde, D., Osborn, C. Y., Rodriguez, A. E., Rothman, R. L., Kumar, M., & Jones, D. L. (2009) · AIDS and Behavior · doi:10.1007/s10461-009-9604-4 · Cited by 90
Literacy and Race as Risk Factors for Low Rates of Advance Directives in Older Adults
Waite, K. R., Federman, A. D., McCarthy, D. M., Sudore, R. L., Curtis, L. M., Baker, D. W., Wilson, E. A. H., Hasnain‐Wynia, R., Wolf, M. S., & Paasche‐Orlow, M. K. (2013) · Journal of the American Geriatrics Society · doi:10.1111/jgs.12134 · Cited by 90
Factors Associated with Health Information-Seeking in Low-Income Pregnant Women
Shieh, C., Broome, M. E., & Stump, T. E. (2010) · Women & Health · doi:10.1080/03630242.2010.506152 · Cited by 87
Wang, C., Li, H., Li, L., Xu, D., Kane, R. L., & Meng, Q. (2013) · Health and Quality of Life Outcomes · doi:10.1186/1477-7525-11-153 · Cited by 85
Low Health Literacy and Poor Health Status in Asian Americans and Pacific Islanders in Hawai'i
Sentell, T. L., Baker, K. K., Onaka, A. T., & Braun, K. L. (2011) · Journal of Health Communication · doi:10.1080/10810730.2011.604390 · Cited by 83
Uncertainty About Advance Care Planning Treatment Preferences Among Diverse Older Adults
Sudore, R. L., Schillinger, D., Knight, S. J., & Fried, T. R. (2010) · Journal of Health Communication · doi:10.1080/10810730.2010.499982 · Cited by 81
Chen, Y., & Feeley, T. H. (2013) · Health Communication · doi:10.1080/10410236.2013.807904 · Cited by 77
Brega, A. G., Ang, A., Vega, W. A., Jiang, L., Beals, J., Mitchell, C. M., MOORE, K. R., Manson, S. M., Acton, K. J., & Roubideaux, Y. D. (2012) · Patient Education and Counseling · doi:10.1016/j.pec.2012.03.008 · Cited by 76
Bains, S. S., & Egede, L. E. (2011) · BMC Complementary and Alternative Medicine · doi:10.1186/1472-6882-11-138 · Cited by 75
Waldrop‐Valverde, D., Jones, D. L., Jayaweera, D. T., Gonzalez, P., Romero, J., & Ownby, R. L. (2008) · AIDS and Behavior · doi:10.1007/s10461-008-9425-x · Cited by 72
Predicting Cancer Risk Knowledge and Information Seeking: The Role of Social and Cognitive Factors
Hovick, S. R. A., Liang, M.-C., & Kahlor, L. A. (2013) · Health Communication · doi:10.1080/10410236.2012.763204 · Cited by 66
Baker, D. W. (1999) · Journal of General Internal Medicine · doi:10.1046/j.1525-1497.1999.00342.x · Cited by 61
Racial/Ethnic Disparities in Knowledge about One's Breast Cancer Characteristics
Freedman, R., Kouri, E., West, D. W., & Keating, N. L. (2015) · Cancer · doi:10.1002/cncr.28977 · Cited by 58
Song, L., Weaver, M. A., Chen, R. C., Bensen, J. T., Fontham, E. T. H., Mohler, J. L., Mishel, M. H., Godley, P. A., & Sleath, B. L. (2014) · Patient Education and Counseling · doi:10.1016/j.pec.2014.08.019 · Cited by 52
Gardiner, P. M., Mitchell, S. E., Filippelli, A. C., Sadikova, E., White, L. F., Paasche‐Orlow, M. K., & Jack, B. W. (2013) · Journal of Health Communication · doi:10.1080/10810730.2013.830663 · Cited by 45
Smith, P. C., Brice, J. H., & Lee, J. (2012) · Journal of the National Medical Association · doi:10.1016/s0027-9684(15)30218-2 · Cited by 43
Immigration, Generation and Self-rated Health in Canada: On the Role of Health Literacy
Omariba, D. W. R., & Ng, E. (2011) · Canadian Journal of Public Health · doi:10.1007/bf03404049 · Cited by 41
Kaphingst, K. A., Stafford, J. D., McGowan, L. D., Seo, J., Lachance, C. R., & Goodman, M. S. (2015) · Health Psychology · doi:10.1037/hea0000177 · Cited by 39
Sperber, N. R., Bosworth, H. B., Coffman, C. J., Lindquist, J. H., Oddone, E. Z., Weinberger, M., & Allen, K. D. (2013) · Health Education Research · doi:10.1093/her/cyt043 · Cited by 34
Langford, A. T., Resnicow, K., Roberts, J. S., & Zikmund‐Fisher, B. J. (2012) · Journal of Genetic Counseling · doi:10.1007/s10897-011-9478-2 · Cited by 30
Disparities in Using Technology to Access Health Information: Race Versus Health Literacy
Chakkalakal, R. J., Kripalani, S. B., Schlundt, D. G., Elasy, T. A., & Osborn, C. Y. (2014) · Diabetes Care · doi:10.2337/dc13-1984 · Cited by 25
Health literacy and disability: differences between generations of Canadian immigrants
Omariba, D. W. R., & Ng, E. (2014) · International Journal of Public Health · doi:10.1007/s00038-014-0640-0 · Cited by 15
Cited by
Sorted by citations
Understanding and Responding to Health Literacy as a Social Determinant of Health
Nutbeam, D., & Lloyd, J. E. (2021) · Annual Review of Public Health · doi:10.1146/annurev-publhealth-090419-102529 · Cited by 1,178
Stormacq, C., Van den Broucke, S., & Wosinski, J. (2019) · Health Promotion International · doi:10.1093/heapro/day062 · Cited by 928
Wolf, M. S., Serper, M., Opsasnick, L. A., O’Conor, R. M., Curtis, L. M., Benavente, J. Y., Wismer, G. A., Batio, S., Eifler, M. R., Zheng, P., et al. (2020) · Annals of Internal Medicine · doi:10.7326/m20-1239 · Cited by 563
Akalu, Y., Ayelign, B., & Molla, M. D. (2020) · Infection and Drug Resistance · doi:10.2147/idr.s258736 · Cited by 353
McCaffery, K. J., Dodd, R. H., Cvejic, E., Ayre, J., Batcup, C., Isautier, J., Copp, T., Bonner, C., Pickles, K. M., Nickel, B., et al. (2020) · Public Health Research & Practice · doi:10.17061/phrp30342012 · Cited by 293
Metadata
- Authors
- Mantwill, S., Monestel-Umaña, S., & Schulz, P. J.
- Affiliations
- Università della Svizzera italiana (CH)
- Corresponding author
- Mantwill, Sarah
- Venue
- PLOS ONE
- Publisher
- Public Library of Science (PLoS)
- Published
- 2015-12-23
- Volume
- 10
- Issue
- 12
- Pages
- e0145455
- ISSN
- 1932-6203 (ISSN-L)
- PMC
- PMC4689381
- OpenAlex
- W2199607157
- Cited by
- 395
- References
- 73
- Citations by year
- 2026: 36 · 2025: 45 · 2024: 44 · 2023: 35 · 2022: 41 · 2021: 54 · 2020: 72 · 2019: 30 · 2018: 19 · 2017: 15 · 2016: 3
- FWCI
- 2.21
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- PLoS ONE (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- RePEc: Research Papers in Economics (acceptedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Figshare (submittedVersion, cc-by)
- Topics
- Health Sciences › Health Professions › General Health Professions › Health Literacy and Information Accessibility
- Social Sciences › Health › Health disparities and outcomes
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Cultural Competency in Health Care
- Keywords
- health literacy, health disparities, racial and ethnic disparities, educational inequality, self-rated health, medication adherence, numeracy, social determinants of health, mediation pathways
- MeSH terms
- Ethnicity, Humans, Health Knowledge, Attitudes, Practice, Health Status Disparities, Health Literacy
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review