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Cited by 400

The DOI matches its Crossref record; 31 of the 31 references it cites were found in a registry or an index.

Netherlands Twin Register: From Twins to Twin Families

Open access
Boomsma, Dorret I., de Geus, Eco J. C., Vink, Jacqueline M., Stubbe, Janine H., Distel, Marijn A., Hottenga, Jouke-Jan, Posthuma, Danielle, van Beijsterveldt, Toos C. E. M., Hudziak, James J., Bartels, Meike, Willemsen, Gonneke·2006·Twin Research and Human Genetics

Abstract

In the late 1980s The Netherlands Twin Register (NTR) was established by recruiting young twins and multiples at birth and by approaching adolescent and young adult twins through city councils. The Adult NTR (ANTR) includes twins, their parents, siblings, spouses and their adult offspring. The number of participants in the ANTR who take part in survey and / or laboratory studies is over 22,000 subjects. A special group of participants consists of sisters who are mothers of twins. In the Young NTR (YNTR), data on more than 50,000 young twins have been collected. Currently we are extending the YNTR by including siblings of twins. Participants in YNTR and ANTR have been phenotyped every 2 to 3 years in longitudinal survey studies, since 1986 and 1991 for the YNTR and ANTR, respectively. The resulting large population-based datasets are used for genetic epidemiological studies and also, for example, to advance phenotyping through the development of new syndrome scales based on existing items from other inventories. New research developments further include brain imaging studies in selected and unselected groups, clinical assessment of psychopathology through interviews, and cross-referencing the NTR database to other national databases. A large biobank enterprise is ongoing in the ANTR in which blood and urine samples are collected for genotyping, expression analysis, and metabolomics studies. In this paper we give an update on the YNTR and ANTR phenotyping and on the ongoing ANTR biobank studies.

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Research works printed but not linked: 11

  1. 10.1375/twin.3.4.323 · doi:10.1375/twin.3.4.323
  2. 10.1002/(SICI)1098-2272(1996)13:1<49::AID-GEPI5>3.0.CO;2-1 · doi:10.1002/(sici)1098-2272(1996)13:1<49::aid-gepi5>3.0.co;2-1
  3. 10.1375/twin.5.5.401 · doi:10.1375/twin.5.5.401
  4. 10.1375/twin.9.3.424 · doi:10.1375/twin.9.3.424
  5. 10.1375/twin.7.6.556 · doi:10.1375/twin.7.6.556
  6. Middeldorp, C. M., Cath, D. C., Van den Berg, M., Beem, A. L., Van Dyck, R. & Boomsma, D. I. (2006). The association of personality and anxious and depressive psychopathology. In T. Canli (Ed.), The biological basis of personality and individual differences (pp. 251-272). New York: Guilford Press.
  7. 10.1375/twin.7.6.548 · doi:10.1375/twin.7.6.548
  8. 10.1093/humrep/deg441 · doi:10.1093/humrep/deg441
  9. 10.1375/twin.3.3.134 · DOI · Paper page
  10. Snieder H., 1997, American Journal of Human Genetics, 60, 638
  11. 10.1375/twin.7.6.564 · doi:10.1375/twin.7.6.564

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Metadata

Authors
Boomsma, D. I., de Geus, E. J. C., Vink, J. M., Stubbe, J. H., Distel, M. A., Hottenga, J.-J., Posthuma, D., van Beijsterveldt, T. C. E. M., Hudziak, J. J., Bartels, M., & Willemsen, G.
Venue
Twin Research and Human Genetics
Published
2006-12-01
Volume
9
Issue
6
Pages
849-857
ISSN
  • 1832-4274 (ISSN-L)
  • 0000-0000
OpenAlex
W1988470975
Cited by
400
References
31
FWCI
29.84
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Netherlands Twin Register: From Twins to Twin Families. https://app.cochat.ai/papers/10.1375/183242706779462426
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Boomsma, D. I., de Geus, E. J. C., Vink, J. M., Stubbe, J. H., Distel, M. A., Hottenga, J.-J., Posthuma, D., van Beijsterveldt, T. C. E. M., Hudziak, J. J., Bartels, M., & Willemsen, G. (2006). Netherlands Twin Register: From Twins to Twin Families. Twin Research and Human Genetics. https://doi.org/10.1375/183242706779462426

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