miR-195 inhibits macrophages pro-inflammatory profile and impacts the crosstalk with smooth muscle cells
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Dysfunction in one single miRNA can concomitantly impair several biological functions by acting on distinct mRNA targets.
“Remarkably, dysfunction in one single miRNA can concomitantly impair several biological functions by acting on distinct mRNA targets, as previously described by us16–20.”
From TNF-alpha-induced microglia activation requires miR-342: Impact on NF-kB signaling and neurotoxicity (2020) · cites this paper as [20]
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The MIQE guidelines: minimum information for publication of quantitative real-time PCR experiments
Bustin, S. A., Benes, V., Garson, J. A., Hellemans, J., Huggett, J., Kubista, M., Mueller, R., Nolan, T., Pfaffl, M. W., Shipley, G. L., et al. (2009) · Clinical Chemistry · doi:10.1373/clinchem.2008.112797 · Cited by 16,303 · cited 1× · see citing works
“qPCR reactions were performed in duplicate in a MyCycler Thermal Cycler (Bio-Rad) and relative expression levels were calculated using the quantification cycle (Cq) method, according to MIQE guidelines [22].”
MethodProgress and challenges in translating the biology of atherosclerosis
Libby, P., Ridker, P. M., & Hansson, G. K. (2011) · Nature · doi:10.1038/nature10146 · Cited by 4,010 · see citing works
The history of toll-like receptors - redefining innate immunity
O'Neill, L. A. J., Golenbock, D., & Bowie, A. G. (2013) · Nature reviews. Immunology · doi:10.1038/nri3446 · Cited by 1,765 · see citing works
MicroRNA let-7c Regulates Macrophage Polarization
Banerjee, S., Xie, N., Cui, H., Tan, Z., Yang, S., Icyuz, M., Abraham, E., & Liu, G. (2013) · The Journal of Immunology · doi:10.4049/jimmunol.1202496 · Cited by 320 · see citing works
miR-125a-5p Regulates Differential Activation of Macrophages and Inflammation
Banerjee, S., Cui, H., Xie, N., Tan, Z., Yang, S., Icyuz, M., Thannickal, V. J., Abraham, E., & Liu, G. (2013) · Journal of Biological Chemistry · doi:10.1074/jbc.m112.426866 · Cited by 258 · see citing works
Next-generation sequencing of microRNAs uncovers expression signatures in polarized macrophages
Cobos Jiménez, V., Bradley, E. J., Willemsen, A. M., van Kampen, A. H. C., Baas, F., & Kootstra, N. A. (2014) · Physiological Genomics · doi:10.1152/physiolgenomics.00140.2013 · Cited by 103 · see citing works
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TNF-alpha-induced microglia activation requires miR-342: Impact on NF-kB signaling and neurotoxicity
Brás, J. P., Bravo, J., Freitas, J., Barbosa, M. A., Santos, S. G., Summavielle, T., & Almeida, M. I. (2020) · Cell Death & Disease · doi:10.1038/s41419-020-2626-6 · Cited by 236 · see citing works
Self-citationWu, J., Jin, L., Tan, J.-Y., Chen, X.-F., Wang, Q.-Q., Yuan, G.-Y., & Chen, T.-X. (2021) · Annals of Translational Medicine · doi:10.21037/atm-21-1375 · Cited by 17 · see citing works
MicroRNAs As Novel Biomarkers and Potential Therapeutic Options for Inflammatory Cardiomyopathy
Aleshcheva, G., Baumeier, C., Harms, D., Bock, C.-T., Escher, F., & Schultheiss, H.-P. (2023) · ESC Heart Failure · doi:10.1002/ehf2.14523 · Cited by 17 · see citing works
- Authors
- Bras, J. P., Silva, A. M., Calin, G. A., Barbosa, M. A., Santos, S. G., & Almeida, M. I.
- Venue
- PLOS ONE
- Publisher
- Public Library of Science (PLoS)
- Published
- 2017-11-22
- Volume
- 12
- Issue
- 11
- Pages
- e0188530
- ISSN
- 1932-6203
- PMC
- PMC5699821
- Cited by
- 49
- References
- 6
- Language
- en
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